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Gene: MIR188 (microRNA mir-188) Canis lupus familiaris
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Symbol: MIR188
Name: microRNA mir-188
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: cfa-mir-188; microRNA 188
Orthologs:
Homo sapiens (human) : MIR188 (microRNA 188)  HGNC  Alliance
Mus musculus (house mouse) : Mir188 (microRNA 188)  MGI
Rattus norvegicus (Norway rat) : Mir188 (microRNA 188)  Alliance
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,775,058 - 42,775,143 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog CytomapX NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences

Additional Information

External Database Links
Nomenclature History
 
More on MIR188
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12351798
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.