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Gene: NR1I2 (nuclear receptor subfamily 1 group I member 2) Canis lupus familiaris
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Symbol: NR1I2
Name: nuclear receptor subfamily 1 group I member 2
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); drug binding (inferred); nuclear receptor activity (inferred); INVOLVED IN exogenous drug catabolic process (inferred); intracellular receptor signaling pathway (inferred); steroid hormone mediated signaling pathway (inferred); ASSOCIATED WITH adenocarcinoma (ortholog); Barrett's esophagus (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN host cell nucleus (inferred); intermediate filament cytoskeleton (inferred); nuclear body (inferred); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime; clotrimazole
Type: protein-coding
RefSeq Status: MODEL
Also known as: pregnane X receptor; PXR
Orthologs:
Homo sapiens (human) : NR1I2 (nuclear receptor subfamily 1 group I member 2)  HGNC  Alliance
Mus musculus (house mouse) : Nr1i2 (nuclear receptor subfamily 1, group I, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nr1i2 (nuclear receptor subfamily 1, group I, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr1i2 (nuclear receptor subfamily 1 group I member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr1i2 (nuclear receptor subfamily 1 group I member 2)
Sus scrofa (pig) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
Chlorocebus sabaeus (African green monkey) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
Heterocephalus glaber (naked mole-rat) : Nr1i2 (nuclear receptor subfamily 1 group I member 2)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3323,432,690 - 23,455,347 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13323,444,367 - 23,456,405 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on NR1I2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12257278
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.