Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NKX3-2 (NK3 homeobox 2) Homo sapiens
Symbol: NKX3-2
Name: NK3 homeobox 2
Description: Exhibits sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including digestive system development; negative regulation of chondrocyte differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bagpipe homeobox protein homolog 1; BAPX1; homeobox protein NK-3 homolog B; homeobox protein Nkx-3.2; MGC138171; NKX3.2; NKX3B; SMMD
Mus musculus (house mouse) : Nkx3-2 (NK3 homeobox 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nkx3-2 (NK3 homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkx3-2 (NK3 homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NKX3-2 (NK3 homeobox 2)
Canis lupus familiaris (dog) : NKX3-2 (NK3 homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkx3-2 (NK3 homeobox 2)
Sus scrofa (pig) : NKX3-2 (NK3 homeobox 2)
Chlorocebus sabaeus (African green monkey) : NKX3-2 (NK3 homeobox 2)
Heterocephalus glaber (naked mole-rat) : Nkx3-2 (NK3 homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl413,540,830 - 13,544,508 (-)EnsemblGRCh38hg38GRCh38
GRCh38413,540,830 - 13,544,508 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37413,542,454 - 13,546,114 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36413,151,552 - 13,155,212 (-)NCBINCBI36hg18NCBI36
Build 34413,218,722 - 13,222,307NCBI
Celera414,008,663 - 14,012,323 (-)NCBI
Cytogenetic Map4p15.33NCBI
HuRef412,880,106 - 12,883,766 (-)NCBIHuRef
CHM1_1413,541,051 - 13,544,711 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NKX3-2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353604
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.