ADIPOQ (adiponectin, C1Q and collagen domain containing)

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Gene: ADIPOQ (adiponectin, C1Q and collagen domain containing) Canis lupus familiaris

Analyze

Symbol:

ADIPOQ

Name:

adiponectin, C1Q and collagen domain containing

RGD ID:

12420162

Description:

ENCODES a protein that exhibits hormone activity (ortholog); identical protein binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN brown fat cell differentiation (ortholog); cellular response to cAMP (ortholog); cellular response to epinephrine stimulus (ortholog); PARTICIPATES IN adiponectin signaling pathway; ASSOCIATED WITH 3MC syndrome 1 (ortholog); Acute Lung Injury (ortholog); Alcoholic Fatty Liver (ortholog); FOUND IN cell periphery (ortholog); cell surface (ortholog); endoplasmic reticulum (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ACDC; adipocyte, C1Q and collagen domain containing; adiponectin; APM1

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	19,398,310 - 19,410,519 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	19,354,825 - 19,409,844 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	23,492,088 - 23,493,907 (+)	NCBI
ROS_Cfam_1.0	34	19,309,590 - 19,321,861 (+)	NCBI
ROS_Cfam_1.0 Ensembl	34	19,309,535 - 19,321,387 (+)	Ensembl
UMICH_Zoey_3.1	34	19,349,075 - 19,350,894 (+)	NCBI
UNSW_CanFamBas_1.0	34	19,348,981 - 19,350,799 (+)	NCBI
UU_Cfam_GSD_1.0	34	19,582,218 - 19,584,037 (+)	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3MC syndrome 1 (ISO)

Acute Lung Injury (ISO)

Alcoholic Fatty Liver (ISO)

Alzheimer's disease (ISO)

amyloidosis (ISO)

ankylosing spondylitis (ISO)

asthma (ISO)

atherosclerosis (ISO)

autoimmune hepatitis (ISO)

Behcet's disease (ISO)

biliary atresia (ISO)

bipolar disorder (ISO)

brain infarction (ISO)

breast cancer (ISO)

cardiomyopathy (ISO)

cardiovascular system disease (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Choroidal Neovascularization (ISO)

Chronic Hepatitis C (ISO)

chronic obstructive pulmonary disease (ISO)

Cognitive Dysfunction (ISO)

colitis (ISO)

congestive heart failure (ISO)

coronary aneurysm (ISO)

coronary artery disease (ISO)

Coronary Disease (ISO)

coronary restenosis (ISO)

Crohn's disease (ISO)

dementia (ISO)

diabetes mellitus (ISO)

Diabetic Cardiomyopathies (ISO)

Diabetic Foot (ISO)

Diabetic Nephropathies (ISO)

diabetic retinopathy (ISO)

diffuse scleroderma (ISO)

dry eye syndrome (ISO)

end stage renal disease (ISO)

Endotoxemia (ISO)

Experimental Arthritis (ISO)

Experimental Autoimmune Myocarditis (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Cirrhosis (ISO)

familial hyperlipidemia (ISO)

familial Mediterranean fever (ISO)

fatty liver disease (ISO)

Fetal Growth Retardation (ISO)

gestational diabetes (ISO)

Graft vs Host Disease (ISO)

Graves' disease (ISO)

hepatocellular carcinoma (ISO)

heroin dependence (ISO)

HIV-Associated Lipodystrophy Syndrome (ISO)

Human Viral Hepatitis (ISO)

Huntington's disease (ISO)

Hyperemia (ISO)

hyperglycemia (ISO)

hyperinsulinism (ISO)

hypertension (ISO)

hyperthyroidism (ISO)

Hypertriglyceridemia (ISO)

Hypoadiponectinemia (ISO)

Inflammation (ISO)

inflammatory bowel disease (ISO)

Insulin Resistance (ISO)

Jaundice (ISO)

Kawasaki disease (ISO)

Kidney Reperfusion Injury (ISO)

Left Ventricular Hypertrophy (ISO)

liver cirrhosis (ISO)

Liver Reperfusion Injury (ISO)

Mammary Neoplasms, Experimental (ISO)

Masked Hypertension (ISO)

Metabolic Syndrome (ISO)

multiple sclerosis (ISO)

Mycobacterium avium complex disease (ISO)

myocardial infarction (ISO)

Myocardial Ischemia (ISO)

Myocardial Reperfusion Injury (ISO)

myocarditis (ISO)

non-alcoholic fatty liver disease (ISO)

obesity (ISO)

Oxygen-Induced Retinopathy (ISO)

Perennial Allergic Rhinitis (ISO)

peripheral artery disease (ISO)

polycystic ovary syndrome (ISO)

primary open angle glaucoma (ISO)

proliferative diabetic retinopathy (ISO)

prostate adenocarcinoma (ISO)

pulmonary edema (ISO)

pulmonary emphysema (ISO)

pulmonary fibrosis (ISO)

pulmonary hypertension (ISO)

pulmonary tuberculosis (ISO)

renal cell carcinoma (ISO)

Reperfusion Injury (ISO)

Rett syndrome (ISO)

rheumatoid arthritis (ISO)

Sepsis (ISO)

sleep apnea (ISO)

Spinal Cord Injuries (ISO)

Stroke (ISO)

Subarachnoid Hemorrhage (ISO)

systemic lupus erythematosus (ISO)

tongue squamous cell carcinoma (ISO)

type 1 diabetes mellitus (ISO)

type 2 diabetes mellitus (ISO)

ulcerative colitis (ISO)

vascular disease (ISO)

visual epilepsy (ISO)

Weight Gain (ISO)

Weight Loss (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

brown fat cell differentiation (IEA,ISO,ISS)

cellular response to cAMP (ISO)

cellular response to epinephrine stimulus (ISO)

cellular response to insulin stimulus (IEA,ISO,ISS)

cellular response to xenobiotic stimulus (IEA,ISS)

circadian rhythm (ISO)

detection of oxidative stress (IEA,ISS)

fatty acid beta-oxidation (IEA,ISO,ISS)

fatty acid oxidation (IEA,ISO,ISS)

gene expression (IEA,ISO)

glucose homeostasis (IEA,ISO,ISS)

glucose metabolic process (IEA,ISO,ISS)

low-density lipoprotein particle clearance (IEA,ISS)

negative regulation of blood pressure (IEA,ISS)

negative regulation of cell migration (IEA,ISS)

negative regulation of cold-induced thermogenesis (IEA)

negative regulation of DNA biosynthetic process (IEA,ISS)

negative regulation of ERK1 and ERK2 cascade (IEA,ISS)

negative regulation of fat cell differentiation (IEA,ISS)

negative regulation of gluconeogenesis (IEA,ISO,ISS)

negative regulation of granulocyte differentiation (IEA,ISS)

negative regulation of heterotypic cell-cell adhesion (IEA,ISS)

negative regulation of hormone secretion (ISO)

negative regulation of I-kappaB kinase/NF-kappaB signaling (IEA,ISS)

negative regulation of inflammatory response (IEA,ISS)

negative regulation of intracellular protein transport (IEA,ISS)

negative regulation of low-density lipoprotein receptor activity (IEA,ISO)

negative regulation of macrophage derived foam cell differentiation (IEA,ISS)

negative regulation of macrophage differentiation (IEA,ISS)

negative regulation of MAP kinase activity (IEA,ISS)

negative regulation of metanephric mesenchymal cell migration (IEA,ISS)

negative regulation of phagocytosis (IEA,ISS)

negative regulation of platelet-derived growth factor receptor signaling pathway (IEA,ISS)

negative regulation of platelet-derived growth factor receptor-alpha signaling pathway (IEA,ISS)

negative regulation of protein autophosphorylation (IEA,ISS)

negative regulation of receptor binding (IEA,ISS)

negative regulation of synaptic transmission (IEA,ISS)

negative regulation of transcription, DNA-templated (IEA,ISS)

negative regulation of tumor necrosis factor production (IEA,ISS)

negative regulation of tumor necrosis factor-mediated signaling pathway (IEA,ISS)

negative regulation of vascular associated smooth muscle cell migration (IEA,ISS)

negative regulation of vascular associated smooth muscle cell proliferation (IEA,ISS)

positive regulation of cAMP-dependent protein kinase activity (IEA,ISS)

positive regulation of cholesterol efflux (IEA,ISS)

positive regulation of cold-induced thermogenesis (IEA)

positive regulation of fatty acid metabolic process (IEA,ISO,ISS)

positive regulation of glucose import (IEA,ISO,ISS)

positive regulation of glycogen (starch) synthase activity (ISS)

positive regulation of I-kappaB kinase/NF-kappaB signaling (IEA,ISO,ISS)

positive regulation of interleukin-8 production (IEA,ISS)

positive regulation of lipid transporter activity (IEA,ISS)

positive regulation of metanephric podocyte development (IEA,ISS)

positive regulation of monocyte chemotactic protein-1 production (IEA,ISS)

positive regulation of myeloid cell apoptotic process (IEA,ISS)

positive regulation of peptidyl-tyrosine phosphorylation (ISO)

positive regulation of protein kinase A signaling (IEA,ISS)

positive regulation of protein kinase activity (ISO)

positive regulation of protein phosphorylation (IEA,ISS)

positive regulation of renal albumin absorption (IEA,ISS)

positive regulation of signal transduction (IEA,ISO,ISS)

protein localization to plasma membrane (IEA,ISS)

regulation of glucose metabolic process (IEA,ISS)

response to activity (ISO)

response to bacterium (IEA,ISO)

response to ethanol (ISO)

response to glucocorticoid (ISO)

response to glucose (IEA,ISO,ISS)

response to hypoxia (ISO)

response to linoleic acid (ISO)

response to nutrient (ISO)

response to nutrient levels (ISO)

response to sucrose (ISO)

response to tumor necrosis factor (IEA,ISS)

response to xenobiotic stimulus (ISO)

signal transduction (IEA)

translation (IEA)

translational initiation (IEA)

Cellular Component

cell periphery (ISS)

cell surface (IEA,ISS)

endoplasmic reticulum (IEA,ISS)

extracellular region (IEA)

extracellular space (IEA,ISO,ISS)

perinuclear region of cytoplasm (ISS)

protein-containing complex (ISO)

Molecular Function

ATP binding (IEA)

ATP hydrolysis activity (IEA)

helicase activity (IEA)

hormone activity (IEA,ISS)

hydrolase activity (IEA)

identical protein binding (IEA,ISO)

nucleic acid binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein homodimerization activity (IEA)

RNA helicase activity (IEA)

sialic acid binding (IEA)

signaling receptor binding (IEA,ISS)

translation initiation factor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

adiponectin signaling pathway (ISO)

References

Additional References at PubMed

PMID:16051287	PMID:21474268	PMID:21645805	PMID:22381588	PMID:24886049	PMID:25555336

Genomics

Comparative Map Data

ADIPOQ
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	19,398,310 - 19,410,519 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	19,354,825 - 19,409,844 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	23,492,088 - 23,493,907 (+)	NCBI
ROS_Cfam_1.0	34	19,309,590 - 19,321,861 (+)	NCBI
ROS_Cfam_1.0 Ensembl	34	19,309,535 - 19,321,387 (+)	Ensembl
UMICH_Zoey_3.1	34	19,349,075 - 19,350,894 (+)	NCBI
UNSW_CanFamBas_1.0	34	19,348,981 - 19,350,799 (+)	NCBI
UU_Cfam_GSD_1.0	34	19,582,218 - 19,584,037 (+)	NCBI

ADIPOQ
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	186,842,710 - 186,858,463 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	3	186,842,704 - 186,858,463 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	186,560,499 - 186,576,252 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	188,043,157 - 188,058,946 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	3	188,043,164 - 188,058,952	NCBI
Celera	3	184,996,682 - 185,012,474 (+)	NCBI
Cytogenetic Map	3	q27.3	NCBI
HuRef	3	183,969,546 - 183,985,186 (+)	NCBI		HuRef
CHM1_1	3	186,523,992 - 186,539,778 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	189,664,780 - 189,680,531 (+)	NCBI

Adipoq
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	22,965,286 - 22,976,718 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	16	22,965,286 - 22,976,778 (+)	Ensembl
GRCm38	16	23,146,536 - 23,157,968 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	23,146,536 - 23,158,028 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	23,146,609 - 23,158,041 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	16	23,061,870 - 23,073,302 (+)	NCBI			mm8
Celera	16	23,704,853 - 23,716,285 (+)	NCBI		Celera
Cytogenetic Map	16	B1	NCBI
cM Map	16	13.96	NCBI

Adipoq
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	11	77,721,912 - 77,735,644 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	11	77,721,912 - 77,735,564 (-)	Ensembl
Rnor_6.0	11	81,330,845 - 81,344,488 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	81,330,293 - 81,344,488 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	84,363,940 - 84,382,663 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	79,908,291 - 79,911,065 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	11	79,965,888 - 79,968,654 (-)	NCBI
Celera	11	76,596,543 - 76,599,824 (-)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

Adipoq
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	20,912,348 - 20,914,402 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	20,911,181 - 20,922,992 (-)	NCBI	ChiLan1.0	ChiLan1.0

ADIPOQ
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	192,341,471 - 192,354,885 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	192,341,320 - 192,354,885 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	183,876,051 - 183,889,723 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

Adipoq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	117,076,470 - 117,087,548 (-)	NCBI
SpeTri2.0	NW_004936578	3,168,599 - 3,179,369 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADIPOQ
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	124,633,684 - 124,646,648 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	124,633,906 - 124,646,237 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	134,076,753 - 134,077,342 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADIPOQ
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	81,128,427 - 81,142,779 (+)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	15	81,129,795 - 81,147,391 (+)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666041	54,621,772 - 54,634,568 (+)	NCBI	Vero_WHO_p1.0

Adipoq
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	69,941,001 - 69,957,012 (-)	Ensembl	HetGla_female_1.0		hetGla2
HetGla 1.0	NW_004624730	69,941,963 - 69,959,266 (-)	NCBI	HetGla_female_1.0		hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High			1						1
Medium	5	5	21	6	6	6	6	6	11	8	10	6
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001006644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005639713	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005639714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022414066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022414067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038445378	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038445379	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038445380	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038445381	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB110099	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF417206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GM710013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCAFT00845038706 ⟹ ENSCAFP00845030307

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	34	19,309,535 - 19,321,387 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845038743 ⟹ ENSCAFP00845030338

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	34	19,309,710 - 19,319,881 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845038776 ⟹ ENSCAFP00845030363

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	34	19,310,621 - 19,319,881 (+)	Ensembl

RefSeq Acc Id:

NM_001006644 ⟹ NP_001006645

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	34	19,406,611 - 19,408,430 (+)	NCBI
Dog10K_Boxer_Tasha	34	23,492,088 - 23,493,907 (+)	NCBI
ROS_Cfam_1.0	34	19,317,941 - 19,319,760 (+)	NCBI
UMICH_Zoey_3.1	34	19,349,075 - 19,350,894 (+)	NCBI
UNSW_CanFamBas_1.0	34	19,348,981 - 19,350,799 (+)	NCBI
UU_Cfam_GSD_1.0	34	19,582,218 - 19,584,037 (+)	NCBI

Sequence:

show sequence

ATGCTGTTGCTACGAGCTGTTCTACTGCTACTAGTCCTGCCCGCTCACGGCCAGGACTCCGTGG
CAGAAGGGCCTGGAGTCCTGCTTCCCCTGCCGAAAGGGGCCTGCCCAGGTTGGATGGCAGGCAT
CCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGAGAA
AAGGGAGAGAAAGGAGATGCAGGTCTTGTTGGTCCTAAGGGTGACACTGGTGAAACTGGAGTAA
CTGGGGTTGAAGGTCCCCGAGGCTTTCCAGGAACCCCATGCAGGAAAGGAGAACCTGGGGAAAG
TGCCTATGTACACCGTTCGGCATTCAGTGTGGGGTTGGAGAGCCGGATCACTGTCCCCAATGTT
CCCATTCGCTTTACCAAAATCTTCTACAATCTGCAAAACCACTACGATGGCACCACTGGAAAAT
TTCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGT
CAAGGTCAGCCTCTACAAGAAAGACAAGGCTATGCTCTTCACCTATGACCAGTACCAGGAGAAG
AACGTGGACCAGGCCTCTGGCTCTGTGCTCCTTCATCTGGAAGTGGGCGACCAAGTCTGGCTCC
AGGTGTACGGGGATGGGGACTCCTATGGGATCTACGCAGATAACGTCAATGACTCCACCTTTAC
GGGCTTCCTTCTCTACCATGACACCAACTGA

hide sequence

RefSeq Acc Id:

XM_038445378 ⟹ XP_038301306

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	34	19,309,626 - 19,321,861 (+)	NCBI

RefSeq Acc Id:

XM_038445379 ⟹ XP_038301307

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	34	19,309,590 - 19,321,861 (+)	NCBI

RefSeq Acc Id:

XM_038445380 ⟹ XP_038301308

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	34	19,310,585 - 19,321,861 (+)	NCBI

RefSeq Acc Id:

XM_038445381 ⟹ XP_038301309

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	34	19,310,615 - 19,321,861 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001006645	(Get FASTA)	NCBI Sequence Viewer
	XP_038301306	(Get FASTA)	NCBI Sequence Viewer
	XP_038301307	(Get FASTA)	NCBI Sequence Viewer
	XP_038301308	(Get FASTA)	NCBI Sequence Viewer
	XP_038301309	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL09702	(Get FASTA)	NCBI Sequence Viewer
	BAD15362	(Get FASTA)	NCBI Sequence Viewer
	CAT82847	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001006645 ⟸ NM_001006644
- Peptide Label:	precursor
- UniProtKB:	Q76C76 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLLRAVLLLLVLPAHGQDSVAEGPGVLLPLPKGACPGWMAGIPGHPGHNGTPGRDGRDGTPGE KGEKGDAGLVGPKGDTGETGVTGVEGPRGFPGTPCRKGEPGESAYVHRSAFSVGLESRITVPNV PIRFTKIFYNLQNHYDGTTGKFHCNIPGLYYFSYHITVYLKDVKVSLYKKDKAMLFTYDQYQEK NVDQASGSVLLHLEVGDQVWLQVYGDGDSYGIYADNVNDSTFTGFLLYHDTN hide sequence

RefSeq Acc Id:	XP_038301307 ⟸ XM_038445379
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038301306 ⟸ XM_038445378
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038301308 ⟸ XM_038445380
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038301309 ⟸ XM_038445381
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSCAFP00845030307 ⟸ ENSCAFT00845038706

RefSeq Acc Id:

ENSCAFP00845030363 ⟸ ENSCAFT00845038776

RefSeq Acc Id:

ENSCAFP00845030338 ⟸ ENSCAFT00845038743

Protein Domains

C1q Helicase ATP-binding Helicase C-terminal Q_MOTIF

Promoters

RGD ID:

13688913

Promoter ID:

EPDNEW_C6982

Type:

multiple initiation site

Name:

ADIPOQ_1

Description:

adiponectin, C1Q and collagen domain containing

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	34	19,398,368 - 19,398,428	EPDNEW

Damaging Variants

Assembly: CanFam3.1

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
34	19408119	19408120	C	T	snv	Australian Cattle dog (AC023), Australian Cattle dog (AC108), Border Collie (BC0480), Shetland Sheepdog (SRS932138), Pembroke Welsh Corgi (SRS732551), Border Collie (BC518), Border Collie (BC555), Border Collie (BC597), Border Collie (LN47), Border Collie (BC485)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000013659	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030019915	UniProtKB/TrEMBL
	ENSCAFG00030019986	UniProtKB/TrEMBL
	ENSCAFG00040017203	UniProtKB/TrEMBL
	ENSCAFG00845021949	Ensembl, ENTREZGENE
Ensembl Protein	ENSCAFP00000020166	UniProtKB/TrEMBL
	ENSCAFP00000048367	UniProtKB/TrEMBL
	ENSCAFP00000050245	UniProtKB/TrEMBL
	ENSCAFP00000066158	UniProtKB/TrEMBL
	ENSCAFP00030031914	UniProtKB/TrEMBL
	ENSCAFP00030032284	UniProtKB/TrEMBL
	ENSCAFP00040027898	UniProtKB/TrEMBL
	ENSCAFP00040028062	UniProtKB/TrEMBL
	ENSCAFP00040028151	UniProtKB/TrEMBL
	ENSCAFP00040028324	UniProtKB/TrEMBL
	ENSCAFP00845030338	ENTREZGENE
	ENSCAFP00845030363	ENTREZGENE
Ensembl Transcript	ENSCAFT00000021712	UniProtKB/TrEMBL
	ENSCAFT00000066880	UniProtKB/TrEMBL
	ENSCAFT00000077761	UniProtKB/TrEMBL
	ENSCAFT00000086993	UniProtKB/TrEMBL
	ENSCAFT00030036582	UniProtKB/TrEMBL
	ENSCAFT00030037009	UniProtKB/TrEMBL
	ENSCAFT00040032092	UniProtKB/TrEMBL
	ENSCAFT00040032266	UniProtKB/TrEMBL
	ENSCAFT00040032363	UniProtKB/TrEMBL
	ENSCAFT00040032552	UniProtKB/TrEMBL
	ENSCAFT00845038743	ENTREZGENE
	ENSCAFT00845038776	ENTREZGENE
Gene3D-CATH	2.60.120.40	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	Adiponectin	UniProtKB/TrEMBL
	C1q_dom	UniProtKB/TrEMBL
	Collagen	UniProtKB/TrEMBL
	DEAD/DEAH_box_helicase_dom	UniProtKB/TrEMBL
	EIF4A_DEADc	UniProtKB/TrEMBL
	Helicase_ATP-bd	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	RNA-helicase_DEAD-box_CS	UniProtKB/TrEMBL
	RNA_helicase_DEAD_Q_motif	UniProtKB/TrEMBL
	Tumour_necrosis_fac-like_dom	UniProtKB/TrEMBL
KEGG Report	cfa:403625	UniProtKB/TrEMBL
NCBI Gene	ADIPOQ	ENTREZGENE
PANTHER	PTHR15427:SF20	UniProtKB/TrEMBL
Pfam	C1q	UniProtKB/TrEMBL
	Collagen	UniProtKB/TrEMBL
	DEAD	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
PRINTS	COMPLEMNTC1Q	UniProtKB/TrEMBL
PROSITE	C1Q	UniProtKB/TrEMBL
	DEAD_ATP_HELICASE	UniProtKB/TrEMBL
	HELICASE_ATP_BIND_1	UniProtKB/TrEMBL
	HELICASE_CTER	UniProtKB/TrEMBL
	Q_MOTIF	UniProtKB/TrEMBL
SMART	C1Q	UniProtKB/TrEMBL
	DEXDc	UniProtKB/TrEMBL
	HELICc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49842	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	A0A0B4J198_CANLF	UniProtKB/TrEMBL
	A0A5F4C5W8_CANLF	UniProtKB/TrEMBL
	A0A5F4C9W2_CANLF	UniProtKB/TrEMBL
	A0A5F4DM93_CANLF	UniProtKB/TrEMBL
	A0A8C0SW73_CANLF	UniProtKB/TrEMBL
	A0A8C0SXA1_CANLF	UniProtKB/TrEMBL
	A0A8C0SXQ2_CANLF	UniProtKB/TrEMBL
	A0A8C0T0Y5_CANLF	UniProtKB/TrEMBL
	Q76C76	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A3B0IPB0	UniProtKB/TrEMBL
VGNC ID	VGNC:37656	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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