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ONTOLOGY REPORT - ANNOTATIONS

Term:osteoclast differentiation
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Accession:GO:0030316 term browser browse the term
Definition:The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
Synonyms:exact_synonym: osteoclast cell differentiation


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osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant IEP RGD PMID:19361364 RGD:2315902 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of ISO (PMID:21490954) RGD PMID:21490954 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA		 (PMID:27860183)
GO_REF:0000107		 RGD
Ensembl		 PMID:27860183 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Calcr calcitonin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:7664679)		 Ensembl
RGD		 PMID:7664679 GO_REF:0000107 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392 		JBrowse link
G Car2 carbonic anhydrase 2 TAS RGD PMID:9665810 RGD:1342423 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 HEP RGD PMID:16304045 RGD:151665775 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 HEP RGD PMID:16304045 RGD:151665775 NCBI chr10:68,380,185...68,385,859
Ensembl chr10:68,380,188...68,384,001 		JBrowse link
G Ccn4 cellular communication network factor 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5788182|PMID:25864198)		 Ensembl
RGD		 PMID:25864198 GO_REF:0000107 MGI:5788182 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 HEP RGD PMID:16304045 RGD:151665775 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd300lf Cd300 molecule-like family member F acts_upstream_of_or_within ISO (PMID:14662855) RGD PMID:14662855 NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex acts_upstream_of_or_within ISO MGI:104798|MGI:1100089|MGI:1857735 (PMID:15485831) RGD PMID:15485831 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 acts_upstream_of ISO (PMID:23395171) RGD PMID:23395171 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA
IEA		 (PMID:17442941)
MGI:1100089|MGI:1856333 (PMID:17053831), (PMID:9215625)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000104
(PMID:18606301)		 RGD
GO_Central
Ensembl
UniProt		 PMID:9215625 PMID:17053831 PMID:17442941 PMID:18606301 PMID:12379742 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107, RGD:628338 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISS
IBA
HEP
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(MGI:4835629|PMID:20504948), (MGI:5294299|PMID:17121910), (MGI:5294540|PMID:18814279)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:17121910 PMID:18814279 PMID:20504948 PMID:16304045 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:4835629 MGI:5294299 MGI:5294540, RGD:151665775 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1858008 (PMID:15866165)
MGI:2148567|MGI:3041864 (PMID:15866165)		 Ensembl
RGD		 PMID:15866165 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 HEP RGD PMID:16304045 RGD:151665775 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in ISO (MGI:3510294|PMID:15452179) RGD PMID:15452179 MGI:3510294 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078 		JBrowse link
G Efna2 ephrin A2 involved_in ISO
IBA		 (MGI:5284751|PMID:19299512)
GO_REF:0000033		 RGD
GO_Central		 PMID:19299512 GO_REF:0000033 MGI:5284751 NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:5607149 (PMID:29533727) RGD PMID:29533727 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (MGI:5284751|PMID:19299512) RGD PMID:19299512 MGI:5284751 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Farp2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 involved_in ISO (MGI:4844210|PMID:20702777) RGD PMID:20702777 MGI:4844210 NCBI chr 9:94,053,650...94,161,982
Ensembl chr 9:94,053,726...94,162,212 		JBrowse link
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:1857165 (PMID:21841309) RGD PMID:21841309 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit acts_upstream_of ISO (PMID:23395171) RGD PMID:23395171 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18548006)		 Ensembl
RGD		 PMID:18548006 GO_REF:0000107 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:18799727) RGD PMID:18799727 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Gab2 GRB2-associated binding protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3575591|PMID:15750601)
GO_REF:0000107
(PMID:15750601)		 UniProt
RGD
Ensembl		 PMID:15750601 GO_REF:0000024 GO_REF:0000107 MGI:3575591 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Glo1 glyoxalase 1 involved_in ISO (MGI:5526937|PMID:18695250) RGD PMID:18695250 MGI:5526937 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649 		JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2159355 (PMID:15936336)		 Ensembl
RGD		 PMID:15936336 GO_REF:0000107 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5750254|PMID:26438360)		 UniProt
RGD		 PMID:26438360 GO_REF:0000024 MGI:5750254 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559 		JBrowse link
G Iapp islet amyloid polypeptide acts_upstream_of ISO MGI:1346858|MGI:2656235 (PMID:14970190) RGD PMID:14970190 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within ISO (PMID:35733270) RGD PMID:35733270 NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024 		JBrowse link
G Igsf23 immunoglobulin superfamily, member 23 involved_in ISO (PMID:31560140) RGD PMID:31560140 NCBI chr 1:79,591,059...79,606,323
Ensembl chr 1:79,592,088...79,610,438 		JBrowse link
G Il20 interleukin 20 acts_upstream_of ISO (PMID:21844205) RGD PMID:21844205 NCBI chr13:42,380,981...42,384,625
Ensembl chr13:42,380,981...42,384,625 		JBrowse link
G Ireb2 iron responsive element binding protein 2 involved_in ISO
IEA		 (MGI:3838421|PMID:19252502)
GO_REF:0000107		 RGD
Ensembl		 PMID:19252502 GO_REF:0000107 MGI:3838421 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:14769860) RGD PMID:14769860 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5306313|PMID:15304486)		 Ensembl
RGD		 PMID:15304486 GO_REF:0000107 MGI:5306313 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mitf melanocyte inducing transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO
IEP		 GO_REF:0000107
MGI:1856095 (PMID:12086670)		 Ensembl
RGD		 PMID:12086670 PMID:22576626 GO_REF:0000107, RGD:151667429 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:1100089|MGI:1339753|MGI:97583 (PMID:17053831)		 Ensembl
RGD		 PMID:17053831 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2158925 (PMID:21982707) RGD PMID:21982707 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nfix nuclear factor I X acts_upstream_of_or_within ISO (PMID:31740002) RGD PMID:31740002 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Oscar osteoclast associated Ig-like receptor acts_upstream_of_or_within ISO (PMID:21841309)
MGI:1277211|MGI:5301430|MGI:98725 (PMID:21841309)		 RGD PMID:21841309 NCBI chr 1:65,607,214...65,615,395
Ensembl chr 1:65,607,410...65,613,758 		JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1856885 (PMID:12627228)		 GO_Central
RGD		 PMID:12627228 GO_REF:0000033 NCBI chr20:46,071,657...46,187,049
Ensembl chr20:46,153,075...46,187,023 		JBrowse link
G Pf4 platelet factor 4 HEP RGD PMID:16304045 RGD:151665775 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:97306 (PMID:17053831)		 Ensembl
RGD		 PMID:17053831 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Sbno2 strawberry notch homolog 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:5551983 (PMID:23980096)		 GO_Central
RGD		 PMID:23980096 GO_REF:0000033 NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:3045799 (PMID:14976225)		 Ensembl
RGD		 PMID:14976225 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3826297|PMID:18971331)
(PMID:34668226)		 UniProt
RGD		 PMID:18971331 PMID:34668226 GO_REF:0000024 MGI:3826297 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Snx10 sorting nexin 10 involved_in ISO (MGI:5317512|PMID:22174188) RGD PMID:22174188 MGI:5317512 NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:80,612,669...80,676,996 		JBrowse link
G Spi1 Spi-1 proto-oncogene IEP RGD PMID:22576626 RGD:151667429 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 acts_upstream_of_or_within ISO MGI:1856973|MGI:5496553 (PMID:18768394), (PMID:21305608), (PMID:22245629), (PMID:23166162), (PMID:23908015) RGD PMID:18768394 PMID:21305608 PMID:22245629 PMID:23166162 PMID:23908015 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742 		JBrowse link
G Tf transferrin involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:2179720 (PMID:21841309) RGD PMID:21841309 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tmem64 transmembrane protein 64 acts_upstream_of ISO MGI:3880885 (PMID:23395171) RGD PMID:23395171 NCBI chr 5:28,698,947...28,745,384
Ensembl chr 5:28,698,918...28,745,330 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO MGI:1100089|MGI:99484 (PMID:15485831) RGD PMID:15485831 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in ISO
IEP		 (PMID:18606301) RGD PMID:18606301 PMID:22576626 RGD:151667429 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in
acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:18606301)
MGI:1339753 (PMID:15724149), (PMID:17053831)
MGI:104798|MGI:99484 (PMID:14662855), (PMID:15485831), (PMID:17442941)
(MGI:3575591|PMID:15750601)		 RGD PMID:14662855 PMID:15485831 PMID:15724149 PMID:15750601 PMID:17053831 More... MGI:3575591 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tob2 transducer of ERBB2, 2 acts_upstream_of ISO MGI:3789484 (PMID:18358842) RGD PMID:18358842 NCBI chr 7:113,362,703...113,371,423
Ensembl chr 7:113,361,148...113,372,688 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA		 (MGI:2181820|PMID:10421844)
GO_REF:0000107		 RGD
Ensembl		 PMID:10421844 GO_REF:0000107 MGI:2181820 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:12925681)
(PMID:21841309)		 RGD PMID:12925681 PMID:21841309 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp acts_upstream_of_or_within ISO (PMID:21841309)
MGI:2179720|MGI:2450834 (PMID:21841309)		 RGD PMID:21841309 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
multinuclear osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ocstamp osteoclast stimulatory transmembrane protein involved_in ISO (MGI:5426132|PMID:20882308) RGD PMID:20882308 MGI:5426132 NCBI chr 3:154,131,113...154,141,611
Ensembl chr 3:154,132,328...154,136,991 		JBrowse link
G Oscar osteoclast associated Ig-like receptor acts_upstream_of_or_within ISO (PMID:11805147) RGD PMID:11805147 NCBI chr 1:65,607,214...65,615,395
Ensembl chr 1:65,607,410...65,613,758 		JBrowse link
G Sbno2 strawberry notch homolog 2 acts_upstream_of_or_within ISO MGI:5551983 (PMID:23980096) RGD PMID:23980096 NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:11805147)		 GO_Central
RGD		 PMID:11805147 GO_REF:0000033 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
negative regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn18 claudin 18 acts_upstream_of_or_within ISO MGI:5007067 (PMID:22437732) RGD PMID:22437732 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351 		JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:24039232)
(MGI:5795811|PMID:24039232)		 RGD PMID:24039232 MGI:5795811 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:29149593)
(MGI:6106664|PMID:29149593)		 RGD PMID:29149593 MGI:6106664 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Tjp2 tight junction protein 2 acts_upstream_of_or_within ISO (PMID:22437732) RGD PMID:22437732 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
negative regulation of osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10822112) RGD PMID:10822112 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO
ISS		 (PMID:21403648)
GO_REF:0000024		 RGD
UniProt		 PMID:21403648 GO_REF:0000024 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:25490771) RGD PMID:25490771 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Clec2d C-type lectin domain family 2, member D acts_upstream_of_or_within ISO (PMID:12374791) RGD PMID:12374791 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2148567|MGI:3041864 (PMID:15866165)		 Ensembl
RGD		 PMID:15866165 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Erfe erythroferrone acts_upstream_of ISS
ISO		 GO_REF:0000024
(MGI:6712200|PMID:34002695)		 UniProt
RGD		 PMID:34002695 GO_REF:0000024 MGI:6712200 NCBI chr 9:91,956,971...91,964,846
Ensembl chr 9:91,956,977...91,964,846 		JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:24039232)
(MGI:5795811|PMID:24039232)		 RGD PMID:24039232 MGI:5795811 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889 		JBrowse link
G Fstl3 follistatin like 3 involved_in ISO
IEA		 (PMID:15574124)
GO_REF:0000107		 RGD
Ensembl		 PMID:15574124 GO_REF:0000107 NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639 		JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:204,129,636...204,132,622
Ensembl chr 1:204,129,636...204,133,082 		JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in ISO
IBA		 (MGI:6362357|PMID:31173907)
GO_REF:0000033		 RGD
GO_Central		 PMID:31173907 GO_REF:0000033 MGI:6362357 NCBI chr17:86,003,635...86,041,841
Ensembl chr17:85,966,921...86,041,835 		JBrowse link
G Gpr55 G protein-coupled receptor 55 involved_in ISO (PMID:19805329) RGD PMID:19805329 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613 		JBrowse link
G Iapp islet amyloid polypeptide acts_upstream_of_or_within ISO MGI:1346858|MGI:2656235 (PMID:14970190) RGD PMID:14970190 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Ifnb1 interferon beta 1 acts_upstream_of_or_within ISO (PMID:17442941) RGD PMID:17442941 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:17442941) RGD PMID:17442941 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12941478), (PMID:17442941) RGD PMID:12941478 PMID:17442941 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO MGI:102469|MGI:1100089 (PMID:21982707) RGD PMID:21982707 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386884 (PMID:12161749)		 Ensembl
RGD		 PMID:12161749 GO_REF:0000107 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18802077) RGD PMID:18802077 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Lrrc17 leucine rich repeat containing 17 involved_in ISO (MGI:3850892|PMID:19336404) RGD PMID:19336404 MGI:3850892 NCBI chr 4:13,501,428...13,531,845
Ensembl chr 4:13,501,436...13,531,845 		JBrowse link
G Mafb MAF bZIP transcription factor B involved_in ISS
ISO		 GO_REF:0000024
(MGI:3849531|PMID:19440205)		 UniProt
RGD		 PMID:19440205 GO_REF:0000024 MGI:3849531 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1100089|MGI:1339753|MGI:97583 (PMID:17053831)		 Ensembl
RGD		 PMID:17053831 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:17442941)		 Ensembl
RGD		 PMID:17442941 GO_REF:0000107 NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97306 (PMID:17053831)		 Ensembl
RGD		 PMID:17053831 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pilrb1 paired immunoglobin-like type 2 receptor beta 1 involved_in ISO (MGI:3819877|PMID:18802077) RGD PMID:18802077 MGI:3819877 NCBI chr12:18,516,161...18,525,375
Ensembl chr12:18,516,156...18,525,346 		JBrowse link
G Pirb paired Ig-like receptor B involved_in ISO (PMID:18802077) RGD PMID:18802077 NCBI chr 1:65,499,195...65,506,666
Ensembl chr 1:65,499,195...65,506,666 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA		 MGI:3045799 (PMID:14976225)
GO_REF:0000107		 RGD
Ensembl		 PMID:14976225 PMID:17540629 GO_REF:0000107, RGD:4107086 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Tcta T-cell leukemia translocation altered involved_in ISO (PMID:19560569) RGD PMID:19560569 NCBI chr 8:108,988,588...108,992,324
Ensembl chr 8:108,988,590...108,991,564 		JBrowse link
G Tmem178a transmembrane protein 178A involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(MGI:5706679|PMID:26644563)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:26644563 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5706679 NCBI chr 6:14,004,629...14,063,677
Ensembl chr 6:14,004,630...14,063,549 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 involved_in ISO (PMID:18586671) RGD PMID:18586671 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B involved_in
acts_upstream_of_or_within		 ISO (MGI:6810809|PMID:9168977)
(PMID:29415886)		 RGD PMID:9168977 PMID:29415886 MGI:6810809 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tob2 transducer of ERBB2, 2 acts_upstream_of_or_within ISO MGI:3789484 (PMID:18358842) RGD PMID:18358842 NCBI chr 7:113,362,703...113,371,423
Ensembl chr 7:113,361,148...113,372,688 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (PMID:23149425) RGD PMID:23149425 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:7961821) RGD PMID:7961821 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 involved_in ISO
ISS		 (MGI:5575464|PMID:22467241)
GO_REF:0000024		 RGD
CAFA		 PMID:22467241 GO_REF:0000024 MGI:5575464 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:18799727) RGD PMID:18799727 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of ISO MGI:3849457 (PMID:19479052) RGD PMID:19479052 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089 		JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 acts_upstream_of_or_within ISO MGI:5568128|MGI:98397 (PMID:23526378) RGD PMID:23526378 NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734 		JBrowse link
G Mir34a microRNA 34a acts_upstream_of_or_within_negative_effect ISO (PMID:25043055) RGD PMID:25043055 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of_or_within ISO (PMID:22073305) RGD PMID:22073305 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IEP RGD PMID:7527035 RGD:632779 NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:2142227 (PMID:23526378) RGD PMID:23526378 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21841309)		 Ensembl
RGD		 PMID:21841309 GO_REF:0000107 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
osteoclast fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd109 CD109 molecule acts_upstream_of_or_within ISO (PMID:23593435) RGD PMID:23593435 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194 		JBrowse link
G Cd81 Cd81 molecule involved_in ISS
ISO		 GO_REF:0000024
(MGI:2663571|PMID:12796480)		 UniProt
RGD		 PMID:12796480 GO_REF:0000024 MGI:2663571 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in
acts_upstream_of_or_within		 ISO (MGI:3588832|PMID:16061724), (MGI:5426134|PMID:17164993), (MGI:5426135|PMID:16937266)
(PMID:23980096)		 RGD PMID:16061724 PMID:16937266 PMID:17164993 PMID:23980096 MGI:3588832 MGI:5426134 MGI:5426135 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078 		JBrowse link
G Sbno2 strawberry notch homolog 2 acts_upstream_of_or_within ISO MGI:5551983 (PMID:23980096) RGD PMID:23980096 NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527 		JBrowse link
G Sh3pxd2a SH3 and PX domains 2A involved_in ISO (PMID:22584907) RGD PMID:22584907 NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166 		JBrowse link
G Tcta T-cell leukemia translocation altered involved_in ISO
IBA		 (PMID:19560569)
GO_REF:0000033		 RGD
GO_Central		 PMID:19560569 GO_REF:0000033 NCBI chr 8:108,988,588...108,992,324
Ensembl chr 8:108,988,590...108,991,564 		JBrowse link
osteoclast maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within ISO MGI:2656539|MGI:5428020 (PMID:22615579) RGD PMID:22615579 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
G P2rx5 purinergic receptor P2X 5 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423 		JBrowse link
positive regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO MGI:3849457 (PMID:19479052) RGD PMID:19479052 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089 		JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (MGI:6458683|PMID:30700695) RGD PMID:30700695 MGI:6458683 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Slc9b2 solute carrier family 9 member B2 acts_upstream_of_or_within ISO (PMID:18269914) RGD PMID:18269914 NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18269914), (PMID:22437732), (PMID:23980096)		 Ensembl
RGD		 PMID:18269914 PMID:22437732 PMID:23980096 GO_REF:0000107 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO (MGI:3653295|PMID:14969392) RGD PMID:14969392 MGI:3653295 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
positive regulation of osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) RGD PMID:21490954 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477 		JBrowse link
G Car2 carbonic anhydrase 2 IMP RGD PMID:10523502 RGD:1600711 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 IDA RGD PMID:9920817 RGD:2303108 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IDA RGD PMID:9920817 RGD:2303108 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 IMP RGD PMID:16304045 RGD:151665775 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:123,589,997...123,613,767
Ensembl chr 8:123,589,621...123,612,687 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 acts_upstream_of_or_within ISO (PMID:23395171) RGD PMID:23395171 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Csf1 colony stimulating factor 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:15304486)
MGI:1100089|MGI:1856333 (PMID:15657444), (PMID:17053831), (PMID:21048959), (PMID:9215625)
GO_REF:0000107		 RGD
Ensembl		 PMID:9215625 PMID:15304486 PMID:15657444 PMID:17053831 PMID:21048959 GO_REF:0000107 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:17121910 RGD:2293713 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Eeig1 estrogen-induced osteoclastogenesis regulator 1 involved_in ISO (MGI:6512093|PMID:32741026), (MGI:7444879|PMID:23478294) RGD PMID:23478294 PMID:32741026 MGI:6512093 MGI:7444879 NCBI chr 3:15,822,441...15,854,651
Ensembl chr 3:15,823,144...15,854,643 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:23395171) RGD PMID:23395171 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gnas GNAS complex locus involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3043361 (PMID:15797856)		 Ensembl
RGD		 PMID:15797856 GO_REF:0000107 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:28731198 RGD:13792731 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:16220542) RGD PMID:16220542 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:17888176) RGD PMID:17888176 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il17a interleukin 17A involved_in IEA
ISO		 GO_REF:0000107
(PMID:17888176)		 Ensembl
RGD		 PMID:17888176 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il20 interleukin 20 acts_upstream_of_or_within ISO (PMID:21844205) RGD PMID:21844205 NCBI chr13:42,380,981...42,384,625
Ensembl chr13:42,380,981...42,384,625 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:17888176) RGD PMID:17888176 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Klf10 KLF transcription factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3530069 (PMID:15657444)		 Ensembl
RGD		 PMID:15657444 GO_REF:0000107 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 involved_in ISO (MGI:6252929|PMID:27336669) RGD PMID:27336669 MGI:6252929 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Notch2 notch receptor 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3814108|PMID:18710934)		 Ensembl
RGD		 PMID:18710934 GO_REF:0000107 MGI:3814108 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein involved_in ISO (MGI:5319606|PMID:18064667) RGD PMID:18064667 MGI:5319606 NCBI chr 3:154,131,113...154,141,611
Ensembl chr 3:154,132,328...154,136,991 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5825429|PMID:17668438)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17668438 GO_REF:0000024 GO_REF:0000107 MGI:5825429 NCBI chr15:81,253,714...81,260,057
Ensembl chr15:81,257,781...81,259,728 		JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5825429|PMID:17668438)		 UniProt
RGD		 PMID:17668438 GO_REF:0000024 MGI:5825429 NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta involved_in ISO
IEA		 (MGI:3838421|PMID:19252502)
GO_REF:0000107		 RGD
Ensembl		 PMID:19252502 GO_REF:0000107 MGI:3838421 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(MGI:6869989|PMID:16968888)		 UniProt
RGD		 PMID:16968888 GO_REF:0000024 MGI:6869989 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in ISO (MGI:5822933|PMID:27879318) RGD PMID:27879318 MGI:5822933 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983 		JBrowse link
G Tmem64 transmembrane protein 64 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3880885 (PMID:23395171)		 GO_Central
RGD		 PMID:23395171 GO_REF:0000033 NCBI chr 5:28,698,947...28,745,384
Ensembl chr 5:28,698,918...28,745,330 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:17888176) RGD PMID:17888176 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in ISO (MGI:7444879|PMID:23478294) RGD PMID:23478294 MGI:7444879 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within
involved_in		 IMP
ISO		 MGI:102469|MGI:1339753|MGI:2158925 (PMID:15657444), (PMID:15724149), (PMID:17053831), (PMID:21048959), (PMID:21982707)
(MGI:7444879|PMID:23478294)
(PMID:15304486), (PMID:17241109), (PMID:19560569)		 RGD PMID:15304486 PMID:15657444 PMID:15724149 PMID:17053831 PMID:17241109 More... MGI:7444879, RGD:730134 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA		 (PMID:17135271)
GO_REF:0000107		 RGD
Ensembl		 PMID:17135271 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6294223|PMID:16418779) RGD PMID:16418779 MGI:6294223 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch2 notch receptor 2 involved_in ISO
IEA
ISS		 (PMID:29149593)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29149593 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Siglec15 sialic acid binding Ig-like lectin 15 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1277211 (PMID:22451653)		 GO_Central
RGD		 PMID:22451653 GO_REF:0000033 NCBI chr18:71,506,416...71,521,894
Ensembl chr18:71,505,399...71,521,881 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp acts_upstream_of_or_within ISO MGI:3646642 (PMID:22451653) RGD PMID:22451653 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
regulation of osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 NAS RGD PMID:10423016 RGD:631800 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO MGI:1857966 (PMID:15802266) RGD PMID:15802266 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3849531|PMID:19440205)		 UniProt
Ensembl
RGD		 PMID:19440205 GO_REF:0000024 GO_REF:0000107 MGI:3849531 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO MGI:2148567 (PMID:15802266) RGD PMID:15802266 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Esrra estrogen related receptor, alpha IMP RGD PMID:12193582 RGD:625668 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:2135670 (PMID:20053668) RGD PMID:20053668 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fshb follicle stimulating hormone subunit beta acts_upstream_of_or_within ISO MGI:1857434 (PMID:16630814) RGD PMID:16630814 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO MGI:2384087 (PMID:16630814) RGD PMID:16630814 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Mitf melanocyte inducing transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856085|MGI:98511 (PMID:11930005)		 Ensembl
RGD		 PMID:11930005 GO_REF:0000107 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3849531|PMID:19440205)		 UniProt
Ensembl
RGD		 PMID:19440205 GO_REF:0000024 GO_REF:0000107 MGI:3849531 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Prxl2a peroxiredoxin like 2A involved_in ISO
IEA		 (PMID:19951071)
GO_REF:0000107		 RGD
Ensembl		 PMID:19951071 GO_REF:0000107 NCBI chr16:16,866,601...16,886,378
Ensembl chr16:16,866,603...16,886,433 		JBrowse link
G Rassf2 Ras association domain family member 2 acts_upstream_of_or_within ISO MGI:5314787 (PMID:22227519) RGD PMID:22227519 NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431 		JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 acts_upstream_of_or_within ISO MGI:104554 (PMID:11930005) RGD PMID:11930005 NCBI chr  X:14,729,547...14,742,830
Ensembl chr  X:14,729,550...14,742,571 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:12490655) RGD PMID:12490655 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 acts_upstream_of_or_within ISO (PMID:12490655), (PMID:23395171) RGD PMID:12490655 PMID:23395171 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B involved_in ISO
IBA		 (MGI:5619442|PMID:23149425)
GO_REF:0000033		 RGD
GO_Central		 PMID:23149425 GO_REF:0000033 MGI:5619442 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a IDA RGD PMID:10477728 RGD:633299 NCBI chr 7:8,561,015...8,578,243
Ensembl chr 7:8,563,779...8,576,539 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      cellular developmental process 4695
        cell differentiation 4694
          leukocyte differentiation 674
            myeloid leukocyte differentiation 280
              osteoclast differentiation 136
                multinuclear osteoclast differentiation + 9
                negative regulation of osteoclast differentiation + 35
                osteoclast development + 21
                positive regulation of osteoclast differentiation + 38
                regulation of osteoclast differentiation + 84
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      cellular developmental process 4695
        cell differentiation 4694
          cell development 3269
            hemopoiesis 1061
              myeloid cell differentiation 506
                myeloid leukocyte differentiation 280
                  osteoclast differentiation 136
                    multinuclear osteoclast differentiation + 9
                    negative regulation of osteoclast differentiation + 35
                    osteoclast development + 21
                    positive regulation of osteoclast differentiation + 38
                    regulation of osteoclast differentiation + 84
paths to the root