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Gene: MX2 (MX dynamin like GTPase 2) Homo sapiens
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Symbol: MX2
Name: MX dynamin like GTPase 2
Description: Exhibits GTP binding activity. Involved in several processes, including defense response to virus; regulation of nucleocytoplasmic transport; and response to interferon-alpha. Localizes to nuclear pore.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: interferon-induced GTP-binding protein Mx2; interferon-regulated resistance GTP-binding protein MXB; MX dynamin-like GTPase 2; MXB; myxovirus (influenza virus) resistance 2; myxovirus resistance protein 2; p78-related protein; second interferon-induced protein p78
Orthologs:
Pan paniscus (bonobo/pygmy chimpanzee) : MX2 (MX dynamin like GTPase 2)
Canis lupus familiaris (dog) : MX2 (MX dynamin like GTPase 2)
Chlorocebus sabaeus (African green monkey) : MX2 (MX dynamin like GTPase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2141,361,999 - 41,409,393 (+)EnsemblGRCh38hg38GRCh38
GRCh382141,361,944 - 41,409,393 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372142,733,918 - 42,780,870 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362141,655,820 - 41,702,739 (+)NCBINCBI36hg18NCBI36
Build 342141,655,819 - 41,702,739NCBI
Celera2127,932,197 - 27,979,096 (+)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2128,202,853 - 28,249,753 (+)NCBIHuRef
CHM1_12142,294,753 - 42,341,669 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MX2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351068
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.