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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine
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Accession:CHEBI:88217 term browser browse the term
Definition:An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
Synonyms:exact_synonym: N(1),N(1),N(2),N(2)-tetrakis[(pyridin-2-yl)methyl]ethane-1,2-diamine
 related_synonym: Formula=C26H28N6;   InChI=1S/C26H28N6/c1-5-13-27-23(9-1)19-31(20-24-10-2-6-14-28-24)17-18-32(21-25-11-3-7-15-29-25)22-26-12-4-8-16-30-26/h1-16H,17-22H2;   InChIKey=CVRXLMUYFMERMJ-UHFFFAOYSA-N;   SMILES=C(CN(CC1=NC=CC=C1)CC2=NC=CC=C2)N(CC3=NC=CC=C3)CC4=NC=CC=C4;   TPEN
 xref: CAS:16858-02-9;   LINCS:LSM-19976
 xref_mesh: MESH:C044387
 xref: PMID:22225878;   PMID:25667569;   PMID:25813624;   PMID:25973665;   PMID:26004891;   PMID:26143360;   PMID:26190227;   Reaxys:4211982



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N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS1 alanyl-tRNA synthetase 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of AARS1 mRNA CTD PMID:19013360 NCBI chr16:70,252,298...70,289,506
Ensembl chr16:70,251,983...70,289,707
JBrowse link
G ABCC10 ATP binding cassette subfamily C member 10 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ABCC10 mRNA CTD PMID:12756304 NCBI chr 6:43,427,541...43,451,994
Ensembl chr 6:43,427,366...43,450,430
JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of ABCC9 mRNA CTD PMID:12756304 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ABL1 mRNA CTD PMID:12756304 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675
JBrowse link
G ACADL acyl-CoA dehydrogenase long chain decreases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ACADL protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ACADL protein]
CTD PMID:19637192 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447
JBrowse link
G AGT angiotensinogen multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [AGT protein results in decreased expression of CAT protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [AGT protein results in increased localization of Zinc] CTD PMID:22427991 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] affects the localization of AIFM1 protein] CTD PMID:18951928 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of ALPL mRNA CTD PMID:19913120 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
JBrowse link
G AP2B1 adaptor related protein complex 2 subunit beta 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of AP2B1 mRNA CTD PMID:12756304 NCBI chr17:35,587,322...35,726,413
Ensembl chr17:35,578,046...35,726,413
JBrowse link
G APC2 APC regulator of WNT signaling pathway 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of APC2 mRNA CTD PMID:12756304 NCBI chr19:1,446,230...1,473,244
Ensembl chr19:1,446,302...1,473,244
JBrowse link
G APOB apolipoprotein B decreases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of APOB protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of APOB protein]
CTD PMID:19637192 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G ARHGEF18 Rho/Rac guanine nucleotide exchange factor 18 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ARHGEF18 mRNA CTD PMID:12756304 NCBI chr19:7,348,937...7,479,989
Ensembl chr19:7,348,937...7,472,485
JBrowse link
G ATM ATM serine/threonine kinase increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of ATM mRNA CTD PMID:33645215 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102
JBrowse link
G AZIN1 antizyme inhibitor 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of AZIN1 mRNA CTD PMID:12756304 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,111...102,893,864
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]] CTD PMID:19887557 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BBC3 mRNA CTD PMID:12756304 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BBS9 Bardet-Biedl syndrome 9 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of BBS9 mRNA CTD PMID:12756304 NCBI chr 7:33,129,285...33,635,767
Ensembl chr 7:33,109,557...33,877,180
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BCL2 mRNA
CTD PMID:19887557 PMID:33645215 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]] CTD PMID:19887557 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of BGLAP protein
[zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of BGLAP mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of BGLAP mRNA
CTD PMID:19913120 PMID:22228435 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BRCA2 BRCA2 DNA repair associated increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of BRCA2 mRNA CTD PMID:33645215 NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G BRD1 bromodomain containing 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BRD1 mRNA CTD PMID:12756304 NCBI chr22:49,773,278...49,827,873
Ensembl chr22:49,773,278...49,827,873
JBrowse link
G BRD3 bromodomain containing 3 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BRD3 mRNA CTD PMID:12756304 NCBI chr 9:134,030,305...134,068,548
Ensembl chr 9:134,030,305...134,068,535
JBrowse link
G BRD8 bromodomain containing 8 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BRD8 mRNA CTD PMID:12756304 NCBI chr 5:138,139,770...138,178,630
Ensembl chr 5:138,139,770...138,178,953
JBrowse link
G C1orf50 chromosome 1 open reading frame 50 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of C1ORF50 mRNA CTD PMID:12756304 NCBI chr 1:42,767,249...42,779,491
Ensembl chr 1:42,767,245...42,779,491
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H multiple interactions ISO 3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein CTD PMID:29129814 NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169
JBrowse link
G CAMSAP1 calmodulin regulated spectrin associated protein 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CAMSAP1 mRNA CTD PMID:12756304 NCBI chr 9:135,808,487...135,907,546
Ensembl chr 9:135,808,487...135,907,546
JBrowse link
G CASP1 caspase 1 increases expression
multiple interactions
EXP
ISO
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CASP1 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]
CTD PMID:17622302 PMID:19130485 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
increases activity
decreases expression
EXP [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased activity of CASP3 protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CASP3 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of CASP3 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CASP3 mRNA
CTD PMID:15966574 PMID:16844947 PMID:17169355 PMID:17979179 PMID:18778698 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 increases activity EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of CASP8 protein CTD PMID:17979179 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 increases activity EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of CASP9 protein CTD PMID:17169355 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [AGT protein results in decreased expression of CAT protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CAT protein
CTD PMID:22427991 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCL2 mRNA CTD PMID:19013360 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL22 C-C motif chemokine ligand 22 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCL22 mRNA CTD PMID:19013360 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189
JBrowse link
G CCL3 C-C motif chemokine ligand 3 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCL3 mRNA CTD PMID:19013360 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCND1 cyclin D1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCND1 mRNA CTD PMID:12756304 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCR1 C-C motif chemokine receptor 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCR1 mRNA CTD PMID:19013360 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313
JBrowse link
G CCR2 C-C motif chemokine receptor 2 decreases expression
increases expression
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CCR2 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCR2 mRNA
CTD PMID:12756304 PMID:19013360 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CD14 CD14 molecule multiple interactions
increases expression
EXP [Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD14 protein]; parthenolide promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]; pyrithione promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CD14 protein
CTD PMID:20089671 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
JBrowse link
G CD58 CD58 molecule decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CD58 mRNA CTD PMID:12756304 NCBI chr 1:116,514,534...116,571,026
Ensembl chr 1:116,514,534...116,571,039
JBrowse link
G CD86 CD86 molecule increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CD86 protein CTD PMID:16892068 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDH1 cadherin 1 multiple interactions EXP [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein] CTD PMID:16844947 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CDKN1A mRNA CTD PMID:33645215 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397
JBrowse link
G CEBPD CCAAT enhancer binding protein delta decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CEBPD mRNA CTD PMID:12756304 NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164
JBrowse link
G CFP complement factor properdin increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CFP mRNA CTD PMID:19013360 NCBI chr  X:47,623,282...47,630,305
Ensembl chr  X:47,623,172...47,630,305
JBrowse link
G CLCN7 chloride voltage-gated channel 7 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CLCN7 mRNA CTD PMID:12756304 NCBI chr16:1,444,935...1,475,028
Ensembl chr16:1,444,934...1,475,077
JBrowse link
G CLCNKB chloride voltage-gated channel Kb increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CLCNKB mRNA CTD PMID:12756304 NCBI chr 1:16,043,782...16,057,326
Ensembl chr 1:16,040,252...16,057,311
JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of COL1A1 mRNA CTD PMID:19913120 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G CREBBP CREB binding protein multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [HIF1A protein binds to CREBBP protein] CTD PMID:16579968 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CRYZ crystallin zeta decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CRYZ mRNA CTD PMID:12888634 NCBI chr 1:74,705,486...74,733,050
Ensembl chr 1:74,705,482...74,733,408
JBrowse link
G CTDP1 CTD phosphatase subunit 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CTDP1 mRNA CTD PMID:12756304 NCBI chr18:79,676,768...79,756,625
Ensembl chr18:79,679,803...79,754,503
JBrowse link
G CTDSP2 CTD small phosphatase 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CTDSP2 mRNA CTD PMID:12756304 NCBI chr12:57,819,927...57,846,729
Ensembl chr12:57,819,927...57,846,729
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein] CTD PMID:16844947 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CTSD cathepsin D multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Ethambutol results in increased expression of and affects the localization of CTSD protein] CTD PMID:19063910 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
JBrowse link
G CTSK cathepsin K increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CTSK mRNA CTD PMID:19013360 NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,794,880...150,809,577
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CX3CR1 mRNA CTD PMID:19013360 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CXCL2 mRNA CTD PMID:19013360 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases secretion
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased secretion of CXCL8 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Particulate Matter results in increased expression of CXCL8 protein]
CTD PMID:18615482 PMID:26303504 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYTH4 cytohesin 4 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CYTH4 mRNA CTD PMID:12756304 NCBI chr22:37,282,508...37,315,341
Ensembl chr22:37,282,027...37,315,341
JBrowse link
G DAD1 defender against cell death 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DAD1 mRNA CTD PMID:12888634 NCBI chr14:22,564,907...22,589,224
Ensembl chr14:22,564,907...22,589,224
JBrowse link
G DDX23 DEAD-box helicase 23 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DDX23 mRNA CTD PMID:12756304 NCBI chr12:48,829,756...48,852,163
Ensembl chr12:48,829,756...48,852,842
JBrowse link
G DGCR2 DiGeorge syndrome critical region gene 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DGCR2 mRNA CTD PMID:12756304 NCBI chr22:19,036,286...19,122,412
Ensembl chr22:19,036,282...19,122,454
JBrowse link
G DGKZ diacylglycerol kinase zeta decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DGKZ mRNA CTD PMID:12756304 NCBI chr11:46,332,926...46,380,554
Ensembl chr11:46,332,905...46,380,554
JBrowse link
G DHX58 DExH-box helicase 58 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of DHX58 mRNA CTD PMID:12756304 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714
JBrowse link
G DICER1 dicer 1, ribonuclease III decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DICER1 mRNA CTD PMID:12756304 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010
JBrowse link
G DSPP dentin sialophosphoprotein multiple interactions
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [NFIC protein binds to DSPP promoter]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of DSPP mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of DSPP protein
CTD PMID:22228435 NCBI chr 4:87,608,529...87,616,873
Ensembl chr 4:87,608,529...87,616,873
JBrowse link
G DSTN destrin, actin depolymerizing factor increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of DSTN mRNA CTD PMID:12756304 NCBI chr20:17,570,075...17,609,919
Ensembl chr20:17,570,075...17,609,919
JBrowse link
G DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DYNC1LI2 mRNA CTD PMID:12756304 NCBI chr16:66,720,893...66,751,609
Ensembl chr16:66,720,893...66,751,609
JBrowse link
G E2F1 E2F transcription factor 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of E2F1 mRNA CTD PMID:33645215 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
JBrowse link
G EEF1AKMT2 EEF1A lysine methyltransferase 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of EEF1AKMT2 mRNA CTD PMID:19013360 NCBI chr10:124,756,253...124,791,887
Ensembl chr10:124,748,149...124,791,887
JBrowse link
G EGFL7 EGF like domain multiple 7 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of EGFL7 mRNA CTD PMID:12756304 NCBI chr 9:136,658,856...136,672,678
Ensembl chr 9:136,658,856...136,672,678
JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 increases activity
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein
zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein]
CTD PMID:16579968 PMID:16973622 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287
JBrowse link
G EGR1 early growth response 1 multiple interactions ISO 3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein CTD PMID:29129814 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EHD1 EH domain containing 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of EHD1 mRNA CTD PMID:12756304 NCBI chr11:64,851,642...64,879,693
Ensembl chr11:64,851,642...64,888,296
JBrowse link
G ELF4 E74 like ETS transcription factor 4 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ELF4 mRNA CTD PMID:12756304 NCBI chr  X:130,063,955...130,111,927
Ensembl chr  X:130,063,955...130,110,716
JBrowse link
G ESS2 ess-2 splicing factor homolog decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ESS2 mRNA CTD PMID:12756304 NCBI chr22:19,130,279...19,144,651
Ensembl chr22:19,130,279...19,144,684
JBrowse link
G FADD Fas associated via death domain decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of FADD mRNA CTD PMID:12756304 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390
JBrowse link
G FAM13A family with sequence similarity 13 member A increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of FAM13A mRNA CTD PMID:12756304 NCBI chr 4:88,725,960...89,057,185
Ensembl chr 4:88,725,955...89,111,398
JBrowse link
G FCER1A Fc epsilon receptor Ia multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of PRKCB protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of IL6 mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of IL6 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of TNF mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of TNF protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased phosphorylation of IKBKB protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]] CTD PMID:16818790 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224
JBrowse link
G FEZ1 fasciculation and elongation protein zeta 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of FEZ1 mRNA CTD PMID:12756304 NCBI chr11:125,442,881...125,496,265
Ensembl chr11:125,442,881...125,592,568
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased expression of FOS mRNA] CTD PMID:20201035 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
JBrowse link
G FOXO3 forkhead box O3 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of FOXO3 mRNA CTD PMID:12756304 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G FRAT2 FRAT regulator of WNT signaling pathway 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of FRAT2 mRNA CTD PMID:12756304 NCBI chr10:97,332,497...97,334,729
Ensembl chr10:97,332,497...97,334,729
JBrowse link
G FZR1 fizzy and cell division cycle 20 related 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of FZR1 mRNA CTD PMID:12756304 NCBI chr19:3,506,311...3,538,334
Ensembl chr19:3,506,311...3,538,334
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of G6PD mRNA CTD PMID:12888634 PMID:17018880 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of GADD45A mRNA CTD PMID:33645215 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GATA1 GATA binding protein 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [GATA1 protein binds to ZFPM1 protein] CTD PMID:33149232 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,540...48,794,311
JBrowse link
G GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GGA2 mRNA CTD PMID:12756304 NCBI chr16:23,463,542...23,524,359
Ensembl chr16:23,462,213...23,521,995
JBrowse link
G GMIP GEM interacting protein decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GMIP mRNA CTD PMID:12756304 NCBI chr19:19,629,476...19,643,657
Ensembl chr19:19,629,476...19,643,657
JBrowse link
G GOLPH3L golgi phosphoprotein 3 like decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GOLPH3L mRNA CTD PMID:12756304 NCBI chr 1:150,646,230...150,697,154
Ensembl chr 1:150,646,230...150,697,154
JBrowse link
G GORASP2 golgi reassembly stacking protein 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GORASP2 mRNA CTD PMID:12756304 NCBI chr 2:170,928,477...170,967,130
Ensembl chr 2:170,928,464...170,967,130
JBrowse link
G GSTA1 glutathione S-transferase alpha 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GSTA1 mRNA CTD PMID:17018880 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860
JBrowse link
G H1-2 H1.2 linker histone, cluster member increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H1-2 mRNA CTD PMID:19013360 NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,054,760...26,056,470
JBrowse link
G H1-3 H1.3 linker histone, cluster member increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H1-3 mRNA CTD PMID:19013360 NCBI chr 6:26,234,212...26,234,987
Ensembl chr 6:26,234,212...26,234,987
JBrowse link
G H2AC18 H2A clustered histone 18 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2AC18 mRNA CTD PMID:19013360 NCBI chr 1:149,842,218...149,842,750
Ensembl chr 1:149,842,218...149,842,750
JBrowse link
G H2BC12 H2B clustered histone 12 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2BC12 mRNA CTD PMID:19013360 NCBI chr 6:27,138,293...27,146,858
Ensembl chr 6:27,137,298...27,146,855
JBrowse link
G H2BC14 H2B clustered histone 14 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2BC14 mRNA CTD PMID:19013360 NCBI chr 6:27,815,022...27,815,489
Ensembl chr 6:27,815,022...27,815,489
JBrowse link
G H2BC21 H2B clustered histone 21 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2BC21 mRNA CTD PMID:19013360 NCBI chr 1:149,884,459...149,886,682
Ensembl chr 1:149,884,459...149,886,682
JBrowse link
G H2BC5 H2B clustered histone 5 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2BC5 mRNA CTD PMID:19013360 NCBI chr 6:26,158,121...26,171,349
Ensembl chr 6:26,158,122...26,171,349
JBrowse link
G H2BC6 H2B clustered histone 6 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2BC6 mRNA CTD PMID:19013360 NCBI chr 6:26,183,761...26,184,230
Ensembl chr 6:26,172,059...26,184,655
JBrowse link
G H2BC9 H2B clustered histone 9 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2BC9 mRNA CTD PMID:19013360 NCBI chr 6:26,251,614...26,252,075
Ensembl chr 6:26,251,614...26,252,075
JBrowse link
G H3C11 H3 clustered histone 11 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H3C11 mRNA CTD PMID:19013360 NCBI chr 6:27,871,845...27,872,346
Ensembl chr 6:27,871,845...27,872,346
JBrowse link
G H4C13 H4 clustered histone 13 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H4C13 mRNA CTD PMID:19013360 NCBI chr 6:27,873,148...27,873,534
Ensembl chr 6:27,873,148...27,873,534
JBrowse link
G HAX1 HCLS1 associated protein X-1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of HAX1 mRNA CTD PMID:17622302 NCBI chr 1:154,272,629...154,275,875
Ensembl chr 1:154,272,355...154,275,875
JBrowse link
G HIC2 HIC ZBTB transcriptional repressor 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of HIC2 mRNA CTD PMID:12756304 NCBI chr22:21,417,371...21,451,463
Ensembl chr22:21,417,371...21,451,463
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [HIF1A protein binds to CREBBP protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased ubiquitination of and results in increased expression of HIF1A protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of HIF1A protein
CTD PMID:16579968 PMID:16973622 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of HLA-DPB1 mRNA CTD PMID:12756304 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,936...33,089,696
JBrowse link
G HLX H2.0 like homeobox decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of HLX mRNA CTD PMID:12756304 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059
JBrowse link
G HMOX2 heme oxygenase 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of HMOX2 mRNA CTD PMID:12888634 NCBI chr16:4,474,736...4,510,347
Ensembl chr16:4,474,690...4,510,347
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha decreases activity
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of HNF4A protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of HNF4A protein]
CTD PMID:19637192 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845
JBrowse link
G HNMT histamine N-methyltransferase increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of HNMT mRNA CTD PMID:12756304 NCBI chr 2:137,964,473...138,016,364
Ensembl chr 2:137,964,020...138,016,364
JBrowse link
G IFI27 interferon alpha inducible protein 27 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IFI27 mRNA CTD PMID:12756304 NCBI chr14:94,105,894...94,116,690
Ensembl chr14:94,104,836...94,116,695
JBrowse link
G IFI6 interferon alpha inducible protein 6 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IFI6 mRNA CTD PMID:12756304 NCBI chr 1:27,666,064...27,672,192
Ensembl chr 1:27,666,064...27,672,212
JBrowse link
G IFNG interferon gamma multiple interactions EXP [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased activity of CASP3 protein; [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein; [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased secretion of IFNG protein]; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein]; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein] CTD PMID:16844947 PMID:17150331 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IFNGR1 interferon gamma receptor 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IFNGR1 mRNA CTD PMID:19013360 NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449
JBrowse link
G IFNGR2 interferon gamma receptor 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IFNGR2 mRNA CTD PMID:12756304 NCBI chr21:33,402,882...33,437,516
Ensembl chr21:33,403,413...33,479,348
JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:14644152 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF1R insulin like growth factor 1 receptor multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:14644152 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased phosphorylation of IKBKB protein] CTD PMID:16818790 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460
JBrowse link
G IL10 interleukin 10 multiple interactions
decreases expression
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in decreased secretion of IL10 protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IL10 mRNA
CTD PMID:17150331 PMID:19013360 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL10RA interleukin 10 receptor subunit alpha increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL10RA mRNA CTD PMID:19013360 NCBI chr11:117,986,394...118,003,037
Ensembl chr11:117,986,370...118,003,037
JBrowse link
G IL10RB interleukin 10 receptor subunit beta increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL10RB mRNA CTD PMID:19013360 NCBI chr21:33,266,367...33,310,182
Ensembl chr21:33,266,367...33,311,420
JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL13RA1 mRNA CTD PMID:19013360 NCBI chr  X:118,727,606...118,805,228
Ensembl chr  X:118,727,133...118,794,535
JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions
EXP
ISO
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL1B mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased secretion of IL1B protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]]
CTD PMID:17622302 PMID:19130485 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL2 interleukin 2 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased expression of FOS mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [IL2 protein results in increased phosphorylation of STAT5A protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [IL2 protein results in increased phosphorylation of STAT5B protein] CTD PMID:20201035 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL4 interleukin 4 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IL4 mRNA CTD PMID:19013360 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL4R interleukin 4 receptor decreases expression
increases expression
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IL4R mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL4R mRNA
CTD PMID:12756304 PMID:19013360 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IL6 interleukin 6 increases secretion
multiple interactions
EXP
ISO
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased secretion of IL6 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of IL6 mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of IL6 protein]
CTD PMID:16818790 PMID:18615482 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL6R interleukin 6 receptor increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL6R mRNA CTD PMID:19013360 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
JBrowse link
G INTS6 integrator complex subunit 6 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of INTS6 mRNA CTD PMID:12756304 NCBI chr13:51,334,405...51,453,036
Ensembl chr13:51,354,077...51,454,264
JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IQGAP2 mRNA CTD PMID:19013360 NCBI chr 5:76,403,285...76,708,132
Ensembl chr 5:76,403,285...76,708,132
JBrowse link
G IRF1 interferon regulatory factor 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IRF1 mRNA CTD PMID:12756304 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
JBrowse link
G ISG15 ISG15 ubiquitin like modifier increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of ISG15 mRNA CTD PMID:19013360 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540
JBrowse link
G ITGAM integrin subunit alpha M multiple interactions EXP [Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]; parthenolide promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]]; pyrithione promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]] CTD PMID:20089671 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G ITSN2 intersectin 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ITSN2 mRNA CTD PMID:12756304 NCBI chr 2:24,202,864...24,361,368
Ensembl chr 2:24,202,864...24,360,536
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased activity of JUN protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc Sulfate results in increased activity of JUN protein] CTD PMID:16606632 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KAT6A lysine acetyltransferase 6A decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of KAT6A mRNA CTD PMID:12756304 NCBI chr 8:41,929,479...42,051,987
Ensembl chr 8:41,929,479...42,051,994
JBrowse link
G KAZN kazrin, periplakin interacting protein decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of KAZN mRNA CTD PMID:12756304 NCBI chr 1:13,892,824...15,118,043
Ensembl chr 1:13,892,792...15,118,043
JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [dexamethasone 21-methanesulfonate binds to KEAP1 protein] CTD PMID:15865434 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KIF23 kinesin family member 23 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of KIF23 mRNA CTD PMID:12888634 NCBI chr15:69,414,349...69,448,427
Ensembl chr15:69,414,246...69,448,427
JBrowse link
G KRT8 keratin 8 increases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of KRT8 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of KRT8 mRNA]
CTD PMID:18778698 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 decreases expression
multiple interactions
EXP
ISO
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of LAMP2 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Ethambutol results in increased expression of LAMP2 protein]
CTD PMID:12888634 PMID:19063910 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365
JBrowse link
G LATS1 large tumor suppressor kinase 1 multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc binds to LATS1 protein] CTD PMID:35027733 NCBI chr 6:149,658,153...149,718,101
Ensembl chr 6:149,658,153...149,718,105
JBrowse link
G LATS2 large tumor suppressor kinase 2 decreases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of LATS2 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc binds to LATS2 protein]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of LATS2 mRNA]
CTD PMID:18778698 PMID:35027733 NCBI chr13:20,973,036...21,061,586
Ensembl chr13:20,973,036...21,061,586
JBrowse link
G LIG3 DNA ligase 3 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of LIG3 mRNA CTD PMID:33645215 NCBI chr17:34,980,512...35,010,872
Ensembl chr17:34,980,512...35,009,743
JBrowse link
G LILRA5 leukocyte immunoglobulin like receptor A5 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of LILRA5 mRNA CTD PMID:19013360 NCBI chr19:54,307,070...54,313,166
Ensembl chr19:54,307,070...54,313,166
JBrowse link
G LTA lymphotoxin alpha increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of LTA mRNA CTD PMID:12888634 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324
JBrowse link
G MAD2L1BP MAD2L1 binding protein decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MAD2L1BP mRNA CTD PMID:12756304 NCBI chr 6:43,629,540...43,640,941
Ensembl chr 6:43,629,540...43,640,941
JBrowse link
G MAP2K5 mitogen-activated protein kinase kinase 5 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MAP2K5 mRNA CTD PMID:12888634 NCBI chr15:67,542,703...67,807,114
Ensembl chr15:67,542,703...67,807,117
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:11331359 PMID:20201035 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:20201035 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPKBP1 mitogen-activated protein kinase binding protein 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MAPKBP1 mRNA CTD PMID:12756304 NCBI chr15:41,774,484...41,827,855
Ensembl chr15:41,774,434...41,827,855
JBrowse link
G MBNL2 muscleblind like splicing regulator 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MBNL2 mRNA CTD PMID:12756304 NCBI chr13:97,141,834...97,394,120
Ensembl chr13:97,221,434...97,394,120
JBrowse link
G MDM2 MDM2 proto-oncogene increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MDM2 mRNA CTD PMID:33645215 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
JBrowse link
G MMP10 matrix metallopeptidase 10 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MMP10 mRNA CTD PMID:12888634 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628
JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glutathione binds to MMP9 protein] CTD PMID:17015178 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MRPL12 mitochondrial ribosomal protein L12 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MRPL12 mRNA CTD PMID:19013360 NCBI chr17:81,703,367...81,707,517
Ensembl chr17:81,703,367...81,707,517
JBrowse link
G MT1A metallothionein 1A multiple interactions EXP
ISO
[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc co-treated with ochratoxin A] results in increased expression of MT1A mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of MT1A mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MT1A mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of MT1A mRNA]
CTD PMID:17018880 PMID:19720134 PMID:23056475 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
JBrowse link
G MT1B metallothionein 1B multiple interactions EXP [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc co-treated with ochratoxin A] results in increased expression of MT1B mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of MT1B mRNA CTD PMID:19720134 NCBI chr16:56,651,886...56,653,204
Ensembl chr16:56,651,886...56,653,204
JBrowse link
G MT1E metallothionein 1E multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MT1E mRNA] CTD PMID:17018880 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112
JBrowse link
G MT1G metallothionein 1G decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MT1G mRNA CTD PMID:19013360 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
JBrowse link
G MT1H metallothionein 1H decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MT1H mRNA CTD PMID:19013360 NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129
JBrowse link
G MT1L metallothionein 1L (pseudogene) decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MT1L mRNA CTD PMID:17622302 NCBI chr16:56,617,461...56,618,818
Ensembl chr16:56,617,563...56,618,680
JBrowse link
G MT1X metallothionein 1X multiple interactions
decreases expression
EXP
ISO
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MT1X mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in increased expression of MT1 mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MT1X mRNA
CTD PMID:14617770 PMID:17018880 PMID:19013360 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MT2A metallothionein 2A multiple interactions ISO
EXP
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in increased expression of MT2 mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of MT2A mRNA]
[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc co-treated with ochratoxin A] results in increased expression of MT2A mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of MT2A mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nickel results in increased expression of MT2A mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MT2A mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased expression of MT2A mRNA]
CTD PMID:14617770 PMID:17018880 PMID:19097988 PMID:19720134 PMID:23056475 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MTF1 metal regulatory transcription factor 1 multiple interactions
increases expression
EXP
ISO
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MTF1 mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [MTF1 protein binds to SLC39A10 promoter]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MTF1 mRNA
CTD PMID:12756304 PMID:12888634 PMID:17018880 PMID:21738690 NCBI chr 1:37,809,574...37,859,592
Ensembl chr 1:37,809,574...37,859,592
JBrowse link
G MTTP microsomal triglyceride transfer protein decreases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MTTP protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MTTP protein]
CTD PMID:19637192 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
JBrowse link
G MTX1 metaxin 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MTX1 mRNA CTD PMID:33645215 NCBI chr 1:155,208,695...155,213,839
Ensembl chr 1:155,208,695...155,213,824
JBrowse link
G MX2 MX dynamin like GTPase 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MX2 mRNA CTD PMID:19013360 NCBI chr21:41,362,027...41,409,393
Ensembl chr21:41,361,999...41,409,393
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MYC mRNA CTD PMID:19013360 PMID:33645215 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MYD88 mRNA CTD PMID:17622302 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
JBrowse link
G NAB2 NGFI-A binding protein 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NAB2 mRNA CTD PMID:12756304 NCBI chr12:57,089,114...57,095,476
Ensembl chr12:57,089,043...57,095,476
JBrowse link
G NCBP2 nuclear cap binding protein subunit 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of NCBP2 mRNA CTD PMID:12756304 NCBI chr 3:196,935,406...196,942,528
Ensembl chr 3:196,935,402...196,942,594
JBrowse link
G NCLN nicalin decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NCLN mRNA CTD PMID:12756304 NCBI chr19:3,185,930...3,209,575
Ensembl chr19:3,185,563...3,209,575
JBrowse link
G NFIC nuclear factor I C multiple interactions
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [NFIC protein binds to DSPP promoter]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of NFIC protein
CTD PMID:22228435 NCBI chr19:3,359,630...3,469,217
Ensembl chr19:3,314,403...3,469,217
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions
affects localization
EXP Copper inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the localization of NFKB1 protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the localization of NFKB1 protein] CTD PMID:18615482 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions
increases degradation
decreases expression
EXP Copper inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased degradation of NFKBIA protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased degradation of NFKBIA protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NFKBIA mRNA
CTD PMID:12756304 PMID:18615482 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NKX3-2 NK3 homeobox 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NKX3-2 mRNA CTD PMID:12756304 NCBI chr 4:13,540,830...13,547,744
Ensembl chr 4:13,540,830...13,544,508
JBrowse link
G NLGN1 neuroligin 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of NLGN1 mRNA CTD PMID:12756304 NCBI chr 3:173,395,952...174,294,372
Ensembl chr 3:173,396,284...174,294,372
JBrowse link
G NLRX1 NLR family member X1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NLRX1 mRNA CTD PMID:12756304 NCBI chr11:119,168,334...119,184,016
Ensembl chr11:119,166,568...119,184,016
JBrowse link
G NSMCE4A NSE4 homolog A, SMC5-SMC6 complex component decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NSMCE4A mRNA CTD PMID:12756304 NCBI chr10:121,957,091...121,975,217
Ensembl chr10:121,957,091...121,975,217
JBrowse link
G NUP50 nucleoporin 50 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of NUP50 mRNA CTD PMID:12756304 NCBI chr22:45,163,925...45,188,017
Ensembl chr22:45,163,925...45,188,017
JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of OGT mRNA CTD PMID:12756304 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892
JBrowse link
G OPRM1 opioid receptor mu 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FK 409 promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FK 409 promotes the reaction [OPRM1 protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to RAF1 protein]] CTD PMID:18652891 PMID:21235400 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
decreases activity
ISO
EXP
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of PARP1 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc binds to PARP1 protein]
CTD PMID:15966574 PMID:22253048 PMID:24275069 PMID:33645215 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PCNA proliferating cell nuclear antigen decreases ubiquitination EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased ubiquitination of PCNA protein CTD PMID:36087615 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of PIK3C3 mRNA CTD PMID:12756304 NCBI chr18:41,955,234...42,087,830
Ensembl chr18:41,955,234...42,087,830
JBrowse link
G PLSCR1 phospholipid scramblase 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PLSCR1 mRNA CTD PMID:12756304 NCBI chr 3:146,515,180...146,544,607
Ensembl chr 3:146,515,180...146,544,856
JBrowse link
G POLB DNA polymerase beta increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of POLB mRNA CTD PMID:33645215 NCBI chr 8:42,338,494...42,371,808
Ensembl chr 8:42,338,454...42,371,808
JBrowse link
G POLR2A RNA polymerase II subunit A decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of POLR2A mRNA CTD PMID:12756304 NCBI chr17:7,484,366...7,514,616
Ensembl chr17:7,484,366...7,514,616
JBrowse link
G POLR2D RNA polymerase II subunit D decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of POLR2D mRNA CTD PMID:12756304 NCBI chr 2:127,843,553...127,858,155
Ensembl chr 2:127,843,553...127,858,155
JBrowse link
G PON2 paraoxonase 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of PON2 mRNA CTD PMID:12888634 NCBI chr 7:95,404,862...95,435,028
Ensembl chr 7:95,404,862...95,435,329
JBrowse link
G POU4F2 POU class 4 homeobox 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of POU4F2 mRNA CTD PMID:12756304 NCBI chr 4:146,638,893...146,642,474
Ensembl chr 4:146,638,893...146,642,474
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases activity
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of PPARA protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of PPARA protein]
CTD PMID:19637192 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPP2R2D protein phosphatase 2 regulatory subunit Bdelta decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of PPP2R2D mRNA CTD PMID:12756304 NCBI chr10:131,901,008...131,971,533
Ensembl chr10:131,901,008...131,959,834
JBrowse link
G PRKCB protein kinase C beta multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of PRKCB protein] CTD PMID:16818790 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PRKCG protein kinase C gamma multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FK 409 promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 PMID:21235400 NCBI chr19:53,881,094...53,907,652
Ensembl chr19:53,879,190...53,907,652
JBrowse link
G PSMB2 proteasome 20S subunit beta 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PSMB2 mRNA CTD PMID:12756304 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526
JBrowse link
G PTCRA pre T cell antigen receptor alpha increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PTCRA mRNA CTD PMID:19013360 NCBI chr 6:42,916,053...42,925,838
Ensembl chr 6:42,915,989...42,925,838
JBrowse link
G PTH1R parathyroid hormone 1 receptor multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of PTH1R mRNA CTD PMID:19913120 NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799
JBrowse link
G PTP4A1 protein tyrosine phosphatase 4A1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PTP4A1 mRNA CTD PMID:12756304 NCBI chr 6:63,516,440...63,583,588
Ensembl chr 6:63,521,746...63,583,588
JBrowse link
G PTPRN protein tyrosine phosphatase receptor type N increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PTPRN mRNA CTD PMID:17622302 PMID:19013360 NCBI chr 2:219,289,623...219,309,401
Ensembl chr 2:219,289,623...219,309,648
JBrowse link
G PUS1 pseudouridine synthase 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of PUS1 mRNA CTD PMID:12756304 NCBI chr12:131,929,276...131,945,896
Ensembl chr12:131,929,200...131,945,896
JBrowse link
G QRICH1 glutamine rich 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of QRICH1 mRNA CTD PMID:12756304 NCBI chr 3:49,029,707...49,094,373
Ensembl chr 3:49,029,707...49,094,363
JBrowse link
G RAD18 RAD18 E3 ubiquitin protein ligase decreases ubiquitination EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased ubiquitination of RAD18 protein CTD PMID:36087615 NCBI chr 3:8,877,075...8,963,472
Ensembl chr 3:8,775,402...8,963,773
JBrowse link
G RAD51 RAD51 recombinase increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RAD51 mRNA CTD PMID:12888634 NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340
JBrowse link
G RAD51C RAD51 paralog C increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RAD51C mRNA CTD PMID:12756304 NCBI chr17:58,692,573...58,735,611
Ensembl chr17:58,692,573...58,735,611
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FK 409 promotes the reaction [OPRM1 protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to RAF1 protein]] CTD PMID:21235400 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201
JBrowse link
G RB1 RB transcriptional corepressor 1 increases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RB1 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RB1 mRNA]
CTD PMID:18778698 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in decreased activity of RELA protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc Sulfate results in decreased activity of RELA protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]]
CTD PMID:16606632 PMID:16818790 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G REPIN1 replication initiator 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of REPIN1 mRNA CTD PMID:12756304 NCBI chr 7:150,368,096...150,374,039
Ensembl chr 7:150,368,189...150,374,044
JBrowse link
G RGP1 RGP1 homolog, RAB6A GEF complex partner 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of RGP1 mRNA CTD PMID:12756304 NCBI chr 9:35,749,287...35,790,428
Ensembl chr 9:35,749,287...35,758,585
JBrowse link
G RIMS2 regulating synaptic membrane exocytosis 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RIMS2 mRNA CTD PMID:12756304 NCBI chr 8:103,500,610...104,256,094
Ensembl chr 8:103,500,610...104,254,430
JBrowse link
G RNF187 ring finger protein 187 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of RNF187 mRNA CTD PMID:12756304 NCBI chr 1:228,487,382...228,496,188
Ensembl chr 1:228,487,382...228,499,899
JBrowse link
G ROR1 receptor tyrosine kinase like orphan receptor 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of ROR1 mRNA CTD PMID:12756304 NCBI chr 1:63,774,017...64,181,498
Ensembl chr 1:63,774,017...64,181,498
JBrowse link
G RPL10 ribosomal protein L10 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of RPL10 mRNA CTD PMID:19013360 NCBI chr  X:154,398,065...154,402,339
Ensembl chr  X:154,389,955...154,409,168
JBrowse link
G RPRM reprimo, TP53 dependent G2 arrest mediator homolog increases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RPRM mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RPRM mRNA]
CTD PMID:18778698 NCBI chr 2:153,477,338...153,478,762
Ensembl chr 2:153,477,338...153,478,762
JBrowse link
G RPS2P45 ribosomal protein S2 pseudogene 45 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of RPS2P45 mRNA CTD PMID:19013360 NCBI chr16:69,033,630...69,034,561
Ensembl chr16:69,033,675...69,034,521
JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RPS6KA2 mRNA CTD PMID:19013360 NCBI chr 6:166,409,364...166,862,773
Ensembl chr 6:166,409,364...166,906,451
JBrowse link
G RRH retinal pigment epithelium-derived rhodopsin homolog increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RRH mRNA CTD PMID:19013360 NCBI chr 4:109,827,972...109,844,942
Ensembl chr 4:109,827,972...109,849,123
JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RRM2B mRNA CTD PMID:33645215 NCBI chr 8:102,204,501...102,238,961
Ensembl chr 8:102,204,502...102,238,961
JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of RUNX2 protein; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 protein CTD PMID:19913120 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G S100A12 S100 calcium binding protein A12 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A12 mRNA CTD PMID:19013360 NCBI chr 1:153,373,711...153,375,621
Ensembl chr 1:153,373,711...153,375,621
JBrowse link
G S100A4 S100 calcium binding protein A4 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A4 mRNA CTD PMID:19013360 NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136
JBrowse link
G S100A6 S100 calcium binding protein A6 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A6 mRNA CTD PMID:19013360 NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244
JBrowse link
G S100A8 S100 calcium binding protein A8 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A8 mRNA CTD PMID:19013360 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
JBrowse link
G S100A9 S100 calcium binding protein A9 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A9 mRNA CTD PMID:19013360 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
JBrowse link
G S100P S100 calcium binding protein P decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of S100P mRNA CTD PMID:19013360 NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170
JBrowse link
G SCG3 secretogranin III increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SCG3 mRNA CTD PMID:19013360 NCBI chr15:51,681,503...51,721,026
Ensembl chr15:51,681,492...51,721,026
JBrowse link
G SEC16A SEC16 homolog A, endoplasmic reticulum export factor decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SEC16A mRNA CTD PMID:12756304 NCBI chr 9:136,440,105...136,484,740
Ensembl chr 9:136,440,096...136,483,759
JBrowse link
G SESN1 sestrin 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SESN1 mRNA CTD PMID:12756304 NCBI chr 6:108,984,309...109,094,846
Ensembl chr 6:108,984,309...109,094,846
JBrowse link
G SFN stratifin increases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SFN mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SFN mRNA]
CTD PMID:18778698 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456
JBrowse link
G SIDT2 SID1 transmembrane family member 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SIDT2 mRNA CTD PMID:12756304 NCBI chr11:117,178,743...117,197,442
Ensembl chr11:117,178,736...117,197,445
JBrowse link
G SLC11A2 solute carrier family 11 member 2 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC11A2 mRNA CTD PMID:19083439 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566
JBrowse link
G SLC25A39 solute carrier family 25 member 39 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC25A39 mRNA CTD PMID:19013360 NCBI chr17:44,319,628...44,324,823
Ensembl chr17:44,319,625...44,324,870
JBrowse link
G SLC30A1 solute carrier family 30 member 1 multiple interactions
decreases expression
EXP
ISO
[Zinc co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of SLC30A1 mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of SLC30A1 mRNA]; ochratoxin A promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC30A1 mRNA]; Zinc inhibits the reaction [ochratoxin A promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC30A1 mRNA]]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of SLC30A1 mRNA]
CTD PMID:12756304 PMID:17018880 PMID:19720134 PMID:23056475 NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
JBrowse link
G SLC30A5 solute carrier family 30 member 5 multiple interactions
increases expression
decreases expression
EXP [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with ochratoxin A] results in decreased expression of SLC30A5 mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in decreased expression of SLC30A5 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC30A5 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC30A5 mRNA
CTD PMID:15276077 PMID:17234632 PMID:19720134 NCBI chr 5:69,094,014...69,131,069
Ensembl chr 5:69,093,991...69,131,069
JBrowse link
G SLC30A6 solute carrier family 30 member 6 multiple interactions EXP [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with ochratoxin A] results in decreased expression of SLC30A6 mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of SLC30A6 mRNA CTD PMID:19720134 NCBI chr 2:32,165,864...32,224,379
Ensembl chr 2:32,165,841...32,224,379
JBrowse link
G SLC30A7 solute carrier family 30 member 7 multiple interactions
increases expression
EXP [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with ochratoxin A co-treated with Zinc] results in decreased expression of SLC30A7 mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of SLC30A7 mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [ochratoxin A results in decreased expression of SLC30A7 mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC30A7 mRNA
CTD PMID:15276077 PMID:17068819 PMID:19720134 NCBI chr 1:100,896,090...100,996,078
Ensembl chr 1:100,896,076...100,996,260
JBrowse link
G SLC30A8 solute carrier family 30 member 8 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Glucose results in decreased expression of SLC30A8 mRNA] CTD PMID:23056475 NCBI chr 8:116,950,217...117,176,714
Ensembl chr 8:116,950,273...117,176,714
JBrowse link
G SLC39A1 solute carrier family 39 member 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A1 mRNA CTD PMID:17622302 NCBI chr 1:153,959,110...153,968,184
Ensembl chr 1:153,959,099...153,968,184
JBrowse link
G SLC39A10 solute carrier family 39 member 10 multiple interactions
increases expression
EXP
ISO
[ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in decreased expression of SLC39A10 mRNA; [ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SLC39A10 mRNA; [Zinc co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SLC39A10 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 protein
Dactinomycin inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [MTF1 protein binds to SLC39A10 promoter]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 mRNA]
CTD PMID:19720134 PMID:21738690 NCBI chr 2:195,613,029...195,737,700
Ensembl chr 2:195,575,977...195,737,702
JBrowse link
G SLC39A13 solute carrier family 39 member 13 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC39A13 mRNA CTD PMID:22228435 NCBI chr11:47,407,276...47,416,500
Ensembl chr11:47,407,132...47,416,496
JBrowse link
G SLC39A14 solute carrier family 39 member 14 multiple interactions EXP [ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SLC39A14 mRNA CTD PMID:19720134 NCBI chr 8:22,367,278...22,434,129
Ensembl chr 8:22,367,278...22,434,129
JBrowse link
G SLC39A2 solute carrier family 39 member 2 decreases expression
increases expression
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC39A2 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A2 mRNA
CTD PMID:12756304 PMID:18385089 NCBI chr14:20,999,293...21,001,871
Ensembl chr14:20,999,255...21,001,871
JBrowse link
G SLC39A4 solute carrier family 39 member 4 increases expression EXP
ISO
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A4 mRNA CTD PMID:18020946 PMID:19083439 NCBI chr 8:144,412,414...144,416,844
Ensembl chr 8:144,409,742...144,416,844
JBrowse link
G SLC39A5 solute carrier family 39 member 5 decreases response to substance ISO SLC39A5 protein results in decreased susceptibility to N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine CTD PMID:15322118 NCBI chr12:56,230,051...56,237,846
Ensembl chr12:56,230,049...56,237,846
JBrowse link
G SLC39A6 solute carrier family 39 member 6 multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form results in decreased susceptibility to trichostatin A]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form results in decreased susceptibility to trichostatin A]] CTD PMID:19887557 NCBI chr18:36,108,531...36,129,340
Ensembl chr18:36,108,531...36,129,385
JBrowse link
G SLC7A1 solute carrier family 7 member 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC7A1 mRNA CTD PMID:12756304 NCBI chr13:29,509,414...29,595,688
Ensembl chr13:29,509,414...29,595,688
JBrowse link
G SLC9A6 solute carrier family 9 member A6 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC9A6 mRNA CTD PMID:12756304 NCBI chr  X:135,973,837...136,047,269
Ensembl chr  X:135,973,841...136,047,269
JBrowse link
G SLCO1C1 solute carrier organic anion transporter family member 1C1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLCO1C1 mRNA CTD PMID:17622302 PMID:19013360 NCBI chr12:20,695,332...20,753,386
Ensembl chr12:20,695,332...20,753,386
JBrowse link
G SMIM7 small integral membrane protein 7 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SMIM7 mRNA CTD PMID:12756304 NCBI chr19:16,630,751...16,660,144
Ensembl chr19:16,630,751...16,660,442
JBrowse link
G SNAP25 synaptosome associated protein 25 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Botulinum Toxins, Type A results in increased cleavage of SNAP25 protein] CTD PMID:11181932 NCBI chr20:10,218,830...10,307,418
Ensembl chr20:10,172,395...10,308,258
JBrowse link
G SOD1 superoxide dismutase 1 increases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SOD1 mRNA
[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine binds to Zinc] inhibits the reaction [SOD1 protein binds to Oligodeoxyribonucleotides]
CTD PMID:12888634 PMID:31162603 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SPEN spen family transcriptional repressor decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SPEN mRNA CTD PMID:12756304 NCBI chr 1:15,847,707...15,940,456
Ensembl chr 1:15,836,095...15,940,456
JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of SPP1 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SPP1 mRNA CTD PMID:19913120 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased phosphorylation of SRC protein] CTD PMID:12972402 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SRSF5 mRNA CTD PMID:12756304 NCBI chr14:69,767,142...69,772,005
Ensembl chr14:69,726,900...69,772,005
JBrowse link
G STAT1 signal transducer and activator of transcription 1 increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of STAT1 mRNA CTD PMID:19013360 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
G STAT3 signal transducer and activator of transcription 3 decreases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STAT3 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STAT3 mRNA]
CTD PMID:18778698 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G STAT5A signal transducer and activator of transcription 5A multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [IL2 protein results in increased phosphorylation of STAT5A protein] CTD PMID:20201035 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943
JBrowse link
G STAT5B signal transducer and activator of transcription 5B multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [IL2 protein results in increased phosphorylation of STAT5B protein] CTD PMID:20201035 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633
JBrowse link
G STEAP4 STEAP4 metalloreductase increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of STEAP4 mRNA CTD PMID:12756304 NCBI chr 7:88,270,892...88,306,894
Ensembl chr 7:88,270,892...88,306,894
JBrowse link
G STK10 serine/threonine kinase 10 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STK10 mRNA CTD PMID:12756304 NCBI chr 5:172,042,079...172,188,224
Ensembl chr 5:172,042,079...172,188,224
JBrowse link
G SYNRG synergin gamma decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SYNRG mRNA CTD PMID:12756304 NCBI chr17:37,514,807...37,609,418
Ensembl chr17:37,514,807...37,609,472
JBrowse link
G TBC1D8 TBC1 domain family member 8 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TBC1D8 mRNA CTD PMID:12756304 NCBI chr 2:101,007,228...101,151,382
Ensembl chr 2:101,007,228...101,252,866
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TGFBR2 mRNA CTD PMID:12756304 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249
JBrowse link
G THOP1 thimet oligopeptidase 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of THOP1 mRNA CTD PMID:19013360 NCBI chr19:2,785,503...2,815,807
Ensembl chr19:2,785,503...2,815,807
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 increases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TIMP3 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TIMP3 mRNA]
CTD PMID:18778698 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041
JBrowse link
G TLE1 TLE family member 1, transcriptional corepressor decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TLE1 mRNA CTD PMID:12756304 NCBI chr 9:81,583,683...81,689,547
Ensembl chr 9:81,583,683...81,689,547
JBrowse link
G TMEM184C transmembrane protein 184C increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TMEM184C mRNA CTD PMID:12756304 NCBI chr 4:147,617,397...147,636,721
Ensembl chr 4:147,617,386...147,672,044
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO
[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased activity of CASP3 protein; [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein; [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [[Calcitriol co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of TNF protein]; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein]; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of TNF mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of TNF protein]
CTD PMID:16818790 PMID:16844947 PMID:20089671 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP8 TNF alpha induced protein 8 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TNFAIP8 mRNA CTD PMID:12756304 NCBI chr 5:119,268,759...119,399,688
Ensembl chr 5:119,268,692...119,399,688
JBrowse link
G TNS3 tensin 3 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TNS3 mRNA CTD PMID:12756304 NCBI chr 7:47,275,154...47,582,586
Ensembl chr 7:47,275,154...47,582,558
JBrowse link
G TP53 tumor protein p53 affects localization
multiple interactions
increases expression
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the localization of TP53 protein
[Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of LATS2 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STAT3 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of KRT8 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RB1 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RPRM mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SFN mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TIMP3 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP73 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of YWHAZ mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP53 protein
CTD PMID:12888634 PMID:18778698 PMID:18951928 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TP73 tumor protein p73 increases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP73 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP73 mRNA]
CTD PMID:18778698 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
JBrowse link
G TRAK1 trafficking kinesin protein 1 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TRAK1 mRNA CTD PMID:12756304 NCBI chr 3:42,013,093...42,225,890
Ensembl chr 3:42,013,624...42,225,890
JBrowse link
G TST thiosulfate sulfurtransferase decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TST mRNA CTD PMID:12756304 NCBI chr22:37,010,859...37,020,183
Ensembl chr22:37,010,859...37,020,183
JBrowse link
G TXNIP thioredoxin interacting protein increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TXNIP mRNA CTD PMID:19013360 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
JBrowse link
G TYMS thymidylate synthetase increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TYMS mRNA CTD PMID:12888634 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of UGCG mRNA CTD PMID:12756304 NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369
JBrowse link
G UNG uracil DNA glycosylase increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of UNG mRNA CTD PMID:12888634 NCBI chr12:109,097,597...109,110,992
Ensembl chr12:109,097,597...109,126,725
JBrowse link
G USP24 ubiquitin specific peptidase 24 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of USP24 mRNA CTD PMID:12756304 NCBI chr 1:55,066,359...55,215,364
Ensembl chr 1:55,066,359...55,215,378
JBrowse link
G USP5 ubiquitin specific peptidase 5 multiple interactions ISO 3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of USP5 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of USP5 protein CTD PMID:29129814 NCBI chr12:6,852,150...6,866,632
Ensembl chr12:6,852,148...6,866,632
JBrowse link
G UVRAG UV radiation resistance associated increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of UVRAG mRNA CTD PMID:12888634 NCBI chr11:75,815,210...76,144,232
Ensembl chr11:75,815,210...76,144,232
JBrowse link
G VDAC1 voltage dependent anion channel 1 decreases expression
increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC1 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of VDAC1 protein
Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC1 mRNA]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of VDAC1 protein]
CTD PMID:21605504 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
JBrowse link
G VDAC2 voltage dependent anion channel 2 decreases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 protein
Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 mRNA]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 protein]
CTD PMID:21605504 NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448
JBrowse link
G VEGFA vascular endothelial growth factor A decreases expression
increases secretion
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VEGFA mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased secretion of VEGFA protein
CTD PMID:18615482 PMID:20957409 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VPS33B VPS33B late endosome and lysosome associated decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VPS33B mRNA CTD PMID:12756304 NCBI chr15:90,998,416...91,022,621
Ensembl chr15:90,998,673...91,022,603
JBrowse link
G VSIR V-set immunoregulatory receptor increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of VSIR mRNA CTD PMID:19013360 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
JBrowse link
G WIPF2 WAS/WASL interacting protein family member 2 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of WIPF2 mRNA CTD PMID:12756304 NCBI chr17:40,219,304...40,284,136
Ensembl chr17:40,219,304...40,284,136
JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor increases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of XPC mRNA CTD PMID:33645215 NCBI chr 3:14,145,147...14,178,601
Ensembl chr 3:14,145,145...14,178,621
JBrowse link
G YJU2B YJU2 splicing factor homolog B decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of YJU2B mRNA CTD PMID:12756304 NCBI chr19:13,731,752...13,763,289
Ensembl chr19:13,731,760...13,763,296
JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta increases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of YWHAZ mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of YWHAZ mRNA]
CTD PMID:18778698 NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388
JBrowse link
G ZCCHC8 zinc finger CCHC-type containing 8 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZCCHC8 mRNA CTD PMID:12756304 NCBI chr12:122,471,600...122,500,932
Ensembl chr12:122,471,600...122,500,932
JBrowse link
G ZFP36 ZFP36 ring finger protein decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZFP36 mRNA CTD PMID:12756304 NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407
JBrowse link
G ZFP64 ZFP64 zinc finger protein decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZFP64 mRNA CTD PMID:12756304 NCBI chr20:52,084,011...52,191,779
Ensembl chr20:52,051,663...52,204,308
JBrowse link
G ZFPM1 zinc finger protein, FOG family member 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [GATA1 protein binds to ZFPM1 protein] CTD PMID:33149232 NCBI chr16:88,451,769...88,537,031
Ensembl chr16:88,453,280...88,537,031
JBrowse link
G ZFTA zinc finger translocation associated decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZFTA mRNA CTD PMID:12756304 NCBI chr11:63,759,892...63,768,775
Ensembl chr11:63,759,892...63,768,775
JBrowse link
G ZNF512B zinc finger protein 512B decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZNF512B mRNA CTD PMID:12756304 NCBI chr20:63,956,704...63,969,930
Ensembl chr20:63,956,704...63,969,930
JBrowse link
G ZNF764 zinc finger protein 764 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZNF764 mRNA CTD PMID:12756304 NCBI chr16:30,553,764...30,558,374
Ensembl chr16:30,553,764...30,558,374
JBrowse link
G ZNF816 zinc finger protein 816 decreases expression EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZNF816 mRNA CTD PMID:12756304 NCBI chr19:52,949,385...52,962,881
Ensembl chr19:52,949,379...52,962,911
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26504
    role 26326
      chemical role 24361
        ligand 6956
          chelator 6938
            N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine 302
Path 2
Term Annotations click to browse term
  CHEBI ontology 26504
    subatomic particle 26480
      composite particle 26480
        hadron 26480
          baryon 26480
            nucleon 26480
              atomic nucleus 26480
                atom 26480
                  main group element atom 26217
                    main group molecular entity 26217
                      s-block molecular entity 25454
                        hydrogen molecular entity 24861
                          hydrides 23080
                            inorganic hydride 20556
                              pnictogen hydride 20498
                                nitrogen hydride 20283
                                  azane 20008
                                    ammonia 20007
                                      organic amino compound 20007
                                        polyamine 9574
                                          diamine 9511
                                            primary diamine 6237
                                              alkane-alpha,omega-diamine 4132
                                                ethylenediamine 4106
                                                  N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine 302
paths to the root