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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Chemical and Drug Induced Liver Injury
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Accession:DOID:9007383 term browser browse the term
Definition:A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
Synonyms:exact_synonym: Chemically Induced Liver Toxicity;   Drug Induced Acute Liver Injury;   Drug Induced Liver Disease;   Drug Induced Liver Injury;   Drug-Induced Liver Diseases;   Drug-Induced Liver Injuries;   Toxic Hepatitis;   chemically-induced liver toxicities;   hepatotoxicity;   toxic hepatitides
 narrow_synonym: Drug-induced liver injury due to flucloxacillin
 primary_id: MESH:D056486
 alt_id: RDO:0007742
 xref: EFO:0004228;   EFO:0011052;   NCI:C84427


show annotations for term's descendants           Sort by:
Chemical and Drug Induced Liver Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AASS aminoadipate-semialdehyde synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr14:59,950,123...59,993,457
Ensembl chr14:59,951,216...60,000,212 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 susceptibility
severity		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP::2677G>T/A(rs2032582)(human)		 CTD
RGD		 PMID:20623750 PMID:26134275 PMID:27296832 RGD:11041130 RGD:14700895 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 severity ISO DNA:SNP: :rs2287616(human) RGD PMID:27293027 RGD:14402413 NCBI chr36:13,742,895...13,835,312
Ensembl chr36:13,746,964...13,834,974 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18466103 NCBI chr 6:27,855,702...27,950,140
Ensembl chr 6:27,855,702...27,989,331 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 susceptibility ISO DNA:polymorphism:promoter:-24C>T(human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17241877 PMID:18381794 PMID:18466103 PMID:25196354 RGD:14700812 RGD:14700814 NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740 		JBrowse link
G ABI1 abl interactor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:6,941,752...7,059,466
Ensembl chr 2:6,941,900...7,057,684 		JBrowse link
G ACE angiotensin I converting enzyme ISO mRNA:increased expression:liver (rat) RGD PMID:25143335 RGD:25671447 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358 		JBrowse link
G ACOX3 acyl-CoA oxidase 3, pristanoyl ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 3:60,154,012...60,205,696
Ensembl chr 3:60,153,775...60,203,554 		JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr16:45,735,675...45,806,235
Ensembl chr16:45,735,703...45,804,970 		JBrowse link
G ACTB actin beta ISO mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:22563491 PMID:25231249 RGD:9587759 NCBI chr 6:12,421,006...12,424,449
Ensembl chr 6:12,418,932...12,462,845 		JBrowse link
G ACTN4 actinin alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:114,354,993...114,427,997
Ensembl chr 1:114,309,693...114,427,991 		JBrowse link
G ACTR3 actin related protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr19:35,097,968...35,133,330
Ensembl chr19:35,098,639...35,169,724 		JBrowse link
G ADA adenosine deaminase ISO protein:increased expression:liver RGD PMID:21161045 RGD:5128859 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24646716 NCBI chr28:40,853,665...40,865,604
Ensembl chr28:40,855,509...40,863,747 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:20709802 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844 		JBrowse link
G ADIPOR2 adiponectin receptor 2 severity ISO associated with obesity, LPS;mRNA:decreased expression:liver (rat) RGD PMID:23838384 RGD:8695926 NCBI chr27:43,739,269...43,840,116
Ensembl chr27:43,741,679...43,878,467 		JBrowse link
G ADORA2B adenosine A2b receptor ISO CTD Direct Evidence: therapeutic CTD PMID:35292334 NCBI chr 5:39,884,375...39,908,214 JBrowse link
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29499335 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:decreased expression:liver (rat)		 CTD
RGD		 PMID:21890736 PMID:28959666 PMID:34848246 RGD:401794432 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25743375 NCBI chr  X:101,275,027...101,307,551
Ensembl chr  X:101,275,017...101,307,367 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:29763686 PMID:32805337 RGD:27226688 NCBI chr15:14,792,398...14,808,805
Ensembl chr15:14,742,012...14,808,592 		JBrowse link
G ALB albumin treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18779383 PMID:22310181 PMID:27567545 RGD:14694844 NCBI chr13:62,133,747...62,169,349
Ensembl chr13:62,053,814...62,294,709 		JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr10:33,310,523...33,365,677
Ensembl chr10:33,310,558...33,365,228 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member severity
susceptibility		 ISO DNA:deletion:exon 3 (mouse)
protein:increased expression:liver		 RGD PMID:21138988 PMID:24492981 PMID:30121625 RGD:14975148 RGD:15036810 RGD:7241599 NCBI chr26:9,319,109...9,361,021 JBrowse link
G ALDH9A1 aldehyde dehydrogenase 9 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr38:17,644,464...17,664,462
Ensembl chr38:17,644,459...17,663,886 		JBrowse link
G ALDOB aldolase, fructose-bisphosphate B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16115720 NCBI chr11:58,150,621...58,166,266
Ensembl chr11:58,150,967...58,176,319 		JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18779383 NCBI chr11:68,338,644...68,353,366
Ensembl chr11:68,338,389...68,351,994 		JBrowse link
G ANXA2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281 		JBrowse link
G ANXA6 annexin A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 4:58,091,186...58,140,102
Ensembl chr 4:58,091,251...58,139,372 		JBrowse link
G APOA1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943 		JBrowse link
G APOE apolipoprotein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G APOH apolipoprotein H ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:plasma:		 CTD
RGD		 PMID:16099942 PMID:23288050 RGD:10054107 NCBI chr 9:14,082,648...14,095,186
Ensembl chr 9:14,082,541...14,095,185 		JBrowse link
G ARG1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22872058 NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20935161 Ensembl chr17:59,941,353...60,010,867
Ensembl chr17:59,941,353...60,010,867 		JBrowse link
G ARNTL aryl hydrocarbon receptor nuclear translocator like ISO CTD Direct Evidence: therapeutic CTD PMID:36602574 NCBI chr21:36,254,235...36,323,915
Ensembl chr21:36,290,070...36,323,622 		JBrowse link
G ATG5 autophagy related 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22491424 NCBI chr12:63,565,859...63,692,383
Ensembl chr12:63,567,568...63,683,485 		JBrowse link
G ATOH8 atonal bHLH transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr17:39,255,725...39,280,022 JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 8:41,332,581...41,354,058
Ensembl chr 8:41,333,021...41,354,320 		JBrowse link
G B9D2 B9 domain containing 2 treatment ISO RGD PMID:27516150 RGD:14995464 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO RGD PMID:25447754 RGD:10053709 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17906064 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464 		JBrowse link
G BDH1 3-hydroxybutyrate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr33:30,407,021...30,422,735
Ensembl chr33:30,406,338...30,436,366 		JBrowse link
G BDKRB2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30685357 NCBI chr 8:64,974,588...65,005,682
Ensembl chr 8:64,974,997...65,003,407 		JBrowse link
G BLVRB biliverdin reductase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:113,244,484...113,258,170
Ensembl chr 1:113,244,503...113,258,073 		JBrowse link
G BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr38:14,834,642...14,857,242
Ensembl chr38:14,834,643...14,857,227 		JBrowse link
G BRD4 bromodomain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr20:46,844,795...46,927,620
Ensembl chr20:46,891,514...46,927,608 		JBrowse link
G BTD biotinidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15469856 NCBI chr23:27,037,640...27,069,544
Ensembl chr23:27,037,921...27,069,456 		JBrowse link
G C3 complement C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761 		JBrowse link
G CA3 carbonic anhydrase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 PMID:25231249 NCBI chr29:31,935,192...31,945,585
Ensembl chr29:31,935,172...31,980,579 		JBrowse link
G CABP1 calcium binding protein 1 ISO protein:increased expression:liver RGD PMID:21138988 RGD:7241599 NCBI chr26:16,492,484...16,523,265 JBrowse link
G CADPS2 calcium dependent secretion activator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr14:60,109,253...60,465,982
Ensembl chr14:60,107,538...60,556,817 		JBrowse link
G CANX calnexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr11:1,966,612...1,998,620
Ensembl chr11:1,927,888...1,998,604 		JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr15:2,886,661...2,913,975 JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:25447754 RGD:10053709 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822 		JBrowse link
G CAST calpastatin ISO RGD PMID:16871587 RGD:5683869 NCBI chr 3:12,920,514...13,031,974
Ensembl chr 3:12,922,453...13,031,959 		JBrowse link
G CAT catalase ISO protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:20623750 PMID:21138988 PMID:25231249 RGD:7241599 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447 		JBrowse link
G CCDC80 coiled-coil domain containing 80 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr33:17,105,086...17,141,380
Ensembl chr33:17,105,086...17,139,896 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20623750 PMID:21813474 PMID:30663942 RGD:14995458 RGD:14995466 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 susceptibility ISO acetaminophen RGD PMID:24770590 RGD:14401733 NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952 		JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 7:41,566,274...41,583,903
Ensembl chr 7:41,566,292...41,584,863 		JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr34:4,035,851...4,049,131
Ensembl chr34:4,035,857...4,049,244 		JBrowse link
G CDC25B cell division cycle 25B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr24:17,552,206...17,561,791
Ensembl chr24:17,553,316...17,561,759 		JBrowse link
G CDS1 CDP-diacylglycerol synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr32:8,349,033...8,416,451
Ensembl chr32:8,349,027...8,415,295 		JBrowse link
G CELA1 chymotrypsin like elastase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr27:3,542,327...3,560,777
Ensembl chr27:3,542,309...3,560,777 		JBrowse link
G CFAP20 cilia and flagella associated protein 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:58,445,932...58,459,437
Ensembl chr 2:58,445,927...58,459,779 		JBrowse link
G CFH complement factor H ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr38:2,878,677...2,956,226 JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20197374 NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613 		JBrowse link
G CLU clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr25:29,982,811...29,999,565
Ensembl chr25:29,982,811...29,999,563 		JBrowse link
G COL14A1 collagen type XIV alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr13:19,033,423...19,249,189
Ensembl chr13:19,011,897...19,248,568 		JBrowse link
G COL3A1 collagen type III alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16679477 NCBI chr36:30,488,250...30,526,367
Ensembl chr36:30,488,488...30,536,765 		JBrowse link
G COMT catechol-O-methyltransferase ISO protein:decreased expression:liver RGD PMID:21138988 RGD:7241599 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008 		JBrowse link
G COQ9 coenzyme Q9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:58,964,221...58,977,589
Ensembl chr 2:58,964,318...58,977,573 		JBrowse link
G CP ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr23:43,969,297...44,033,226
Ensembl chr23:43,969,435...44,030,369 		JBrowse link
G CPB2 carboxypeptidase B2 ISO mRNA,protein:increased expression,increased activity:liver,plasma RGD PMID:19386599 RGD:7243112 NCBI chr22:5,074,805...5,126,635
Ensembl chr22:5,074,816...5,126,170 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr37:18,308,164...18,428,487
Ensembl chr37:18,143,986...18,427,697 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO mRNA:decreased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chr18:49,136,691...49,190,117
Ensembl chr18:49,136,691...49,190,117 		JBrowse link
G CRP C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166 		JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:20005281 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108 		JBrowse link
G CTNNB1 catenin beta 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19679878 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G CTSE cathepsin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr38:2,368,711...2,380,554
Ensembl chr38:2,369,265...2,380,459 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: therapeutic CTD PMID:11739529 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33814510 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28762043 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33814510 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 ISO mRNA, protein:decreased expression:kidney (mouse) RGD PMID:26476181 RGD:25671412 NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911 		JBrowse link
G CYP2A13 cytochrome P450 family 2 subfamily A polypeptide 13 ISO CTD Direct Evidence: therapeutic CTD PMID:23628428 NCBI chr 1:112,932,246...112,938,248
Ensembl chr 1:112,931,985...112,938,350 		JBrowse link
G CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21741958 NCBI chr 1:112,900,508...112,906,745
Ensembl chr 1:112,900,403...112,907,076 		JBrowse link
G CYP2B6 cytochrome P450 2B11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28762043 PMID:33814510 NCBI chr 1:112,817,561...112,833,294
Ensembl chr 1:112,816,502...112,833,293 		JBrowse link
G CYP2C41 cytochrome P450 2C41 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14971821 PMID:21741958 PMID:25226513 PMID:28762043 PMID:33814510
G CYP2D15 cytochrome P450 family 2 subfamily D member 15 ISO DNA:hypermethylation:promoter RGD PMID:27490558 RGD:14700879 NCBI chr10:23,255,259...23,259,380
Ensembl chr10:23,255,249...23,259,298 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 treatment ISO associated with Endotoxemia
DNA:hypermethylation:promoter
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12668988 PMID:16770646 PMID:21741958 PMID:25681370 PMID:27324775 More... RGD:14700872 RGD:14700873 RGD:14700878 RGD:14700879 RGD:14700901 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754 		JBrowse link
G CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28762043 NCBI chr 6:9,836,685...9,869,520
Ensembl chr 6:9,777,659...9,869,352 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25448281 NCBI chr23:11,965,685...11,968,994
Ensembl chr23:11,967,341...11,968,846 		JBrowse link
G DBT dihydrolipoamide branched chain transacylase E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 6:49,753,233...49,805,493
Ensembl chr 6:49,753,323...49,805,882 		JBrowse link
G DDB1 damage specific DNA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr18:55,064,720...55,097,623
Ensembl chr18:55,064,729...55,097,627 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr21:22,833,659...22,850,300
Ensembl chr21:22,834,518...22,851,260 		JBrowse link
G DHFR dihydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19648163 NCBI chr 3:26,521,214...26,556,065 JBrowse link
G DHRS7 dehydrogenase/reductase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 8:35,251,988...35,269,880
Ensembl chr 8:35,251,975...35,269,869 		JBrowse link
G DLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility ISO DNA:polymorphism: :HLA-DQB1*05(human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism, haplotype		 RGD
CTD		 PMID:21570397 PMID:25250564 PMID:26959717 RGD:11573514 RGD:36174016 NCBI chr12:2,305,307...2,307,711 JBrowse link
G DLA88 MHC class I DLA-88 ISO ClinVar Annotator: match by term: Drug-induced liver injury due to flucloxacillin ClinVar PMID:11888582 PMID:11943262 PMID:12462283 PMID:15024131 PMID:15247624 More... NCBI chr12:892,442...895,691
Ensembl chr12:892,388...1,021,690 		JBrowse link
G DLAT dihydrolipoamide S-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 5:21,062,833...21,094,235
Ensembl chr 5:21,064,026...21,094,153 		JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr14:48,879,963...48,885,616
Ensembl chr14:48,879,914...48,884,361 		JBrowse link
G DNAJC12 DnaJ heat shock protein family (Hsp40) member C12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr 4:19,096,656...19,147,722
Ensembl chr 4:19,096,656...19,147,655 		JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 ISO protein:increased expression:liver (rat) RGD PMID:16538043 RGD:2301096 NCBI chr 5:45,055,294...45,119,595
Ensembl chr 5:44,884,283...45,120,203 		JBrowse link
G DSC2 desmocollin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 7:58,369,316...58,402,028
Ensembl chr 7:58,322,959...58,457,978 		JBrowse link
G ECHDC1 ethylmalonyl-CoA decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:66,012,245...66,073,008
Ensembl chr 1:66,012,782...66,073,000 		JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr28:40,939,856...40,947,694
Ensembl chr28:40,939,961...40,946,167 		JBrowse link
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr20:12,444,013...12,473,188
Ensembl chr20:12,452,730...12,472,069 		JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25411909 NCBI chr 6:11,447,225...11,478,611
Ensembl chr 6:11,447,081...11,478,658 		JBrowse link
G EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 4:21,339,037...21,364,224
Ensembl chr 4:21,339,045...21,358,072 		JBrowse link
G ENDOG endonuclease G ISO protein:decreased expression:mitochondrion: RGD PMID:22509279 RGD:9685364 NCBI chr 9:54,809,470...54,812,795
Ensembl chr 9:54,809,530...54,813,042 		JBrowse link
G ENG endoglin ISO protein:increased expression:liver (rat) RGD PMID:21146604 RGD:7257529 NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064 		JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 PMID:25231249 NCBI chr 5:62,300,805...62,314,508
Ensembl chr 5:62,300,808...62,304,093 		JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO protein:increased activity:serum: RGD PMID:17850827 RGD:9685426 NCBI chr13:18,586,886...18,697,339
Ensembl chr13:18,587,129...18,697,324 		JBrowse link
G EPHX1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 7:38,964,319...39,004,902
Ensembl chr 7:38,964,338...38,999,238 		JBrowse link
G ERLEC1 endoplasmic reticulum lectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr10:54,815,592...54,845,776
Ensembl chr10:54,815,638...54,845,080 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30538632 NCBI chr 9:11,930,614...12,006,724
Ensembl chr 9:11,934,965...12,006,814 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO RGD PMID:22019897 RGD:11041813 NCBI chr35:6,186,750...6,347,522
Ensembl chr35:6,187,235...6,349,773 		JBrowse link
G F2RL3 F2R like thrombin or trypsin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20974703 NCBI chr20:45,738,587...45,740,564
Ensembl chr20:45,738,587...45,740,473 		JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22407844 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G FADD Fas associated via death domain treatment ISO RGD PMID:25447754 PMID:26062544 RGD:10053709 RGD:11341803 NCBI chr18:48,087,447...48,094,497 JBrowse link
G FADS1 fatty acid desaturase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr18:54,659,406...54,672,803
Ensembl chr18:54,659,406...54,670,623 		JBrowse link
G FADS2 fatty acid desaturase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr18:54,552,105...54,581,553
Ensembl chr18:54,553,366...54,659,654 		JBrowse link
G FAS Fas cell surface death receptor ISO protein:increased expression:liver (rat) RGD PMID:16831245 RGD:8662853 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 9:233,105...249,573
Ensembl chr 9:232,963...249,092 		JBrowse link
G FCMR Fc mu receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 7:6,046,270...6,064,063
Ensembl chr 7:6,048,814...6,064,013 		JBrowse link
G FGA fibrinogen alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20974703 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975 		JBrowse link
G FGF21 fibroblast growth factor 21 severity ISO mRNA:increased expression:liver (rat) RGD PMID:29883717 RGD:15045603 NCBI chr 1:107,571,449...107,576,630
Ensembl chr 1:107,571,446...107,573,281 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21135413 NCBI chr25:11,231,958...11,410,379
Ensembl chr25:11,231,737...11,407,621 		JBrowse link
G FMO3 flavin containing dimethylaniline monoxygenase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:24973094 NCBI chr 7:27,720,420...27,745,522
Ensembl chr 7:27,720,420...27,845,626 		JBrowse link
G FTL ferritin light chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:107,418,457...107,419,923
Ensembl chr 1:107,418,458...107,419,923 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 ISO mRNA:decreased expression:liver (mouse) RGD PMID:28189721 RGD:14695531 NCBI chr 9:20,132,973...20,143,642
Ensembl chr 9:20,132,978...20,143,642 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase treatment ISO RGD PMID:21864513 RGD:10449168 NCBI chr  X:122,217,317...122,231,862
Ensembl chr  X:122,205,683...122,231,678 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 6:77,393,026...77,396,473
Ensembl chr 6:77,393,036...77,396,618 		JBrowse link
G GANAB glucosidase II alpha subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr18:54,004,296...54,019,148
Ensembl chr18:54,003,689...54,018,157 		JBrowse link
G GC GC vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr13:60,795,305...60,828,038
Ensembl chr13:60,795,305...60,827,929 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17573345 PMID:19481141 RGD:10402383 NCBI chr12:20,999,815...21,047,779
Ensembl chr12:21,000,792...21,047,779 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 6:55,204,602...55,244,217 JBrowse link
G GDA guanine deaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:85,506,598...85,586,212
Ensembl chr 1:85,444,917...85,586,163 		JBrowse link
G GDI1 GDP dissociation inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr  X:122,141,633...122,146,724
Ensembl chr  X:122,141,566...122,146,824 		JBrowse link
G GFER growth factor, augmenter of liver regeneration treatment ISO RGD PMID:15968720 PMID:22033404 RGD:9685722 RGD:9685727 NCBI chr 6:38,948,927...38,951,300
Ensembl chr 6:38,949,484...38,951,703 		JBrowse link
G GGH gamma-glutamyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21219404 NCBI chr29:13,143,881...13,165,028
Ensembl chr29:13,134,232...13,165,028 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO RGD PMID:10934156 RGD:14701049 NCBI chr26:28,301,455...28,315,029 JBrowse link
G GLUD1 glutamate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33483742 NCBI chr 4:34,629,046...34,662,711 JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr28:12,352,658...12,377,960
Ensembl chr28:12,352,659...12,414,579 		JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr27:4,614,878...4,622,013
Ensembl chr27:4,614,864...4,621,922 		JBrowse link
G GPT glutamic--pyruvic transaminase treatment ISO protein:increased expression, activity:serum:
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:145039 PMID:19085960 PMID:19481104 PMID:21772750 PMID:27293452 More... RGD:14975162 RGD:14975166 RGD:14975168 RGD:14975249 NCBI chr13:37,923,757...37,927,843
Ensembl chr13:37,924,422...37,926,156 		JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 ISO protein:increased expression, activity:serum: RGD PMID:19085960 RGD:14975249 NCBI chr15:8,238,295...8,250,789 JBrowse link
G GRK4 G protein-coupled receptor kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 3:61,233,066...61,331,094
Ensembl chr 3:61,079,904...61,330,290 		JBrowse link
G GSN gelsolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G GSR glutathione-disulfide reductase treatment ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver		 RGD
CTD		 PMID:23554813 PMID:24154663 PMID:25226513 PMID:28069987 RGD:10401878 RGD:7257532 NCBI chr16:33,633,949...33,680,411
Ensembl chr16:33,633,968...33,679,752 		JBrowse link
G GSTA4 glutathione S-transferase alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr12:20,426,724...20,443,200
Ensembl chr12:20,426,726...20,443,200 		JBrowse link
G GSTM3 glutathione S-transferase mu 3 ISO CTD Direct Evidence: therapeutic CTD PMID:25743375 NCBI chr 6:42,187,869...42,191,274
Ensembl chr 6:42,187,967...42,191,273 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr28:16,569,421...16,579,239
Ensembl chr28:16,569,066...16,619,880 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 PMID:25226513 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182 		JBrowse link
G H2AX H2A.X variant histone treatment ISO RGD PMID:23265463 RGD:8693741 NCBI chr 5:14,765,625...14,766,590
Ensembl chr 5:14,766,126...14,766,557 		JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr17:20,307,207...20,355,659
Ensembl chr17:20,307,226...20,355,508 		JBrowse link
G HAMP hepcidin antimicrobial peptide ISO mRNA:increased expression:hepatocyte RGD PMID:24373749 RGD:11041724 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619 		JBrowse link
G HAO2 hydroxyacid oxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr17:56,505,463...56,529,441
Ensembl chr17:56,505,506...56,528,954 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 4:53,012,223...53,066,611
Ensembl chr 4:53,046,970...53,128,952
Ensembl chr 4:53,046,970...53,128,952 		JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:21570397 NCBI chr12:2,151,409...2,164,564 JBrowse link
G HMGB1 high mobility group box 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19783637 PMID:29091898 RGD:15090820 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD		 PMID:18227147 PMID:22688006 PMID:22886620 PMID:29091898 RGD:10762620 RGD:15090820 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773 		JBrowse link
G HPD 4-hydroxyphenylpyruvate dioxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 PMID:22872058 NCBI chr26:7,430,891...7,440,643
Ensembl chr26:7,430,933...7,440,611 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr  X:105,115,732...105,153,702
Ensembl chr  X:105,115,732...105,153,702 		JBrowse link
G HPX hemopexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr21:29,749,913...29,759,176
Ensembl chr21:29,719,589...29,759,046 		JBrowse link
G HRH2 histamine receptor H2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22926047 NCBI chr 4:37,333,843...37,407,146
Ensembl chr 4:37,275,852...37,386,072 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO protein:altered localization:liver (rat) RGD PMID:12376827 RGD:10059389 NCBI chr 5:11,292,219...11,296,851
Ensembl chr 5:11,292,262...11,296,797 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO RGD PMID:29091898 RGD:15090820 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO RGD PMID:31121248 RGD:14985250 NCBI chr 3:53,070,462...53,077,566
Ensembl chr 3:53,070,695...53,087,496 		JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32289347 NCBI chr16:25,319,035...25,375,085
Ensembl chr16:25,319,035...25,385,515 		JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12153990 PMID:21245496 PMID:30013034 RGD:14975100 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23639586 PMID:25226513 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
G IL11 interleukin 11 ISO CTD Direct Evidence: therapeutic CTD PMID:11421492 NCBI chr 1:102,311,960...102,319,102
Ensembl chr 1:102,316,105...102,318,653 		JBrowse link
G IL12B interleukin 12B ISO CTD Direct Evidence: therapeutic CTD PMID:36520315 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228 		JBrowse link
G IL17A interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19633216 PMID:24949944 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513 		JBrowse link
G IL18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19164858 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348 		JBrowse link
G IL1A interleukin 1 alpha ISO CTD Direct Evidence: therapeutic CTD PMID:8218930 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G IL1B interleukin 1 beta treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD		 PMID:19164858 PMID:23102243 PMID:28138970 PMID:29091898 PMID:29278859 More... RGD:13793380 RGD:14975281 RGD:15036799 RGD:15090820 RGD:7204421 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr10:40,967,532...41,003,659
Ensembl chr10:40,896,669...41,034,113 		JBrowse link
G IL22 interleukin 22 ISO CTD Direct Evidence: therapeutic CTD PMID:15122762 PMID:16212920 PMID:23375450 NCBI chr10:10,487,367...10,492,238
Ensembl chr10:10,487,262...10,492,371 		JBrowse link
G IL4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21094227 PMID:21735453 PMID:22107450 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G IL6 interleukin 6 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:7532385 PMID:15763341 PMID:29091898 RGD:15090820 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G IMMT inner membrane mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr17:38,927,508...38,964,522
Ensembl chr17:38,927,531...38,967,004 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:30515189 NCBI chr20:44,737,021...44,738,932
Ensembl chr20:44,736,832...44,763,020 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO RGD PMID:18417483 RGD:6893370 NCBI chr20:50,651,070...50,661,178
Ensembl chr20:50,650,711...50,658,496 		JBrowse link
G KITLG KIT ligand ISO CTD Direct Evidence: therapeutic CTD PMID:12594235 NCBI chr15:29,591,068...29,671,985
Ensembl chr15:29,591,170...29,671,974 		JBrowse link
G KNG1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20362651 PMID:30685357 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081 		JBrowse link
G KRT18 keratin 18 ISO mRNA, protein:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17340120 PMID:19783637 PMID:33483742 RGD:18337498 NCBI chr27:2,189,269...2,193,368
Ensembl chr27:2,189,269...2,193,368 		JBrowse link
G KRT8 keratin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr27:2,221,608...2,229,343 JBrowse link
G LAP3 leucine aminopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 3:62,898,626...62,924,738
Ensembl chr 3:62,898,699...62,924,727 		JBrowse link
G LBP lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr24:26,810,369...26,833,515
Ensembl chr24:26,809,843...26,833,434 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase ISO mRNA:decreased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chr 5:81,556,047...81,559,313 JBrowse link
G LCN2 lipocalin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20362651 PMID:20623750 NCBI chr 9:55,328,118...55,342,535
Ensembl chr 9:55,328,133...55,332,038 		JBrowse link
G LDLR low density lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:36108984 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355 		JBrowse link
G LGALS3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22461450 NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705 		JBrowse link
G LIPC lipase C, hepatic type ISO mRNA:decreased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chr30:23,432,460...23,584,037
Ensembl chr30:23,432,493...23,584,037 		JBrowse link
G LOC100855540 hemoglobin subunit alpha-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 6:40,324,378...40,325,427 JBrowse link
G LOC100855552 creatine kinase B-type ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 8:71,284,104...71,287,379 JBrowse link
G LOC477072 serotransferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845 		JBrowse link
G LOC479912 glutathione S-transferase Mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 6:42,201,697...42,207,886 JBrowse link
G LOC482182 sulfotransferase 1E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr13:59,323,430...59,343,745 JBrowse link
G LOC608697 2-hydroxyacyl-CoA lyase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr23:27,069,676...27,188,247 JBrowse link
G LOC610636 tubulin alpha-1B chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr37:25,811,491...25,818,838 JBrowse link
G LOC612036 solute carrier family 22 member 20-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr18:51,925,890...51,939,184 JBrowse link
G LPL lipoprotein lipase treatment ISO RGD PMID:27071702 RGD:13794380 NCBI chr25:37,078,306...37,102,729
Ensembl chr25:37,079,756...37,102,700 		JBrowse link
G LRAT lecithin retinol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr15:52,399,773...52,409,590
Ensembl chr15:52,399,544...52,406,176 		JBrowse link
G LTB4R leukotriene B4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28487374 NCBI chr 8:4,282,924...4,286,869
Ensembl chr 8:4,285,323...4,286,534 		JBrowse link
G LTF lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16141546 NCBI chr20:42,231,994...42,263,202
Ensembl chr20:42,231,994...42,263,202 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 5:65,669,553...65,683,445 JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18700144 NCBI chr 1:29,107,813...29,306,437
Ensembl chr 1:29,108,591...29,306,503 		JBrowse link
G MAT1A methionine adenosyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 4:29,450,857...29,467,251
Ensembl chr 4:29,452,601...29,466,929 		JBrowse link
G MCCC1 methylcrotonyl-CoA carboxylase subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr34:16,022,493...16,084,346
Ensembl chr34:16,022,499...16,084,387 		JBrowse link
G MDH1 malate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr10:63,316,818...63,334,556
Ensembl chr10:63,316,831...63,361,735 		JBrowse link
G ME1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr12:43,623,413...43,793,590
Ensembl chr12:43,624,945...43,828,775 		JBrowse link
G MED1 mediator complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16109766 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349 		JBrowse link
G MIR1-1 microRNA mir-1-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30125006 NCBI chr24:46,481,078...46,481,136
Ensembl chr24:46,481,078...46,481,136 		JBrowse link
G MIR103-1 microRNA mir-103-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 4:43,182,876...43,182,937
Ensembl chr 4:43,182,871...43,182,942 		JBrowse link
G MIR106B microRNA mir-106b ISO miRNA:decreased expression:liver (rat) RGD PMID:29554950 RGD:15042854 NCBI chr 6:9,498,558...9,498,616
Ensembl chr 6:9,498,558...9,498,616 		JBrowse link
G MIR107 microRNA mir-107 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr28:4,484,653...4,484,710
Ensembl chr28:4,484,646...4,484,718 		JBrowse link
G MIR10A microRNA mir-10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 9:24,842,171...24,842,233
Ensembl chr 9:24,842,145...24,842,248 		JBrowse link
G MIR10B microRNA mir-10b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr36:19,958,913...19,959,013
Ensembl chr36:19,958,913...19,959,013 		JBrowse link
G MIR122 microRNA mir-122 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22045675 PMID:22363424 PMID:25359176 PMID:25527335 PMID:26489516 More... NCBI chr 1:17,593,858...17,593,915
Ensembl chr 1:17,593,837...17,593,929 		JBrowse link
G MIR1249 microRNA mir-1249 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:20,818,801...20,818,939
Ensembl chr10:20,818,801...20,818,939 		JBrowse link
G MIR125B-1 microRNA mir-125b-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 5:12,097,672...12,097,732
Ensembl chr 5:12,097,658...12,097,745 		JBrowse link
G MIR125B-2 microRNA mir-125b-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr31:13,304,980...13,305,040
Ensembl chr31:13,304,964...13,305,052 		JBrowse link
G MIR1306 microRNA mir-1306 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr26:29,255,671...29,255,728
Ensembl chr26:29,255,656...29,255,735 		JBrowse link
G MIR1307 microRNA mir-1307 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr28:15,765,927...15,765,986
Ensembl chr28:15,765,918...15,765,997 		JBrowse link
G MIR130A microRNA mir-130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr18:38,543,618...38,543,679
Ensembl chr18:38,543,618...38,543,681 		JBrowse link
G MIR132 microRNA mir-132 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 9:46,153,531...46,153,590
Ensembl chr 9:46,153,511...46,153,611 		JBrowse link
G MIR142 microRNA mir-142 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 9:32,977,393...32,977,455
Ensembl chr 9:32,977,382...32,977,468 		JBrowse link
G MIR143 microRNA mir-143 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30125006 NCBI chr 4:59,534,535...59,534,589
Ensembl chr 4:59,534,535...59,534,594 		JBrowse link
G MIR148A microRNA mir-148a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr14:39,301,847...39,301,906
Ensembl chr14:39,301,843...39,301,920 		JBrowse link
G MIR150 microRNA mir-150 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:106,998,756...106,998,812
Ensembl chr 1:106,998,756...106,998,812 		JBrowse link
G MIR152 microRNA mir-152 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 9:24,335,161...24,335,219
Ensembl chr 9:24,335,146...24,335,225 		JBrowse link
G MIR155 microRNA mir-155 treatment ISO RGD PMID:26867493 PMID:27673475 PMID:29420849 RGD:21409750 RGD:25671463 RGD:25671474 NCBI chr31:21,078,768...21,078,828
Ensembl chr31:21,078,758...21,078,833 		JBrowse link
G MIR17 microRNA mir-17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr22:42,478,013...42,478,071
Ensembl chr22:42,478,000...42,478,083 		JBrowse link
G MIR181C microRNA mir-181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr20:48,593,343...48,593,403
Ensembl chr20:48,593,325...48,593,421 		JBrowse link
G MIR188 microRNA mir-188 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:42,775,058...42,775,143
Ensembl chr  X:42,775,058...42,775,143 		JBrowse link
G MIR18A microRNA mir-18a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr22:42,478,138...42,478,229
Ensembl chr22:42,478,138...42,478,229 		JBrowse link
G MIR191 microRNA mir-191 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr20:40,144,135...40,144,198
Ensembl chr20:40,144,121...40,144,210 		JBrowse link
G MIR192 microRNA mir-192 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22045675 PMID:25359176 PMID:28483554 PMID:28545106 NCBI chr18:52,281,129...52,281,193
Ensembl chr18:52,281,129...52,281,193 		JBrowse link
G MIR193A microRNA mir-193a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 9:41,316,481...41,316,536
Ensembl chr 9:41,316,474...41,316,542 		JBrowse link
G MIR193B microRNA mir-193b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 6:28,878,050...28,878,108
Ensembl chr 6:28,878,050...28,878,108 		JBrowse link
G MIR194 microRNA mir-194 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28844483 NCBI chr38:14,895,401...14,895,458
Ensembl chr38:14,895,401...14,895,458 		JBrowse link
G MIR19A microRNA mir-19a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr22:42,478,298...42,478,355
Ensembl chr22:42,478,285...42,478,366 		JBrowse link
G MIR200C microRNA mir-200c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr27:38,082,097...38,082,159
Ensembl chr27:38,082,091...38,082,169 		JBrowse link
G MIR203 microRNA mir-203 ISO CTD Direct Evidence: therapeutic CTD PMID:32659284 NCBI chr 8:71,774,247...71,774,340
Ensembl chr 8:71,774,247...71,774,340 		JBrowse link
G MIR21 microRNA mir-21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MIR217 microRNA mir-217 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr10:56,754,566...56,754,647
Ensembl chr10:56,754,566...56,754,647 		JBrowse link
G MIR218-1 microRNA mir-218-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 PMID:30125006 NCBI chr 3:89,044,709...89,044,772
Ensembl chr 3:89,044,699...89,044,782 		JBrowse link
G MIR22 microRNA mir-22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr 9:45,852,534...45,852,593
Ensembl chr 9:45,852,517...45,852,609 		JBrowse link
G MIR221 microRNA mir-221 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:39,523,890...39,523,951
Ensembl chr  X:39,523,885...39,523,954 		JBrowse link
G MIR222 microRNA mir-222 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:39,524,519...39,524,608
Ensembl chr  X:39,524,519...39,524,608 		JBrowse link
G MIR223 microRNA mir-223 ISO RNA:increased expression:serum,liver RGD PMID:28646120 RGD:21408574 NCBI chr  X:50,838,131...50,838,233
Ensembl chr  X:50,838,131...50,838,233 		JBrowse link
G MIR23A microRNA mir-23a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr20:48,620,335...48,620,386
Ensembl chr20:48,620,323...48,620,397 		JBrowse link
G MIR23B microRNA mir-23b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:71,678,353...71,678,406
Ensembl chr 1:71,678,346...71,678,416 		JBrowse link
G MIR27B microRNA mir-27b ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr 1:71,678,117...71,678,179
Ensembl chr 1:71,678,105...71,678,191 		JBrowse link
G MIR29B-2 microRNA mir-29b-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 7:6,651,878...6,651,943
Ensembl chr 7:6,651,866...6,651,955 		JBrowse link
G MIR29C-2 microRNA mir-29c-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 PMID:30515189 NCBI chr 7:6,651,339...6,651,396 JBrowse link
G MIR301A microRNA mir-301a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 9:33,724,572...33,724,655
Ensembl chr 9:33,724,571...33,724,655 		JBrowse link
G MIR30A microRNA mir-30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 PMID:25359176 PMID:28545106 NCBI chr12:33,783,894...33,783,956
Ensembl chr12:33,783,891...33,783,961 		JBrowse link
G MIR30B microRNA mir-30b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr13:30,906,038...30,906,097
Ensembl chr13:30,906,038...30,906,097 		JBrowse link
G MIR30C-1 microRNA mir-30c-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr15:2,280,050...2,280,110
Ensembl chr15:2,280,039...2,280,121 		JBrowse link
G MIR335 microRNA mir-335 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr14:6,444,861...6,444,918
Ensembl chr14:6,444,847...6,444,932 		JBrowse link
G MIR33B microRNA mir-33b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 5:41,685,165...41,685,258
Ensembl chr 5:41,685,165...41,685,258 		JBrowse link
G MIR342 microRNA mir-342 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 8:68,424,656...68,424,718 JBrowse link
G MIR345 microRNA mir-345 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 8:68,592,447...68,592,506 JBrowse link
G MIR34A microRNA mir-34a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 5:62,485,832...62,485,897
Ensembl chr 5:62,485,832...62,485,897 		JBrowse link
G MIR34C microRNA mir-34c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 5:21,558,106...21,558,160 JBrowse link
G MIR361 microRNA mir-361 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:66,698,698...66,698,760
Ensembl chr  X:66,698,698...66,698,760 		JBrowse link
G MIR367 microRNA mir-367 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr32:32,428,905...32,428,972
Ensembl chr32:32,428,905...32,428,972 		JBrowse link
G MIR378 microRNA mir-378 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 4:59,276,347...59,276,406
Ensembl chr 4:59,276,336...59,276,417 		JBrowse link
G MIR410 microRNA mir-410 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 8:69,294,377...69,294,432 JBrowse link
G MIR421 microRNA mir-421 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:57,550,055...57,550,110
Ensembl chr  X:57,550,039...57,550,123 		JBrowse link
G MIR423A microRNA mir-423a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 9:44,155,913...44,155,971 JBrowse link
G MIR452 microRNA mir-452 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:119,926,379...119,926,463
Ensembl chr  X:119,926,379...119,926,463 		JBrowse link
G MIR455 microRNA mir-455 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr11:68,461,911...68,461,968
Ensembl chr11:68,461,896...68,461,983 		JBrowse link
G MIR497 microRNA mir-497 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 5:32,045,759...32,045,825
Ensembl chr 5:32,045,759...32,045,825 		JBrowse link
G MIR505 microRNA mir-505 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:109,866,448...109,866,523
Ensembl chr  X:109,866,448...109,866,523 		JBrowse link
G MIR532 microRNA mir-532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:42,774,680...42,774,738
Ensembl chr  X:42,774,680...42,774,738 		JBrowse link
G MIR592 microRNA mir-592 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 PMID:28545106 NCBI chr14:9,182,237...9,182,331
Ensembl chr14:9,182,237...9,182,331 		JBrowse link
G MIR660 microRNA mir-660 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:42,783,965...42,784,023
Ensembl chr  X:42,783,965...42,784,023 		JBrowse link
G MIR885 microRNA mir-885 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr20:7,968,529...7,968,602
Ensembl chr20:7,968,529...7,968,602 		JBrowse link
G MIR93 microRNA mir-93 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 6:9,498,780...9,498,840 JBrowse link
G MIR99A-1 microRNA mir-99a-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr31:13,258,782...13,258,840
Ensembl chr31:13,258,782...13,258,840 		JBrowse link
G MIR99A-2 microRNA mir-99a-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 5:12,047,369...12,047,425
Ensembl chr 5:12,047,369...12,047,425 		JBrowse link
G MIRLET7C microRNA let-7c ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr31:13,259,522...13,259,588
Ensembl chr31:13,259,502...13,259,609 		JBrowse link
G MIRLET7D microRNA let-7d ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:97,902,012...97,902,136
Ensembl chr 1:97,902,012...97,902,136 		JBrowse link
G MIRLET7G microRNA let-7g ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr20:37,501,074...37,501,152
Ensembl chr20:37,501,054...37,501,160 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15763341 NCBI chr 2:60,471,092...60,492,991
Ensembl chr 2:60,471,257...60,494,113 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293 		JBrowse link
G MST1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr20:39,582,237...39,586,958
Ensembl chr20:39,582,282...39,586,908 		JBrowse link
G MST1R macrophage stimulating 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22575169 NCBI chr20:39,386,970...39,400,780
Ensembl chr20:39,387,322...39,400,588 		JBrowse link
G MT-ND6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 ISO mRNA:decreased expression:blood RGD PMID:20130021 RGD:8657129 NCBI chr MT:13,582...14,109
Ensembl chr MT:13,582...14,109 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase treatment ISO associated with precursor lymphoblastic lymphoma/leukemia; DNA:SNP: :677C>T(human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:18551038 PMID:19648163 PMID:30545275 RGD:14696733 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G MTPN myotrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr16:12,316,487...12,369,148
Ensembl chr16:12,316,336...12,369,387 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:17615358 RGD:150521532 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr18:42,069,402...42,075,843
Ensembl chr18:42,069,398...42,076,921 		JBrowse link
G NECAB3 N-terminal EF-hand calcium binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30515189 NCBI chr24:22,895,149...22,904,689
Ensembl chr24:22,878,402...22,904,656 		JBrowse link
G NFATC4 nuclear factor of activated T cells 4 ISO CTD Direct Evidence: therapeutic CTD PMID:34192554 NCBI chr 8:4,337,098...4,346,409
Ensembl chr 8:4,336,450...4,346,100 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO CTD Direct Evidence: therapeutic
induced by methotrexate (CHEBI:44185), treated by ferulic acid (CHEBI:17620)		 CTD
RGD		 PMID:18417483 PMID:22491424 PMID:22627062 PMID:24813929 PMID:26958860 More... RGD:15090820 RGD:21201280 RGD:21201283 RGD:21201305 RGD:21201308 RGD:6893370 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 treatment
susceptibility		 ISO associated with tuberculosis ;DNA:SNPs,haplotypes: 3'utr,5'utr: (rs78872571,rs4647992) (human) RGD PMID:29091898 PMID:31490979 RGD:15090820 RGD:40902984 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703 		JBrowse link
G NFXL1 nuclear transcription factor, X-box binding like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr13:43,743,271...43,814,899
Ensembl chr13:43,744,181...43,814,520 		JBrowse link
G NME2 non-metastatic cells 2, protein (NM23B) expressed in ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 9:27,002,114...27,005,740
Ensembl chr 9:27,001,733...27,015,934 		JBrowse link
G NOTCH1 notch receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:30394310 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G NOX4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO RGD PMID:28472605 PMID:28522909 PMID:29091898 RGD:13439737 RGD:13439739 RGD:15090820 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29943110 NCBI chr 2:73,234,482...73,236,548
Ensembl chr 2:73,234,586...73,236,206 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 treatment ISO RGD PMID:24497272 RGD:10448995 NCBI chr 9:22,461,556...22,469,243
Ensembl chr 9:22,461,705...22,469,053 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 ISO CTD Direct Evidence: therapeutic CTD PMID:17256725 NCBI chr18:42,333,173...42,346,152
Ensembl chr18:42,333,202...42,341,236 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 severity
treatment		 ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:liver (rat)
mRNA:decreased expression:liver (rat)		 CTD
RGD		 PMID:12875239 PMID:20573685 PMID:22711662 PMID:28827769 PMID:29091898 More... RGD:14701035 RGD:14701036 RGD:15042870 RGD:15045609 RGD:15090820 NCBI chr15:39,497,313...39,608,120
Ensembl chr15:39,536,290...39,608,116 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 susceptibility ISO CTD Direct Evidence: marker/mechanism|therapeutic
associated with tuberculosis ;DNA:SNP,haplotypes:promoter: (rs3814055) (human)		 CTD
RGD		 PMID:19797606 PMID:28058446 PMID:31490979 RGD:40902984 NCBI chr33:23,444,367...23,456,405
Ensembl chr33:23,432,690...23,455,347 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14742670 PMID:25656644 PMID:28058446 NCBI chr38:21,252,874...21,257,951
Ensembl chr38:21,253,089...21,258,827 		JBrowse link
G NR2F2 nuclear receptor subfamily 2 group F member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 3:44,135,143...44,148,836
Ensembl chr 3:44,136,463...44,148,524 		JBrowse link
G NR5A2 nuclear receptor subfamily 5 group A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29515023 NCBI chr 7:2,925,915...3,062,118
Ensembl chr 7:2,927,326...3,062,348 		JBrowse link
G NREP neuronal regeneration related protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 3:997,142...1,025,215
Ensembl chr 3:997,234...1,024,087 		JBrowse link
G NTN1 netrin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:35292334 NCBI chr 5:33,654,723...33,825,832
Ensembl chr 5:33,637,142...33,825,899 		JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO CTD Direct Evidence: therapeutic CTD PMID:33812996 NCBI chr 1:57,866,760...57,895,505
Ensembl chr 1:57,866,879...57,893,077 		JBrowse link
G OCIAD1 OCIA domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr13:44,608,474...44,634,665
Ensembl chr13:44,565,044...44,634,263 		JBrowse link
G OGDH oxoglutarate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249
G OR51E2 olfactory receptor family 51 subfamily E member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr21:27,078,888...27,081,746
Ensembl chr21:27,080,476...27,081,438 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 9:427,827...436,880
Ensembl chr 9:427,830...436,064 		JBrowse link
G PAH phenylalanine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr15:41,590,253...41,670,156
Ensembl chr15:41,592,876...41,670,837 		JBrowse link
G PAN2 poly(A) specific ribonuclease subunit PAN2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr10:621,286...636,899
Ensembl chr10:621,281...634,495 		JBrowse link
G PANX1 pannexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29246445 NCBI chr21:6,665,730...6,715,272
Ensembl chr21:6,668,269...6,715,858 		JBrowse link
G PARK7 Parkinsonism associated deglycase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PC pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr18:50,406,994...50,507,677
Ensembl chr18:50,412,272...50,507,669 		JBrowse link
G PCOLCE procollagen C-endopeptidase enhancer ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 6:9,085,145...9,090,447
Ensembl chr 6:9,085,145...9,090,146 		JBrowse link
G PCYT1A phosphate cytidylyltransferase 1A, choline ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr33:29,363,282...29,414,635
Ensembl chr33:29,358,452...29,430,424 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21182459 PMID:31809757 NCBI chr14:20,825,861...20,839,290
Ensembl chr14:20,827,831...20,839,256 		JBrowse link
G PDLIM5 PDZ and LIM domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr32:17,294,023...17,505,212
Ensembl chr32:17,294,073...17,502,409 		JBrowse link
G PEX11A peroxisomal biogenesis factor 11 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 3:52,674,363...52,684,776
Ensembl chr 3:52,674,348...52,684,660 		JBrowse link
G PGM1 phosphoglucomutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 5:46,444,433...46,577,621
Ensembl chr 5:46,515,295...46,577,622 		JBrowse link
G PLAT plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chr16:23,469,590...23,496,013 JBrowse link
G PLG plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G PLS3 plastin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr  X:88,308,817...88,399,682
Ensembl chr  X:88,308,888...88,398,810 		JBrowse link
G PNP purine nucleoside phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr15:17,808,454...17,815,987
Ensembl chr15:17,808,461...17,815,676 		JBrowse link
G PNRC1 proline rich nuclear receptor coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr12:48,339,946...48,344,026
Ensembl chr12:48,339,346...48,415,732 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit no_association
susceptibility		 ISO DNA:missense mutations:cds:p.Q1236H, p.E1143G (33708G>T, 3428A>G) (human)
DNA:missense mutation:cds:p.W748S, p.E1143G (2243G>C, 3428A>G) (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:18208989 PMID:20138553 PMID:25065347 PMID:30255931 RGD:15039297 RGD:15039302 NCBI chr 3:52,357,062...52,373,768
Ensembl chr 3:52,357,068...52,421,544 		JBrowse link
G POLR2G RNA polymerase II subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr18:53,916,431...53,919,724
Ensembl chr18:53,916,435...53,919,549 		JBrowse link
G PON1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr14:20,565,620...20,600,774
Ensembl chr14:20,565,641...20,642,985 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism
LPS-induced acute liver damage		 CTD
RGD		 PMID:21262334 PMID:24385052 RGD:5509941 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO mRNA, protein:decreased expression:liver RGD PMID:26599535 RGD:11554658 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G PPTC7 protein phosphatase targeting COQ7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr26:8,345,690...8,383,902
Ensembl chr26:8,349,453...8,383,617 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 treatment ISO RGD PMID:29091898 RGD:15090820 NCBI chr 4:68,579,061...68,614,548
Ensembl chr 4:68,579,037...68,611,841 		JBrowse link
G PRKCD protein kinase C delta ISO CTD Direct Evidence: therapeutic CTD PMID:30393195 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21224054 NCBI chr29:24,904...243,926
Ensembl chr29:35,007...243,895 		JBrowse link
G PTF1A pancreas associated transcription factor 1a ISO CTD Direct Evidence: therapeutic CTD PMID:21182459 NCBI chr 2:10,069,594...10,071,360
Ensembl chr 2:10,069,581...10,071,336 		JBrowse link
G PTGES2 prostaglandin E synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31444509 NCBI chr 9:55,343,424...55,349,349
Ensembl chr 9:55,343,424...55,348,959 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:11743745 PMID:29091898 RGD:15090820 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G PUM1 pumilio RNA binding family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:69,907,655...70,044,055
Ensembl chr 2:69,907,735...70,042,680 		JBrowse link
G PYGL glycogen phosphorylase L ISO protein:increased expression:serum (rat)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:25231249 PMID:25336395 RGD:21079733 NCBI chr 8:27,264,778...27,307,977
Ensembl chr 8:27,223,273...27,307,977 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 3:21,068,182...21,177,288
Ensembl chr 3:21,054,930...21,176,757 		JBrowse link
G RBP1 retinol binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr23:35,677,844...35,698,194
Ensembl chr23:35,679,176...35,698,363 		JBrowse link
G RDH13 retinol dehydrogenase 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27865848 NCBI chr 1:102,539,363...102,552,749
Ensembl chr 1:102,539,124...102,554,027 		JBrowse link
G REEP5 receptor accessory protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr 3:6,733...25,840
Ensembl chr 3:8,236...25,824 		JBrowse link
G RGN regucalcin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr  X:40,697,292...40,715,491
Ensembl chr  X:40,698,768...40,715,490 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 ISO CTD Direct Evidence: therapeutic
protein:increased expression:liver (mouse)		 CTD
RGD		 PMID:26769846 PMID:28205631 RGD:127229945 NCBI chr 8:4,304,167...4,309,514
Ensembl chr 8:4,305,250...4,309,325 		JBrowse link
G S100A11 S100 calcium binding protein A11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr17:61,020,136...61,050,513 JBrowse link
G SCARB1 scavenger receptor class B member 1 ISO mRNA:increased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chr26:5,035,797...5,122,383
Ensembl chr26:5,049,407...5,121,468 		JBrowse link
G SELENBP1 selenium binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr17:60,410,727...60,418,770
Ensembl chr17:60,410,734...60,418,704 		JBrowse link
G SEMA3A semaphorin 3A ISO CTD Direct Evidence: therapeutic CTD PMID:33290778 NCBI chr18:23,411,607...23,866,631
Ensembl chr18:23,414,576...23,867,098 		JBrowse link
G SEMA4A semaphorin 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:33290778 NCBI chr 7:41,670,814...41,695,349
Ensembl chr 7:41,672,120...41,692,460 		JBrowse link
G SENP2 SUMO specific peptidase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29535048 NCBI chr34:18,325,373...18,357,152
Ensembl chr34:18,325,553...18,356,192 		JBrowse link
G SERPINA1 serpin family A member 1 susceptibility ISO protein:decreased expression:plasma
DNA:missense mutation:cds:p.E264V(human)		 RGD PMID:11140575 PMID:20170533 RGD:14695048 RGD:1643168 NCBI chr 8:63,388,498...63,400,377
Ensembl chr 8:63,376,945...63,398,435 		JBrowse link
G SERPINA6 serpin family A member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 8:63,323,896...63,341,829
Ensembl chr 8:63,323,933...63,453,708 		JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO associated with precursor lymphoblastic lymphoma/leukemia;DNA:SNPs: :DNA:SNPs: :677C>T, 1298A>C(human) RGD PMID:23183238 RGD:14696750 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301 		JBrowse link
G SERPING1 serpin family G member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr18:38,570,354...38,580,751
Ensembl chr18:38,570,607...38,581,665 		JBrowse link
G SESN2 sestrin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:28209544 NCBI chr 2:72,151,464...72,168,861
Ensembl chr 2:72,151,868...72,168,492 		JBrowse link
G SGF29 SAGA complex associated factor 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 6:18,179,656...18,209,206
Ensembl chr 6:18,172,289...18,209,160 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 PMID:32659284 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G SLC10A1 solute carrier family 10 member 1 ISO mRNA:decreased expression:liver (rat) RGD PMID:28827769 RGD:15045609 NCBI chr 8:43,521,291...43,546,426
Ensembl chr 8:43,521,747...43,546,274 		JBrowse link
G SLC10A7 solute carrier family 10 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr15:44,718,085...44,957,787
Ensembl chr15:44,720,629...44,957,495 		JBrowse link
G SLC13A4 solute carrier family 13 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr16:12,539,369...12,581,155
Ensembl chr16:12,540,263...12,579,949 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr18:53,709,592...53,728,595
Ensembl chr18:53,709,591...53,728,578 		JBrowse link
G SLC25A29 solute carrier family 25 member 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 8:68,578,323...68,585,867
Ensembl chr 8:68,566,924...68,585,545 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 treatment ISO RGD PMID:9200186 RGD:151357001 NCBI chr 5:65,313,105...65,343,858
Ensembl chr 5:65,313,105...65,343,858 		JBrowse link
G SLPI secretory leukocyte peptidase inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr24:32,566,030...32,568,406
Ensembl chr24:32,566,026...32,568,420 		JBrowse link
G SNX18 sorting nexin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr 4:60,803,245...60,945,317
Ensembl chr 4:60,835,783...60,945,828 		JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 PMID:27349771 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SOD2 superoxide dismutase 2 treatment
susceptibility
severity		 ISO associated with acute lymphoblastic leukemia;DNA:SNP: :(rs4880)(human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:cds:p.Val16Ala(human)		 RGD
CTD		 PMID:19332662 PMID:19647030 PMID:20578157 PMID:25226513 PMID:27019981 RGD:11060605 RGD:26923957 RGD:26923959 RGD:26923961 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G SOD3 superoxide dismutase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:11529661 NCBI chr 3:85,382,698...85,387,144
Ensembl chr 3:85,382,484...85,387,455 		JBrowse link
G SORD sorbitol dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12763371 NCBI chr30:11,467,259...11,501,166
Ensembl chr30:11,467,253...11,500,641 		JBrowse link
G SORL1 sortilin related receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr 5:12,493,750...12,650,530
Ensembl chr 5:12,431,377...12,650,784 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr32:11,354,070...11,362,325
Ensembl chr32:11,353,953...11,362,069 		JBrowse link
G SRP72 signal recognition particle 72 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr13:48,688,295...48,717,826
Ensembl chr13:48,688,295...48,717,824 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 severity ISO mRNA:increased expression:liver, macrophage (mouse)
protein:increased phosphorylation:liver, inflammatory cell (mouse)		 RGD PMID:23876342 PMID:24731448 RGD:25671417 RGD:25671422 NCBI chr37:1,566,563...1,685,378
Ensembl chr37:1,566,585...1,829,894 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:36520315 NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072 		JBrowse link
G SULT1C3 sulfotransferase family 1C member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr10:35,610,282...35,644,315
Ensembl chr10:35,610,989...35,644,557 		JBrowse link
G SULT2B1 sulfotransferase family 2B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27052460 NCBI chr 1:107,705,568...107,721,160
Ensembl chr 1:107,705,576...107,720,876 		JBrowse link
G SUOX sulfite oxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr10:327,656...331,826
Ensembl chr10:327,671...331,825 		JBrowse link
G TAGLN2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr38:22,224,223...22,230,292
Ensembl chr38:22,225,133...22,229,766 		JBrowse link
G TALDO1 transaldolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19436114 NCBI chr18:25,764,138...25,772,043 JBrowse link
G TBXA2R thromboxane A2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22206755 NCBI chr20:55,819,866...55,829,395
Ensembl chr20:55,824,410...55,828,980 		JBrowse link
G TCTN1 tectonic family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr26:8,411,429...8,444,640
Ensembl chr26:8,407,105...8,437,027 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28560358 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594 		JBrowse link
G THBS1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35357534 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915 		JBrowse link
G THPO thrombopoietin ISO CTD Direct Evidence: therapeutic CTD PMID:33122006 NCBI chr34:17,245,006...17,255,250
Ensembl chr34:17,247,731...17,253,033 		JBrowse link
G TLR4 toll like receptor 4 disease_progression ISO RGD PMID:17504260 RGD:14697733 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TLR5 toll like receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30508503 NCBI chr38:23,700,323...23,705,628
Ensembl chr38:23,702,033...23,705,314 		JBrowse link
G TLR9 toll like receptor 9 severity
treatment		 ISO protein:increased expression: blood, neutrophil (human) RGD PMID:19164858 PMID:23509352 PMID:26457748 RGD:18337465 RGD:18337473 RGD:18337476 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G TMED7 transmembrane p24 trafficking protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr11:5,342,265...5,356,828
Ensembl chr11:5,342,265...5,356,828 		JBrowse link
G TMEM117 transmembrane protein 117 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr27:9,782,805...10,246,635
Ensembl chr27:9,782,805...10,235,028 		JBrowse link
G TMEM164 transmembrane protein 164 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr  X:83,219,530...83,384,900
Ensembl chr  X:83,219,505...83,381,564 		JBrowse link
G TMEM38B transmembrane protein 38B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr11:61,511,756...61,561,987
Ensembl chr11:61,511,750...61,560,556 		JBrowse link
G TNF tumor necrosis factor treatment
severity		 ISO protein:increased expression:serum (rat)
CTD Direct Evidence: marker/mechanism|therapeutic		 RGD
CTD		 PMID:7532385 PMID:9309314 PMID:9696492 PMID:10801287 PMID:10801288 More... RGD:10450531 RGD:14696804 RGD:14975281 RGD:14995429 RGD:14995432 RGD:14995435 RGD:14995437 RGD:14995485 RGD:15036799 RGD:15090820 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 ISO RGD PMID:24569808 RGD:9999438 NCBI chr31:38,201,075...38,224,076 JBrowse link
G TTR transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 7:57,940,354...57,947,084
Ensembl chr 7:57,914,381...57,947,058 		JBrowse link
G TUBB4B tubulin beta 4B class IVb ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 9:48,432,114...48,434,626
Ensembl chr 9:48,427,766...48,571,640 		JBrowse link
G UBA5 ubiquitin like modifier activating enzyme 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr23:29,645,755...29,658,587
Ensembl chr23:29,645,966...29,659,019 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr18:49,826,044...49,835,417
Ensembl chr18:49,826,026...49,882,461 		JBrowse link
G USP5 ubiquitin specific peptidase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr27:38,158,850...38,172,689
Ensembl chr27:38,158,834...38,172,071 		JBrowse link
G VEGFA vascular endothelial growth factor A treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17784864 PMID:25231249 RGD:15003197 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965 		JBrowse link
G VIM vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 2:19,671,316...19,679,367
Ensembl chr 2:19,671,316...19,679,466 		JBrowse link
G VWF von Willebrand factor ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:liver:		 CTD
RGD		 PMID:7531171 PMID:28527913 RGD:11079232 NCBI chr27:38,834,812...38,972,614
Ensembl chr27:38,833,837...39,320,142 		JBrowse link
G WASL WASP like actin nucleation promoting factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr14:11,828,298...11,901,190
Ensembl chr14:11,828,687...11,899,788 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility ISO DNA:haploinsufficiency: : (mouse) RGD PMID:21737425 RGD:15036796 NCBI chr 1:111,548,719...111,571,816
Ensembl chr 1:111,548,719...111,571,816 		JBrowse link
G XYLB xylulokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr23:8,123,041...8,171,803
Ensembl chr23:8,122,197...8,170,447 		JBrowse link
G ZDHHC23 zinc finger DHHC-type palmitoyltransferase 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr33:18,215,822...18,227,626
Ensembl chr33:18,215,678...18,223,268 		JBrowse link
drug-induced hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 susceptibility
no_association		 ISO DNA:polymorphisms,haplotype:promoter:g.-1774delG,g.-1549G>A(human)
DNA:SNPs:multiple:		 RGD PMID:17502832 PMID:22178260 RGD:14700816 RGD:14700817 NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO DNA:hypermethylation:promoter RGD PMID:23619520 RGD:14700910 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:16140414 RGD:2316848 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294 		JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 ISO protein:increased expression:liver (mouse) RGD PMID:12201952 RGD:10054288 NCBI chr11:65,690,806...65,822,166
Ensembl chr11:65,692,973...65,822,312 		JBrowse link
G MIR22 microRNA mir-22 ISO in male; RNA:increased expression:liver: RGD PMID:21750200 RGD:14700876 NCBI chr 9:45,852,534...45,852,593
Ensembl chr 9:45,852,517...45,852,609 		JBrowse link
Halothane Hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPT glutamic--pyruvic transaminase treatment ISO RGD PMID:28921207 RGD:14975164 NCBI chr13:37,923,757...37,927,843
Ensembl chr13:37,924,422...37,926,156 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15603
    Chemically-Induced Disorders 1268
      Poisoning 711
        Chemical and Drug Induced Liver Injury 426
          Halothane Hepatitis 1
          drug-induced hepatitis 5
Path 2
Term Annotations click to browse term
  disease 15603
    disease of anatomical entity 15182
      gastrointestinal system disease 6540
        hepatobiliary disease 2901
          liver disease 2799
            Liver Injury 507
              Chemical and Drug Induced Liver Injury 426
                Halothane Hepatitis 1
                drug-induced hepatitis 5
paths to the root