CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: alachlor
Accession: CHEBI:2533
browse the term
Definition: An aromatic amide that is N-(2,6-diethylphenyl)acetamide substituted by a methoxymethyl group at at the nitrogen atom while one of the hydrogens of the methyl group has been replaced by a chlorine atom.
Synonyms: exact_synonym: 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide
related_synonym: 2-Chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide; Alachlore; Chloressigsaeure-N-(methoxymethyl)-2,6-diaethylanilid; Formula=C14H20ClNO2; InChI=1S/C14H20ClNO2/c1-4-11-7-6-8-12(5-2)14(11)16(10-18-3)13(17)9-15/h6-8H,4-5,9-10H2,1-3H3; InChIKey=XCSGPAVHZFQHGE-UHFFFAOYSA-N; SMILES=CCc1cccc(CC)c1N(COC)C(=O)CCl
xref: Beilstein:2944476; CAS:15972-60-8; HMDB:HMDB0031766; KEGG:C10928; LINCS:LSM-19972
xref_mesh: MESH:C000188
xref: PMID:11807927; PMID:23599414; PPDB:17; Pesticides:alachlor; Reaxys:2944476
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Abcb1a
ATP binding cassette subfamily B member 1A
multiple interactions increases activity
ISO
ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel] alachlor results in increased activity of ABCB1 protein
CTD
PMID:18433974
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Ache
acetylcholinesterase
increases activity increases expression
ISO EXP
alachlor results in increased activity of ACHE protein alachlor results in increased expression of ACHE mRNA
CTD
PMID:12419858 PMID:16998629
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Acsm4
acyl-CoA synthetase medium-chain family member 4
affects expression
EXP
alachlor affects the expression of ACSM4 mRNA
CTD
PMID:19425180
NCBI chr 1:174,053,931...174,078,345
Ensembl chr 1:174,053,931...174,078,341
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Adarb1
adenosine deaminase, RNA-specific, B1
increases expression
EXP
alachlor results in increased expression of ADARB1 mRNA
CTD
PMID:12419858
NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852
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Adh7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
affects expression
EXP
alachlor affects the expression of ADH7 mRNA
CTD
PMID:19425180
NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
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Aen
apoptosis enhancing nuclease
affects expression
EXP
alachlor affects the expression of AEN mRNA
CTD
PMID:19425180
NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
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Ago2
argonaute RISC catalytic component 2
increases expression
EXP
alachlor results in increased expression of AGO2 mRNA
CTD
PMID:12419858
NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
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Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein
CTD
PMID:19883720
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alpl
alkaline phosphatase, biomineralization associated
multiple interactions
ISO
alachlor inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA]
CTD
PMID:29149346
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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Apod
apolipoprotein D
affects expression
EXP
alachlor affects the expression of APOD mRNA
CTD
PMID:19425180
NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
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Ar
androgen receptor
multiple interactions
ISO
alachlor inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [alachlor results in increased activity of AR protein]
CTD
PMID:15064155 PMID:18324785
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arhgap35
Rho GTPase activating protein 35
affects expression
EXP
alachlor affects the expression of ARHGAP35 mRNA
CTD
PMID:19425180
NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298
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Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
increases expression
EXP
alachlor results in increased expression of ATIC mRNA
CTD
PMID:12419858
NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
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Bax
BCL2 associated X, apoptosis regulator
increases expression
EXP
alachlor results in increased expression of BAX mRNA
CTD
PMID:12419858
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
increases expression multiple interactions decreases response to substance
ISO
alachlor results in increased expression of BCL2 protein fulvestrant inhibits the reaction [alachlor results in increased expression of BCL2 protein]; PK 11195 inhibits the reaction [BCL2 protein results in decreased susceptibility to alachlor]
CTD
PMID:10545406 PMID:12730627
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bin1
bridging integrator 1
increases expression
EXP
alachlor results in increased expression of BIN1 mRNA
CTD
PMID:12419858
NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
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Calca
calcitonin-related polypeptide alpha
increases expression
EXP
alachlor results in increased expression of CALCA mRNA
CTD
PMID:12419858
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Car2
carbonic anhydrase 2
increases expression
EXP
alachlor results in increased expression of CA2 mRNA
CTD
PMID:12419858
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Ccnb1
cyclin B1
increases expression
EXP
alachlor results in increased expression of CCNB1 mRNA
CTD
PMID:12419858
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccnd1
cyclin D1
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein
CTD
PMID:19883720
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccnd2
cyclin D2
increases expression
EXP
alachlor results in increased expression of CCND2 mRNA
CTD
PMID:12419858
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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Cd200
Cd200 molecule
increases expression
EXP
alachlor results in increased expression of CD200 mRNA
CTD
PMID:12419858
NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
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Cdc123
cell division cycle 123
increases expression
EXP
alachlor results in increased expression of CDC123 mRNA
CTD
PMID:12419858
NCBI chr17:72,459,270...72,503,316
Ensembl chr17:72,459,282...72,503,316
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Cdk1
cyclin-dependent kinase 1
increases expression
EXP
alachlor results in increased expression of CDK1 mRNA
CTD
PMID:12419858
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Ces5a
carboxylesterase 5A
affects expression
EXP
alachlor affects the expression of CES5A mRNA
CTD
PMID:19425180
NCBI chr19:11,469,431...11,499,007
Ensembl chr19:11,469,469...11,499,006
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Cgref1
cell growth regulator with EF hand domain 1
increases expression
EXP
alachlor results in increased expression of CGREF1 mRNA
CTD
PMID:12419858
NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
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Clip2
CAP-GLY domain containing linker protein 2
increases expression
EXP
alachlor results in increased expression of CLIP2 mRNA
CTD
PMID:12419858
NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023
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Col11a1
collagen type XI alpha 1 chain
increases expression
EXP
alachlor results in increased expression of COL11A1 mRNA
CTD
PMID:12419858
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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Col5a1
collagen type V alpha 1 chain
increases expression
EXP
alachlor results in increased expression of COL5A1 mRNA
CTD
PMID:12419858
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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Col5a2
collagen type V alpha 2 chain
increases expression
EXP
alachlor results in increased expression of COL5A2 mRNA
CTD
PMID:12419858
NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
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Cplx2
complexin 2
increases expression
EXP
alachlor results in increased expression of CPLX2 mRNA
CTD
PMID:12419858
NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
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Cpz
carboxypeptidase Z
increases expression
EXP
alachlor results in increased expression of CPZ mRNA
CTD
PMID:12419858
NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945
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Crabp2
cellular retinoic acid binding protein 2
increases expression
EXP
alachlor results in increased expression of CRABP2 mRNA
CTD
PMID:12419858
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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Cxcr4
C-X-C motif chemokine receptor 4
increases expression
EXP
alachlor results in increased expression of CXCR4 mRNA
CTD
PMID:12419858
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
EXP
alachlor results in increased expression of CYP1A1 protein
CTD
PMID:11850968
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
EXP
alachlor results in increased expression of CYP1A2 protein
CTD
PMID:11850968
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp2a3
cytochrome P450, family 2, subfamily a, polypeptide 3
decreases expression
EXP
alachlor results in decreased expression of CYP2A3 protein
CTD
PMID:16698726
NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
multiple interactions
EXP
alachlor results in increased expression of and results in increased activity of CYP2B1 protein
CTD
PMID:11850968
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
increases expression
EXP
alachlor results in increased expression of CYP2B2 protein
CTD
PMID:11850968
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
decreases response to substance
ISO
CYP2B6 protein results in decreased susceptibility to alachlor
CTD
PMID:16277416
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases metabolic processing increases expression multiple interactions
ISO
CYP3A4 protein results in increased metabolism of alachlor alachlor results in increased expression of CYP3A4 mRNA [CYP3A4 protein results in increased metabolism of alachlor] which results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamide
CTD
PMID:10475613 PMID:16565514 PMID:18273908
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
increases expression
EXP
alachlor results in increased expression of CYP3A23-3A1 mRNA
CTD
PMID:14613717
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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Defa5
defensin alpha 5
increases expression
EXP
alachlor results in increased expression of DEFA5 mRNA
CTD
PMID:12419858
NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836
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Dmbt1
deleted in malignant brain tumors 1
increases expression
EXP
alachlor results in increased expression of DMBT1 mRNA
CTD
PMID:12419858
NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
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Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
increases expression
EXP
alachlor results in increased expression of EIF4EBP1 mRNA
CTD
PMID:12419858
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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Eln
elastin
increases expression
EXP
alachlor results in increased expression of ELN mRNA
CTD
PMID:12419858
NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
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Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
increases expression
EXP
alachlor results in increased expression of ENTPD2 mRNA
CTD
PMID:12419858
NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
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Erp29
endoplasmic reticulum protein 29
increases expression
EXP
alachlor results in increased expression of ERP29 mRNA
CTD
PMID:12419858
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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Esr1
estrogen receptor 1
affects binding multiple interactions
ISO
alachlor binds to ESR1 protein [Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein]; alachlor inhibits the reaction [Estradiol binds to ESR1 protein]
CTD
PMID:9168004 PMID:14579009
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Fdps
farnesyl diphosphate synthase
increases expression
EXP
alachlor results in increased expression of FDPS mRNA
CTD
PMID:12419858
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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Fntb
farnesyltransferase, CAAX box, subunit beta
increases expression
EXP
alachlor results in increased expression of FNTB mRNA
CTD
PMID:12419858
NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
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Foxa2
forkhead box A2
increases expression
EXP
alachlor results in increased expression of FOXA2 mRNA
CTD
PMID:12419858
NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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Fyn
FYN proto-oncogene, Src family tyrosine kinase
increases expression
EXP
alachlor results in increased expression of FYN mRNA
CTD
PMID:12419858
NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
EXP
alachlor results in increased expression of GADD45A mRNA
CTD
PMID:12419858
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
EXP
alachlor results in increased expression of GCLC protein
CTD
PMID:14563481
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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Gclm
glutamate cysteine ligase, modifier subunit
increases expression
EXP
alachlor results in increased expression of GCLM protein
CTD
PMID:14563481
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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Gk
glycerol kinase
affects expression
EXP
alachlor affects the expression of GK mRNA
CTD
PMID:19425180
NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631
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Gng8
G protein subunit gamma 8
increases expression
EXP
alachlor results in increased expression of GNG8 mRNA
CTD
PMID:12419858
NCBI chr 1:77,564,512...77,568,371
Ensembl chr 1:77,564,515...77,568,371
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Gpx6
glutathione peroxidase 6
increases expression
EXP
alachlor results in increased expression of GPX6 mRNA
CTD
PMID:12419858
NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091
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Gsk3b
glycogen synthase kinase 3 beta
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein
CTD
PMID:19883720
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Hbb
hemoglobin subunit beta
affects binding
EXP
alachlor binds to HBB protein
CTD
PMID:10075819
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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Hdc
histidine decarboxylase
increases expression
EXP
alachlor results in increased expression of HDC mRNA
CTD
PMID:12419858
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
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Hmgb2
high mobility group box 2
increases expression
EXP
alachlor results in increased expression of HMGB2 mRNA
CTD
PMID:12419858
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
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Hmox1
heme oxygenase 1
increases expression
EXP
alachlor results in increased expression of HMOX1 mRNA
CTD
PMID:12419858
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
increases expression
EXP
alachlor results in increased expression of HNRNPA1 mRNA
CTD
PMID:12419858
NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
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Homer2
homer scaffold protein 2
increases expression
EXP
alachlor results in increased expression of HOMER2 mRNA
CTD
PMID:12419858
NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
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Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
EXP
alachlor results in increased expression of HSP90AA1 mRNA alternative form
CTD
PMID:8792849
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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Ifnb1
interferon beta 1
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein]
CTD
PMID:15907790 PMID:18177342
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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IgG-2a
gamma-2a immunoglobulin heavy chain
affects expression
EXP
alachlor affects the expression of IGG-2A mRNA
CTD
PMID:19425180
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Jchain
joining chain of multimeric IgA and IgM
affects expression
EXP
alachlor affects the expression of JCHAIN mRNA
CTD
PMID:19425180
NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298
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Kif3b
kinesin family member 3B
affects expression
EXP
alachlor affects the expression of KIF3B mRNA
CTD
PMID:19425180
NCBI chr 3:141,758,466...141,798,012
Ensembl chr 3:141,758,466...141,797,963
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Klf6
KLF transcription factor 6
increases expression
EXP
alachlor results in increased expression of KLF6 mRNA
CTD
PMID:12419858
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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Lgals1
galectin 1
increases expression
EXP
alachlor results in increased expression of LGALS1 mRNA
CTD
PMID:12419858
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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Lgi4
leucine-rich repeat LGI family, member 4
affects expression
EXP
alachlor affects the expression of LGI4 mRNA
CTD
PMID:19425180
NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
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Lxn
latexin
increases expression
EXP
alachlor results in increased expression of LXN mRNA
CTD
PMID:12419858
NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460
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Map3k1
mitogen-activated protein kinase kinase kinase 1
increases expression
EXP
alachlor results in increased expression of MAP3K1 mRNA
CTD
PMID:12419858
NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
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Marcks
myristoylated alanine rich protein kinase C substrate
increases expression
EXP
alachlor results in increased expression of MARCKS mRNA
CTD
PMID:12419858
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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Mcm6
minichromosome maintenance complex component 6
increases expression
EXP
alachlor results in increased expression of MCM6 mRNA
CTD
PMID:12419858
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
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Mgat2
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
increases expression
EXP
alachlor results in increased expression of MGAT2 mRNA
CTD
PMID:12419858
NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177
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Mmp2
matrix metallopeptidase 2
increases expression increases activity
EXP
alachlor results in increased expression of MMP2 mRNA alachlor results in increased activity of MMP2 protein
CTD
PMID:12419858 PMID:16178123
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp9
matrix metallopeptidase 9
increases expression
EXP
alachlor results in increased expression of MMP9 mRNA
CTD
PMID:12419858
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Moxd2
monooxygenase, DBH-like 2
affects expression
EXP
alachlor affects the expression of MOXD2 mRNA
CTD
PMID:19425180
NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299
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Mt3
metallothionein 3
increases expression
EXP
alachlor results in increased expression of MT3 mRNA
CTD
PMID:12419858
NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
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Mvd
mevalonate diphosphate decarboxylase
increases expression
EXP
alachlor results in increased expression of MVD mRNA
CTD
PMID:12419858
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Myc
MYC proto-oncogene, bHLH transcription factor
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein
CTD
PMID:19883720
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity
ISO
alachlor results in increased activity of NFE2L2 protein
CTD
PMID:20143881
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; alachlor inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]
CTD
PMID:15907790 PMID:17015962
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
CTD
PMID:15907790
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nfkbib
NFKB inhibitor beta
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein]
CTD
PMID:15907790
NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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Nos2
nitric oxide synthase 2
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD
PMID:15907790
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity multiple interactions
ISO EXP
alachlor results in increased activity of NR1I2 protein alachlor binds to and results in increased activity of NR1I2 protein
CTD
PMID:14613717 PMID:16565514 PMID:21115097
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
increases activity
ISO
alachlor results in increased activity of NR1I3 protein
CTD
PMID:28927721
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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Nr3c2
nuclear receptor subfamily 3, group C, member 2
multiple interactions
ISO
alachlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; alachlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]
CTD
PMID:29149346
NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
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Obp2b
odorant binding protein 2B
increases expression
EXP
alachlor results in increased expression of OBP2B mRNA
CTD
PMID:12419858
NCBI chr 3:8,582,074...8,585,258
Ensembl chr 3:8,582,074...8,585,258
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Or7g31
olfactory receptor family 7 subfamily G member 31
affects expression
EXP
alachlor affects the expression of OR7G2 mRNA
CTD
PMID:19425180
NCBI chr 8:17,056,179...17,057,117
Ensembl chr 8:17,053,661...17,057,239
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Pcolce
procollagen C-endopeptidase enhancer
increases expression
EXP
alachlor results in increased expression of PCOLCE mRNA
CTD
PMID:12419858
NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
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Pcsk6
proprotein convertase subtilisin/kexin type 6
increases expression
EXP
alachlor results in increased expression of PCSK6 mRNA
CTD
PMID:12419858
NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
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Pdk2
pyruvate dehydrogenase kinase 2
increases expression
EXP
alachlor results in increased expression of PDK2 mRNA
CTD
PMID:12419858
NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
G
Pgr
progesterone receptor
multiple interactions affects binding
ISO
alachlor inhibits the reaction [Progesterone binds to PGR protein] alachlor binds to PGR protein
CTD
PMID:14579009
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Phex
phosphate regulating endopeptidase X-linked
increases expression
EXP
alachlor results in increased expression of PHEX mRNA
CTD
PMID:12419858
NCBI chr X:37,607,553...37,856,183
Ensembl chr X:37,610,760...37,854,469
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Plp1
proteolipid protein 1
affects expression
EXP
alachlor affects the expression of PLP1 mRNA
CTD
PMID:19425180
NCBI chr X:100,184,039...100,201,035
Ensembl chr X:100,185,767...100,201,032
G
Polr3g
RNA polymerase III subunit G
affects expression
EXP
alachlor affects the expression of POLR3G mRNA
CTD
PMID:19425180
NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125
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Prph
peripherin
increases expression
EXP
alachlor results in increased expression of PRPH mRNA
CTD
PMID:12419858
NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136
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Ptgds
prostaglandin D2 synthase
affects expression
EXP
alachlor affects the expression of PTGDS mRNA
CTD
PMID:19425180
NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
G
Ptgr1
prostaglandin reductase 1
increases expression
EXP
alachlor results in increased expression of PTGR1 mRNA
CTD
PMID:12419858
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
G
Ptk2b
protein tyrosine kinase 2 beta
multiple interactions
ISO
[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form
CTD
PMID:19883720
NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
G
Qdpr
quinoid dihydropteridine reductase
increases expression
EXP
alachlor results in increased expression of QDPR mRNA
CTD
PMID:12419858
NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
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Qprt
quinolinate phosphoribosyltransferase
affects expression
EXP
alachlor affects the expression of QPRT mRNA
CTD
PMID:19425180
NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
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Rassf8
Ras association domain family member 8
affects expression
EXP
alachlor affects the expression of RASSF8 mRNA
CTD
PMID:19425180
NCBI chr 4:178,716,110...178,798,042
Ensembl chr 4:178,719,992...178,796,690
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
alachlor inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]
CTD
PMID:15907790
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Rnf138
ring finger protein 138
affects expression
EXP
alachlor affects the expression of RNF138 mRNA
CTD
PMID:19425180
NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930
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RT1-DMa
RT1 class II, locus DMa
increases expression
EXP
alachlor results in increased expression of HLA-DMA mRNA
CTD
PMID:12419858
NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
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S100a8
S100 calcium binding protein A8
increases expression
EXP
alachlor results in increased expression of S100A8 mRNA
CTD
PMID:12419858
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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S100a9
S100 calcium binding protein A9
increases expression
EXP
alachlor results in increased expression of S100A9 mRNA
CTD
PMID:12419858
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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Scrg1
stimulator of chondrogenesis 1
affects expression
EXP
alachlor affects the expression of SCRG1 mRNA
CTD
PMID:19425180
NCBI chr16:32,760,028...32,788,299
Ensembl chr16:32,760,028...32,788,299
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Sec24c
SEC24 homolog C, COPII coat complex component
affects expression
EXP
alachlor affects the expression of SEC24C mRNA
CTD
PMID:19425180
NCBI chr15:3,602,460...3,624,524
Ensembl chr15:3,602,460...3,624,422
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Serpinb11
serpin family B member 11
affects expression
EXP
alachlor affects the expression of SERPINB11 mRNA
CTD
PMID:19425180
NCBI chr13:23,304,775...23,344,604
Ensembl chr13:23,304,456...23,344,604
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Serpinh1
serpin family H member 1
increases expression
EXP
alachlor results in increased expression of SERPINH1 mRNA
CTD
PMID:12419858
NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
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Slc16a1
solute carrier family 16 member 1
increases expression
EXP
alachlor results in increased expression of SLC16A1 mRNA
CTD
PMID:12419858
NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
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Slc22a20
solute carrier family 22 member 20
affects expression
EXP
alachlor affects the expression of SLC22A20 mRNA
CTD
PMID:19425180
NCBI chr 1:203,257,374...203,273,854
Ensembl chr 1:203,257,374...203,273,822
G
Slc25a35
solute carrier family 25, member 35
affects expression
EXP
alachlor affects the expression of SLC25A35 mRNA
CTD
PMID:19425180
NCBI chr10:53,672,851...53,677,501
Ensembl chr10:53,673,340...53,698,160
G
Slc4a2
solute carrier family 4 member 2
increases expression
EXP
alachlor results in increased expression of SLC4A2 mRNA
CTD
PMID:12419858
NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965
G
Slc6a13
solute carrier family 6 member 13
affects expression
EXP
alachlor affects the expression of SLC6A13 mRNA
CTD
PMID:19425180
NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152
G
Slc7a1
solute carrier family 7 member 1
increases expression
EXP
alachlor results in increased expression of SLC7A1 mRNA
CTD
PMID:12419858
NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
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Snrpn
small nuclear ribonucleoprotein polypeptide N
affects expression
EXP
alachlor affects the expression of SNRPN mRNA
CTD
PMID:19425180
NCBI chr 1:111,101,327...111,123,400
Ensembl chr 1:111,101,329...111,123,634
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Snurf
SNRPN upstream open reading frame
affects expression
EXP
alachlor affects the expression of SNURF mRNA
CTD
PMID:19425180
NCBI chr 1:111,101,327...111,123,634
Ensembl chr 1:111,101,329...111,123,634
G
Sox11
SRY-box transcription factor 11
increases expression
EXP
alachlor results in increased expression of SOX11 mRNA
CTD
PMID:12419858
NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
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Srpx
sushi-repeat-containing protein, X-linked
increases expression
EXP
alachlor results in increased expression of SRPX mRNA
CTD
PMID:12419858
NCBI chr X:12,676,984...12,751,296
Ensembl chr X:12,566,645...12,747,882
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Tfrc
transferrin receptor
increases expression
EXP
alachlor results in increased expression of TFRC mRNA
CTD
PMID:12419858
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
EXP
alachlor results in increased expression of TIMP1 mRNA
CTD
PMID:12419858
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Tnc
tenascin C
increases expression
EXP
alachlor results in increased expression of TNC mRNA
CTD
PMID:12419858
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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Tnf
tumor necrosis factor
multiple interactions
ISO
alachlor promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD
PMID:15256756
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Top2a
DNA topoisomerase II alpha
increases expression
EXP
alachlor results in increased expression of TOP2A mRNA
CTD
PMID:12419858
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
G
Tshb
thyroid stimulating hormone subunit beta
increases expression
EXP
alachlor results in increased expression of TSHB protein
CTD
PMID:8812207
NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
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