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Gene: FEZ1 (fasciculation and elongation protein zeta 1) Homo sapiens
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Symbol: FEZ1
Name: fasciculation and elongation protein zeta 1
Description: Predicted to have gamma-tubulin binding activity; protein N-terminus binding activity; and protein kinase C binding activity. Involved in negative regulation of autophagosome assembly. Localizes to Golgi apparatus. Biomarker of schizophrenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: fasciculation and elongation protein zeta 1 (zygin I); fasciculation and elongation protein zeta-1; protein kinase c-binding protein zeta1; UNC-76; zygin I; zygin-1
Orthologs:
Mus musculus (house mouse) : Fez1 (fasciculation and elongation protein zeta 1 (zygin I))  MGI  Alliance
Rattus norvegicus (Norway rat) : Fez1 (fasciculation and elongation protein zeta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fez1 (fasciculation and elongation protein zeta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FEZ1 (fasciculation and elongation protein zeta 1)
Canis lupus familiaris (dog) : FEZ1 (fasciculation and elongation protein zeta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fez1 (fasciculation and elongation protein zeta 1)
Sus scrofa (pig) : FEZ1 (fasciculation and elongation protein zeta 1)
Chlorocebus sabaeus (African green monkey) : FEZ1 (fasciculation and elongation protein zeta 1)
Heterocephalus glaber (naked mole-rat) : Fez1 (fasciculation and elongation protein zeta 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl11125,442,881 - 125,592,568 (-)EnsemblGRCh38hg38GRCh38
GRCh3811125,442,881 - 125,496,310 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711125,315,641 - 125,366,206 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,820,858 - 124,871,333 (-)NCBINCBI36hg18NCBI36
Build 3411124,863,305 - 124,871,333NCBI
Celera11122,475,971 - 122,526,454 (-)NCBI
Cytogenetic Map11q24.2NCBI
HuRef11121,257,207 - 121,307,713 (-)NCBIHuRef
CHM1_111125,201,870 - 125,252,371 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FEZ1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732377
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.