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Gene: ABCB1 (ATP binding cassette subfamily B member 1) Canis lupus familiaris
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Symbol: ABCB1
Name: ATP binding cassette subfamily B member 1
Description: ENCODES a protein that exhibits ATP binding (inferred); ATPase activity (inferred); efflux transmembrane transporter activity (inferred); INVOLVED IN export across plasma membrane (inferred); G2/M transition of mitotic cell cycle (inferred); positive regulation of anion channel activity (inferred); PARTICIPATES IN axitinib pharmacokinetics pathway; bile acid transport pathway; clopidogrel pharmacodynamics pathway; ASSOCIATED WITH adrenocortical carcinoma (ortholog); allergic rhinitis (ortholog); Alzheimer's disease (ortholog); FOUND IN apical plasma membrane (inferred); cell surface (inferred); integral component of membrane (inferred); INTERACTS WITH 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile; allicin; digoxin
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MDR1; multidrug resistance p-glycoprotein; multidrug resistance protein 1; p-gp
Orthologs:
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11413,644,891 - 13,852,829 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog Cytomap14 NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on ABCB1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12063362
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.