Lgi4 (leucine-rich repeat LGI family, member 4)

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Gene: Lgi4 (leucine-rich repeat LGI family, member 4) Rattus norvegicus

Analyze

Symbol:

Lgi4

Name:

leucine-rich repeat LGI family, member 4

RGD ID:

735035

Description:

Predicted to be involved in adult locomotory behavior; neurogenesis; and regulation of myelination. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in childhood absence epilepsy. Orthologous to human LGI4 (leucine rich repeat LGI family member 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

leucine-rich repeat LGI family member 4

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	86,294,539 - 86,305,909 (+)	NCBI
Rnor_6.0 Ensembl	1	89,491,654 - 89,502,974 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	89,491,588 - 89,502,939 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	90,647,194 - 90,656,996 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	86,103,249 - 86,113,051 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	86,181,359 - 86,191,160 (+)	NCBI
Celera	1	80,664,083 - 80,673,885 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

childhood absence epilepsy (ISO)

dystonia (ISO)

fetal akinesia deformation sequence syndrome 1 (ISO)

Neurogenic Arthrogryposis Multiplex Congenita 1 with Myelin Defect (ISO)

Neurogenic Arthrogryposis Multiplex Congenita 2 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5-triiodo-L-thyronine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

alachlor (EXP)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

carbon nanotube (ISO)

clothianidin (ISO)

endosulfan (EXP)

ethanol (ISO)

furan (EXP)

ketamine (EXP)

manganese(II) chloride (EXP)

nickel atom (ISO)

obeticholic acid (ISO)

paracetamol (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

silver atom (ISO)

silver(0) (ISO)

Soman (EXP)

sunitinib (ISO)

triclosan (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult locomotory behavior (ISO)

glial cell development (ISO)

glial cell proliferation (ISO)

gliogenesis (ISO)

myelination (ISO)

myelination in peripheral nervous system (ISO)

neuron maturation (ISO)

regulation of myelination (ISO)

Schwann cell development (ISO)

Cellular Component

extracellular space (ISO)

Molecular Function

protein binding (ISO)

References

References - curated


1.	Gu W, etal., Neurogenetics 2004 Feb;5(1):41-4. Epub 2003 Sep 19.
2.	RGD automated data pipeline
3.	RGD automated import pipeline for gene-chemical interactions
4.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:1652607	PMID:9671673	PMID:15282162	PMID:16341215	PMID:20220021	PMID:21068328	PMID:28318499

Genomics

Comparative Map Data

Lgi4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	86,294,539 - 86,305,909 (+)	NCBI
Rnor_6.0 Ensembl	1	89,491,654 - 89,502,974 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	89,491,588 - 89,502,939 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	90,647,194 - 90,656,996 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	86,103,249 - 86,113,051 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	86,181,359 - 86,191,160 (+)	NCBI
Celera	1	80,664,083 - 80,673,885 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

LGI4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	19	35,124,513 - 35,142,451 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	19	35,124,513 - 35,135,059 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	19	35,615,417 - 35,625,963 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	19	35,615,417 - 35,626,178 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	40,307,257 - 40,317,944 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	40,307,256 - 40,317,944	NCBI
Celera	19	32,328,853 - 32,339,614 (-)	NCBI
Cytogenetic Map	19	q13.12	NCBI
HuRef	19	32,123,410 - 32,134,089 (-)	NCBI		HuRef
CHM1_1	19	35,617,430 - 35,628,191 (-)	NCBI		CHM1_1

Lgi4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	30,758,360 - 30,770,360 (+)	NCBI	GRCm39		mm39
GRCm38	7	31,058,909 - 31,070,935 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	31,059,342 - 31,070,935 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	31,844,954 - 31,855,954 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	30,768,695 - 30,779,695 (+)	NCBI			mm8
Celera	7	25,627,425 - 25,637,643 (+)	NCBI		Celera
Cytogenetic Map	7	B1	NCBI
cM Map	7	19.29	NCBI

Lgi4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	4,445,155 - 4,453,610 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	4,441,808 - 4,456,884 (-)	NCBI	ChiLan1.0	ChiLan1.0

LGI4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	40,808,853 - 40,827,023 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	40,808,847 - 40,827,024 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	32,070,563 - 32,082,273 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

LGI4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	1	117,444,941 - 117,452,381 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	1	117,443,569 - 117,452,367 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Lgi4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936570	1,122,987 - 1,131,270 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LGI4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	44,655,617 - 44,663,234 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	44,655,621 - 44,663,874 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	40,101,147 - 40,110,225 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LGI4
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	30,057,248 - 30,075,435 (-)	NCBI
ChlSab1.1 Ensembl	6	30,057,917 - 30,067,696 (-)	Ensembl

Lgi4
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624794	8,358,671 - 8,384,763 (+)	NCBI

Position Markers

RH131077

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	89,501,640 - 89,501,837	NCBI	Rnor6.0
Rnor_5.0	1	90,656,730 - 90,656,927	UniSTS	Rnor5.0
RGSC_v3.4	1	86,112,785 - 86,112,982	UniSTS	RGSC3.4
Celera	1	80,673,619 - 80,673,816	UniSTS
RH 3.4 Map	1	845.3	UniSTS
Cytogenetic Map	1	q21	UniSTS

BE105369

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	89,500,664 - 89,500,849	NCBI	Rnor6.0
Rnor_5.0	1	90,655,754 - 90,655,939	UniSTS	Rnor5.0
RGSC_v3.4	1	86,111,809 - 86,111,994	UniSTS	RGSC3.4
Celera	1	80,672,643 - 80,672,828	UniSTS
RH 3.4 Map	1	843.7	UniSTS
Cytogenetic Map	1	q21	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5655769	122614963	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	23406428	108057505	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	25951907	130917265	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34993530	173445086	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	35377508	94364229	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	35377692	217372257	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43579208	126240667	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43579208	126240667	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43579208	126240667	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43579208	126240667	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43579208	126240667	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	cortical volumetric bone mineral density (CMO:0001730)	1	43579208	126240667	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43579208	126240667	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	49147799	156446783	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49578577	94578577	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49578577	169852184	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49578693	217054291	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	50522714	94225616	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	57761301	104391981	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	58209327	103209327	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	58354072	161711996	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	64588516	125875986	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	66113339	122614963	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	67227683	94201552	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	79134941	113593716	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	79689548	124689548	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	79689765	94909507	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	82788437	239853971	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	83502376	128502376	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	83656882	126240667	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	85779320	130779320	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	85917265	130917265	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	86776571	131776571	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	88634585	106002500	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	191
Count of miRNA genes:	147
Interacting mature miRNAs:	159
Transcripts:	ENSRNOT00000028632
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									28		2
Low	3	31	18	2	19	2	8	11	46	20	39	11	8
Below cutoff		12	19	19		19				15

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_199499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC111870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC064659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000028632 ⟹ ENSRNOP00000028632

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	89,491,654 - 89,502,974 (+)	Ensembl

RefSeq Acc Id:

NM_199499 ⟹ NP_955793

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	86,295,074 - 86,304,876 (+)	NCBI
Rnor_6.0	1	89,492,104 - 89,501,906 (+)	NCBI
Rnor_5.0	1	90,647,194 - 90,656,996 (+)	NCBI
RGSC_v3.4	1	86,103,249 - 86,113,051 (+)	RGD
Celera	1	80,664,083 - 80,673,885 (+)	RGD

Sequence:

show sequence

GAGAATAATAGAAAGATAGGGAGAGAAAGATACTGATAGAAAATCCACACTCCAGATACTGGAA
GAGGGGCACAGGCTGGAGGAGGGAACAAGGTCAGCCAGCCACAGGACAGCATGGCCAGCAGCAG
GATGGAGGGGCATCCCACAGAGATGTAGTGGTTCAGGTCTGGCAGGGTGGAGCCAGGGGGAGCC
TGGGCTGGGGCAGGGGCATGGGAGGGGCAGGCATTCTGTTGTTCCTGTTGGCCTGGACTGGGGC
AGGAGTGTCCTGGAGTCCCCCCAAGGGAAAGTGTCCTCCACGCTGCTCCTGCTCCAAGGAGAGC
ACCCTGTGTGAGGGCTCCCCCGAGCTGCCTGAGAGCTTCTCCACCACGCTCCTGTCACTCTCTC
TCGTCAGGATGGGGGTCTCCCGGCTGAAGGCTGGAAGCTTTTTAAAGATGCCGTCACTGCACTT
GCTCCTCTTCACGTCCAATACCTTCTCTGTAATTGAGGGTGATGCCTTCATCGGCCTGTCCTAC
CTGCAGTACCTCTTCATTGAGGACAACAAGATCGGCTCCATCTCTAAGAACGCCCTGAGGGGAC
TCCGCTCACTGACCCACCTAAGCCTGGCCAACAACCACCTTGAGGCTCTACCCAGATTCCTGTT
CCAAGGCTTGGAGACTCTGACTCATGTGGACCTCCGTGGTAACCCGTTCCAGTGTGACTGCCGA
GTACTTTGGTTGCTACAGTGGATGCCTATGGTGAATGCCAGTGTGGGCACGGGGGCCTGTGCGG
GCCCCTCTGCACTTGCTCAAATACAACTGAATCACCTCGACCCTAAGAAGTTCAAGTGTAAAGC
CACAGAACTCTCCTGGCTCCAGACTGTTGGGGAGTCGGCACTGAGCGTGGAGTCCTTCTCCTAT
CAGGGGGAACCTCACATGGTCCTGGCACAGCCCTTCGCTGGCCGTTGCCTGATCCTGGTGTGGG
ACTACAGCCTGCAGCGCTTCAGGTCTGAGGAAGAGCTGTCCGCGCCCTCAGTGGTGTCCTGCAA
ACCTCTGGTGCTGGGCCCACGCCTCTTCATACTGGCTGCTCGCCTATGGGGAGGCTCACAGCTG
TGGTCACGGTCCAGCCCCGACCTGCGTCTGACCCCTGTGCAAGTCCTAGCCCCTCAACGGCTGC
TGCGACCCAATGATGCCGAGCTCCTGTGGCTGGATGGGCAGCCCTGCTTCGTGGTGGCTGATGC
TTCCAAGGCTGGCAGCACCACGCTGCTGTGTCGTGATGGGCCGGGCTTCTACCCACGCCAGAGC
CTGCACGCCTGGCACCGCGACACCGATGCAGAGGCCCTGGAGCTGGACGGCCGACCGCACCTGT
TGCTTGCTTCCGCCTCCCAGAGGCCTGTGCTCTTTCACTGGTTTGGTGGCCGATTCGAGAGGCG
CACAGACATCCCAGAGGCAGAGGACGTCTATGCCACAAAACACTTTCAGGCGGGAGGAGACGTG
TTCCTGTGCCTGACTCGATACATTGGGGACTCCATGGTCATGCGCTGGGACGGCTCCATGTTCC
GTCTGCTGCAGCAACTTCCATCTCGAGGCTCCCATGTCTTCCAGCCACTACTAATTGCCAGCGA
CCAGTTGGCCATTCTGGGCAGCGACTTCGCCTTCAGCCAAGTCTTCCGCTTTGAGCCCGATAAA
GGGATCCTGGAGCCACTACAGGAGCTGGGCCCACCGGCCTTGGTGGCCCCCCGAGCCTTTGGCC
AAGTCACTGTAGCAGGAAGACGCTTTTTATTCGCAGCGTGCTTCAAGGGGCCCACGCAGATCTA
CCAGCACCATGAGTTGGATCTCAGTGCCTGAGGCTGGGAAAGACCCTGGAAGTGGCTATGGGAC
TGGCAAGGGCATTCTGGGACATCTGGGTAACCTCTCTGGGCTGGCCTCCTGGATGTCACAGACA
GTCCTGGGTGATACAGACCACAAGCCAAGTGCATCAGCCTGAGTTAGGCTTAGTCCACTTTTCG
GAGGATCTGTACCTAAGGGGCAAGTGGGAGGTCTCTTTACTCCCAACTATGTTTAGGGCCCCTC
CAGTCTGAAGCCACATTTGGGCTGAGGACAGATGCTCCCATGCACAACATCTTGGGAGTTCCTC
CTGGAACACAACTTGGAGCTGGGATACAGAAACTAAAAGGGCAATCTGCTGAGCTCCAAGAGGT
TTGGACACCCCGCCCTCAACGTCCCCTTGGTCCTGCTGCATATAAAGAACCGAGAGAGAGCATT
AGTTCCACTCAAACCCTATCTGGCCATTGGTTTCGTGGAGTATGCGTCTCTGTGACGTCACAGT
TGCTGGGCAGTTTCTTGGCCTGGTACTCTGCTGCCTGTGCGCATGCCTGGTACTTTGCTGCCCG
TGCGCATGTCTATTTCCGAAGACTGATTGCTTTTACACGTGTGCAGTAAAAGTGAAGCAGCGAA
GATGAAGTCTAGAGGCGTCACAGAGAGCACTGGGTACCTTTTTCCAGAATGTGACAGGGGCAAG
AACAGGGAGTGTATGAATTCAATAAATGCCCCGCGCACCCAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAA

hide sequence

RefSeq Acc Id:

XM_008759169 ⟹ XP_008757391

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	89,491,588 - 89,502,939 (+)	NCBI

Sequence:

show sequence

CCAGTGGCTTCTCCTCCTAGCCCTCCCATCTGCAGTCTGCAGAGCCATCTGGTCTCCACCCTGG
GGACATCCTTCCCACTCTCCCTAACTGGGGTTGAGTGGGGACTCTGATGAGGGGGTTGGTTGGG
AGTGCTTAGGGTGGCAGGCTTGGCAGCCCCGCCCCCTCAAAGGCCATTCAATTTCTTTCCTGGG
CCTTTTCTTCCGATGGCCCCTGACCTCCTCCTTCCTACCCTTCTGCTGGGCACATCCCAGGCCA
CAGAAAGTGAGACCAGCGTGGGAGGACACACAGAAAGTACTGGAAACTTGAAACGGGGCAGGGA
GGTGAGAGTTACAGACAGACCAGGCAGAAGGACCAGGACAGACAGGCAGACAGACAGACAGACA
GACAGACAGACAGACAGACACACACACACACACACACACACACACACACACACACACACACACA
CCCCAGAGATCTACAGGCCAAACCAGAGAGACAAAGACAGAAAGACAGAGATCGCAGAGTGTGG
GAAAGAGAATAATAGAAAGATAGGGAGAGAAAGATACTGATAGAAAATCCACACTCCAGATACT
GGAAGAGAGGCACAGGCTGGAGGAGGGAACAAGGTCAGCCAGCCACAGGACAGCATGGCCAGCA
GCAGGATGGAGGGGCATCCCACAGAGATGTAGTGGTTCAGGTCTGGCAGGGTGGAGCCAGGGGG
AGCCTGGGCTGGGGCAGGGGCATGGGAGGGGCAGGCATTCTGTTGTTCCTGTTGGCCTGGACTG
GGGCAGGAGTGTCCTGGAGTCCCCCCAAGGGAAAGTGTCCTCCACGCTGCTCCTGCTCCAAGGA
GAGCACCCTGTGTGAGGGCTCCCCCGAGCTGCCTGAGAGCTTCTCCACCACGCTCCTGTCACTC
TCTCTCGTCAGGATGGGGGTCTCCCGGCTGAAGGCTGGAAGCTTTTTAAAGATGCCGTCACTGC
ACTTGCTCTTCATTGAGGACAACAAGATCGGCTCCATCTCTAAGAACGCCCTGAGGGGACTCCG
CTCACTGACCCACCTAAGCCTGGCCAACAACCACCTTGAGGCTCTACCCAGATTCCTGTTCCAA
GGCTTGGAGACTCTGACTCATGTGGACCTCCGTGGTAACCCGTTCCAGTGTGACTGCCGAGTAC
TTTGGTTGCTACAGTGGATGCCTATGGTGAATGCCAGTGTGGGCACGGGGGCCTGTGCGGGCCC
CTCTGCACTTGCTCAAATACAACTGAATCACCTCGACCCTAAGAAGTTCAAGTGTAAAGCCACA
GAACTCTCCTGGCTCCAGACTGTTGGGGAGTCGGCACTGAGCGTGGAGTCCTTCTCCTATCAGG
GGGAACCTCACATGGTCCTGGCACAGCCCTTCGCTGGCCGTTGCCTGATCCTGGTGTGGGACTA
CAGCCTGCAGCGCTTCAGGTCTGAGGAAGAGCTGTCCGCGCCCTCAGTGGTGTCCTGCAAACCT
CTGGTGCTGGGCCCACGCCTCTTCATACTGGCTGCTCGCCTATGGGGAGGCTCACAGCTGTGGT
CACGGTCCAGCCCCGACCTGCGTCTGACCCCTGTGCAAGTCCTAGCCCCTCAACGGCTGCTGCG
ACCCAATGATGCCGAGCTCCTGTGGCTGGATGGGCAGCCCTGCTTCGTGGTGGCTGATGCTTCC
AAGGCTGGCAGCACCACGCTGCTGTGTCGTGATGGGCCGGGCTTCTACCCACGCCAGAGCCTGC
ACGCCTGGCACCGCGACACCGATGCAGAGGCCCTGGAGCTGGACGGCCGACCGCACCTGTTGCT
TGCTTCCGCCTCCCAGAGGCCTGTGCTCTTTCACTGGTTTGGTGGCCGATTCGAGAGGCGCACA
GACATCCCAGAGGCAGAGGACGTCTATGCCACAAAACACTTTCAGGCGGGAGGAGACGTGTTCC
TGTGCCTGACTCGATACATTGGGGACTCCATGGTCATGCGCTGGGACGGCTCCATGTTCCGTCT
GCTGCAGCAACTTCCATCTCGAGGCTCCCATGTCTTCCAGCCACTACTAATTGCCAGCGACCAG
TTGGCCATTCTGGGCAGCGACTTCGCCTTCAGCCAAGTCTTCCGCTTTGAGCCCGATAAAGGGA
TCCTGGAGCCACTACAGGAGCTGGGCCCACCGGCCTTGGTGGCCCCCCGAGCCTTTGGCCAAGT
CACTGTAGCAGGAAGACGCTTTTTATTCGCAGCGTGCTTCAAGGGGCCCACGCAGATCTACCAG
CACCATGAGTTGGATCTCAGTGCCTGAGGCTGGGAAAGACCCTGGAAGTGGCTATGGGACTGGC
AAGGGCATTCTGGGACATCTGGGTAACCTCTCTGGGCTGGCCTCCTGGATGTCACAGACAGTCC
TGGGTGATACAGACCACAAGCCAAGTGCATCAGCCTGAGTTAGGCTTAGTCCACTTTTCGGAGG
ATCTGTACCTAAGGGGCAAGTGGGAGGTCTCTTTACTCCCAACTATGTTTAGGGCCCCTCCAGT
CTGAAGCCACATTTGGGCTGAGGACAGATGCTCCCATGCACAACATCTTGGGAGTTCCTCCTGG
AACACAACTTGGAGCTGGGATACAGAAACTAAAAGGGCAATCTGCTGAGCTCCAAGAGGTTTGG
ACACCCCGCCCTCAACGTCCCCTTGGTCCTGCTGCATATAAAGAACCGAGAGAGAGCATTAGTT
CCACTCAAACCCTATCTGGCCATTGGTTTCGTGGAGTATGCGTCTCTGTGACGTCACAGTTGCT
GGGCAGTTTCTTGGCCTGGTACTCTGCTGCCTGTGCGCATGCCTGGTACTTTGCTGCCCGTGCG
CATGTCTATTTCCGAAGACTGATTGCTTTTACACGTGTGCAGTAAAAGTGAAGCAGCGAAGATG
AAGTCTAGAGGCGTCACAGAGAGCACTGGGTACCTTTTTCCAGAATGTGACAGGGGCAAGAACA
GGGAGTGTATGAATTCAATAAATGCCCCGCGCACCCAACCTGCCCGCTCTGTGGTCTCAAGGCG
GGAGCCTCTTGTTGAGTGGCAGGTGAAAACCCTGGATGGGATCTTGGGCAGGAATTTTGGTTTG
AAAGGTTTTAGGCATTTTCTGTGATTGCACTTAGATTCTGGAGGCTCTGATGGATACTGAGGAG
CCTCAAGAGAGCTGGGGGTCAGTGGAGGATCTCACAGTGTGGCCACTGCTGGACTATCGGCGGT
GTTCTGAGAAATTACAGGTCTCACAGGTGAATGGAAGGGTCTCATGATAAAGTGGGGTCATCTC
AACTGCAGGGGTGGGGACAGCTAAATATCGGGGTGGCCCCAATATGGTGTGATGACCCCACGGT
GTAGTTTTTCGCAATGTCACCCAGTGTCCCTACACTGCGTGAGATTAGGGCTCTTTTTCACTCC
CGCAAGTGTCCCTCGTTTGCCACTAGAACTTAAGTGGCACAGGAGGCTGCCCATGGAGGGAAAG
GGCAAATCTCATGCCCACCATAAGGCCATGACGTGCAGGTCTAAGCATGATTCAGCCATCAGCT
CCTGCTCATTAACCTGCCCCATCGAGGCCCCAAGGTCCACCCCAGCATCTGCTCACCTCCTCGC
TGCCGGCAGCCACACTCCAAGCTCCACACAGAGTCTCTGGCTCGCCTGAGCATGACGTAAAATC
ATTTTATATTAACAACTGAACAAAGAACCTGCTACCATGAGATGAGGCTCGGGGAAGGCAGTGT
CAGGAGAGGAGGAGCCCAGACATCTTGGAGTTCAAGCCCATCTCCAGAGACAGGACCTGCACTT
TTTTAACTGATCCATCCTCAGCAGTTGTGAGCAGAGCCTGGTAGAGGGAATGGAGTCAGTTTGC
AAGCATCTCCCCTTTCCTTCTCCCTGACTCAGGCACGCTCCCACTCCAGCTTCCACTAGTGACC
ATTACCCCCACGTGTCACCCCCAATCATCCTGTGTCATACCTGGTGTGATGAGGGGTGGCCCAT
CTCCTGGACGGTGGCTAAGGAAATAAACGGAATAATATGTAAATAAA

hide sequence

RefSeq Acc Id:

XM_008759170 ⟹ XP_008757392

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	89,492,529 - 89,502,939 (+)	NCBI

Sequence:

show sequence

AGACTCCGGGATTTGGGGTGGGGTGCCGAGGTCTCTCAGAATCTTGGACACCAAAAGAATTCTG
GGCTGTCTGAAAGATTTGGAAAGCTCTCTCGTCAGGATGGGGGTCTCCCGGCTGAAGGCTGGAA
GCTTTTTAAAGATGCCGTCACTGCACTTGCTCCTCTTCACGTCCAATACCTTCTCTGTAATTGA
GGGTGATGCCTTCATCGGCCTGTCCTACCTGCAGTACCTCTTCATTGAGGACAACAAGATCGGC
TCCATCTCTAAGAACGCCCTGAGGGGACTCCGCTCACTGACCCACCTAAGCCTGGCCAACAACC
ACCTTGAGGCTCTACCCAGATTCCTGTTCCAAGGCTTGGAGACTCTGACTCATGTGGACCTCCG
TGGTAACCCGTTCCAGTGTGACTGCCGAGTACTTTGGTTGCTACAGTGGATGCCTATGGTGAAT
GCCAGTGTGGGCACGGGGGCCTGTGCGGGCCCCTCTGCACTTGCTCAAATACAACTGAATCACC
TCGACCCTAAGAAGTTCAAGTGTAAAGCCACAGAACTCTCCTGGCTCCAGACTGTTGGGGAGTC
GGCACTGAGCGTGGAGTCCTTCTCCTATCAGGGGGAACCTCACATGGTCCTGGCACAGCCCTTC
GCTGGCCGTTGCCTGATCCTGGTGTGGGACTACAGCCTGCAGCGCTTCAGGTCTGAGGAAGAGC
TGTCCGCGCCCTCAGTGGTGTCCTGCAAACCTCTGGTGCTGGGCCCACGCCTCTTCATACTGGC
TGCTCGCCTATGGGGAGGCTCACAGCTGTGGTCACGGTCCAGCCCCGACCTGCGTCTGACCCCT
GTGCAAGTCCTAGCCCCTCAACGGCTGCTGCGACCCAATGATGCCGAGCTCCTGTGGCTGGATG
GGCAGCCCTGCTTCGTGGTGGCTGATGCTTCCAAGGCTGGCAGCACCACGCTGCTGTGTCGTGA
TGGGCCGGGCTTCTACCCACGCCAGAGCCTGCACGCCTGGCACCGCGACACCGATGCAGAGGCC
CTGGAGCTGGACGGCCGACCGCACCTGTTGCTTGCTTCCGCCTCCCAGAGGCCTGTGCTCTTTC
ACTGGTTTGGTGGCCGATTCGAGAGGCGCACAGACATCCCAGAGGCAGAGGACGTCTATGCCAC
AAAACACTTTCAGGCGGGAGGAGACGTGTTCCTGTGCCTGACTCGATACATTGGGGACTCCATG
GTCATGCGCTGGGACGGCTCCATGTTCCGTCTGCTGCAGCAACTTCCATCTCGAGGCTCCCATG
TCTTCCAGCCACTACTAATTGCCAGCGACCAGTTGGCCATTCTGGGCAGCGACTTCGCCTTCAG
CCAAGTCTTCCGCTTTGAGCCCGATAAAGGGATCCTGGAGCCACTACAGGAGCTGGGCCCACCG
GCCTTGGTGGCCCCCCGAGCCTTTGGCCAAGTCACTGTAGCAGGAAGACGCTTTTTATTCGCAG
CGTGCTTCAAGGGGCCCACGCAGATCTACCAGCACCATGAGTTGGATCTCAGTGCCTGAGGCTG
GGAAAGACCCTGGAAGTGGCTATGGGACTGGCAAGGGCATTCTGGGACATCTGGGTAACCTCTC
TGGGCTGGCCTCCTGGATGTCACAGACAGTCCTGGGTGATACAGACCACAAGCCAAGTGCATCA
GCCTGAGTTAGGCTTAGTCCACTTTTCGGAGGATCTGTACCTAAGGGGCAAGTGGGAGGTCTCT
TTACTCCCAACTATGTTTAGGGCCCCTCCAGTCTGAAGCCACATTTGGGCTGAGGACAGATGCT
CCCATGCACAACATCTTGGGAGTTCCTCCTGGAACACAACTTGGAGCTGGGATACAGAAACTAA
AAGGGCAATCTGCTGAGCTCCAAGAGGTTTGGACACCCCGCCCTCAACGTCCCCTTGGTCCTGC
TGCATATAAAGAACCGAGAGAGAGCATTAGTTCCACTCAAACCCTATCTGGCCATTGGTTTCGT
GGAGTATGCGTCTCTGTGACGTCACAGTTGCTGGGCAGTTTCTTGGCCTGGTACTCTGCTGCCT
GTGCGCATGCCTGGTACTTTGCTGCCCGTGCGCATGTCTATTTCCGAAGACTGATTGCTTTTAC
ACGTGTGCAGTAAAAGTGAAGCAGCGAAGATGAAGTCTAGAGGCGTCACAGAGAGCACTGGGTA
CCTTTTTCCAGAATGTGACAGGGGCAAGAACAGGGAGTGTATGAATTCAATAAATGCCCCGCGC
ACCCAACCTGCCCGCTCTGTGGTCTCAAGGCGGGAGCCTCTTGTTGAGTGGCAGGTGAAAACCC
TGGATGGGATCTTGGGCAGGAATTTTGGTTTGAAAGGTTTTAGGCATTTTCTGTGATTGCACTT
AGATTCTGGAGGCTCTGATGGATACTGAGGAGCCTCAAGAGAGCTGGGGGTCAGTGGAGGATCT
CACAGTGTGGCCACTGCTGGACTATCGGCGGTGTTCTGAGAAATTACAGGTCTCACAGGTGAAT
GGAAGGGTCTCATGATAAAGTGGGGTCATCTCAACTGCAGGGGTGGGGACAGCTAAATATCGGG
GTGGCCCCAATATGGTGTGATGACCCCACGGTGTAGTTTTTCGCAATGTCACCCAGTGTCCCTA
CACTGCGTGAGATTAGGGCTCTTTTTCACTCCCGCAAGTGTCCCTCGTTTGCCACTAGAACTTA
AGTGGCACAGGAGGCTGCCCATGGAGGGAAAGGGCAAATCTCATGCCCACCATAAGGCCATGAC
GTGCAGGTCTAAGCATGATTCAGCCATCAGCTCCTGCTCATTAACCTGCCCCATCGAGGCCCCA
AGGTCCACCCCAGCATCTGCTCACCTCCTCGCTGCCGGCAGCCACACTCCAAGCTCCACACAGA
GTCTCTGGCTCGCCTGAGCATGACGTAAAATCATTTTATATTAACAACTGAACAAAGAACCTGC
TACCATGAGATGAGGCTCGGGGAAGGCAGTGTCAGGAGAGGAGGAGCCCAGACATCTTGGAGTT
CAAGCCCATCTCCAGAGACAGGACCTGCACTTTTTTAACTGATCCATCCTCAGCAGTTGTGAGC
AGAGCCTGGTAGAGGGAATGGAGTCAGTTTGCAAGCATCTCCCCTTTCCTTCTCCCTGACTCAG
GCACGCTCCCACTCCAGCTTCCACTAGTGACCATTACCCCCACGTGTCACCCCCAATCATCCTG
TGTCATACCTGGTGTGATGAGGGGTGGCCCATCTCCTGGACGGTGGCTAAGGAAATAAACGGAA
TAATATGTAAATAAA

hide sequence

RefSeq Acc Id:

XM_039081995 ⟹ XP_038937923

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	86,294,539 - 86,305,909 (+)	NCBI

RefSeq Acc Id:

XM_039081997 ⟹ XP_038937925

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	86,296,362 - 86,305,909 (+)	NCBI

RefSeq Acc Id:

XM_039082002 ⟹ XP_038937930

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	86,296,362 - 86,305,909 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_955793	(Get FASTA)	NCBI Sequence Viewer
	XP_038937923	(Get FASTA)	NCBI Sequence Viewer
	XP_038937925	(Get FASTA)	NCBI Sequence Viewer
	XP_038937930	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH64659	(Get FASTA)	NCBI Sequence Viewer
	EDM07669	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_955793 ⟸ NM_199499
- Peptide Label:	precursor
- UniProtKB:	Q6P2A4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGGAGILLFLLAWTGAGVSWSPPKGKCPPRCSCSKESTLCEGSPELPESFSTTLLSLSLVRMGV SRLKAGSFLKMPSLHLLLFTSNTFSVIEGDAFIGLSYLQYLFIEDNKIGSISKNALRGLRSLTH LSLANNHLEALPRFLFQGLETLTHVDLRGNPFQCDCRVLWLLQWMPMVNASVGTGACAGPSALA QIQLNHLDPKKFKCKATELSWLQTVGESALSVESFSYQGEPHMVLAQPFAGRCLILVWDYSLQR FRSEEELSAPSVVSCKPLVLGPRLFILAARLWGGSQLWSRSSPDLRLTPVQVLAPQRLLRPNDA ELLWLDGQPCFVVADASKAGSTTLLCRDGPGFYPRQSLHAWHRDTDAEALELDGRPHLLLASAS QRPVLFHWFGGRFERRTDIPEAEDVYATKHFQAGGDVFLCLTRYIGDSMVMRWDGSMFRLLQQL PSRGSHVFQPLLIASDQLAILGSDFAFSQVFRFEPDKGILEPLQELGPPALVAPRAFGQVTVAG RRFLFAACFKGPTQIYQHHELDLSA hide sequence

RefSeq Acc Id:

XP_008757391 ⟸ XM_008759169

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGGAGILLFLLAWTGAGVSWSPPKGKCPPRCSCSKESTLCEGSPELPESFSTTLLSLSLVRMGV
SRLKAGSFLKMPSLHLLFIEDNKIGSISKNALRGLRSLTHLSLANNHLEALPRFLFQGLETLTH
VDLRGNPFQCDCRVLWLLQWMPMVNASVGTGACAGPSALAQIQLNHLDPKKFKCKATELSWLQT
VGESALSVESFSYQGEPHMVLAQPFAGRCLILVWDYSLQRFRSEEELSAPSVVSCKPLVLGPRL
FILAARLWGGSQLWSRSSPDLRLTPVQVLAPQRLLRPNDAELLWLDGQPCFVVADASKAGSTTL
LCRDGPGFYPRQSLHAWHRDTDAEALELDGRPHLLLASASQRPVLFHWFGGRFERRTDIPEAED
VYATKHFQAGGDVFLCLTRYIGDSMVMRWDGSMFRLLQQLPSRGSHVFQPLLIASDQLAILGSD
FAFSQVFRFEPDKGILEPLQELGPPALVAPRAFGQVTVAGRRFLFAACFKGPTQIYQHHELDLS
A

hide sequence

RefSeq Acc Id:

XP_008757392 ⟸ XM_008759170

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGVSRLKAGSFLKMPSLHLLLFTSNTFSVIEGDAFIGLSYLQYLFIEDNKIGSISKNALRGLRS
LTHLSLANNHLEALPRFLFQGLETLTHVDLRGNPFQCDCRVLWLLQWMPMVNASVGTGACAGPS
ALAQIQLNHLDPKKFKCKATELSWLQTVGESALSVESFSYQGEPHMVLAQPFAGRCLILVWDYS
LQRFRSEEELSAPSVVSCKPLVLGPRLFILAARLWGGSQLWSRSSPDLRLTPVQVLAPQRLLRP
NDAELLWLDGQPCFVVADASKAGSTTLLCRDGPGFYPRQSLHAWHRDTDAEALELDGRPHLLLA
SASQRPVLFHWFGGRFERRTDIPEAEDVYATKHFQAGGDVFLCLTRYIGDSMVMRWDGSMFRLL
QQLPSRGSHVFQPLLIASDQLAILGSDFAFSQVFRFEPDKGILEPLQELGPPALVAPRAFGQVT
VAGRRFLFAACFKGPTQIYQHHELDLSA

hide sequence

RefSeq Acc Id:

ENSRNOP00000028632 ⟸ ENSRNOT00000028632

RefSeq Acc Id:	XP_038937923 ⟸ XM_039081995
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038937925 ⟸ XM_039081997
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038937930 ⟸ XM_039082002
- Peptide Label:	isoform X2

Protein Domains

LRRCT

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689943

Promoter ID:

EPDNEW_R468

Type:

single initiation site

Name:

Lgi4_1

Description:

leucine-rich repeat LGI family, member 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	89,491,626 - 89,491,686	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:735035	AgrOrtholog
Ensembl Genes	ENSRNOG00000021087	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000028632	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000028632	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5623799	IMAGE-MGC_LOAD
InterPro	Cys-rich_flank_reg_C	UniProtKB/TrEMBL
	EAR	UniProtKB/TrEMBL
	EPTP	UniProtKB/TrEMBL
	L_dom-like	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
KEGG Report	rno:361549	UniProtKB/TrEMBL
MGC_CLONE	MGC:72559	IMAGE-MGC_LOAD
NCBI Gene	361549	ENTREZGENE
Pfam	EPTP	UniProtKB/TrEMBL
	LRR_8	UniProtKB/TrEMBL
PhenoGen	Lgi4	PhenoGen
PROSITE	EAR	UniProtKB/TrEMBL
	LRR	UniProtKB/TrEMBL
SMART	LRR_TYP	UniProtKB/TrEMBL
	LRRCT	UniProtKB/TrEMBL
UniProt	Q6P2A4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Lgi4	leucine-rich repeat LGI family, member 4			Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM