LOC100855552 (creatine kinase B-type) - Rat Genome Database

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Gene: LOC100855552 (creatine kinase B-type) Canis lupus familiaris
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Symbol: LOC100855552 (Ensembl: CKB)
Name: creatine kinase B-type
RGD ID: 12156223
Description: ENCODES a protein that exhibits creatine kinase activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN brain development (ortholog); cellular response to estrogen stimulus (ortholog); cellular response to wortmannin (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); adenocarcinoma (ortholog); Charcot-Marie-Tooth disease axonal type 2O (ortholog); FOUND IN dendrite (ortholog); extracellular space (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: B-CK; CKB; creatine kinase B; Creatine kinase B chain; creatine kinase, brain
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC476334  
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1871,284,104 - 71,287,379 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha870,795,385 - 70,798,712 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0871,559,900 - 71,563,227 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl871,559,903 - 71,563,745 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1871,249,019 - 71,252,346 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0871,288,738 - 71,292,065 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0871,687,984 - 71,691,311 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:3755597   PMID:3866230   PMID:30032202  


Genomics

Comparative Map Data
LOC100855552
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1871,284,104 - 71,287,379 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha870,795,385 - 70,798,712 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0871,559,900 - 71,563,227 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl871,559,903 - 71,563,745 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1871,249,019 - 71,252,346 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0871,288,738 - 71,292,065 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0871,687,984 - 71,691,311 (-)NCBIUU_Cfam_GSD_1.0
CKB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814103,519,667 - 103,522,830 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14103,519,667 - 103,522,833 (-)EnsemblGRCh38hg38GRCh38
GRCh3714103,986,004 - 103,989,167 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614103,055,749 - 103,058,923 (-)NCBINCBI36Build 36hg18NCBI36
Build 3414103,055,748 - 103,058,923NCBI
Celera1484,040,224 - 84,043,398 (-)NCBICelera
Cytogenetic Map14q32.33NCBI
HuRef1484,164,414 - 84,167,557 (-)NCBIHuRef
CHM1_114103,924,170 - 103,927,371 (-)NCBICHM1_1
T2T-CHM13v2.01497,755,711 - 97,758,874 (-)NCBIT2T-CHM13v2.0
Ckb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912111,635,789 - 111,638,772 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12111,635,795 - 111,638,772 (-)EnsemblGRCm39 Ensembl
GRCm3812111,669,355 - 111,672,338 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12111,669,361 - 111,672,338 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712112,907,566 - 112,910,549 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612112,117,169 - 112,120,076 (-)NCBIMGSCv36mm8
Celera12112,866,533 - 112,869,516 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.09NCBI
Ckb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86136,550,583 - 136,553,464 (-)NCBIGRCr8
mRatBN7.26130,729,420 - 130,732,301 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6130,729,423 - 130,732,315 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6130,896,519 - 130,899,400 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06131,192,501 - 131,195,382 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06130,559,479 - 130,562,360 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06136,142,956 - 136,145,838 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,142,956 - 136,145,837 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,270,901 - 144,273,776 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,452,215 - 136,455,122 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16136,458,401 - 136,461,309 (-)NCBI
Celera6128,284,759 - 128,287,594 (-)NCBICelera
Cytogenetic Map6q32NCBI
Ckb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555382,379,868 - 2,380,771 (-)NCBIChiLan1.0ChiLan1.0
CKB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215104,678,952 - 104,682,157 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114103,895,452 - 103,898,675 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01484,145,931 - 84,149,093 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114103,957,347 - 103,960,736 (-)NCBIpanpan1.1PanPan1.1panPan2
Ckb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086402,783,394 - 2,786,864 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366211,612,393 - 1,615,822 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366211,612,398 - 1,615,821 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CKB
(Sus scrofa - pig)
No map positions available.
CKB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12481,462,164 - 81,463,873 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605368,763,838 - 68,767,259 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ckb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247341,346,510 - 1,349,383 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247341,346,056 - 1,349,383 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LOC100855552
35 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00845033496   ⟹   ENSCAFP00845026222
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl871,559,903 - 71,563,745 (-)Ensembl
RefSeq Acc Id: XM_003639211   ⟹   XP_003639259
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1871,284,104 - 71,287,379 (-)NCBI
Dog10K_Boxer_Tasha870,795,385 - 70,798,712 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038484300   ⟹   XP_038340228
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1871,249,019 - 71,252,346 (-)NCBI
RefSeq Acc Id: XM_038545830   ⟹   XP_038401758
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0871,687,984 - 71,691,311 (-)NCBI
RefSeq Acc Id: XM_038609899   ⟹   XP_038465827
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0871,288,738 - 71,292,065 (-)NCBI
RefSeq Acc Id: XM_038674741   ⟹   XP_038530669
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0871,559,900 - 71,563,227 (-)NCBI
RefSeq Acc Id: XP_003639259   ⟸   XM_003639211
- UniProtKB: P05124 (UniProtKB/Swiss-Prot),   A0A8C0K6K2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038340228   ⟸   XM_038484300
RefSeq Acc Id: XP_038465827   ⟸   XM_038609899
RefSeq Acc Id: XP_038530669   ⟸   XM_038674741
- UniProtKB: P05124 (UniProtKB/Swiss-Prot),   A0A8C0K6K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038401758   ⟸   XM_038545830
- UniProtKB: P05124 (UniProtKB/Swiss-Prot),   A0A8C0K6K2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845026222   ⟸   ENSCAFT00845033496

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018277 UniProtKB/Swiss-Prot
  ENSCAFG00030001161 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00805013042 UniProtKB/Swiss-Prot
  ENSCAFG00845018958 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00000029035.5 UniProtKB/Swiss-Prot
  ENSCAFT00030002013.1 UniProtKB/TrEMBL
  ENSCAFT00030002044.1 UniProtKB/TrEMBL
  ENSCAFT00030002059.1 UniProtKB/Swiss-Prot
  ENSCAFT00805023772 UniProtKB/Swiss-Prot
  ENSCAFT00845033496 ENTREZGENE
  ENSCAFT00845033496.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.135.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutamine synthetase/guanido kinase, catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ATP-guanido_PTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_AS UniProtKB/Swiss-Prot
  ATP-guanido_PTrfase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gln_synth/guanido_kin_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:100855552 UniProtKB/Swiss-Prot
NCBI Gene CKB ENTREZGENE
PANTHER ARGININE OR CREATINE KINASE UniProtKB/TrEMBL
  CREATINE KINASE B-TYPE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11547 UniProtKB/Swiss-Prot
Pfam ATP-gua_Ptrans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-gua_PtransN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PHOSPHAGEN_KINASE UniProtKB/Swiss-Prot
  PHOSPHAGEN_KINASE_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHAGEN_KINASE_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glutamine synthetase/guanido kinase UniProtKB/TrEMBL
  Guanido kinase N-terminal domain UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  SSF55931 UniProtKB/Swiss-Prot
UniProt A0A8C0K6K2 ENTREZGENE
  A0A8C0M449_CANLF UniProtKB/TrEMBL
  A0A8C0RA09_CANLF UniProtKB/TrEMBL
  KCRB_CANLF UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 LOC100855552  creatine kinase B-type  CKB  creatine kinase B  Symbol and/or name change 5135510 APPROVED