MIR194 (microRNA mir-194) - Rat Genome Database

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Gene: MIR194 (microRNA mir-194) Canis lupus familiaris
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Symbol: MIR194 (Ensembl: MIR194-1)
Name: microRNA mir-194 (Ensembl:microRNA 194-1)
RGD ID: 12136717
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-194; microRNA 194
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13814,895,401 - 14,895,458 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3814,895,401 - 14,895,458 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3814,938,022 - 14,938,079 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03814,930,881 - 14,930,938 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3814,930,881 - 14,930,938 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.03815,286,924 - 15,286,981 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03815,575,390 - 15,575,447 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:18392026   PMID:38241360  


Genomics

Comparative Map Data
MIR194
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13814,895,401 - 14,895,458 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3814,895,401 - 14,895,458 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3814,938,022 - 14,938,079 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03814,930,881 - 14,930,938 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3814,930,881 - 14,930,938 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.03815,286,924 - 15,286,981 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03815,575,390 - 15,575,447 (-)NCBIUU_Cfam_GSD_1.0
MIR194-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381220,118,157 - 220,118,241 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1220,118,157 - 220,118,241 (-)EnsemblGRCh38hg38GRCh38
GRCh371220,291,499 - 220,291,583 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,358,121 - 218,358,205 (-)NCBINCBI36Build 36hg18NCBI36
Celera1193,510,708 - 193,510,792 (-)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1190,965,852 - 190,965,936 (-)NCBIHuRef
CHM1_11221,563,984 - 221,564,068 (-)NCBICHM1_1
T2T-CHM13v2.01219,357,431 - 219,357,515 (-)NCBIT2T-CHM13v2.0
Mir194-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391185,045,516 - 185,045,582 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1185,045,516 - 185,045,582 (+)EnsemblGRCm39 Ensembl
GRCm381185,313,319 - 185,313,385 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1185,313,319 - 185,313,385 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,137,198 - 187,137,264 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Cytogenetic Map1H5NCBI
cM Map189.49NCBI
Mir194-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81399,382,716 - 99,382,798 (+)NCBIGRCr8
mRatBN7.21396,851,166 - 96,851,248 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,851,166 - 96,851,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1399,350,308 - 99,350,390 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013100,756,265 - 100,756,347 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01397,932,562 - 97,932,644 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013103,250,576 - 103,250,658 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13103,250,576 - 103,250,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013107,924,394 - 107,924,476 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1396,366,365 - 96,366,447 (+)NCBICelera
Cytogenetic Map13q26NCBI
MIR194B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl109,704,910 - 9,704,987 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1109,704,910 - 9,704,987 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21011,786,871 - 11,786,948 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system reproductive system respiratory system
High
Medium
Low 1 4 2 1
Below cutoff 1 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000032678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3814,895,401 - 14,895,458 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845051132
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3814,930,881 - 14,930,938 (-)Ensembl
RefSeq Acc Id: NR_049318
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13814,895,401 - 14,895,458 (-)NCBI
Dog10K_Boxer_Tasha3814,938,022 - 14,938,079 (-)NCBI
ROS_Cfam_1.03814,930,881 - 14,930,938 (-)NCBI
UNSW_CanFamBas_1.03815,286,924 - 15,286,981 (-)NCBI
UU_Cfam_GSD_1.03815,575,390 - 15,575,447 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020571 Ensembl
  ENSCAFG00845028941 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00845051132 ENTREZGENE
miRBase MI0008091 ENTREZGENE
NCBI Gene MIR194 ENTREZGENE
RNAcentral URS000029C2DC RNACentral
  URS00007E35B8 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR194  microRNA mir-194    microRNA 194  Symbol and/or name change 5135510 APPROVED