The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein] 1,1-dimethyl-4-phenylpiperazinium iodide affects binding competes with [Epibatidine binds to Chrna2 protein]
Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein] 1,1-dimethyl-4-phenylpiperazinium iodide affects binding [Epibatidine binds to Chrna3 protein]
Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein] 1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrna4 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrna4 protein]
Dimethylphenylpiperazinium Iodide inhibits the reaction [Bungarotoxins binds to CHRNA7 protein] CHRNA7 protein mutant form results in increased susceptibility to Dimethylphenylpiperazinium Iodide Dimethylphenylpiperazinium Iodide results in increased activity of CHRNA7 protein
Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein] 1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrnb2 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrnb2 protein]
Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein]
Echothiophate Iodide results in decreased activity of BCHE protein Echothiophate Iodide inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]
3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein] which results in increased expression of Iodides; [[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]; fenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Glyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]
Iodides deficiency results in increased expression of DMGDH protein hexabromocyclododecane inhibits the reaction [Iodides deficiency results in increased expression of DMGDH protein]
Dexamethasone promotes the reaction [SLC5A5 protein results in increased uptake of Iodides]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]; potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]; thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides] Iodides deficiency affects the expression of SLC5A5 mRNA
[Iodides deficiency co-treated with perchlorate] results in increased expression of TSHB protein Iodides deficiency results in increased expression of TSHB protein
Potassium Iodide results in increased phosphorylation of AKT1 protein NOX4 protein affects the reaction [Potassium Iodide results in increased phosphorylation of AKT1 protein]; Selenium inhibits the reaction [Potassium Iodide results in increased phosphorylation of AKT1 protein]
Potassium Iodide results in increased expression of BECN1 mRNA; Potassium Iodide results in increased expression of BECN1 protein 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 mRNA]; 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 protein]
[Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of DDIT3 mRNA; Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased expression of DDIT3 protein] Potassium Iodide results in increased expression of DDIT3 mRNA
[Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of ERN1 mRNA; Potassium Iodide promotes the reaction [Sodium Fluoride results in increased expression of ERN1 protein]
[bisphenol A co-treated with diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of ESR1 protein; [Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein
[Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TPO promoter; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 protein]
Potassium Iodide results in decreased expression of GPX1 mRNA [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Potassium Iodide] results in increased expression of GPX1 mRNA; Selenium inhibits the reaction [Potassium Iodide results in decreased expression of GPX1 mRNA]
Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased expression of HSPA5 mRNA]; Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased expression of HSPA5 protein]
[Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to SLC5A5 enhancer; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TPO promoter; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of NKX2-1 mRNA]
Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 enhancer]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TG promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TPO promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 protein]
[Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of PCNA protein Potassium Iodide results in decreased expression of PCNA protein
Potassium Iodide inhibits the reaction [arsenic trioxide results in increased expression of PTGS2 mRNA]; Potassium Iodide inhibits the reaction [arsenic trioxide results in increased expression of PTGS2 protein]; Potassium Iodide inhibits the reaction [monomethylarsonous acid results in increased expression of PTGS2 mRNA] Potassium Iodide results in decreased expression of PTGS2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Potassium Iodide results in decreased expression of SLC5A5 mRNA]; 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Potassium Iodide results in decreased expression of SLC5A5 mRNA]; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to SLC5A5 enhancer; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 enhancer]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein]; Selenium inhibits the reaction [Potassium Iodide results in decreased expression of SLC5A5 mRNA]
3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA]; 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 protein] Potassium Iodide results in increased expression of SQSTM1 mRNA; Potassium Iodide results in increased expression of SQSTM1 protein
[Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TG promoter; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TG promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG protein]
[Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TPO promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TPO promoter; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TPO promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO protein]
[diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of TSHB protein; [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TPO promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to SLC5A5 enhancer; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TPO promoter; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 enhancer]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TG promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TPO promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of DUOX1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of DUOX2 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of NKX2-1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Potassium Iodide results in decreased expression of TXNRD1 mRNA]; Selenium inhibits the reaction [Potassium Iodide results in decreased expression of TXNRD1 mRNA]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; Ouabain inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; perchlorate inhibits the reaction [mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]]; perchlorate inhibits the reaction [SLC5A5 protein results in increased abundance of Sodium Iodide]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; perrhenate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; Sodium Iodide inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; Sodium Iodide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; sodium thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog] Sodium Iodide results in increased activity of SLC5A5 protein SLC5A5 protein results in decreased export of Sodium Iodide
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