CA3 (carbonic anhydrase 3) - Rat Genome Database

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Gene: CA3 (carbonic anhydrase 3) Canis lupus familiaris
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Symbol: CA3
Name: carbonic anhydrase 3
RGD ID: 12402456
Description: ENCODES a protein that exhibits phosphatase activity (ortholog); INVOLVED IN response to bacterium (ortholog); response to ethanol (ortholog); response to oxidative stress (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Experimental Liver Cirrhosis (ortholog); Experimental Liver Neoplasms (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH phenobarbital
Type: protein-coding
RefSeq Status: INFERRED
Also known as: carbonic anhydrase III, muscle specific
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12931,935,192 - 31,945,585 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2931,935,172 - 31,980,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02932,083,862 - 32,094,321 (+)NCBI
UMICH_Zoey_3.12932,135,278 - 32,145,713 (+)NCBI
UNSW_CanFamBas_1.02932,156,474 - 32,166,928 (+)NCBI
UU_Cfam_GSD_1.02932,543,269 - 32,553,756 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
CA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12931,935,192 - 31,945,585 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2931,935,172 - 31,980,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02932,083,862 - 32,094,321 (+)NCBI
UMICH_Zoey_3.12932,135,278 - 32,145,713 (+)NCBI
UNSW_CanFamBas_1.02932,156,474 - 32,166,928 (+)NCBI
UU_Cfam_GSD_1.02932,543,269 - 32,553,756 (+)NCBI
CA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl885,373,436 - 85,449,040 (+)EnsemblGRCh38hg38GRCh38
GRCh38885,438,859 - 85,449,040 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37886,351,088 - 86,361,269 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36886,537,710 - 86,548,526 (+)NCBINCBI36hg18NCBI36
Build 34886,537,709 - 86,548,526NCBI
Celera882,356,136 - 82,366,348 (+)NCBI
Cytogenetic Map8q21.2NCBI
HuRef881,845,249 - 81,855,461 (+)NCBIHuRef
CHM1_1886,402,742 - 86,412,955 (+)NCBICHM1_1
Car3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39314,928,598 - 14,937,441 (+)NCBIGRCm39mm39
GRCm39 Ensembl314,928,572 - 14,937,583 (+)Ensembl
GRCm38314,863,538 - 14,872,381 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl314,863,512 - 14,872,523 (+)EnsemblGRCm38mm10GRCm38
MGSCv37314,863,538 - 14,872,381 (+)NCBIGRCm37mm9NCBIm37
MGSCv36314,840,282 - 14,849,125 (+)NCBImm8
Celera314,876,182 - 14,885,071 (+)NCBICelera
Cytogenetic Map3A1NCBI
cM Map33.22NCBI
Ca3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2286,770,418 - 86,780,011 (-)NCBI
Rnor_6.0 Ensembl288,126,667 - 88,135,410 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0288,126,519 - 88,136,063 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02107,900,433 - 107,909,977 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4288,106,727 - 88,114,686 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1288,050,843 - 88,059,683 (-)NCBI
Celera282,369,065 - 82,377,024 (-)NCBICelera
Cytogenetic Map2q23NCBI
Ca3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554173,362,492 - 3,372,932 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554173,362,091 - 3,372,270 (+)NCBIChiLan1.0ChiLan1.0
CA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1883,574,931 - 83,585,737 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0881,965,041 - 81,976,133 (+)NCBIMhudiblu_PPA_v0panPan3
Ca3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530347,444,945 - 47,454,991 (-)NCBI
SpeTri2.0NW_004936544337,437 - 347,760 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl451,219,736 - 51,237,846 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1451,227,485 - 51,237,861 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2456,190,405 - 56,200,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CA3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1880,805,296 - 80,816,127 (+)NCBI
ChlSab1.1 Ensembl880,805,134 - 80,816,190 (+)Ensembl
Ca3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247446,202,151 - 6,211,662 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 10 2 6 2 1 6 12 8 5
Low 2 5 12 4 4 5 5 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: NM_001145172   ⟹   NP_001138644
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12931,935,192 - 31,945,585 (+)NCBI
ROS_Cfam_1.02932,083,862 - 32,094,321 (+)NCBI
UMICH_Zoey_3.12932,135,278 - 32,145,713 (+)NCBI
UNSW_CanFamBas_1.02932,156,474 - 32,166,928 (+)NCBI
UU_Cfam_GSD_1.02932,543,269 - 32,553,756 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001138644 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001138644   ⟸   NM_001145172
- UniProtKB: F1PDZ7 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Alpha-carbonic anhydrase

Promoters
RGD ID:13688445
Promoter ID:EPDNEW_C6513
Type:single initiation site
Name:CA3_1
Description:carbonic anhydrase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12931,935,179 - 31,935,239EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000025202 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000012748 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000043886 UniProtKB/TrEMBL
  ENSCAFP00000045502 UniProtKB/TrEMBL
  ENSCAFP00000053489 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000013785 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFT00000080967 UniProtKB/TrEMBL
  ENSCAFT00000082253 UniProtKB/TrEMBL
  ENSCAFT00000082360 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro Carbonic_anhydrase_a UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
  Carbonic_anhydrase_a_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_CA3 UniProtKB/TrEMBL
KEGG Report cfa:487032 UniProtKB/TrEMBL
NCBI Gene CA3 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF127 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A5F4BSH6_CANLF UniProtKB/TrEMBL
  A0A5F4BUI1_CANLF UniProtKB/TrEMBL
  A0A5F4CJB2_CANLF UniProtKB/TrEMBL
  F1PDZ7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38611 ENTREZGENE