DLAT (dihydrolipoamide S-acetyltransferase) - Rat Genome Database

DLAT (dihydrolipoamide S-acetyltransferase) - Rat Genome Database

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Gene: DLAT (dihydrolipoamide S-acetyltransferase) Canis lupus familiaris

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Symbol:

DLAT

Name:

dihydrolipoamide S-acetyltransferase

RGD ID:

12388517

Description:

ENCODES a protein that exhibits dihydrolipoyllysine-residue acetyltransferase activity (ortholog); INVOLVED IN pyruvate decarboxylation to acetyl-CoA (ortholog); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria pathway; Leigh disease pathway; ASSOCIATED WITH ataxia telangiectasia (ortholog); BH4-deficient hyperphenylalaninemia A (ortholog); Carney-Stratakis syndrome (ortholog); FOUND IN pyruvate dehydrogenase complex (ortholog)

Type:

protein-coding

RefSeq Status:

Previously known as:

dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	21,062,833 - 21,094,235 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	21,064,026 - 21,094,153 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	20,985,229 - 21,016,566 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	21,086,208 - 21,117,183 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	21,086,325 - 21,117,555 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	21,147,724 - 21,178,540 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	21,047,717 - 21,079,036 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	21,096,415 - 21,127,748 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DLAT	Dog	Sleep Deprivation		ISO	Dlat (Rattus norvegicus)	9068941	mRNA:decreased expression:cerebral cortex	RGD	PMID:16923172 and REF_RGD_ID:2313667

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DLAT	Dog	ataxia telangiectasia		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: Ataxia-telangiectasia syndrome	ClinVar	PMID:23807571 more ...
DLAT	Dog	BH4-deficient hyperphenylalaninemia A		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: BH4-deficient hyperphenylalaninemia A	ClinVar	PMID:28492532
DLAT	Dog	Carney-Stratakis syndrome		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: Carney-Stratakis syndrome	ClinVar	PMID:15531530 more ...
DLAT	Dog	chromosome 11 partial duplication syndrome		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: Distal trisomy 11q	ClinVar	PMID:25741868
DLAT	Dog	congenital disorder of glycosylation Il		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: ALG9 congenital disorder of glycosylation	ClinVar	PMID:25966638 and PMID:28492532
DLAT	Dog	dilated cardiomyopathy 1II		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dilated cardiomyopathy 1II	ClinVar	PMID:28492532
DLAT	Dog	genetic disease		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:25741868 more ...
DLAT	Dog	intellectual disability		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: Intellectual disability	ClinVar
DLAT	Dog	prostate cancer		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: Malignant tumor of prostate	ClinVar	PMID:23265383
DLAT	Dog	Pyruvate Dehydrogenase E2 Deficiency		ISO	DLAT (Homo sapiens)	8554872	ClinVar Annotator: match by term: Pyruvate dehydrogenase E2 deficiency	ClinVar	PMID:16049940 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DLAT	Dog	Chemical and Drug Induced Liver Injury		ISO	DLAT (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25231249
DLAT	Dog	Myocardial Ischemia		ISO	DLAT (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16214533

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DLAT	Dog	Pyruvate Dehydrogenase E2 Deficiency		ISO	DLAT (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DLAT	Dog	pyruvate catabolic process	involved_in	IEA	UniProtKB:Q8BMF4 and ensembl:ENSMUSP00000034567	150520179		Ensembl	GO_REF:0000107
DLAT	Dog	pyruvate decarboxylation to acetyl-CoA		ISO	Dlat (Rattus norvegicus)	9068941		RGD	PMID:7487891 and REF_RGD_ID:1599112
DLAT	Dog	pyruvate decarboxylation to acetyl-CoA	involved_in	IBA	MGI:2385311 more ...	150520179		GO_Central	GO_REF:0000033
DLAT	Dog	pyruvate decarboxylation to acetyl-CoA	involved_in	IEA	UniProtKB:P10515 more ...	150520179		Ensembl	GO_REF:0000107
DLAT	Dog	pyruvate decarboxylation to acetyl-CoA	involved_in	IEA	InterPro:IPR045257	150520179		InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DLAT	Dog	mitochondrial matrix	located_in	IEA	UniProtKB-SubCell:SL-0170	150520179		UniProt	GO_REF:0000044
DLAT	Dog	mitochondrial matrix	is_active_in	IEA	UniProtKB:Q8BMF4 and ensembl:ENSMUSP00000034567	150520179		Ensembl	GO_REF:0000107
DLAT	Dog	mitochondrion	located_in	IEA	UniProtKB:P10515 more ...	150520179		Ensembl	GO_REF:0000107
DLAT	Dog	pyruvate dehydrogenase complex	part_of	IEA	UniRule:UR000124451	150520179		UniProt	GO_REF:0000104
DLAT	Dog	pyruvate dehydrogenase complex	part_of	IBA	PANTHER:PTN000568044 more ...	150520179		GO_Central	GO_REF:0000033
DLAT	Dog	pyruvate dehydrogenase complex	part_of	IEA	UniProtKB:P10515 and ensembl:ENSP00000280346	150520179		Ensembl	GO_REF:0000107
DLAT	Dog	pyruvate dehydrogenase complex		ISO	Dlat (Rattus norvegicus)	9068941		RGD	PMID:7487891 and REF_RGD_ID:1599112
DLAT	Dog	pyruvate dehydrogenase complex	part_of	IEA	InterPro:IPR006257 and InterPro:IPR045257	150520179		InterPro	GO_REF:0000002

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DLAT	Dog	acetyltransferase activity	enables	IEA	UniProtKB:Q8BMF4 and ensembl:ENSMUSP00000034567	150520179		Ensembl	GO_REF:0000107
DLAT	Dog	acyltransferase activity	enables	IEA	InterPro:IPR001078 more ...	150520179		InterPro	GO_REF:0000002
DLAT	Dog	acyltransferase activity	enables	IEA	UniProtKB-KW:KW-0012	150520179		UniProt	GO_REF:0000043
DLAT	Dog	dihydrolipoyllysine-residue acetyltransferase activity		ISO	Dlat (Rattus norvegicus)	9068941		RGD	PMID:7487891 and REF_RGD_ID:1599112
DLAT	Dog	dihydrolipoyllysine-residue acetyltransferase activity	enables	IBA	PANTHER:PTN002351721 more ...	150520179		GO_Central	GO_REF:0000033
DLAT	Dog	dihydrolipoyllysine-residue acetyltransferase activity	enables	IEA	UniRule:UR000124451	150520179		UniProt	GO_REF:0000104
DLAT	Dog	dihydrolipoyllysine-residue acetyltransferase activity	enables	IEA	UniProtKB:P10515 and ensembl:ENSP00000280346	150520179		Ensembl	GO_REF:0000107
DLAT	Dog	dihydrolipoyllysine-residue acetyltransferase activity	enables	IEA	InterPro:IPR006257	150520179		InterPro	GO_REF:0000002
DLAT	Dog	identical protein binding	enables	IEA	UniProtKB:P10515 and ensembl:ENSP00000280346	150520179		Ensembl	GO_REF:0000107
DLAT	Dog	protein binding	enables	ISO	UniProtKB:Q9Y6E7	9068941	PMID:25525879	IntAct	PMID:25525879
DLAT	Dog	protein binding	enables	ISO	UniProtKB:P11177	9068941	PMID:18206651	IntAct	PMID:18206651
DLAT	Dog	protein binding	enables	ISO	UniProtKB:P11177 and UniProtKB:Q15120	9068941	PMID:33961781	IntAct	PMID:33961781
DLAT	Dog	protein binding	enables	ISO	UniProtKB:Q15120	9068941	PMID:15861126 more ...	UniProt	PMID:15861126 more ...
DLAT	Dog	pyruvate dehydrogenase (NAD+) activity	contributes_to	IEA	UniProtKB:P10515 and ensembl:ENSP00000280346	150520179		Ensembl	GO_REF:0000107
DLAT	Dog	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	150520179		UniProt	GO_REF:0000043

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DLAT	Dog	pyruvate metabolic pathway		ISO	DLAT (Homo sapiens)	9068941		RGD	PMID:11795479 and REF_RGD_ID:2307427

Imported Annotations - SMPDB

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DLAT	Dog	citric acid cycle pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00057
DLAT	Dog	fumaric aciduria pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00547
DLAT	Dog	Leigh disease pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00196
DLAT	Dog	mitochondrial complex II deficiency pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00548
DLAT	Dog	primary hyperoxaluria type 2 pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00558
DLAT	Dog	pyruvate decarboxylase deficiency pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00212
DLAT	Dog	pyruvate dehydrogenase E1 deficiency pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00334
DLAT	Dog	pyruvate dehydrogenase E2 deficiency pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00551
DLAT	Dog	pyruvate dehydrogenase E3 deficiency pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00550
DLAT	Dog	pyruvate kinase deficiency of red cells pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00559
DLAT	Dog	pyruvate metabolic pathway		ISO	DLAT (Homo sapiens)	9068941		SMPDB	SMP:00060

PMID:22301074	PMID:30032202

DLAT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	21,062,833 - 21,094,235 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	21,064,026 - 21,094,153 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	20,985,229 - 21,016,566 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	21,086,208 - 21,117,183 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	21,086,325 - 21,117,555 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	21,147,724 - 21,178,540 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	21,047,717 - 21,079,036 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	21,096,415 - 21,127,748 (-)	NCBI		UU_Cfam_GSD_1.0

DLAT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	112,025,408 - 112,064,404 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	112,025,033 - 112,064,404 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	111,896,132 - 111,935,128 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	111,401,381 - 111,439,799 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	111,401,387 - 111,439,798	NCBI
Celera	11	109,048,752 - 109,088,192 (+)	NCBI		Celera
Cytogenetic Map	11	q23.1	NCBI
HuRef	11	107,819,561 - 107,858,905 (+)	NCBI		HuRef
CHM1_1	11	111,778,793 - 111,818,192 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	112,035,650 - 112,074,647 (+)	NCBI		T2T-CHM13v2.0

Dlat
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	50,545,933 - 50,571,080 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	50,545,933 - 50,571,080 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	50,634,633 - 50,659,780 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	50,634,633 - 50,659,780 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	50,442,738 - 50,467,885 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	50,386,865 - 50,412,010 (-)	NCBI		MGSCv36	mm8
Celera	9	47,920,941 - 47,946,308 (-)	NCBI		Celera
Cytogenetic Map	9	A5.3	NCBI
cM Map	9	27.75	NCBI

Dlat
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	59,875,537 - 59,900,947 (-)	NCBI		GRCr8
mRatBN7.2	8	50,979,151 - 51,004,435 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	50,978,051 - 51,004,479 (-)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	1	33,231,226 - 33,233,129 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	56,484,986 - 56,510,281 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	54,763,886 - 54,789,211 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	52,628,160 - 52,653,457 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	55,062,549 - 55,087,832 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	55,062,551 - 55,087,832 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	53,659,920 - 53,685,238 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	53,989,491 - 54,014,779 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	54,008,592 - 54,033,135 (-)	NCBI
Celera	8	50,507,581 - 50,552,393 (-)	NCBI		Celera
Cytogenetic Map	8	q23	NCBI

Dlat
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	13,718,067 - 13,744,239 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	13,718,091 - 13,746,220 (+)	NCBI	ChiLan1.0	ChiLan1.0

DLAT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	112,770,172 - 112,813,947 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	113,864,456 - 113,909,461 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	106,910,857 - 106,950,851 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	110,755,310 - 110,793,876 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	110,756,001 - 110,792,795 (+)	Ensembl	panpan1.1		panPan2

Dlat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	94,268,188 - 94,312,532 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936612	2,393,071 - 2,437,522 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936612	2,395,452 - 2,437,592 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DLAT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	39,738,564 - 39,796,806 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	39,738,639 - 39,763,813 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	44,595,812 - 44,605,405 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	9	44,530,186 - 44,541,155 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DLAT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	103,379,165 - 103,419,585 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	103,380,426 - 103,420,386 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	22,562,984 - 22,603,121 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dlat
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624784	7,181,671 - 7,214,751 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624784	7,181,550 - 7,216,779 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

.

Variants in DLAT
348 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_038475024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038536151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038600345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_546524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000022258 ⟹ ENSCAFP00000020671

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	21,064,026 - 21,094,153 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000069257 ⟹ ENSCAFP00000055186

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	21,064,026 - 21,094,153 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845003019 ⟹ ENSCAFP00845002410

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	21,086,325 - 21,117,555 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845003043 ⟹ ENSCAFP00845002429

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	21,086,325 - 21,117,555 (-)	Ensembl

RefSeq Acc Id:

XM_038475024 ⟹ XP_038330952

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	21,147,724 - 21,178,540 (-)	NCBI

RefSeq Acc Id:

XM_038536151 ⟹ XP_038392079

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	21,096,415 - 21,127,748 (-)	NCBI

RefSeq Acc Id:

XM_038600345 ⟹ XP_038456273

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	21,047,717 - 21,079,036 (-)	NCBI

RefSeq Acc Id:

XM_038664888 ⟹ XP_038520816

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	21,086,208 - 21,117,183 (-)	NCBI

RefSeq Acc Id:

XM_546524 ⟹ XP_546524

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	21,062,833 - 21,094,235 (-)	NCBI
Dog10K_Boxer_Tasha	5	20,985,229 - 21,016,566 (-)	NCBI

Sequence:

show sequence

GGCTGACGGCAGCGGCGCCCTGCTCTCGGAGAGGTCACTCCGGAGACGGCGTTGGTGTCGGGGTGTGGGGGTTGCTGGCACTATGTGGCGCGTCTGTGCTCGGCGGGCCCGGAATGCGGCCCCAAGGG
CAGGATTCGCGGTTCGGAGGGCGGCCTTGCGGGAGGAGCCGGCAGCTCCGCGCGTGACCTCGCGCGCTGGCGCGGCCCCGGCTCGTTGCAGTAGTGGGACTGCGGGGTCCGGCGGGGTCCGGGCGCTC
TGCAGCGGGAGCCTCAGCTCGTGGGCGACGCAGAGGAATCGCCTCCTGCTGCAGCTGCTGGGGTCGTCCGGCCGCCGCTGCTATAGCCTGCCCCCGCATCAGAAGGTTCCTTTGCCCTCTCTTTCCCC
CACAATGCAGGCAGGCACCATAGCCCGTTGGGAAAAAAAAGAAGGGGAAAAAATCAATGAGGGTGAACTAATTGCAGAGGTTGAAACCGATAAAGCCACTGTTGGATTTGAGAGCCTGGAGGAGTGTT
ACATGGCAAAGATACTTGTTGCTGAAGGTACCAGAGATGTTCCAGTTGGAGCCATCATCTGTATCACAGTTGAAAAGCCTGAGGATATTGAGGCCTTTAAAAATTACACATTGGATTCCTCCGCAGCA
CCTACCCCACAAGCAGCTGCAGCACCAACCCCTGTTGCCCCTACTTTGCCACCTACACCTCCCGCTCAGGCTCCTGGTAGCTCCTACCCCACTCACATGCAGGTGGTTCTTCCTGCTCTCTCTCCTAC
CATGACCATGGGCACAGTTCAGAGATGGGAAAAAAAAGTGGGTGAGAAGCTAAGTGAAGGAGATTTATTGGCAGAGATAGAGACTGACAAGGCCACTATAGGTTTTGAAGTACAGGAGGAGGGTTACC
TGGCAAAAATCTTGATCCCTGAAGGCACAAGAGATGTCCCTCTAGGAACCCCACTTTGTATCATTGTAGAAAAAGAGGAAGACATACCAGCATTTGCTGACTATAGGCCAACTGAAGTAACTGATTTA
AAACCACAGGCCCCACCATCTACCCCACCCCCGGTGGCCCCTGTTCCTCCAACTCCCCAACCTGTCACTCCTACACCTTCAGCCCCCCGCCCAGCTACTCCTGCTGGTCCCAAGGGAAGATTGTTTGC
AAGCCCACTTGCAAAGAAATTGGCAGCAGAGAAAGGTATTGACCTTACACAAGTAAAAGGGACGGGACCAGAAGGCAGAATCATCAAGAAGGATGTCGACTCTTTTGTGCCTACTAAAGCTGCTCCTG
CTCCAGCAGCTGCTGTGCCTGCTGCGGTTCCAGGAGTGGCACCCGTTCCTTCAGGGGTCTTCACGGACGTTCCAATCAGCAACATTCGTCGGGTTATTGCACAGAGATTAATGCAGTCTAAGCAAACC
ATACCTCATTATTACCTTTCCATTGATGTAAATATGGGAGAAGTTTTGTTGGTACGGAAAGAACTTAATAAGATGTTAGAAGGGAGAAGCAAAATTTCTGTCAATGACTTCATCATAAAAGCTTCAGC
TTTGGCATGTTTAAAAGTTCCTGAAGCAAATTCCTCTTGGCTGGACACAGTTATAAGACAAAACCATGTCGTGGATGTCAGTGTTGCAGTCAGCACTCCTGCAGGACTCATTACACCTATTGTATTTA
ATGCACATATTAAAGGACTGGAAGCTATTGCTAATGATGTTGTTTCTTTAGCAACCAAAGCACGAGAGGGTAAACTACAGCCTCATGAGTTCCAGGGTGGCACTTTTACAATCTCCAATTTAGGAATG
TTTGGAATTAAGAACTTCTCTGCTATTATTAACCCACCTCAAGCATGTATTTTGGCAATTGGTGCTTCAGAGGATAGATTGGTTCCAGCAGATAATGAAAAAGGATTTGATGTGGCTAGCATGATGTC
TGTTACACTCAGTTGTGATCATCGAGTTGTGGATGGAGCAGTTGGAGCCCAGTGGCTTGCTGAGTTTAGAAAGTACCTTGAAAAACCTATCACCATGTTGTTATAATTAACCCAAGAACTTCTAGACT
CTCCCAGGTCACAGTGGTTCATTCTTACCAAGATATATATATGTTACTACACAGGTGGTTCTTTTTATTTTAAAGTTTTAACCAGTTATTTTTGAGTCTGTCCAGATAAGTTATTTGTAATGGGCATT
ACTGAATTTTTTTAAATGCCAATTACACCCACATATTGTACACATTTAATGAACACCAGATTTTGAGCTGTGTATTCCTAGTCAGGGGAACATGTGGCCTGGCCCTTTGGTGATAAGTACTTCCATTG
GGAAATGTAGAGGTAGGATTGTGGTTTCCTGTTGAAACAGATACATAAAAGTAATCTGGATGAAATCTTGAGGTTTTGAAATGTAATTGCCTCAAATGTTTGCTCAGATTTGAGGGAAAGAGAAGTCA
AGGAAAGAAGCTCATTCTCTTGGATTAAGGGTTTGAATTAAAGCTTGATTTTGGAATTCAACCCTAATTTGAATTTTTCTGTTACATGATCTTGGTTTATCACAGATGGGAAGGGTAGAGAACTTTAA
GGAAATTAAGTAAAATTTTTAAAGTTAACATTTTCTTAGACTTCTTCAACCAACTGTCCTTTATTTTTCTATGAATCCCGAAATAGTTGTTTTCACCTCTTGAAATGAATATACAAATATAAACCAGC
TACTTGGTATAAATGAGAATTTGTGTGGGTATTTATTTAAATGACTTACACATATAATTCTGAGAGAATTTAAAATTACATTCAAATAAAATAATATGCTTATAGAATTTAAAAGAAAGTAGAAATTA
TTCCTCCAAGATTAACTGGTGGTTACTTGCAAATGAACTTCTCAGAATCTGTTACTCAAATAACTTTGGAAAACTGTATCGAGTAACTGAAATAAGTGTATATATGTAAAATATGGTTTCTAGTGAGA
TATGTGCCAAAGTCCATTTATCACCAAGTCCTGTCTGAAAGGAAGAGTGAGAGACATTGGTGTAAGCAGTTGGGAGAGCCAAAAGAGTAAAGTGGTCATTTCTACTTGGATAAAGTAAAAAATGTTCA
GTGTGTACAAAAGTGTTCTGTTTTTTCCACCCAGTGTTGTCTCATGTATAATAGAAAGTCCTAAAATTCTATTGGAGAGAAAATAATTTAGGTTGCTTGCTGCCTTATCAGCCTAAATATTTTTTTCC
ATTTTGTTACGATTTGCCTTTCTTCTTAGAGGAGGGGGAGTGGAGGGGAGGTGATATTCAGGATAATAAAAATGAATTTGGAACATCATAATTCCAGACTTTCTATTGAATTTATGTGTTTTAATAAA
TATTTGGAATTGTTTATGACTATTTAAAATAAATCTGACCAGTGTTTCCTTGTATATGTGTGGAGCAGCCCTCTGGAATTTAGGTCTTTCAGTGTGGAATCTATTTCTAAATGTTATTACATGGTGCA
CAAGTGACACTGCATATATTCCAGAATATTTCCCTTGCTGTATTATTATGAAAGCAGTACATTAAATTGATTTTTTGGTAATTAGTAATGTTAGCTTGAATTGAAGATTATGCAGAAGGAATAAGCTT
ATCACAAGGGACCATCAATCTGAGCCATGTCTGGTTCAAATACATAAAACTTCAAAGATAATTCATTCTTGGCAAATGCTTATATAGCTGTTGTTCCCTTGAAAGAAAAATAAAAGTTGTCTCCTAAT
AAAAATTATTCTGAATTAAAAATTAATCTGAGGTATAATCTAAATCTGGATTCAGTCTATTTCTCTTACCAGAATTGAAAGAAAAAAGTTAAAAGTTTTGCTGAAATTATTTAAAAATTAAACTGTTT
TCAGTGTGTCTTGTCTAATTTTTGATGAGTTGATAATTATTTTTCACATTAAATGATTAAAGCCAGAGATAGCTATA

hide sequence


Protein RefSeqs	XP_038330952	(Get FASTA)	NCBI Sequence Viewer
	XP_038392079	(Get FASTA)	NCBI Sequence Viewer
	XP_038456273	(Get FASTA)	NCBI Sequence Viewer
	XP_038520816	(Get FASTA)	NCBI Sequence Viewer
	XP_546524	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000020671.3
	ENSCAFP00000055186.1
	ENSCAFP00030020853.1
	ENSCAFP00030020933.1
	ENSCAFP00040009886.1
	ENSCAFP00040009945.1
	ENSCAFP00845002410
	ENSCAFP00845002410.1
	ENSCAFP00845002429.1

RefSeq Acc Id:

XP_546524 ⟸ XM_546524

- UniProtKB:

A0A8C0NAN7 (UniProtKB/TrEMBL), A0A8C0JYN1 (UniProtKB/TrEMBL), A0A8I3MZS6 (UniProtKB/TrEMBL), A0A8C0JZH9 (UniProtKB/TrEMBL), A0A8C0N8M9 (UniProtKB/TrEMBL), A0A8I3MGU8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MWRVCARRARNAAPRAGFAVRRAALREEPAAPRVTSRAGAAPARCSSGTAGSGGVRALCSGSLSSWATQRNRLLLQLLGSSGRRCYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKINEGELIAEV
ETDKATVGFESLEECYMAKILVAEGTRDVPVGAIICITVEKPEDIEAFKNYTLDSSAAPTPQAAAAPTPVAPTLPPTPPAQAPGSSYPTHMQVVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIE
TDKATIGFEVQEEGYLAKILIPEGTRDVPLGTPLCIIVEKEEDIPAFADYRPTEVTDLKPQAPPSTPPPVAPVPPTPQPVTPTPSAPRPATPAGPKGRLFASPLAKKLAAEKGIDLTQVKGTGPEGRI
IKKDVDSFVPTKAAPAPAAAVPAAVPGVAPVPSGVFTDVPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKMLEGRSKISVNDFIIKASALACLKVPEANSSWLDTVIRQNHVVDVS
VAVSTPAGLITPIVFNAHIKGLEAIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDRLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLE
KPITMLL

hide sequence

Ensembl Acc Id:

ENSCAFP00000055186 ⟸ ENSCAFT00000069257

Ensembl Acc Id:

ENSCAFP00000020671 ⟸ ENSCAFT00000022258

RefSeq Acc Id:

XP_038330952 ⟸ XM_038475024

RefSeq Acc Id:

XP_038456273 ⟸ XM_038600345

Protein Domains

Lipoyl-binding Peripheral subunit-binding (PSBD)

RGD ID:

Promoter ID:

Type:

initiation region

Name:

DLAT_1

Description:

dihydrolipoamide S-acetyltransferase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	21,094,199 - 21,094,259	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000014016	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030012864	UniProtKB/TrEMBL
	ENSCAFG00040006073	UniProtKB/TrEMBL
	ENSCAFG00845001723	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000022258.5	UniProtKB/TrEMBL
	ENSCAFT00000069257.2	UniProtKB/TrEMBL
	ENSCAFT00030023926.1	UniProtKB/TrEMBL
	ENSCAFT00030024013.1	UniProtKB/TrEMBL
	ENSCAFT00040011407.1	UniProtKB/TrEMBL
	ENSCAFT00040011470.1	UniProtKB/TrEMBL
	ENSCAFT00845003019	ENTREZGENE
	ENSCAFT00845003019.1	UniProtKB/TrEMBL
	ENSCAFT00845003043.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.100	UniProtKB/TrEMBL
	3.30.559.10	UniProtKB/TrEMBL
	4.10.320.10	UniProtKB/TrEMBL
InterPro	2-oxoA_DH_lipoyl-BS	UniProtKB/TrEMBL
	2-oxoacid_DH_actylTfrase	UniProtKB/TrEMBL
	Biotin_lipoyl	UniProtKB/TrEMBL
	CAT-like_dom_sf	UniProtKB/TrEMBL
	E2/Pdx1	UniProtKB/TrEMBL
	E3-bd_dom_sf	UniProtKB/TrEMBL
	LAT1	UniProtKB/TrEMBL
	PSBD	UniProtKB/TrEMBL
	Single_hybrid_motif	UniProtKB/TrEMBL
KEGG Report	cfa:489406	UniProtKB/TrEMBL
NCBI Gene	DLAT	ENTREZGENE
PANTHER	DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL	UniProtKB/TrEMBL
	PTHR23151	UniProtKB/TrEMBL
Pfam	2-oxoacid_dh	UniProtKB/TrEMBL
	Biotin_lipoyl	UniProtKB/TrEMBL
	E3_binding	UniProtKB/TrEMBL
PROSITE	BIOTINYL_LIPOYL	UniProtKB/TrEMBL
	LIPOYL	UniProtKB/TrEMBL
	PSBD	UniProtKB/TrEMBL
Superfamily-SCOP	CoA-dependent acyltransferases	UniProtKB/TrEMBL
	SSF47005	UniProtKB/TrEMBL
	SSF51230	UniProtKB/TrEMBL
UniProt	A0A8C0JYN1	ENTREZGENE
	A0A8C0JZH9	ENTREZGENE
	A0A8C0N8M9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0NAN7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MGU8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MZS6	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:39974	ENTREZGENE