NTN1 (netrin 1) - Rat Genome Database

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Gene: NTN1 (netrin 1) Canis lupus familiaris
Analyze
Symbol: NTN1
Name: netrin 1
RGD ID: 12084785
Description: INVOLVED IN anterior/posterior axon guidance (ortholog); axon guidance (ortholog); axonogenesis (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); brain edema (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN glutamatergic synapse (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: netrin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,654,723 - 33,825,832 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,637,142 - 33,825,899 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,791,096 - 33,962,030 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,758,267 - 33,929,266 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,757,152 - 33,929,220 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,725,541 - 33,896,204 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,683,225 - 33,853,961 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,859,633 - 34,030,422 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
NTN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,654,723 - 33,825,832 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,637,142 - 33,825,899 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,791,096 - 33,962,030 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,758,267 - 33,929,266 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,757,152 - 33,929,220 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,725,541 - 33,896,204 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,683,225 - 33,853,961 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,859,633 - 34,030,422 (+)NCBIUU_Cfam_GSD_1.0
NTN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38179,003,087 - 9,244,000 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl179,021,510 - 9,244,000 (+)EnsemblGRCh38hg38GRCh38
GRCh37178,924,827 - 9,147,317 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,865,584 - 9,088,042 (+)NCBINCBI36Build 36hg18NCBI36
Build 34178,865,583 - 9,084,078NCBI
Celera178,956,718 - 9,179,095 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef178,823,748 - 9,046,260 (+)NCBIHuRef
CHM1_1178,934,056 - 9,156,348 (+)NCBICHM1_1
T2T-CHM13v2.0178,910,268 - 9,150,998 (+)NCBIT2T-CHM13v2.0
Ntn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,100,190 - 68,277,652 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,100,190 - 68,291,649 (-)EnsemblGRCm39 Ensembl
GRCm381168,209,364 - 68,386,826 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,209,364 - 68,400,823 (-)EnsemblGRCm38mm10GRCm38
MGSCv371168,022,866 - 68,200,328 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,029,201 - 68,202,315 (-)NCBIMGSCv36mm8
Celera1175,146,897 - 75,324,142 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1141.45NCBI
Ntn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81053,398,852 - 53,597,595 (-)NCBIGRCr8
mRatBN7.21052,899,933 - 53,098,591 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1052,899,934 - 53,085,326 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1057,569,983 - 57,744,352 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,059,000 - 57,233,370 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01052,559,808 - 52,740,213 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01054,761,925 - 54,982,072 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1054,761,871 - 54,967,585 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01054,507,464 - 54,725,989 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41054,950,521 - 55,133,536 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11054,964,143 - 55,147,159 (-)NCBI
Celera1052,078,465 - 52,253,812 (-)NCBICelera
Cytogenetic Map10q24NCBI
Ntn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554677,794,735 - 7,991,695 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554677,795,175 - 7,991,597 (-)NCBIChiLan1.0ChiLan1.0
NTN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21964,503,878 - 64,726,212 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11769,313,754 - 69,536,000 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01742,409,797 - 42,631,930 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11747,148,384 - 47,368,127 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1747,152,225 - 47,368,134 (-)Ensemblpanpan1.1panPan2
Ntn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560248,672,178 - 48,849,151 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365952,146,366 - 2,323,399 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365952,146,371 - 2,323,346 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NTN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1254,089,472 - 54,292,193 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11254,089,444 - 54,292,191 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21256,822,597 - 57,056,391 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NTN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1168,359,682 - 8,603,231 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl168,379,129 - 8,603,223 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605912,748,497 - 13,022,123 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ntn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478611,526,050 - 11,703,258 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478611,508,643 - 11,707,060 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NTN1
1782 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000027580   ⟹   ENSCAFP00000025650
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl533,637,142 - 33,825,899 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000027581   ⟹   ENSCAFP00000025651
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl533,637,142 - 33,825,899 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845002263   ⟹   ENSCAFP00845001791
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl533,757,152 - 33,929,220 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845002275   ⟹   ENSCAFP00845001801
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl533,757,152 - 33,929,220 (+)Ensembl
RefSeq Acc Id: XM_038475681   ⟹   XP_038331609
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1533,725,541 - 33,896,204 (+)NCBI
RefSeq Acc Id: XM_038536860   ⟹   XP_038392788
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0533,859,633 - 34,030,422 (+)NCBI
RefSeq Acc Id: XM_038601011   ⟹   XP_038456939
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0533,683,225 - 33,853,961 (+)NCBI
RefSeq Acc Id: XM_038665579   ⟹   XP_038521507
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0533,758,267 - 33,929,266 (+)NCBI
RefSeq Acc Id: XM_845211   ⟹   XP_850304
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1533,654,723 - 33,825,832 (+)NCBI
Dog10K_Boxer_Tasha533,791,096 - 33,962,030 (+)NCBI
Sequence:
RefSeq Acc Id: XP_850304   ⟸   XM_845211
- UniProtKB: A0A8C0K1V0 (UniProtKB/TrEMBL),   A0A8C0LYS4 (UniProtKB/TrEMBL),   A0A8I3MFH5 (UniProtKB/TrEMBL),   A0A8I3MDJ9 (UniProtKB/TrEMBL),   A0A8P0SLN8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000025651   ⟸   ENSCAFT00000027581
Ensembl Acc Id: ENSCAFP00000025650   ⟸   ENSCAFT00000027580
RefSeq Acc Id: XP_038331609   ⟸   XM_038475681
RefSeq Acc Id: XP_038456939   ⟸   XM_038601011
RefSeq Acc Id: XP_038521507   ⟸   XM_038665579
- UniProtKB: A0A8C0K1V0 (UniProtKB/TrEMBL),   A0A8C0LYS4 (UniProtKB/TrEMBL),   A0A8I3MFH5 (UniProtKB/TrEMBL),   A0A8I3MDJ9 (UniProtKB/TrEMBL),   A0A8P0SLN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392788   ⟸   XM_038536860
- UniProtKB: A0A8I3MDJ9 (UniProtKB/TrEMBL),   A0A8P0SLN8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845001801   ⟸   ENSCAFT00845002275
Ensembl Acc Id: ENSCAFP00845001791   ⟸   ENSCAFT00845002263
Protein Domains
Laminin EGF-like   Laminin N-terminal   NTR

Promoters
RGD ID:13683249
Promoter ID:EPDNEW_C1315
Type:single initiation site
Name:NTN1_1
Description:netrin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_C1316  
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1533,654,657 - 33,654,717EPDNEW
RGD ID:13683248
Promoter ID:EPDNEW_C1316
Type:single initiation site
Name:NTN1_2
Description:netrin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_C1315  
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1533,654,785 - 33,654,845EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017403 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000945 UniProtKB/TrEMBL
  ENSCAFG00845001314 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027580.6 UniProtKB/TrEMBL
  ENSCAFT00000027581.5 UniProtKB/TrEMBL
  ENSCAFT00030001618.1 UniProtKB/TrEMBL
  ENSCAFT00845002263 ENTREZGENE
  ENSCAFT00845002263.1 UniProtKB/TrEMBL
  ENSCAFT00845002275.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.120 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro Galactose-bd-like_sf UniProtKB/TrEMBL
  Laminin/Netrin_ECM UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
  LE_dom UniProtKB/TrEMBL
  Netrin_domain UniProtKB/TrEMBL
  Netrin_module_non-TIMP UniProtKB/TrEMBL
  TIMP-like_OB-fold UniProtKB/TrEMBL
NCBI Gene NTN1 ENTREZGENE
PANTHER LAMININ SUBUNIT GAMMA-1 UniProtKB/TrEMBL
  NETRIN-1 UniProtKB/TrEMBL
  NETRIN/LAMININ-RELATED UniProtKB/TrEMBL
Pfam Laminin_EGF UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
  NTR UniProtKB/TrEMBL
PROSITE EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  LAMININ_NTER UniProtKB/TrEMBL
  NTR UniProtKB/TrEMBL
SMART C345C UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  LamNT UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF49785 UniProtKB/TrEMBL
  SSF50242 UniProtKB/TrEMBL
UniProt A0A8C0K1V0 ENTREZGENE
  A0A8C0LYS4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MDJ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MFH5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SLN8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44007 ENTREZGENE