MAT1A (methionine adenosyltransferase 1A) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: MAT1A (methionine adenosyltransferase 1A) Canis lupus familiaris
Analyze
Symbol: MAT1A
Name: methionine adenosyltransferase 1A
RGD ID: 12107731
Description: ENCODES a protein that exhibits ADP binding (ortholog); amino acid binding (ortholog); ATP binding (ortholog); INVOLVED IN protein-containing complex assembly (ortholog); S-adenosylmethionine biosynthetic process (ortholog); PARTICIPATES IN methionine cycle/metabolic pathway; ASSOCIATED WITH amino acid metabolic disorder (ortholog); brain disease (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cytosol (ortholog); nuclear matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: S-adenosylmethionine synthase; S-adenosylmethionine synthase isoform type-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1429,450,857 - 29,467,251 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl429,452,601 - 29,466,929 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha429,575,218 - 29,592,037 (-)NCBI
ROS_Cfam_1.0429,753,050 - 29,769,565 (-)NCBI
UMICH_Zoey_3.1429,622,538 - 29,639,457 (-)NCBI
UNSW_CanFamBas_1.0429,825,220 - 29,841,704 (-)NCBI
UU_Cfam_GSD_1.0430,179,220 - 30,195,966 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,ISO)
nuclear matrix  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
MAT1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1429,450,857 - 29,467,251 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl429,452,601 - 29,466,929 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha429,575,218 - 29,592,037 (-)NCBI
ROS_Cfam_1.0429,753,050 - 29,769,565 (-)NCBI
UMICH_Zoey_3.1429,622,538 - 29,639,457 (-)NCBI
UNSW_CanFamBas_1.0429,825,220 - 29,841,704 (-)NCBI
UU_Cfam_GSD_1.0430,179,220 - 30,195,966 (-)NCBI
MAT1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1080,271,820 - 80,289,658 (-)EnsemblGRCh38hg38GRCh38
GRCh381080,271,820 - 80,289,658 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371082,031,576 - 82,049,414 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361082,021,556 - 82,039,414 (-)NCBINCBI36hg18NCBI36
Build 341082,021,556 - 82,039,230NCBI
Celera1076,021,909 - 76,039,786 (-)NCBI
Cytogenetic Map10q22.3NCBI
HuRef1075,874,785 - 75,892,650 (-)NCBIHuRef
CHM1_11082,314,612 - 82,332,492 (-)NCBICHM1_1
Mat1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391440,826,969 - 40,846,385 (+)NCBIGRCm39mm39
GRCm39 Ensembl1440,826,992 - 40,846,369 (+)Ensembl
GRCm381441,105,012 - 41,124,428 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1441,105,035 - 41,124,412 (+)EnsemblGRCm38mm10GRCm38
MGSCv371441,918,670 - 41,937,701 (+)NCBIGRCm37mm9NCBIm37
MGSCv361440,014,094 - 40,033,125 (+)NCBImm8
Celera1437,265,428 - 37,284,459 (+)NCBICelera
Cytogenetic Map14BNCBI
Mat1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21616,983,084 - 17,001,284 (+)NCBI
Rnor_6.0 Ensembl1618,690,246 - 18,709,133 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01618,690,649 - 18,709,135 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01618,560,492 - 18,578,747 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41617,548,582 - 17,563,989 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11617,548,582 - 17,562,884 (+)NCBI
Celera1617,208,280 - 17,226,582 (+)NCBICelera
Cytogenetic Map16p14NCBI
Mat1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955510281,331 - 300,985 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955510283,860 - 300,991 (-)NCBIChiLan1.0ChiLan1.0
MAT1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11080,280,063 - 80,298,302 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1080,280,063 - 80,298,291 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01076,677,815 - 76,697,512 (-)NCBIMhudiblu_PPA_v0panPan3
Mat1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721351,267,381 - 51,283,984 (+)NCBI
SpeTri2.0NW_004936716126,628 - 142,986 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAT1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1482,109,404 - 82,127,049 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11482,109,405 - 82,126,487 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21488,716,155 - 88,733,936 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAT1A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1951,540,162 - 51,558,076 (+)NCBI
ChlSab1.1 Ensembl951,540,162 - 51,558,576 (+)Ensembl
Vero_WHO_p1.0NW_02366604811,863,034 - 11,882,962 (+)NCBI
Mat1a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248416,843,725 - 6,864,700 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 6 6
Low 6 6 8 5
Below cutoff 5 5 10 6 6 4 8 5 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000025100   ⟹   ENSCAFP00000023298
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl429,452,601 - 29,466,929 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000081732   ⟹   ENSCAFP00000062817
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl429,452,601 - 29,466,929 (-)Ensembl
RefSeq Acc Id: XM_014112924   ⟹   XP_013968399
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1429,450,857 - 29,467,251 (-)NCBI
Dog10K_Boxer_Tasha429,575,218 - 29,592,037 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038473405   ⟹   XP_038329333
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1429,622,538 - 29,639,457 (-)NCBI
RefSeq Acc Id: XM_038534474   ⟹   XP_038390402
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0430,179,220 - 30,195,966 (-)NCBI
RefSeq Acc Id: XM_038598800   ⟹   XP_038454728
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0429,825,220 - 29,841,704 (-)NCBI
RefSeq Acc Id: XM_038663071   ⟹   XP_038518999
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0429,753,050 - 29,769,565 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_013968399   ⟸   XM_014112924
- UniProtKB: E2R557 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000023298   ⟸   ENSCAFT00000025100
RefSeq Acc Id: ENSCAFP00000062817   ⟸   ENSCAFT00000081732
RefSeq Acc Id: XP_038329333   ⟸   XM_038473405
RefSeq Acc Id: XP_038454728   ⟸   XM_038598800
RefSeq Acc Id: XP_038518999   ⟸   XM_038663071
RefSeq Acc Id: XP_038390402   ⟸   XM_038534474
Promoters
RGD ID:13682941
Promoter ID:EPDNEW_C1010
Type:initiation region
Name:MAT1A_1
Description:methionine adenosyltransferase 1A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1429,467,020 - 29,467,080EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015807 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000023298 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000062817 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000025100 UniProtKB/TrEMBL
  ENSCAFT00000081732 UniProtKB/TrEMBL
InterPro ADOMET_SYNTHASE_CS UniProtKB/TrEMBL
  S-AdoMet_synt_C UniProtKB/TrEMBL
  S-AdoMet_synt_central UniProtKB/TrEMBL
  S-AdoMet_synt_N UniProtKB/TrEMBL
  S-AdoMet_synthetase UniProtKB/TrEMBL
  S-AdoMet_synthetase_sfam UniProtKB/TrEMBL
KEGG Report cfa:608788 UniProtKB/TrEMBL
NCBI Gene MAT1A ENTREZGENE
PANTHER PTHR11964 UniProtKB/TrEMBL
Pfam S-AdoMet_synt_C UniProtKB/TrEMBL
  S-AdoMet_synt_M UniProtKB/TrEMBL
  S-AdoMet_synt_N UniProtKB/TrEMBL
PIRSF MAT UniProtKB/TrEMBL
PROSITE ADOMET_SYNTHASE_1 UniProtKB/TrEMBL
  ADOMET_SYNTHASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF55973 UniProtKB/TrEMBL
TIGRFAMs metK UniProtKB/TrEMBL
UniProt A0A5F4DDB2_CANLF UniProtKB/TrEMBL
  E2R557 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43037 ENTREZGENE