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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:potassium iodide
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Accession:CHEBI:8346 term browser browse the term
Definition:A metal iodide salt with a K(+) counterion. It is a scavenger of hydroxyl radicals.
Synonyms:related_synonym: Formula=IK;   Formula=K.I;   InChI=1S/HI.K/h1H;/q;+1/p-1;   InChIKey=NLKNQRATVPKPDG-UHFFFAOYSA-M;   KI;   Kaliumiodid;   SMILES=[K+].[I-]
 xref: CAS:7681-11-0;   KEGG:C08219;   KEGG:D01016
 xref_mesh: MESH:D011193
 xref: PMID:11004629;   PMID:15206581;   PMID:23475155;   PMID:23793210;   PMID:24044784;   PMID:24635765;   PPDB:1529;   Wikipedia:Potassium_Iodide

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potassium iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor decreases expression EXP Potassium Iodide results in decreased expression of AR mRNA CTD PMID:32593569 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Potassium Iodide results in increased expression of BAX protein CTD PMID:32593569 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Potassium Iodide results in decreased expression of BCL2 protein CTD PMID:32593569 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions		 ISO Potassium Iodide results in increased expression of BECN1 mRNA; Potassium Iodide results in increased expression of BECN1 protein
3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 mRNA]; 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 protein]		 CTD PMID:29923297 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression EXP Potassium Iodide results in increased expression of BID protein CTD PMID:32593569 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP Potassium Iodide results in decreased expression of BIRC5 protein CTD PMID:32593569 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Casp3 caspase 3 increases expression EXP Potassium Iodide results in increased expression of CASP3 protein CTD PMID:32593569 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp9 caspase 9 increases expression EXP Potassium Iodide results in increased expression of CASP9 protein CTD PMID:32593569 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Potassium Iodide results in decreased expression of CCND1 protein CTD PMID:32593569 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Cdh1 cadherin 1 decreases expression EXP Potassium Iodide results in decreased expression of CDH1 protein CTD PMID:32593569 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395 		JBrowse link
G Cdh2 cadherin 2 decreases expression EXP Potassium Iodide results in decreased expression of CDH2 protein CTD PMID:32593569 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression EXP Potassium Iodide results in decreased expression of CDK4 protein CTD PMID:32593569 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418 		JBrowse link
G Cldn1 claudin 1 decreases expression EXP Potassium Iodide results in decreased expression of CLDN1 mRNA CTD PMID:32593569 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416 		JBrowse link
G Cldn5 claudin 5 decreases expression EXP Potassium Iodide results in decreased expression of CLDN5 mRNA CTD PMID:32593569 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression EXP Potassium Iodide results in decreased expression of CTNNB1 protein CTD PMID:32593569 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule decreases expression EXP Potassium Iodide results in decreased expression of CXADR mRNA CTD PMID:32593569 NCBI chr11:16,826,269...16,873,564
Ensembl chr11:16,826,399...16,873,562 		JBrowse link
G Cycs cytochrome c, somatic increases expression EXP Potassium Iodide results in increased expression of CYCS protein CTD PMID:32593569 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO [Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of DDIT3 mRNA; Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased expression of DDIT3 protein]
Potassium Iodide results in increased expression of DDIT3 mRNA		 CTD PMID:24231001 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO [Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of ERN1 mRNA; Potassium Iodide promotes the reaction [Sodium Fluoride results in increased expression of ERN1 protein] CTD PMID:24231001 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [bisphenol A co-treated with diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of ESR1 protein; [Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein CTD PMID:29050248 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G F11r F11 receptor decreases expression EXP Potassium Iodide results in decreased expression of F11R protein CTD PMID:32593569 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612 		JBrowse link
G Fn1 fibronectin 1 decreases expression EXP Potassium Iodide results in decreased expression of FN1 mRNA CTD PMID:32593569 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Fst follistatin increases expression EXP Potassium Iodide results in increased expression of FST protein CTD PMID:32593569 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression EXP Potassium Iodide results in decreased expression of HMOX1 protein CTD PMID:32593569 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased expression of HSPA5 mRNA]; Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased expression of HSPA5 protein] CTD PMID:24231001 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression EXP Potassium Iodide results in decreased expression of ITGB1 protein CTD PMID:32593569 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression EXP Potassium Iodide results in decreased expression of KIT mRNA; Potassium Iodide results in decreased expression of KIT protein CTD PMID:32593569 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
G Marveld2 MARVEL domain containing 2 decreases expression EXP Potassium Iodide results in decreased expression of MARVELD2 protein CTD PMID:32593569 NCBI chr 2:30,612,746...30,634,308
Ensembl chr 2:30,612,106...30,634,243 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression EXP Potassium Iodide results in decreased expression of NFE2L2 protein CTD PMID:32593569 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Ocln occludin decreases expression EXP Potassium Iodide results in decreased expression of OCLN mRNA CTD PMID:32593569 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions EXP Potassium Iodide inhibits the reaction [Propylthiouracil results in increased expression of and results in increased activity of ODC1 protein] CTD PMID:8882155 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression EXP Potassium Iodide results in increased expression of PARP1 protein modified form CTD PMID:32593569 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
decreases expression		 EXP [Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of PCNA protein
Potassium Iodide results in decreased expression of PCNA protein		 CTD PMID:29050248 PMID:32593569 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 ISO Potassium Iodide inhibits the reaction [arsenic trioxide results in increased expression of PTGS2 mRNA]; Potassium Iodide inhibits the reaction [arsenic trioxide results in increased expression of PTGS2 protein]; Potassium Iodide inhibits the reaction [monomethylarsonous acid results in increased expression of PTGS2 mRNA]
Potassium Iodide results in decreased expression of PTGS2 protein		 CTD PMID:18588940 PMID:19014992 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression EXP Potassium Iodide results in decreased expression of PTK2 protein; Potassium Iodide results in decreased expression of PTK2 protein modified form CTD PMID:32593569 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression EXP Potassium Iodide results in increased expression of SOD1 protein CTD PMID:32593569 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO Potassium Iodide inhibits the reaction [monomethylarsonous acid results in increased expression of SOD2 protein] CTD PMID:18588940 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression		 ISO 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA]; 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 protein]
Potassium Iodide results in increased expression of SQSTM1 mRNA; Potassium Iodide results in increased expression of SQSTM1 protein		 CTD PMID:29923297 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Potassium Iodide inhibits the reaction [monomethylarsonous acid results in increased phosphorylation of SRC protein] CTD PMID:18588940 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Testin testin gene decreases expression EXP Potassium Iodide results in decreased expression of TESTIN mRNA CTD PMID:32593569 NCBI chr17:4,194,796...4,225,376
Ensembl chr17:4,212,890...4,225,376 		JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP Potassium Iodide results in decreased expression of TJP1 mRNA CTD PMID:32593569 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469 		JBrowse link
G Tp53 tumor protein p53 increases expression EXP Potassium Iodide results in increased expression of TP53 protein CTD PMID:32593569 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP [diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of TSHB protein CTD PMID:29050248 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681 		JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased splicing of XBP1 mRNA] CTD PMID:24231001 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19840
    role 19790
      chemical role 19308
        antioxidant 14233
          radical scavenger 5211
            potassium iodide 44
Path 2
Term Annotations click to browse term
  CHEBI ontology 19840
    subatomic particle 19838
      composite particle 19838
        hadron 19838
          baryon 19838
            nucleon 19838
              atomic nucleus 19838
                atom 19838
                  main group element atom 19730
                    main group molecular entity 19730
                      s-block molecular entity 19481
                        alkali metal molecular entity 10600
                          potassium molecular entity 4618
                            elemental potassium 4618
                              potassium(1+) 4618
                                potassium salt 4618
                                  potassium iodide 44
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