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Gene: UNG (uracil DNA glycosylase) Homo sapiens
Symbol: UNG
Name: uracil DNA glycosylase
Description: Exhibits damaged DNA binding activity; ribosomal small subunit binding activity; and uracil DNA N-glycosylase activity. Involved in base-excision repair, AP site formation via deaminated base removal. Localizes to the nucleoplasm. Implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DGU; DKFZp781L1143; HIGM4; HIGM5; UDG; UNG1; UNG15; UNG2; uracil-DNA glycosylase; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; uracil-DNA glycosylase 2
Mus musculus (house mouse) : Ung (uracil DNA glycosylase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ung (uracil-DNA glycosylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ung (uracil DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : UNG (uracil DNA glycosylase)
Canis lupus familiaris (dog) : UNG (uracil DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ung (uracil DNA glycosylase)
Sus scrofa (pig) : UNG (uracil DNA glycosylase)
Chlorocebus sabaeus (African green monkey) : UNG (uracil DNA glycosylase)
Heterocephalus glaber (naked mole-rat) : Ung (uracil DNA glycosylase)
more info ...
Related Pseudogenes: UNGP1   UNGP2   UNGP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: Due to a common symbol (UNG2) for the specific nuclear isoform of the UNG gene (GeneID 7374) and as a previous symbol for the CCNO gene (GeneID 10309), incorrect attributions of uracil DNA glycosylase activity have been made for CCNO in the scientific literature and some databases. CCNO was correctly identified as a cyclin protein family member in PubMed ID: 8419333. [13 Feb 2013]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl12109,097,574 - 109,110,992 (+)Ensembl
GRCh3812109,097,597 - 109,110,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712109,535,399 - 109,548,798 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,019,798 - 108,033,181 (+)NCBINCBI36hg18NCBI36
Build 3412107,998,134 - 108,011,518NCBI
Celera12109,159,338 - 109,172,962 (+)NCBI
Cytogenetic Map12q24.11NCBI
HuRef12106,553,817 - 106,567,575 (+)NCBIHuRef
CHM1_112109,503,049 - 109,516,448 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on UNG
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316252
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.