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Gene: DDB1 (damage specific DNA binding protein 1) Canis lupus familiaris

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Symbol:

DDB1

Name:

damage specific DNA binding protein 1

RGD ID:

12356946

Description:

ENCODES a protein that exhibits damaged DNA binding (ortholog); INVOLVED IN cellular response to UV (ortholog); PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repair pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); communication disorder (ortholog); congenital heart disease (ortholog); FOUND IN Cul4-RING E3 ubiquitin ligase complex (inferred); Cul4A-RING E3 ubiquitin ligase complex (inferred); Cul4B-RING E3 ubiquitin ligase complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DNA damage-binding protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	55,064,720 - 55,097,623 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	55,064,729 - 55,097,627 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	53,637,465 - 53,670,146 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	56,112,716 - 56,145,419 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	56,112,714 - 56,167,311 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	55,170,743 - 55,203,394 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	54,792,588 - 54,825,289 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	55,673,233 - 55,706,147 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

communication disorder (ISO)

congenital heart disease (ISO)

Disease Progression (ISO)

intellectual disability (ISO)

leukocyte adhesion deficiency 3 (ISO)

Stomach Neoplasms (ISO)

syndromic intellectual disability (ISO)

WHITE-KERNOHAN SYNDROME (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA)

biological process involved in interaction with symbiont (IEA)

cellular response to UV (ISO)

DNA damage response (IEA)

DNA repair (IBA)

ectopic germ cell programmed cell death (IEA)

epigenetic programming in the zygotic pronuclei (IEA)

negative regulation of apoptotic process (IEA)

negative regulation of developmental process (IEA)

negative regulation of reproductive process (IEA)

positive regulation by virus of viral protein levels in host cell (IEA)

positive regulation of gluconeogenesis (IEA)

positive regulation of protein catabolic process (IEA)

positive regulation of viral genome replication (IEA)

proteasomal protein catabolic process (IEA)

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA,IEA)

protein ubiquitination (IEA)

regulation of circadian rhythm (IEA)

regulation of mitotic cell cycle phase transition (IEA)

spindle assembly involved in female meiosis (IEA)

ubiquitin-dependent protein catabolic process (IEA)

UV-damage excision repair (IEA)

viral release from host cell (IEA)

Wnt signaling pathway (IEA)

Cellular Component

Cul4-RING E3 ubiquitin ligase complex (IEA)

Cul4A-RING E3 ubiquitin ligase complex (IEA)

Cul4B-RING E3 ubiquitin ligase complex (IEA)

cytoplasm (IEA)

nucleolus (IEA)

nucleoplasm (IEA)

nucleus (IBA,IEA)

protein-containing complex (IEA)

site of double-strand break (IBA)

Molecular Function

cullin family protein binding (IEA)

damaged DNA binding (IEA,ISO)

nucleic acid binding (IEA)

protein binding (ISO)

protein-containing complex binding (IEA)

protein-macromolecule adaptor activity (IEA)

ubiquitin ligase complex scaffold activity (IEA)

WD40-repeat domain binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

altered nucleotide excision repair pathway (ISO)

nucleotide excision repair pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

DDB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	55,064,720 - 55,097,623 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	55,064,729 - 55,097,627 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	53,637,465 - 53,670,146 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	56,112,716 - 56,145,419 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	56,112,714 - 56,167,311 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	55,170,743 - 55,203,394 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	54,792,588 - 54,825,289 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	55,673,233 - 55,706,147 (+)	NCBI		UU_Cfam_GSD_1.0

DDB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	61,299,451 - 61,333,105 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	61,299,451 - 61,342,596 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	61,066,923 - 61,100,577 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	60,823,495 - 60,857,242 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	60,823,499 - 60,857,125	NCBI
Cytogenetic Map	11	q12.2	NCBI
HuRef	11	57,394,763 - 57,428,510 (-)	NCBI		HuRef
CHM1_1	11	60,949,958 - 60,983,704 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	61,288,439 - 61,322,058 (-)	NCBI		T2T-CHM13v2.0

Ddb1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	10,582,961 - 10,607,186 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	10,582,691 - 10,607,183 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	10,605,568 - 10,629,828 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	10,605,327 - 10,629,819 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	10,680,115 - 10,704,312 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	10,672,670 - 10,696,867 (+)	NCBI		MGSCv36	mm8
Celera	19	11,301,601 - 11,325,808 (+)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	6.66	NCBI

Ddb1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	216,677,810 - 216,703,605 (+)	NCBI		GRCr8
mRatBN7.2	1	207,252,890 - 207,278,685 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	207,252,890 - 207,278,676 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	215,631,459 - 215,657,329 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	222,687,016 - 222,712,802 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	215,382,012 - 215,407,798 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	226,657,561 - 226,683,356 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	226,657,561 - 226,683,347 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	233,603,490 - 233,629,285 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	213,095,187 - 213,120,986 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	204,746,264 - 204,772,059 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

Ddb1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955511	6,209,777 - 6,233,594 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955511	6,209,777 - 6,233,594 (+)	NCBI	ChiLan1.0	ChiLan1.0

DDB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	62,467,451 - 62,501,152 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	63,511,126 - 63,544,583 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	56,599,422 - 56,633,140 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	59,964,235 - 59,997,805 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	59,964,235 - 59,997,805 (-)	Ensembl	panpan1.1		panPan2

Ddb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	11,596,653 - 11,628,774 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	1,710,382 - 1,742,598 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936581	1,710,382 - 1,742,598 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DDB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	10,171,502 - 10,201,598 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	10,171,554 - 10,201,602 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	9,718,733 - 9,748,620 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DDB1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	12,508,712 - 12,543,127 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	12,508,443 - 12,544,913 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	109,887,958 - 109,922,218 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ddb1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624926	871,000 - 897,777 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624926	871,003 - 893,902 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in DDB1
328 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038425447	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038501684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038564409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038628532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_533275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000025824 ⟹ ENSCAFP00000023980

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	55,064,729 - 55,097,125 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000049486 ⟹ ENSCAFP00000037259

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	55,064,729 - 55,097,627 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000065271 ⟹ ENSCAFP00000052362

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	55,064,729 - 55,097,627 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000076041 ⟹ ENSCAFP00000063583

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	55,064,729 - 55,097,627 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845023110 ⟹ ENSCAFP00845018116

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	18	56,112,714 - 56,142,749 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845023200 ⟹ ENSCAFP00845018193

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	18	56,112,726 - 56,167,311 (+)	Ensembl

RefSeq Acc Id:

XM_038425447 ⟹ XP_038281375

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	18	56,112,716 - 56,145,419 (+)	NCBI

RefSeq Acc Id:

XM_038501684 ⟹ XP_038357612

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	18	55,170,743 - 55,203,394 (+)	NCBI

RefSeq Acc Id:

XM_038564409 ⟹ XP_038420337

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	18	55,673,233 - 55,706,147 (+)	NCBI

RefSeq Acc Id:

XM_038628532 ⟹ XP_038484460

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	18	54,792,588 - 54,825,289 (+)	NCBI

RefSeq Acc Id:

XM_533275 ⟹ XP_533275

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	18	55,064,720 - 55,097,623 (+)	NCBI
Dog10K_Boxer_Tasha	18	53,637,465 - 53,670,146 (+)	NCBI

Sequence:

show sequence

GGGCGGAGGCGGAGGCGGAGGCGGAGGCGGAGGCAGTGGAGTAGGCCGCGCGCGGGTGGGGGCC
GCCGTCTCTTCGCCGGTGTCCATTTCTCCGTCGCTGCGCTCGACCGCCGCCCCAGACCTCGACA
TGTCGTACAACTACGTGGTGACGGCCCAGAAGCCCACCGCCGTGAACGGCTGCGTGACCGGACA
CTTTACTTCAGCCGAGGACTTGAACCTGTTGATCGCCAAAAACACGAGGTTGGAGATCTATGTG
GTCACTGCTGAGGGGCTTCGGCCCGTCAAGGAGGTGGGCATGTATGGGAAGATTGCAGTCATGG
AGCTCTTCAGGCCCAAGGGGGAGAGCAAGGACCTACTCTTTATCCTGACAGCTAAATACAATGC
CTGCATCCTGGAATATAAGCAGAGTGGCGAGAGCATTGATATCATAACGCGAGCCCATGGCAAT
GTCCAGGACCGTATTGGCCGCCCCTCAGAGACTGGCATTATTGGCATCATTGACCCTGAGTGCC
GGATGATTGGCCTGCGACTCTATGATGGCCTTTTCAAGGTTATTCCGCTAGACCGGGACAATAA
AGAGCTCAAGGCCTTTAACATCCGCCTCGAGGAGCTGCATGTCATCGATGTCAAGTTCCTATAT
GGTTGCCAAGCACCTACCATCTGCTTTGTCTACCAGGACCCTCAGGGGCGGCATGTGAAAACTT
ACGAGGTGTCTCTCCGAGAGAAGGAGTTCAATAAGGGCCCTTGGAAACAGGAAAATGTAGAAGC
TGAAGCTTCCATGGTGATTGCAGTCCCAGAGCCCTTCGGAGGGGCCATCATCATTGGACAGGAA
TCAATCACCTATCACAATGGTGACAAATACCTGGCAATTGCTCCTCCTATCATCAAGCAAAGCA
CAATTGTGTGTCACAATCGTGTGGACCCCAATGGTTCCCGCTATCTGCTGGGAGACATGGAGGG
AAGGCTCTTCATGCTGCTTTTGGAGAAGGAGGAACAGATGGATGGCACTGTCACCCTCAAAGAT
CTCCGTGTGGAGCTCCTCGGAGAGACTTCTATTGCTGAATGCTTGACATACCTCGATAATGGTG
TTGTGTTTGTTGGGTCTCGCCTTGGGGACTCCCAGCTTGTGAAGCTCAATGTTGACAGCAATGA
ACAAGGCTCCTATGTAGTGGCCATGGAAACCTTTACCAATTTAGGACCCATTGTGGATATGTGT
GTGGTGGACCTGGAGAGGCAGGGACAGGGACAGCTGGTTACTTGCTCTGGGGCTTTCAAGGAAG
GTTCCTTGCGGATCATCCGGAATGGAATCGGAATCCATGAGCATGCCAGCATTGACTTACCAGG
CATCAAAGGTCTGTGGCCACTGCGGTCTGACCCAAACCGGGAGACTGATGACACTTTGGTGCTC
TCTTTTGTGGGCCAGACAAGAGTCCTCATGTTAAACGGAGAGGAAGTGGAAGAAACCGAACTGA
TGGGTTTTGTGGATGATCAGCAGACTTTCTTCTGTGGCAACGTGGCTCATCAACAACTCATCCA
GATCACTTCAGCATCTGTGAGATTGGTCTCTCAGGAACCCAAAGCTCTGGTCAGTGAGTGGAAG
GAGCCTCAGGGCAAGAACATCAGTGTGGCCTCCTGCAACAGCAGCCAGGTGGTAGTAGCTGTGG
GAAGGGCCCTCTACTACTTGCAGATCCATCCTCAGGAGCTCCGACAGATCAGCCACACAGAGAT
GGAACATGAAGTGGCCTGCTTGGACATCACGCCGCTGGGAGACAGCAATGGGCTGTCCCCTCTT
TGTGCCATTGGCCTGTGGACTGACATCTCTGCACGTATCTTGAAGCTGCCGTCTTTTGAGCTGC
TGCACAAAGAGATGCTGGGTGGAGAGATCATTCCTCGCTCCATCCTGATGACCACTTTTGAGAG
TAGCCACTATCTCCTTTGTGCCTTGGGAGATGGGGCACTTTTCTACTTCGGGCTCAACATTGAG
ACAGGCCTGTTGAGCGACCGTAAGAAGGTGACTCTGGGCACACAGCCCACGGTATTGAGGACTT
TCCGTTCTCTTTCTACCACCAACGTCTTTGCTTGCTCTGACCGCCCCACTGTCATCTACAGCAG
CAACCACAAGTTGGTCTTTTCCAATGTCAACCTCAAGGAGGTCAACTACATGTGTCCCCTCAAC
TCTGATGGGTATCCTGACAGCCTGGCACTGGCCAACAACAGCACTCTCACCATTGGCACCATCG
ACGAGATCCAGAAACTGCACATCCGCACCGTTCCCCTCTATGAGTCTCCAAGGAAGATCTGCTA
TCAGGAAGTGTCCCAGTGCTTTGGGGTCCTCTCCAGCCGGATCGAAGTCCAAGACACAAGTGGC
GGCACAACGGCCCTGAGGCCCAGTGCTAGCACCCAGGCCCTGTCCAGCAGCGTTAGCTCCAGCA
AGCTATTCTCCAGCAGCACAGCACCGCATGAGACCTCCTTTGGAGAAGAGGTGGAAGTGCACAA
TCTCCTCATCATTGACCAGCATACCTTTGAAGTGCTTCATGCCCACCAGTTTCTGCAGAATGAG
TATGCTCTAAGCCTGGTCTCCTGCAAGCTGGGCAAAGACCCCAACACGTACTTCATTGTGGGCA
CAGCCATGGTGTATCCCGAAGAGGCAGAGCCCAAGCAAGGTCGAATTGTGGTCTTTCAGTATTC
TGACGGAAAGCTACAGACTGTGGCCGAGAAGGAAGTGAAAGGAGCTGTGTACTCTATGGTGGAA
TTTAATGGGAAGCTGTTAGCCAGCATCAACAGCACGGTTCGGCTTTATGAGTGGACAACAGAAA
AGGAGCTTCGCACTGAGTGCAATCATTACAACAATATCATGGCCCTCTACCTGAAGACCAAGGG
CGACTTCATCCTGGTGGGTGACCTGATGCGATCGGTGCTGCTGCTTGCCTACAAGCCCATGGAG
GGGAACTTTGAAGAGATTGCTCGAGACTTCAATCCCAACTGGATGAGTGCTGTTGAAATCTTGG
ATGATGACAATTTCCTGGGGGCTGAAAATGCCTTTAACTTGTTTGTGTGTCAGAAGGATAGTGC
TGCCACCACTGATGAGGAGCGGCAACACCTCCAGGAGGTCGGTCTCTTCCATCTGGGTGAATTT
GTCAACGTCTTTTGCCATGGCTCTCTGGTCATGCAGAATCTGGGCGAGACTTCCACTCCTACAC
AGGGCTCGGTGCTCTTTGGCACAGTCAATGGCATGATTGGGCTGGTGACCTCGCTGTCAGAGAG
CTGGTACAACCTCCTGTTGGATATGCAGAATCGACTCAATAAAGTCATCAAGAGTGTGGGCAAG
ATTGAGCACTCTTTCTGGAGATCCTTTCATACTGAGCGAAAAACAGAACCAGCCACGGGCTTCA
TTGATGGAGACTTGATTGAGAGTTTCCTGGACATCAGCCGGCCCAAGATGCAGGAGGTTGTGGC
AAACCTTCAGTATGATGATGGCAGCGGGATGAAGCGAGAGGCCACTGCGGACGACCTGATCAAA
GTTGTGGAGGAGCTGACACGGATCCATTAGCCCAGGGCTGGGATCCCCTTTCCAGGCCCTTCCC
GAAGGCTTTGCTCTCTGCCCTGCTCCCCTCCCCCACCATTGTCTTCTTGGCCATGGGAAACCTT
TCCCTGAGCCAGCTGTCCCAGAAGCCACAGTACCTGTGTGGAAATGGGGATTTCTTTGAACTAA
AACCAGTTCACTGGAGACCTGGGAATGGGGTGAAGGTGGAATATTTTCTCCCTGGATTTTTACC
AGTCTCAGAGGATTCCAACCATCACTTTGGACCACCAAGTCTTGATTGGTGTTGCCAGTTGTCC
TCCTTCCAGGGAGGGATTTTGCAGCTCTTGGGCTGAAAGGAAGCTGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGGTGTGTGTATCACACTCATATGTTGTCCTCTGCTATCTTT
TTATTTAGATTGGGGGTGCAGGGAGGCTGTGGGTAAGGGGGAAGAGGGGGCGGGACGGGTTCAT
TGTCTCTGAAGTGAGAGCTTCCTTTTGCTTTCTGTCTTGCCTGAGAGCTTTGGGTCTGGAGGCC
TGACCACCAGGCCATGAGCTGCCCGAGTCTGAAACCTGAAGATGGTGGGTGATACCCAAGCCGC
CACAGCCTTTTTGTCTCTGGGGAACTGCCTTCTTCAGGGAGAAGGAGGTGGGGACGGTGAATTG
GTTGTTAGTTTCTGAGTTTTACCAAATAAAGTAGAATCTAAGAAGAAAGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038281375	(Get FASTA)	NCBI Sequence Viewer
	XP_038357612	(Get FASTA)	NCBI Sequence Viewer
	XP_038420337	(Get FASTA)	NCBI Sequence Viewer
	XP_038484460	(Get FASTA)	NCBI Sequence Viewer
	XP_533275	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000023980.3
	ENSCAFP00030035665.1
	ENSCAFP00040010108.1
	ENSCAFP00845018116.1
	ENSCAFP00845018193
	ENSCAFP00845018193.1

RefSeq Acc Id:

XP_533275 ⟸ XM_533275

- UniProtKB:

A0A8C0QFD6 (UniProtKB/TrEMBL), A0A8I3NKI4 (UniProtKB/TrEMBL), A0A8C0KI40 (UniProtKB/TrEMBL), A0A8I3RZS2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVM
ELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPEC
RMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKT
YEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQS
TIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNG
VVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKE
GSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETEL
MGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQGKNISVASCNSSQVVVAV
GRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFEL
LHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRT
FRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTI
DEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSS
KLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVG
TAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTE
KELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEIL
DDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPT
QGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGF
IDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH

hide sequence

Ensembl Acc Id:

ENSCAFP00000037259 ⟸ ENSCAFT00000049486

Ensembl Acc Id:

ENSCAFP00000023980 ⟸ ENSCAFT00000025824

Ensembl Acc Id:

ENSCAFP00000063583 ⟸ ENSCAFT00000076041

Ensembl Acc Id:

ENSCAFP00000052362 ⟸ ENSCAFT00000065271

RefSeq Acc Id:

XP_038357612 ⟸ XM_038501684

RefSeq Acc Id:

XP_038484460 ⟸ XM_038628532

RefSeq Acc Id:	XP_038281375 ⟸ XM_038425447
- UniProtKB:	A0A8C0QFD6 (UniProtKB/TrEMBL), A0A8I3NKI4 (UniProtKB/TrEMBL), A0A8C0KI40 (UniProtKB/TrEMBL), A0A8I3RZS2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038420337 ⟸ XM_038564409
- UniProtKB:	A0A8C0KI40 (UniProtKB/TrEMBL), A0A8C0QFD6 (UniProtKB/TrEMBL), A0A8I3NKI4 (UniProtKB/TrEMBL), A0A8I3RZS2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845018193 ⟸ ENSCAFT00845023200

Ensembl Acc Id:

ENSCAFP00845018116 ⟸ ENSCAFT00845023110

Protein Domains

Cleavage/polyadenylation specificity factor A

Promoters

RGD ID:

13686668

Promoter ID:

EPDNEW_C4737

Type:

initiation region

Name:

DDB1_1

Description:

damage specific DNA binding protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	18	55,064,787 - 55,064,847	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000016264	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030022246	UniProtKB/TrEMBL
	ENSCAFG00040006257	UniProtKB/TrEMBL
	ENSCAFG00845012984	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000025824.5	UniProtKB/TrEMBL
	ENSCAFT00030040869.1	UniProtKB/TrEMBL
	ENSCAFT00040011655.1	UniProtKB/TrEMBL
	ENSCAFT00845023110.1	UniProtKB/TrEMBL
	ENSCAFT00845023200	ENTREZGENE
	ENSCAFT00845023200.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.150.910	UniProtKB/TrEMBL
	2.130.10.10	UniProtKB/TrEMBL
InterPro	Cleavage/polyA-sp_fac_asu_C	UniProtKB/TrEMBL
	Cleavage/polyA-sp_fac_asu_N	UniProtKB/TrEMBL
	RSE1/DDB1/CFT1/CPSF1	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
KEGG Report	cfa:476067	UniProtKB/TrEMBL
NCBI Gene	DDB1	ENTREZGENE
PANTHER	DNA REPAIR/RNA PROCESSING CPSF FAMILY	UniProtKB/TrEMBL
Pfam	CPSF_A	UniProtKB/TrEMBL
	MMS1_N	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/TrEMBL
UniProt	A0A8C0KI40	ENTREZGENE
	A0A8C0QFD6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NKI4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3RZS2	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:39829	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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