PRKDC (protein kinase, DNA-activated, catalytic subunit) - Rat Genome Database

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Gene: PRKDC (protein kinase, DNA-activated, catalytic subunit) Canis lupus familiaris
Analyze
Symbol: PRKDC
Name: protein kinase, DNA-activated, catalytic subunit
RGD ID: 12330988
Description: ENCODES a protein that exhibits enzyme binding (ortholog); histone H2AXS139 kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN B cell lineage commitment (ortholog); brain development (ortholog); DNA damage response (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH severe combined immunodeficiency; adenoid cystic carcinoma (ortholog); Brain Hypoxia-Ischemia (ortholog); FOUND IN chromatin (ortholog); DNA-dependent protein kinase-DNA ligase 4 complex (ortholog); nonhomologous end joining complex (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA-dependent protein kinase catalytic subunit; DNA-PK catalytic subunit; DNA-PKcs
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12924,904 - 243,926 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2935,007 - 243,895 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha29449,958 - 669,362 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02920,665 - 241,975 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2922,025 - 241,944 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12920,944 - 240,298 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.029218,160 - 435,150 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.029285,564 - 503,393 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of innate immune response  (IEA)
B cell lineage commitment  (ISO)
brain development  (ISO)
cellular response to insulin stimulus  (IEA)
chromatin remodeling  (IEA)
DNA damage response  (IEA,ISS)
DNA recombination  (IEA)
DNA repair  (IEA)
double-strand break repair  (IBA,IEA,ISO)
double-strand break repair via nonhomologous end joining  (IEA,ISO)
ectopic germ cell programmed cell death  (ISO)
heart development  (ISO)
immature B cell differentiation  (ISO)
immunoglobulin production  (ISO)
immunoglobulin V(D)J recombination  (IBA,ISO)
innate immune response  (IEA)
intrinsic apoptotic signaling pathway in response to DNA damage  (IBA,ISO)
lymphocyte differentiation  (ISO)
maturation of 5.8S rRNA  (IEA,ISS)
mitotic G1 DNA damage checkpoint signaling  (IEA,ISS)
negative regulation of apoptotic process  (IEA)
negative regulation of cellular senescence  (ISO)
negative regulation of cGAS/STING signaling pathway  (IEA)
negative regulation of immunoglobulin production  (ISO)
negative regulation of protein phosphorylation  (ISS)
negative regulation of response to gamma radiation  (ISO)
peptidyl-serine phosphorylation  (ISO,ISS)
peptidyl-threonine phosphorylation  (ISS)
positive regulation of apoptotic process  (ISO)
positive regulation of developmental growth  (ISO)
positive regulation of double-strand break repair via nonhomologous end joining  (IEA,ISS)
positive regulation of erythrocyte differentiation  (ISS)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of immune system process  (ISO)
positive regulation of lymphocyte differentiation  (ISS)
positive regulation of platelet formation  (ISS)
positive regulation of transcription by RNA polymerase II  (IEA)
positive regulation of translation  (ISS)
pro-B cell differentiation  (ISO)
protein destabilization  (ISO)
protein phosphorylation  (ISS)
regulation of circadian rhythm  (ISS)
regulation of epithelial cell proliferation  (IEA)
regulation of hematopoietic stem cell differentiation  (ISS)
regulation of smooth muscle cell proliferation  (IEA,ISS)
response to activity  (ISO)
response to gamma radiation  (ISO)
response to ionizing radiation  (ISO)
rhythmic process  (IEA)
ribosome biogenesis  (IEA)
small-subunit processome assembly  (IEA,ISS)
somitogenesis  (ISO)
spleen development  (ISO)
T cell differentiation in thymus  (ISO)
T cell lineage commitment  (ISO)
T cell receptor V(D)J recombination  (ISO)
telomere capping  (IEA)
telomere maintenance  (IBA,ISO)
thymus development  (ISO)
V(D)J recombination  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:11867233   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PRKDC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12924,904 - 243,926 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2935,007 - 243,895 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha29449,958 - 669,362 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02920,665 - 241,975 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2922,025 - 241,944 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12920,944 - 240,298 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.029218,160 - 435,150 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.029285,564 - 503,393 (-)NCBIUU_Cfam_GSD_1.0
PRKDC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38847,773,111 - 47,960,136 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl847,773,111 - 47,960,178 (-)EnsemblGRCh38hg38GRCh38
GRCh37848,685,672 - 48,872,696 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36848,848,222 - 49,035,296 (-)NCBINCBI36Build 36hg18NCBI36
Build 34848,848,221 - 49,035,296NCBI
Celera844,671,051 - 44,858,151 (-)NCBICelera
Cytogenetic Map8q11.21NCBI
HuRef844,148,581 - 44,335,706 (-)NCBIHuRef
CHM1_1848,738,053 - 48,925,105 (-)NCBICHM1_1
T2T-CHM13v2.0848,149,356 - 48,336,384 (-)NCBIT2T-CHM13v2.0
Prkdc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391615,455,698 - 15,660,103 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1615,455,730 - 15,660,099 (+)EnsemblGRCm39 Ensembl
GRCm381615,637,444 - 15,842,239 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1615,637,866 - 15,842,235 (+)EnsemblGRCm38mm10GRCm38
MGSCv371615,637,959 - 15,842,332 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361615,551,467 - 15,755,813 (+)NCBIMGSCv36mm8
Celera1616,214,291 - 16,413,213 (+)NCBICelera
Cytogenetic Map16A2NCBI
cM Map1610.09NCBI
Prkdc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81198,544,952 - 98,762,499 (-)NCBIGRCr8
mRatBN7.21185,040,790 - 85,258,357 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1185,040,792 - 85,257,952 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1193,767,902 - 93,984,974 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01186,429,067 - 86,646,132 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01185,482,663 - 85,699,739 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,293,547 - 89,510,948 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,293,696 - 89,510,871 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01192,347,175 - 92,565,022 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,951,420 - 87,169,229 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,992,362 - 87,209,825 (-)NCBI
Celera1183,781,535 - 83,998,574 (-)NCBICelera
Cytogenetic Map11q23NCBI
Prkdc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554547,733,978 - 7,890,867 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554547,733,697 - 7,890,896 (-)NCBIChiLan1.0ChiLan1.0
PRKDC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2763,407,112 - 63,593,508 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1839,100,871 - 39,287,251 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0844,201,391 - 44,386,803 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1841,593,022 - 41,778,299 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl841,593,029 - 41,778,299 (-)Ensemblpanpan1.1panPan2
Prkdc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530379,533,069 - 79,697,823 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365904,722,873 - 4,890,156 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365904,722,914 - 4,887,615 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKDC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl479,687,375 - 79,846,656 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1479,687,375 - 79,850,146 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2487,185,946 - 87,343,690 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRKDC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1843,915,226 - 44,119,547 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl843,914,636 - 44,119,541 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603997,968,963 - 98,158,648 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prkdc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247357,534,506 - 7,700,305 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247357,534,483 - 7,702,079 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PRKDC
1754 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001006651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014109168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014109170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014109171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014109172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022412201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022412203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022412204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038441061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038441062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038441063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038441064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005304005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000010616   ⟹   ENSCAFP00000009842
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2935,007 - 243,895 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000059988   ⟹   ENSCAFP00000065390
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2935,007 - 237,877 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000060250   ⟹   ENSCAFP00000064041
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2935,007 - 241,609 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000064235   ⟹   ENSCAFP00000060718
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2935,007 - 241,609 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000068077   ⟹   ENSCAFP00000053308
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2935,007 - 241,609 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000072088   ⟹   ENSCAFP00000055719
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2935,007 - 243,895 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000072240   ⟹   ENSCAFP00000064872
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2935,007 - 237,877 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000079094   ⟹   ENSCAFP00000064095
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2935,007 - 241,609 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000081819   ⟹   ENSCAFP00000045113
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2935,007 - 237,877 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845049037   ⟹   ENSCAFP00845038476
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2922,025 - 241,944 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845049363   ⟹   ENSCAFP00845038732
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2922,025 - 241,944 (-)Ensembl
RefSeq Acc Id: NM_001006651   ⟹   NP_001006652
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12926,553 - 243,895 (-)NCBI
Dog10K_Boxer_Tasha29449,958 - 669,362 (-)NCBI
ROS_Cfam_1.02922,311 - 241,944 (-)NCBI
UMICH_Zoey_3.12920,944 - 240,298 (-)NCBI
UNSW_CanFamBas_1.029218,160 - 435,150 (-)NCBI
UU_Cfam_GSD_1.029285,564 - 503,393 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038441061   ⟹   XP_038296989
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02920,665 - 241,975 (-)NCBI
RefSeq Acc Id: XM_038441062   ⟹   XP_038296990
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02920,665 - 241,975 (-)NCBI
RefSeq Acc Id: XM_038441063   ⟹   XP_038296991
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02920,665 - 241,975 (-)NCBI
RefSeq Acc Id: XM_038441064   ⟹   XP_038296992
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02920,665 - 241,975 (-)NCBI
RefSeq Acc Id: XR_005304005
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02922,378 - 241,940 (-)NCBI
RefSeq Acc Id: NP_001006652   ⟸   NM_001006651
- UniProtKB: A0A8I3PUI7 (UniProtKB/TrEMBL),   A0A8I3SB89 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000060718   ⟸   ENSCAFT00000064235
Ensembl Acc Id: ENSCAFP00000064041   ⟸   ENSCAFT00000060250
Ensembl Acc Id: ENSCAFP00000064095   ⟸   ENSCAFT00000079094
Ensembl Acc Id: ENSCAFP00000065390   ⟸   ENSCAFT00000059988
Ensembl Acc Id: ENSCAFP00000009842   ⟸   ENSCAFT00000010616
Ensembl Acc Id: ENSCAFP00000053308   ⟸   ENSCAFT00000068077
Ensembl Acc Id: ENSCAFP00000045113   ⟸   ENSCAFT00000081819
Ensembl Acc Id: ENSCAFP00000064872   ⟸   ENSCAFT00000072240
Ensembl Acc Id: ENSCAFP00000055719   ⟸   ENSCAFT00000072088
RefSeq Acc Id: XP_038296990   ⟸   XM_038441062
- Peptide Label: isoform X2
- UniProtKB: A0A8I3SB89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038296992   ⟸   XM_038441064
- Peptide Label: isoform X4
- UniProtKB: A0A8I3SB89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038296991   ⟸   XM_038441063
- Peptide Label: isoform X3
- UniProtKB: A0A8I3SB89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038296989   ⟸   XM_038441061
- Peptide Label: isoform X1
- UniProtKB: A0A8I3SB89 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845038732   ⟸   ENSCAFT00845049363
Ensembl Acc Id: ENSCAFP00845038476   ⟸   ENSCAFT00845049037
Protein Domains
FAT   FATC   PI3K/PI4K catalytic

Promoters
RGD ID:13688388
Promoter ID:EPDNEW_C6457
Type:multiple initiation site
Name:PRKDC_1
Description:protein kinase, DNA-activated, catalytic polypeptide
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.129243,925 - 243,985EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006555 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845027748 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010616.5 UniProtKB/TrEMBL
  ENSCAFT00845049037 ENTREZGENE
  ENSCAFT00845049037.1 UniProtKB/TrEMBL
  ENSCAFT00845049363.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1070.11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DDR_Repair_Kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA-PK_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA-PKcs_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNAPKcs_CC1-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNAPKcs_CC3 UniProtKB/TrEMBL
  DNAPKcs_CC5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FATC_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUC194 UniProtKB/Swiss-Prot
  PI3/4_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_cat_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIK-rel_kinase_FAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIK_FAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene PRKDC ENTREZGENE
PANTHER ATAXIA TELANGIECTASIA MUTATED ATM -RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DNA-PKcs_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNAPKcs_CC1-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNAPKcs_CC5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FATC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUC194 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_PI4_kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FATC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_4_KINASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_4_KINASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_4_KINASE_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FATC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUC194 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3Kc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I3PUI7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3SB89 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SBY5_CANLF UniProtKB/TrEMBL
  PRKDC_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:44989 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-26 PRKDC  protein kinase, DNA-activated, catalytic subunit    protein kinase, DNA-activated, catalytic polypeptide  Symbol and/or name change 5135510 APPROVED