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Gene: Dmgdh (dimethylglycine dehydrogenase) Rattus norvegicus
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Symbol: Dmgdh
Name: dimethylglycine dehydrogenase
Description: Exhibits dimethylglycine dehydrogenase activity; flavin adenine dinucleotide binding activity; and folic acid binding activity. Involved in tetrahydrofolate interconversion. Localizes to the mitochondrion. Orthologous to human DMGDH (dimethylglycine dehydrogenase); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; folate cycle metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dimethylglycine dehydrogenase precursor; dimethylglycine dehydrogenase, mitochondrial; Me2GlyDH
Orthologs:
Homo sapiens (human) : DMGDH (dimethylglycine dehydrogenase)  HGNC  Alliance
Mus musculus (house mouse) : Dmgdh (dimethylglycine dehydrogenase precursor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dmgdh (dimethylglycine dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : DMGDH (dimethylglycine dehydrogenase)
Canis lupus familiaris (dog) : DMGDH (dimethylglycine dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dmgdh (dimethylglycine dehydrogenase)
Sus scrofa (pig) : DMGDH (dimethylglycine dehydrogenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0223,289,376 - 23,370,360 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl223,289,374 - 23,370,477 (+)Ensembl
Rnor_5.0242,469,950 - 42,545,633 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4223,976,563 - 24,052,766 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1223,896,931 - 23,973,132 (+)NCBI
Celera220,986,895 - 21,062,849 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dmgdh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620453
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.