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Gene: DSTN (destrin, actin depolymerizing factor) Homo sapiens
Symbol: DSTN
Name: destrin, actin depolymerizing factor
Description: Exhibits actin filament binding activity. Involved in actin filament depolymerization. Localizes to extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACTDP; actin-depolymerizing factor; ADF; bA462D18.2; bA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP)); destrin; destrin (actin depolymerizing factor); epididymis luminal protein 32; HEL32
Mus musculus (house mouse) : Dstn (destrin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dstn (destrin, actin depolymerizing factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dstn (destrin, actin depolymerizing factor)
Pan paniscus (bonobo/pygmy chimpanzee) : DSTN (destrin, actin depolymerizing factor)
Canis lupus familiaris (dog) : DSTN (destrin, actin depolymerizing factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dstn (destrin, actin depolymerizing factor)
Sus scrofa (pig) : DSTN (destrin, actin depolymerizing factor)
Chlorocebus sabaeus (African green monkey) : DSTN (destrin, actin depolymerizing factor)
Heterocephalus glaber (naked mole-rat) : Dstn (destrin, actin depolymerizing factor)
more info ...
Related Pseudogenes: DSTNP1   DSTNP2   DSTNP3   DSTNP5  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2017,570,075 - 17,609,919 (+)EnsemblGRCh38hg38GRCh38
GRCh382017,569,173 - 17,609,919 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372017,549,818 - 17,588,887 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362017,498,599 - 17,536,652 (+)NCBINCBI36hg18NCBI36
Build 342017,498,598 - 17,536,651NCBI
Celera2017,625,081 - 17,663,141 (+)NCBI
Cytogenetic Map20p12.1NCBI
HuRef2017,513,288 - 17,551,352 (+)NCBIHuRef
CHM1_12017,550,604 - 17,588,662 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DSTN
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312065
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.