PEX11A (peroxisomal biogenesis factor 11 alpha) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: PEX11A (peroxisomal biogenesis factor 11 alpha) Canis lupus familiaris
Analyze
Symbol: PEX11A
Name: peroxisomal biogenesis factor 11 alpha
RGD ID: 12330520
Description: ENCODES a protein that exhibits protein homodimerization activity (inferred); INVOLVED IN brown fat cell differentiation (ortholog); peroxisome membrane biogenesis (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); Chemical and Drug Induced Liver Injury (ortholog); colorectal cancer (ortholog); FOUND IN peroxisomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peroxisomal biogenesis factor 11A; peroxisomal membrane protein 11A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,674,363 - 52,684,776 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,674,348 - 52,684,660 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,308,322 - 55,318,739 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0353,090,753 - 53,101,172 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl353,090,755 - 53,101,151 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,612,919 - 52,623,332 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,824,121 - 52,833,237 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0353,163,246 - 53,173,666 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:17220199   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PEX11A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,674,363 - 52,684,776 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,674,348 - 52,684,660 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,308,322 - 55,318,739 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0353,090,753 - 53,101,172 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl353,090,755 - 53,101,151 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,612,919 - 52,623,332 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,824,121 - 52,833,237 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0353,163,246 - 53,173,666 (-)NCBIUU_Cfam_GSD_1.0
PEX11A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,681,535 - 89,690,754 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1589,677,764 - 89,690,783 (-)EnsemblGRCh38hg38GRCh38
GRCh371590,224,766 - 90,233,985 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361588,027,288 - 88,034,962 (-)NCBINCBI36Build 36hg18NCBI36
Build 341588,027,292 - 88,034,962NCBI
Celera1566,629,060 - 66,636,731 (-)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1566,337,719 - 66,346,969 (-)NCBIHuRef
CHM1_11590,065,595 - 90,074,847 (-)NCBICHM1_1
T2T-CHM13v2.01587,437,417 - 87,446,633 (-)NCBIT2T-CHM13v2.0
Pex11a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,385,705 - 79,392,879 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl779,385,705 - 79,392,879 (-)EnsemblGRCm39 Ensembl
GRCm38779,735,957 - 79,743,131 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,735,957 - 79,743,131 (-)EnsemblGRCm38mm10GRCm38
MGSCv37786,882,150 - 86,887,911 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,610,777 - 79,616,538 (-)NCBIMGSCv36mm8
Celera777,136,478 - 77,142,240 (-)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.12NCBI
Pex11a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81143,089,410 - 143,096,491 (-)NCBIGRCr8
mRatBN7.21133,680,091 - 133,687,172 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,680,091 - 133,687,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,589,549 - 141,596,507 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01148,758,938 - 148,765,910 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01141,676,644 - 141,683,616 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01141,474,189 - 141,481,270 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1141,474,180 - 141,481,315 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01142,435,410 - 142,442,491 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,513,735 - 135,520,816 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,593,304 - 135,685,129 (-)NCBI
Celera1125,743,709 - 125,750,790 (-)NCBICelera
Cytogenetic Map1q31NCBI
Pex11a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,527,941 - 15,534,424 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,527,925 - 15,537,497 (+)NCBIChiLan1.0ChiLan1.0
PEX11A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21679,231,159 - 79,240,431 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11582,936,655 - 82,945,276 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01568,375,201 - 68,384,440 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11587,581,581 - 87,590,684 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1587,581,564 - 87,590,684 (-)Ensemblpanpan1.1panPan2
Pex11a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640130,853,950 - 130,861,573 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648315,472,949 - 15,480,648 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648315,474,484 - 15,480,527 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEX11A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl755,256,220 - 55,264,247 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1755,256,239 - 55,264,253 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2760,145,337 - 60,153,336 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PEX11A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1298,220,082 - 8,229,448 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl298,221,920 - 8,229,243 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605938,584,059 - 38,593,190 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pex11a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476816,751,366 - 16,760,326 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476816,751,366 - 16,759,829 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PEX11A
167 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 1 22 6 6 5 12 8 9 6
Low 2 4 6 1 6 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000050066   ⟹   ENSCAFP00000041462
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl352,675,483 - 52,684,660 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000080905   ⟹   ENSCAFP00000059967
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl352,674,348 - 52,684,660 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845000721   ⟹   ENSCAFP00845000525
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl353,090,755 - 53,101,150 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845000733   ⟹   ENSCAFP00845000537
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl353,090,756 - 53,101,151 (-)Ensembl
RefSeq Acc Id: XM_003638962   ⟹   XP_003639010
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1352,674,363 - 52,684,776 (-)NCBI
Dog10K_Boxer_Tasha355,308,322 - 55,318,739 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005618358   ⟹   XP_005618415
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1352,674,363 - 52,684,763 (-)NCBI
Dog10K_Boxer_Tasha355,308,322 - 55,318,721 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038471913   ⟹   XP_038327841
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1352,612,919 - 52,623,332 (-)NCBI
RefSeq Acc Id: XM_038471914   ⟹   XP_038327842
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1352,612,919 - 52,623,314 (-)NCBI
RefSeq Acc Id: XM_038532844   ⟹   XP_038388772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0353,163,246 - 53,173,666 (-)NCBI
RefSeq Acc Id: XM_038532845   ⟹   XP_038388773
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0353,163,246 - 53,173,648 (-)NCBI
RefSeq Acc Id: XM_038597166   ⟹   XP_038453094
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0352,824,121 - 52,833,237 (-)NCBI
RefSeq Acc Id: XM_038597167   ⟹   XP_038453095
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0352,824,121 - 52,833,219 (-)NCBI
RefSeq Acc Id: XM_038661349   ⟹   XP_038517277
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0353,090,753 - 53,101,172 (-)NCBI
RefSeq Acc Id: XM_038661350   ⟹   XP_038517278
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0353,090,753 - 53,101,154 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005618415   ⟸   XM_005618358
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003639010   ⟸   XM_003638962
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L0V6 (UniProtKB/TrEMBL),   A0A8C0PWT5 (UniProtKB/TrEMBL),   A0A8I3RP55 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000041462   ⟸   ENSCAFT00000050066
RefSeq Acc Id: ENSCAFP00000059967   ⟸   ENSCAFT00000080905
RefSeq Acc Id: XP_038327841   ⟸   XM_038471913
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038327842   ⟸   XM_038471914
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038453094   ⟸   XM_038597166
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038453095   ⟸   XM_038597167
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038517277   ⟸   XM_038661349
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L0V6 (UniProtKB/TrEMBL),   A0A8C0PWT5 (UniProtKB/TrEMBL),   A0A8I3RP55 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038517278   ⟸   XM_038661350
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038388772   ⟸   XM_038532844
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L0V6 (UniProtKB/TrEMBL),   A0A8C0PWT5 (UniProtKB/TrEMBL),   A0A8I3RP55 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038388773   ⟸   XM_038532845
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCAFP00845000525   ⟸   ENSCAFT00845000721
RefSeq Acc Id: ENSCAFP00845000537   ⟸   ENSCAFT00845000733

Promoters
RGD ID:13682751
Promoter ID:EPDNEW_C817
Type:initiation region
Name:PEX11A_1
Description:peroxisomal biogenesis factor 11 alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1352,684,681 - 52,684,741EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000030217 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002578 UniProtKB/TrEMBL
  ENSCAFG00040001546 UniProtKB/TrEMBL
  ENSCAFG00845000454 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000050066.3 UniProtKB/TrEMBL
  ENSCAFT00000106085.1 UniProtKB/TrEMBL
  ENSCAFT00030004765.1 UniProtKB/TrEMBL
  ENSCAFT00030004770.1 UniProtKB/TrEMBL
  ENSCAFT00040002936.1 UniProtKB/TrEMBL
  ENSCAFT00040002942.1 UniProtKB/TrEMBL
  ENSCAFT00845000721.1 UniProtKB/TrEMBL
  ENSCAFT00845000733 ENTREZGENE
  ENSCAFT00845000733.1 UniProtKB/TrEMBL
InterPro PEX11 UniProtKB/TrEMBL
KEGG Report cfa:100856425 UniProtKB/TrEMBL
NCBI Gene PEX11A ENTREZGENE
PANTHER PEROXISOMAL BIOGENESIS FACTOR 11 UniProtKB/TrEMBL
  PEROXISOMAL MEMBRANE PROTEIN 11A UniProtKB/TrEMBL
Pfam PEX11 UniProtKB/TrEMBL
UniProt A0A8C0L0V6 ENTREZGENE
  A0A8C0PRI5_CANLF UniProtKB/TrEMBL
  A0A8C0PWT5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RP53_CANLF UniProtKB/TrEMBL
  A0A8I3RP55 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PH14_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:44426 ENTREZGENE