Oscar (osteoclast associated Ig-like receptor)

Gene: Oscar (osteoclast associated Ig-like receptor) Rattus norvegicus

Analyze

Symbol:

Oscar

Name:

osteoclast associated Ig-like receptor

RGD ID:

1559897

Description:

Predicted to enable collagen receptor activity. Predicted to be involved in immune response-regulating signaling pathway. Predicted to act upstream of or within Fc-gamma receptor signaling pathway; multinuclear osteoclast differentiation; and positive regulation of bone resorption. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Orthologous to human OSCAR (osteoclast associated Ig-like receptor); INTERACTS WITH 3,4-methylenedioxymethamphetamine; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC292537; osteoclast associated receptor; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; RGD1559897; similar to osteoclast-associated receptor mOSCAR-M1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	74,521,626 - 74,529,119 (+)	NCBI		GRCr8
mRatBN7.2	1	65,607,214 - 65,615,395 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	65,607,410 - 65,613,758 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	71,055,647 - 71,061,883 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	79,478,623 - 79,484,859 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	72,805,613 - 72,811,842 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	64,182,174 - 64,188,658 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	64,182,422 - 64,188,658 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	63,173,549 - 63,180,129 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	63,920,506 - 63,925,535 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	63,331,535 - 63,337,783 (+)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alveolar Bone Loss (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

3,4-methylenedioxymethamphetamine (EXP)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

coenzyme Q10 (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diallyl disulfide (ISO)

Diallyl sulfide (ISO)

diarsenic trioxide (ISO)

dioxygen (EXP)

fenthion (ISO)

folic acid (ISO)

formaldehyde (ISO)

genistein (EXP)

hydrogen peroxide (ISO)

lipopolysaccharide (ISO)

methylglyoxal (EXP,ISO)

mono(2-ethylhexyl) phthalate (ISO)

nickel atom (ISO)

niclosamide (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (EXP)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

propanal (ISO)

rotenone (ISO)

silicon dioxide (EXP,ISO)

sodium arsenite (ISO)

triphenyl phosphate (ISO)

tris(2-butoxyethyl) phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

collagen-activated signaling pathway (IEA)

Fc-gamma receptor signaling pathway (ISO)

immune response-regulating signaling pathway (IBA)

multinuclear osteoclast differentiation (ISO)

osteoclast differentiation (ISO)

positive regulation of bone resorption (ISO)

Cellular Component

cell surface (ISO)

plasma membrane (IBA)

Molecular Function

collagen receptor activity (IBA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease.	Brito VGB, etal., Front Pharmacol. 2020 Nov 11;11:579926. doi: 10.3389/fphar.2020.579926. eCollection 2020.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11805147	PMID:15184345	PMID:21841309	PMID:23376485	PMID:23533145

Genomics

Comparative Map Data

Oscar
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	74,521,626 - 74,529,119 (+)	NCBI		GRCr8
mRatBN7.2	1	65,607,214 - 65,615,395 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	65,607,410 - 65,613,758 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	71,055,647 - 71,061,883 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	79,478,623 - 79,484,859 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	72,805,613 - 72,811,842 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	64,182,174 - 64,188,658 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	64,182,422 - 64,188,658 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	63,173,549 - 63,180,129 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	63,920,506 - 63,925,535 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	63,331,535 - 63,337,783 (+)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

OSCAR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	54,094,668 - 54,100,803 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	54,094,668 - 54,102,692 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	54,597,933 - 54,604,094 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	59,289,745 - 59,295,960 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	51,637,613 - 51,643,830 (-)	NCBI		Celera
Cytogenetic Map	19	q13.42	NCBI
HuRef	19	50,913,817 - 50,920,134 (-)	NCBI		HuRef
CHM1_1	19	54,599,687 - 54,605,876 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	57,173,230 - 57,179,492 (-)	NCBI		T2T-CHM13v2.0

Oscar
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	3,612,812 - 3,619,156 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	3,612,812 - 3,619,156 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	3,609,813 - 3,616,157 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	3,609,813 - 3,616,157 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	3,561,415 - 3,567,735 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	3,212,900 - 3,219,220 (-)	NCBI		MGSCv36	mm8
Celera	7	3,520,876 - 3,527,938 (-)	NCBI		Celera
Cytogenetic Map	7	A1	NCBI
cM Map	7	2.08	NCBI

OSCAR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	60,099,494 - 60,105,451 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	62,021,240 - 62,028,314 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	51,027,449 - 51,033,972 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	59,870,810 - 59,873,139 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	59,871,394 - 59,876,370 (-)	Ensembl	panpan1.1		panPan2

OSCAR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	103,101,462 - 103,113,593 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	103,101,819 - 103,106,974 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	103,162,912 - 103,168,962 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	103,746,274 - 103,752,320 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	103,747,000 - 103,752,155 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	103,384,153 - 103,396,647 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	103,145,559 - 103,158,053 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	103,859,686 - 103,865,735 (+)	NCBI		UU_Cfam_GSD_1.0

Oscar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	2,705,658 - 2,711,508 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936994	226,424 - 312,143 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936994	226,318 - 232,143 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OSCAR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	56,022,256 - 56,030,646 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	56,021,434 - 56,029,398 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	53,187,447 - 53,195,643 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OSCAR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	46,772,335 - 46,777,606 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666073	26,859,779 - 26,866,516 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Oscar
72 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	480
Count of miRNA genes:	261
Interacting mature miRNAs:	316
Transcripts:	ENSRNOT00000037943
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	35239598	78430678	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49393172	94393172	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	53895117	82174945	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	35239598	78430678	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	11481312	82174945	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	33449848	78449848	Rat
2302059	Pia36	Pristane induced arthritis QTL 36	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	43333002	88333002	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
1357400	Bw62	Body weight QTL62	4.05		inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	1	22340647	67340647	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	11481312	82174945	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
1300167	Hrtrt2	Heart rate QTL 2	4.35		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	11481312	75088344	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	11481312	82174945	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	45803140	78430678	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	28879780	78430678	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	32737273	90665040	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	49361465	82174945	Rat
724520	Bp145	Blood pressure QTL 145	2.1	0.0024	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	20784828	65784828	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	53863041	90532583	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	11481312	82174945	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	34836858	79836858	Rat
738020	Pia8	Pristane induced arthritis QTL 8	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	1	65833076	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	33449848	78449848	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	53895117	82174945	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium
Low	3	7	50	34	19	34	2	3	70	35	35	11	2
Below cutoff		34	7	7		7	6	8	4		6		6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001184973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC103574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000090790 ⟹ ENSRNOP00000071058

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	65,607,410 - 65,613,758 (+)	Ensembl
Rnor_6.0 Ensembl	1	64,182,422 - 64,188,658 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106643 ⟹ ENSRNOP00000087390

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	65,607,553 - 65,613,758 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117841 ⟹ ENSRNOP00000079596

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	65,607,410 - 65,613,758 (+)	Ensembl

RefSeq Acc Id:

NM_001184973 ⟹ NP_001171902

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	74,522,883 - 74,529,119 (+)	NCBI
mRatBN7.2	1	65,607,522 - 65,613,758 (+)	NCBI
Rnor_6.0	1	64,182,422 - 64,188,658 (+)	NCBI
Rnor_5.0	1	63,173,549 - 63,180,129 (+)	NCBI
Celera	1	63,331,535 - 63,337,783 (+)	NCBI

Sequence:

show sequence

TCAGAGGGTAAAAGGCAGGGCCAGCCTTTCCCCAGCTCCACTGAGAGTGCCCGCCATGGTCCTG
TTGCTGATACTCCAGCTGTCTACTCTCTGTGAGCTGTCCCTCCCCTGGCCTGTGTGTCATGCTG
ACTTCACATCACCAGTGCCCCTAGCCTCATACCCCAAGCCATGGCTGGGGGCTCATCCTGCTGC
AATTGTGACTCCTGGAATCAATGTAACTTTGATTTGCCGTGCACCCCAACCTGCCTGGGGATTT
GGACTCTTCAAAACTGGCCTTGCCACCCCTCTGCTCCTCCGGAATGTGTCCATTGGGCTGGCTG
AGTTCTTCCTGGAAAAGGTGACTTCGGTCCAGGAGGGCAGTTATCACTGCCGCTACCGCAAGAC
AGACTGGGGGCCTGGTGTCTGGTCTCAGCCCAGTAATGCTCTGGAACTGCTGGTAACGGATCAG
CTACCCAGACCATCACTGGTGGCAATTCCTGGGCCTGTGGTGGCCCCAGAAACCACTGTAAGCC
TGCGCTGTGCAGGCCGCATACCAGGCATGAGTTTTGCGCTGTACCGCGCGGATGTGGCAACCCC
TCTGCAGTACATCGACTCTGTGCAGCCCTGGGCTGACTTCCTTCTGAACAGCGCGAATGCACCT
GGCACCTACTATTGCTATTACCACACCCCCTCTAGCCCCTATGTGCTATCAGAGCGCAGCCAGC
CACTGGTCATCAGTTCCGAAGGTTCTGGCTCCTTGGACTATACCCAGGGAAACCTCGTGCGTTT
GGGGCTGGCAGGACTGGTCCTCATCTGCTTGGGCATCATAGTTACTTTCGATTGGCACAGCAGG
CGCTCTGCCTTTGTTCGTCTCCTGCCCCAGCAAAACTGGGTATAGGCCTGTGCGATGGGAAGAG
ACTTCCTGGAGACGGACAGAGAAACTGGGACTCTTGGTGACCAGCCCCTCCGGAACACTCTAAG
CTTCCAGACTCCACTGGATTAATTATTCTTCACCTCAGTATTAGGCTTGTTGAAGGATTAAAGG
AAGTGACCGGCCTGTGGTAAATGATGTTCAGTTAATGTTAGTGACCTTGTCCTCCCTTGAAAAC
CTCTATTTCCTTCATGTGTCTTATCTCCACCCCCCCCCACTCCACCTCTCGTTTCTTTCTTCAT
GGCTATGTTGGGATCATAGGTTCATTCTACCACACCCAGCAAAATATATAGTTACGTATTTTAA
GGGATGATACGCATGCCTCAGCCTGTGTGCAAAGGTGAAAAGACAACTTCCAGGAATTGATTTT
CTCTGTCCATCCTGTGGGTCCCAGGGTTTGAACTCAGACTGTTAGTTAGGCTTATCCACAAGAA
CTTTACCCACTGAGCCATCTGGCTGGCTCCTGGTAATTTTTTTTTTTTTTTACATGTATGAGTG
TTTTGCCTGTATGCATGGTGTCACTTGAAGGCCTCGCTCCCCAAGGAAGCCAGAAAAAGGCATC
TGATCCCTTGGAATTAGAGTTACAGATGTGTGTGAGCCACCACCATGTGGGTGCTAGGAGCTCC
AACCCAGGTCCTCTGGAAGATTAGCCAGTACTCTTTTTTTTTTTTTCTTTTTCTATTTTTCGGA
GCTGGGGACTGAACCCAGGGCCTTGTGCTTGCTAGGCAAGCACTCTACCACTGAGCTAAATCCC
CAACCCCTAGCCAGTACTCTTAACTGCTAAACCACCTCTCCAGGGGCCCAAATCTATAGGATTA
AAATACCCACTCTCTCTTCTCTTCCAATGTTTTGGGGGTTTTGCTTGTTTGTTTGTTTGGTTTT
TAGTGCAAGGTATTAAACTCTCGTCCTTCTAGTTTACCCCTATGCTACAACTCCATCTCCCTGG
TAATTTTTAAAATATTAATAATTAATTACAGTCTTATTCTGTAACTTAAGATGACTTGAACTTG
AATAAATGTTTCTGCCTCGGGCTCTTGAATATCAGAATTACAGGTATGAGCCACGGTACTCAGC
CTGAAATCTTTTTTTTTTTTGAATTGTGTTTACTACACTGGAATT

hide sequence

RefSeq Acc Id:

XM_006228020 ⟹ XP_006228082

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	74,521,648 - 74,529,047 (+)	NCBI
mRatBN7.2	1	65,607,218 - 65,615,395 (+)	NCBI
Rnor_6.0	1	64,182,174 - 64,188,150 (+)	NCBI
Rnor_5.0	1	63,173,549 - 63,180,129 (+)	NCBI

Sequence:

show sequence

TTTCTTTCTCTCCTCAGTGCTGAGGCGAGAACACACTGGGCAAGCAGTCTCCCACTTAGCTGCA
ACATCCACAGCCCCCCTCACCTACTTTAAATCGAATTAAGAGAACACCAGAGGCTATGACTGTT
CTGTCTTGCAACTTTTTCCAAGACAATGAGGCTATGACACAGTTACCCAGGAGCCTCCATCTGA
CTCCTCTGTTCCCTAAACAAGACTCTCACACGGCTTTCTGGTGTTGCTTCATTTCCTCAGAGGG
TAAAAGGCAGGGCCAGCCTTTCCCCAGCTCCACTGAGAGTGCCCGCCATGGTCCTGTTGCTGAT
ACTCCAGCTGTCTACTCTCTGGCCTGTGTGTCATGCTGACTTCACATCACCAGTGCCCCTAGCC
TCATACCCCAAGCCATGGCTGGGGGCTCATCCTGCTGCAATTGTGACTCCTGGAATCAATGTAA
CTTTGATTTGCCGTGCACCCCAACCTGCCTGGGGATTTGGACTCTTCAAAACTGGCCTTGCCAC
CCCTCTGCTCCTCCGGAATGTGTCCATTGGGCTGGCTGAGTTCTTCCTGGAAAAGGTGACTTCG
GTCCAGGAGGGCAGTTATCACTGCCGCTACCGCAAGACAGACTGGGGGCCTGGTGTCTGGTCTC
AGCCCAGTAATGCTCTGGAACTGCTGGTAACAGATCAGCTACCCAGACCATCACTGGTGGCAAT
TCCTGGGCCTGTGGTGGCCCCAGAAACCACTGTAAGCCTGCGCTGTGCAGGCCGCATACCAGGC
ATGAGTTTTGCGCTGTACCGCGCGGATGTGGCAACCCCTCTGCAGTACATCGACTCTGTGCAGC
CCTGGGCTGACTTCCTTCTGAACAGCGCGAATGCACCTGGCACCTACTATTGCTATTACCACAC
CCCCTCTAGCCCCTATGTGCTATCAGAGCGCAGCCAGCCACTGGTCATCAGTTCCGAAGGTTCT
GGCTCCTTGGACTATACCCAGGGAAACCTCGTGCGTTTGGGGCTGGCAGGACTGGTCCTCATCT
GCTTGGGCATCATAGTTACTTTCGATTGGCACAGCAGGCGCTCTGCCTTTGTTCGTCTCCTGCC
CCAGCAAAACTGGGTATAGGCCTGTGCGATGGGAAGAGACTTCCTGGAGACGGACAGAGAAACT
GGGACTCTTGGTGACCAGCCCCTCCGGAACACTCTAAGCTTCCAGACTCCACTGGATTAATTAT
TCTTCACCTCAGTATTAGGCTTGTTGAAGGATTAAAGGAAGTGACCGGCCTGTGGTAAATGATG
TTCAGTTAATGTTAGTGACCTTGTCCTCCCTTGAAAACCTCTATTTCCTTCATGTGTCTTATCT
CCACCCCCCCCCACTCCACCTCTCGTTTCTTTCTTCATGGCTATGTTGGGATCATAGGTTCATT
CTACCACACCCAGCAAAATATATAGTTACGTATTTTAAGGGATGATACGCATGCCTCAGCCTGT
GTGCAAAGGTGAAAAGACAACTTCCAGGAATTGATTTTCTCTGTCCATCCTGTGGGTCCCAGGG
TTTGAACTCAGACTGTTAGTTAGGCTTATCCACAAGAACTTTACCCACTGAGCCATCTGGCTGG
CTCCTGGTAATTTTTTTTTTTTTTTACATGTATGAGTGTTTTGCCTGTATGCATGGTGTCACTT
GAAGGCCTCGCTCCCCAAGGAAGCCAGAAAAAGGCATCTGATCCCTTGGAATTAGAGTTACAGA
TGTGTGTGAGCCACCACCATGTG

hide sequence

RefSeq Acc Id:

XM_039103706 ⟹ XP_038959634

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	74,521,626 - 74,529,047 (+)	NCBI
mRatBN7.2	1	65,607,214 - 65,613,302 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001171902	(Get FASTA)	NCBI Sequence Viewer
	XP_006228082	(Get FASTA)	NCBI Sequence Viewer
	XP_038959634	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL84940	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000071058.2
	ENSRNOP00000079596.1
	ENSRNOP00000087390.1

RefSeq Acc Id:	NP_001171902 ⟸ NM_001184973
- Peptide Label:	precursor
- UniProtKB:	A6KS33 (UniProtKB/TrEMBL), A0A8I5ZN02 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVLLLILQLSTLCELSLPWPVCHADFTSPVPLASYPKPWLGAHPAAIVTPGINVTLICRAPQPA WGFGLFKTGLATPLLLRNVSIGLAEFFLEKVTSVQEGSYHCRYRKTDWGPGVWSQPSNALELLV TDQLPRPSLVAIPGPVVAPETTVSLRCAGRIPGMSFALYRADVATPLQYIDSVQPWADFLLNSA NAPGTYYCYYHTPSSPYVLSERSQPLVISSEGSGSLDYTQGNLVRLGLAGLVLICLGIIVTFDW HSRRSAFVRLLPQQNWV hide sequence

RefSeq Acc Id:	XP_006228082 ⟸ XM_006228020
- Peptide Label:	isoform X1
- UniProtKB:	D3ZCA1 (UniProtKB/TrEMBL), A0A8I5ZN02 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVLLLILQLSTLWPVCHADFTSPVPLASYPKPWLGAHPAAIVTPGINVTLICRAPQPAWGFGLF KTGLATPLLLRNVSIGLAEFFLEKVTSVQEGSYHCRYRKTDWGPGVWSQPSNALELLVTDQLPR PSLVAIPGPVVAPETTVSLRCAGRIPGMSFALYRADVATPLQYIDSVQPWADFLLNSANAPGTY YCYYHTPSSPYVLSERSQPLVISSEGSGSLDYTQGNLVRLGLAGLVLICLGIIVTFDWHSRRSA FVRLLPQQNWV hide sequence

Ensembl Acc Id:

ENSRNOP00000071058 ⟸ ENSRNOT00000090790

RefSeq Acc Id:	XP_038959634 ⟸ XM_039103706
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000087390 ⟸ ENSRNOT00000106643

Ensembl Acc Id:

ENSRNOP00000079596 ⟸ ENSRNOT00000117841

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZCA1-F1-model_v2	AlphaFold	D3ZCA1	1-273	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1559897	AgrOrtholog
BioCyc Gene	G2FUF-61032	BioCyc
Ensembl Genes	ENSRNOG00000055716	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000090790.2	UniProtKB/TrEMBL
	ENSRNOT00000106643.1	UniProtKB/TrEMBL
	ENSRNOT00000117841.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
KEGG Report	rno:292537	UniProtKB/TrEMBL
NCBI Gene	292537	ENTREZGENE
PANTHER	MHC CLASS I NK CELL RECEPTOR	UniProtKB/TrEMBL
	OSTEOCLAST-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR	UniProtKB/TrEMBL
Pfam	Ig_2	UniProtKB/TrEMBL
PhenoGen	Oscar	PhenoGen
RatGTEx	ENSRNOG00000055716	RatGTEx
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A8I5ZN02	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AGG8_RAT	UniProtKB/TrEMBL
	A6KS33	ENTREZGENE, UniProtKB/TrEMBL
	D3ZCA1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-04-04	Oscar	osteoclast associated Ig-like receptor	Oscar	osteoclast associated, immunoglobulin-like receptor	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	Oscar	osteoclast associated, immunoglobulin-like receptor	Oscar	osteoclast associated receptor	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-28	Oscar	osteoclast associated receptor	RGD1559897_predicted	similar to osteoclast-associated receptor mOSCAR-M1 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1559897_predicted	similar to osteoclast-associated receptor mOSCAR-M1 (predicted)	LOC292537	similar to osteoclast-associated receptor mOSCAR-M1	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC292537	similar to osteoclast-associated receptor mOSCAR-M1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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