CPB2 (carboxypeptidase B2) - Rat Genome Database

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Gene: CPB2 (carboxypeptidase B2) Canis lupus familiaris
Analyze
Symbol: CPB2
Name: carboxypeptidase B2
RGD ID: 12118174
Description: ENCODES a protein that exhibits carboxypeptidase activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); fibrinolysis (ortholog); liver regeneration (ortholog); PARTICIPATES IN fibrinolysis pathway; ASSOCIATED WITH amenorrhea (ortholog); Angina Pectoris (ortholog); Bacteremia (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1225,074,805 - 5,126,635 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl225,074,816 - 5,126,170 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha225,060,946 - 5,113,389 (+)NCBI
ROS_Cfam_1.0225,190,115 - 5,242,228 (+)NCBI
UMICH_Zoey_3.1224,972,456 - 5,024,301 (+)NCBI
UNSW_CanFamBas_1.0225,035,678 - 5,087,765 (+)NCBI
UU_Cfam_GSD_1.0225,040,873 - 5,092,730 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
CPB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1225,074,805 - 5,126,635 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl225,074,816 - 5,126,170 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha225,060,946 - 5,113,389 (+)NCBI
ROS_Cfam_1.0225,190,115 - 5,242,228 (+)NCBI
UMICH_Zoey_3.1224,972,456 - 5,024,301 (+)NCBI
UNSW_CanFamBas_1.0225,035,678 - 5,087,765 (+)NCBI
UU_Cfam_GSD_1.0225,040,873 - 5,092,730 (+)NCBI
CPB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1346,053,186 - 46,105,033 (-)EnsemblGRCh38hg38GRCh38
GRCh381346,053,066 - 46,105,033 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371346,627,321 - 46,679,168 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361345,525,323 - 45,577,212 (-)NCBINCBI36hg18NCBI36
Build 341345,525,322 - 45,577,169NCBI
Celera1327,682,037 - 27,734,241 (-)NCBI
Cytogenetic Map13q14.13NCBI
HuRef1327,424,287 - 27,477,016 (-)NCBIHuRef
CHM1_11346,596,461 - 46,648,341 (-)NCBICHM1_1
Cpb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391475,479,727 - 75,520,995 (+)NCBIGRCm39mm39
GRCm39 Ensembl1475,479,727 - 75,520,995 (+)Ensembl
GRCm381475,242,287 - 75,283,555 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1475,242,287 - 75,283,555 (+)EnsemblGRCm38mm10GRCm38
MGSCv371475,642,094 - 75,683,362 (+)NCBIGRCm37mm9NCBIm37
MGSCv361473,976,443 - 74,017,701 (+)NCBImm8
Celera1472,744,408 - 72,785,554 (+)NCBICelera
Cytogenetic Map14D3NCBI
Cpb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21550,557,722 - 50,606,569 (+)NCBI
Rnor_6.0 Ensembl1557,290,849 - 57,339,760 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01557,290,849 - 57,339,762 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01561,001,889 - 61,050,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41556,104,920 - 56,154,321 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11556,120,686 - 56,170,027 (+)NCBI
Celera1550,189,675 - 50,237,544 (+)NCBICelera
Cytogenetic Map15q11NCBI
Cpb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555183,740,348 - 3,803,539 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555183,740,348 - 3,803,540 (-)NCBIChiLan1.0ChiLan1.0
CPB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v01326,926,788 - 26,979,767 (+)NCBIMhudiblu_PPA_v0panPan3
Cpb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945156,155,086 - 156,203,983 (-)NCBI
SpeTri2.0NW_004936857577,067 - 609,855 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1121,234,447 - 21,298,244 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11121,234,447 - 21,298,250 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21121,696,077 - 21,757,686 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CPB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1324,108,854 - 24,161,669 (-)NCBI
ChlSab1.1 Ensembl324,109,416 - 24,161,408 (-)Ensembl
Vero_WHO_p1.0NW_02366605719,855,294 - 19,907,245 (+)NCBI
Cpb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247488,850,128 - 8,927,986 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 6 6
Low 6 2
Below cutoff 3 5 7 4 2 1 7 2 6 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000007266   ⟹   ENSCAFP00000006731
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl225,074,816 - 5,126,105 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000071461   ⟹   ENSCAFP00000061497
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl225,074,816 - 5,126,170 (+)Ensembl
RefSeq Acc Id: XM_038430969   ⟹   XP_038286897
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0225,190,115 - 5,242,228 (+)NCBI
RefSeq Acc Id: XM_038506350   ⟹   XP_038362278
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1224,972,456 - 5,024,301 (+)NCBI
RefSeq Acc Id: XM_038569551   ⟹   XP_038425479
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0225,040,873 - 5,092,730 (+)NCBI
RefSeq Acc Id: XM_038633716   ⟹   XP_038489644
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0225,035,678 - 5,087,765 (+)NCBI
RefSeq Acc Id: XM_846061   ⟹   XP_851154
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1225,074,805 - 5,126,635 (+)NCBI
Dog10K_Boxer_Tasha225,060,946 - 5,113,389 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038286897 (Get FASTA)   NCBI Sequence Viewer  
  XP_038362278 (Get FASTA)   NCBI Sequence Viewer  
  XP_038425479 (Get FASTA)   NCBI Sequence Viewer  
  XP_038489644 (Get FASTA)   NCBI Sequence Viewer  
  XP_851154 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_851154   ⟸   XM_846061
- UniProtKB: E2RN74 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000061497   ⟸   ENSCAFT00000071461
RefSeq Acc Id: ENSCAFP00000006731   ⟸   ENSCAFT00000007266
RefSeq Acc Id: XP_038362278   ⟸   XM_038506350
RefSeq Acc Id: XP_038489644   ⟸   XM_038633716
RefSeq Acc Id: XP_038286897   ⟸   XM_038430969
RefSeq Acc Id: XP_038425479   ⟸   XM_038569551
Protein Domains
Peptidase_M14

Promoters
RGD ID:13687302
Promoter ID:EPDNEW_C5370
Type:initiation region
Name:CPB2_1
Description:carboxypeptidase B2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1225,074,800 - 5,074,860EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004499 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000006731 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000061497 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000007266 UniProtKB/TrEMBL
  ENSCAFT00000071461 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.340 UniProtKB/TrEMBL
InterPro CPB2 UniProtKB/TrEMBL
  M14A-like_propep UniProtKB/TrEMBL
  M14A_act_pep UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
KEGG Report cfa:608910 UniProtKB/TrEMBL
NCBI Gene CPB2 ENTREZGENE
Pfam Peptidase_M14 UniProtKB/TrEMBL
  Propep_M14 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
SMART Zn_pept UniProtKB/TrEMBL
UniProt A0A5F4D6V1_CANLF UniProtKB/TrEMBL
  E2RN74 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:39550 ENTREZGENE