GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ABCB1 | increases response to substance | EXP | | 6480464 | CTD | ABCB1 gene mutant form results in increased susceptibility to moxidectin; ABCB1 mutant form results in increased susceptibility to moxidectin | PMID:23186803 PMID:25419811 | ABCB1 | multiple interactions | EXP | | 6480464 | CTD | ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of ALB mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of DAO mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of EBF3 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of GABRQ mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of GLRA1 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of KLK6 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of MAB21L2 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of SLC10A4 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of SLC18A2 mRNA]; ABCB1 gene mutant form affects the reaction [moxidectin affects the expression of TTR mRNA] | PMID:25419811 | |
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