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ONTOLOGY REPORT - ANNOTATIONS

Term:epidermal growth factor receptor signaling pathway
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Accession:GO:0007173 term browser browse the term
Definition:The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: EGF receptor signaling pathway;   EGF receptor signalling pathway;   EGFR signaling pathway;   ERBB1 signaling pathway;   epidermal growth factor receptor signalling pathway;   receptor tyrosine-protein kinase erbB-1 signaling pathway
 xref: Reactome:R-HSA-177929 "Signaling by EGFR"


show annotations for term's descendants           Sort by:
epidermal growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A acts_upstream_of_or_within ISO (PMID:28790147) RGD PMID:28790147 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B acts_upstream_of_or_within ISO (PMID:28790147) RGD PMID:28790147 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 acts_upstream_of_or_within ISO (PMID:28790147) RGD PMID:28790147 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:95290|MGI:95294 (PMID:18827006)
GO_REF:0000117 		GO_Central
RGD
UniProt		 PMID:18827006 GO_REF:0000033 GO_REF:0000117 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:95290|MGI:95294 (PMID:18827006)
GO_REF:0000117 		GO_Central
RGD
UniProt		 PMID:18827006 GO_REF:0000033 GO_REF:0000117 NCBI chr13:71,223,902...71,319,770
Ensembl chr13:71,224,019...71,389,775 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA 		(PMID:18483258)
GO_REF:0000107 		RGD
Ensembl		 PMID:18483258 GO_REF:0000107 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344 		JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19574994 RGD:2317913 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO
IEA 		(PMID:17215105), (PMID:17655843)
GO_REF:0000107 		RGD
Ensembl		 PMID:17215105 PMID:17655843 GO_REF:0000107 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adra2b adrenoceptor alpha 2B involved_in ISO
IEA 		(PMID:17215105)
GO_REF:0000107 		RGD
Ensembl		 PMID:17215105 GO_REF:0000107 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adra2c adrenoceptor alpha 2C involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18483258), (PMID:20878056) 		Ensembl
RGD		 PMID:18483258 PMID:20878056 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Areg amphiregulin involved_in IDA
ISO
IEA
IBA 		MGI:95294 (PMID:23086930), (PMID:23333074), (PMID:26243875), (PMID:30770250)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000107
(PMID:12743035) 		RGD
UniProt
GO_Central
Ensembl		 PMID:12743035 PMID:23086930 PMID:23333074 PMID:26243875 PMID:30770250 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:1578718 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641 		JBrowse link
G Arf4 ARF GTPase 4 IDA RGD PMID:12446727 RGD:728363 NCBI chr16:1,903,238...1,920,012
Ensembl chr16:1,903,371...1,920,011 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in IDA PMID:9325334 UniProt PMID:9325334 RGD:8554610 NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member involved_in ISO
IEA
IBA 		(PMID:18722344)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:18722344 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:213,209,907...213,323,305
Ensembl chr 2:213,209,893...213,323,302 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase involved_in ISO (PMID:18567582) RGD PMID:18567582 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931 		JBrowse link
G Btc betacellulin involved_in IDA
ISO
IEA
IBA 		MGI:95294 (PMID:18656477), (PMID:8456283)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000107
(PMID:8144591) 		RGD
UniProt
GO_Central
Ensembl		 PMID:8144591 PMID:8456283 PMID:18656477 PMID:11564606 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:2324625 NCBI chr14:16,992,668...17,031,178
Ensembl chr14:16,992,193...17,033,078 		JBrowse link
G Cripto cripto, EGF-CFC family member NOT|acts_upstream_of_or_within ISO (PMID:8006041) RGD PMID:8006041 NCBI chr 8:119,803,182...119,808,714
Ensembl chr 8:119,803,220...119,808,948 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
IEA 		(PMID:18356165)
GO_REF:0000107 		RGD
Ensembl		 PMID:18356165 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Dbx2 developing brain homeobox 2 acts_upstream_of_or_within ISO (PMID:37605090) RGD PMID:37605090 NCBI chr 7:128,651,603...128,681,886
Ensembl chr 7:128,651,635...128,681,973 		JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO UniProtKB:P01133 (PMID:22732145) RGD PMID:22732145 NCBI chr14:1,203,380...1,217,536
Ensembl chr14:1,203,565...1,218,024 		JBrowse link
G Efemp1 EGF-like fibulin extracellular matrix protein 1 involved_in ISO
IEA
ISS 		(PMID:19804359)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:19804359 GO_REF:0000024 GO_REF:0000107 NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808 		JBrowse link
G Egf epidermal growth factor involved_in
acts_upstream_of_or_within 		IDA
ISO
IEA
IBA 		(PMID:12761849), (PMID:6248866), (PMID:7752576), (PMID:9529375)
MGI:95294 (PMID:15695332), (PMID:6315706), (PMID:7641815)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000033
(PMID:15611079), (PMID:18567582), (PMID:20353436), (PMID:22732145), (PMID:31915155) 		RGD
UniProt
Ensembl
GO_Central		 PMID:6248866 PMID:6315706 PMID:7641815 PMID:7752576 PMID:9529375 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:1626483 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egfr epidermal growth factor receptor acts_upstream_of_or_within
involved_in 		IDA
ISO
IBA
IMP 		MGI:95290 (PMID:14712229), (PMID:15695332), (PMID:17686994), (PMID:7641815)
MGI:107508|MGI:3763534 (PMID:12399441), (PMID:12761849), (PMID:23333074), (PMID:23899604), (PMID:28783046), (PMID:30770250), (PMID:6248866), (PMID:7678348), (PMID:7752576), (PMID:8456283), (PMID:8702723), (PMID:9556621)
(PMID:7736574), (PMID:9890893)
(PMID:12435727), (PMID:12828935), (PMID:17655843), (PMID:18483258), (PMID:20878056), (PMID:24854121), (PMID:9890893)
GO_REF:0000033
PMID:20639532 		RGD
GO_Central		 PMID:6248866 PMID:7641815 PMID:7678348 PMID:7736574 PMID:7752576 More... GO_REF:0000033, RGD:70386, RGD:8553583, RGD:1581908 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Epgn epithelial mitogen involved_in ISO
IEA
ISS 		(PMID:15611079)
MGI:95294 (PMID:11278323), (PMID:23899604), (PMID:24891618)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000024 		RGD
UniProt
Ensembl
HGNC-UCL		 PMID:11278323 PMID:15611079 PMID:23899604 PMID:24891618 GO_REF:0000024 GO_REF:0000107 GO_REF:0000117 NCBI chr14:17,360,968...17,369,000
Ensembl chr14:17,360,968...17,369,000 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 involved_in IMP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:14711829 GO_REF:0000033, RGD:2289958 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:1,579,816...1,601,120 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in IEA
IBA 		GO_REF:0000108
GO_REF:0000033 		GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772 		JBrowse link
G Ereg epiregulin involved_in
acts_upstream_of_or_within 		ISS
ISO
IEA
IBA
IDA 		GO_REF:0000024
(PMID:7706296)
MGI:95294 (PMID:28783046)
(PMID:9556621)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000107
PMID:9990076
(PMID:28783046), (PMID:9556621) 		UniProt
RGD
GO_Central
Ensembl		 PMID:7706296 PMID:9556621 PMID:28783046 PMID:9990076 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:632743 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 acts_upstream_of_or_within ISO MGI:3769404|MGI:5575860 (PMID:19683494), (PMID:22136853), (PMID:22975324), (PMID:24550287) RGD PMID:19683494 PMID:22136853 PMID:22975324 PMID:24550287 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432 		JBrowse link
G Fam83a family with sequence similarity 83, member A involved_in ISO
IEA
IBA 		(PMID:22886303)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:22886303 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:91,412,366...91,436,819
Ensembl chr 7:91,412,366...91,436,910 		JBrowse link
G Gab1 GRB2-associated binding protein 1 acts_upstream_of_or_within
involved_in 		ISO MGI:1926435 (PMID:10779359)
MGI:3759868 (PMID:17881575) 		RGD PMID:10779359 PMID:17881575 NCBI chr19:44,035,693...44,143,617
Ensembl chr19:44,035,063...44,143,617 		JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 involved_in ISO
IEA
IBA 		(PMID:19509291)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:19509291 GO_REF:0000033 GO_REF:0000107 NCBI chr18:12,695,082...12,860,219
Ensembl chr18:12,695,082...12,860,219 		JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO
IEA 		(PMID:8253073)
GO_REF:0000107
MGI:108088 (PMID:17881575) 		RGD
Ensembl		 PMID:8253073 PMID:17881575 GO_REF:0000107 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor acts_upstream_of_or_within
involved_in 		TAS
ISO
IBA
IEA
IMP 		(PMID:12621152)
(PMID:8702723)
GO_REF:0000033
GO_REF:0000117
GO_REF:0000107
(PMID:17655843), (PMID:8702723) 		RGD
GO_Central
UniProt
Ensembl		 PMID:8702723 PMID:12621152 PMID:17655843 PMID:11956950 PMID:15486316 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:728846, RGD:1581908 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO
IEA 		(PMID:18356165)
GO_REF:0000107 		RGD
Ensembl		 PMID:18356165 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:17,222,856...17,244,370 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 involved_in ISO
IEA 		(PMID:17563371), (PMID:18567582)
GO_REF:0000107 		RGD
Ensembl		 PMID:17563371 PMID:18567582 GO_REF:0000107 NCBI chr 1:144,088,788...144,178,989
Ensembl chr 1:144,088,793...144,179,043 		JBrowse link
G Kif16b kinesin family member 16B involved_in ISO (PMID:15882625) RGD PMID:15882625 NCBI chr 3:150,428,233...150,707,755
Ensembl chr 3:150,366,838...150,707,770 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO
IEA 		(PMID:24854121)
GO_REF:0000107 		RGD
Ensembl		 PMID:24854121 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:24854121) RGD PMID:24854121 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in IEA
ISO 		GO_REF:0000107
MGI:1856702|MGI:5911053 (PMID:22987720), (PMID:26522847) 		Ensembl
RGD		 PMID:22987720 PMID:26522847 GO_REF:0000107 NCBI chr 5:62,678,197...62,697,360
Ensembl chr 5:62,678,367...62,697,343 		JBrowse link
G Nrg2 neuregulin 2 IDA RGD PMID:9348101 RGD:1304015 NCBI chr18:27,890,578...28,072,538
Ensembl chr18:27,890,578...28,072,538 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO
IEA 		(PMID:22454520)
GO_REF:0000107 		RGD
Ensembl		 PMID:22454520 GO_REF:0000107 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181 		JBrowse link
G Pigr polymeric immunoglobulin receptor involved_in IEA
ISO 		GO_REF:0000107
(PMID:22022593) 		Ensembl
RGD		 PMID:22022593 GO_REF:0000107 NCBI chr13:44,851,001...44,879,143
Ensembl chr13:44,851,182...44,879,141 		JBrowse link
G Plce1 phospholipase C, epsilon 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:29058690)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:29058690 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828 		JBrowse link
G Plcg1 phospholipase C, gamma 1 involved_in ISO
IEA
IDA 		(PMID:22454520)
GO_REF:0000107
PMID:7531435 		RGD
Ensembl		 PMID:22454520 PMID:7531435 GO_REF:0000107, RGD:39458025 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:27378169) 		Ensembl
RGD		 PMID:27378169 GO_REF:0000107 NCBI chr 7:126,518,587...126,614,581
Ensembl chr 7:126,518,587...126,614,581 		JBrowse link
G Ptk2 protein tyrosine kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:16945503 GO_REF:0000033, RGD:1642613 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in
acts_upstream_of_or_within 		ISO MGI:95294 (PMID:10700187)
MGI:87859|MGI:87860|MGI:95290|MGI:95294 (PMID:18827006) 		RGD PMID:10700187 PMID:18827006 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577 		JBrowse link
G Shc1 SHC adaptor protein 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:23846654) 		GO_Central
RGD		 PMID:23846654 GO_REF:0000033 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 acts_upstream_of_or_within ISO (PMID:26728129) RGD PMID:26728129 NCBI chr13:99,529,664...99,584,442
Ensembl chr13:99,529,790...99,544,213 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000002
(PMID:15695332) 		InterPro
RGD		 PMID:15695332 GO_REF:0000002 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:8663461)
GO_REF:0000107
MGI:2155441 (PMID:9030684) 		RGD
Ensembl		 PMID:8663461 PMID:9030684 GO_REF:0000107 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:21512138)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:21512138 GO_REF:0000024 GO_REF:0000107 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250 		JBrowse link
G Spg21 SPG21 abhydrolase domain containing, maspardin acts_upstream_of_or_within ISO (PMID:26978163) RGD PMID:26978163 NCBI chr 8:74,876,136...74,903,676
Ensembl chr 8:74,876,136...74,903,676 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:15856020 GO_REF:0000033, RGD:1581134 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Tgfa transforming growth factor alpha involved_in
acts_upstream_of_or_within 		TAS
ISO
IBA 		(PMID:17881575), (PMID:7752576)
GO_REF:0000033
(PMID:6315706) 		RGD
GO_Central		 PMID:6315706 PMID:7752576 PMID:17881575 PMID:2103501 GO_REF:0000033, RGD:1578565 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339 		JBrowse link
G Vil1 villin 1 involved_in ISO
IEA 		(PMID:17229814)
GO_REF:0000107 		RGD
Ensembl		 PMID:17229814 GO_REF:0000107 NCBI chr 9:83,440,248...83,467,963
Ensembl chr 9:83,440,248...83,467,961 		JBrowse link
epidermal growth factor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab7a RAB7A, member RAS oncogene family involved_in ISO
IEA 		(PMID:18272684)
GO_REF:0000107
(PMID:16282324) 		RGD
Ensembl		 PMID:16282324 PMID:18272684 GO_REF:0000107 NCBI chr 4:122,019,281...122,068,067
Ensembl chr 4:121,983,938...122,064,185 		JBrowse link
G Snx5 sorting nexin 5 IDA RGD PMID:16487940 RGD:13508623 NCBI chr 3:152,075,258...152,094,508
Ensembl chr 3:152,075,258...152,094,877 		JBrowse link
ERBB2-EGFR signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:8702723)
GO_REF:0000107 		RGD
Ensembl		 PMID:8702723 GO_REF:0000107 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641 		JBrowse link
G Btc betacellulin involved_in ISO (PMID:21897861) RGD PMID:21897861 NCBI chr14:16,992,668...17,031,178
Ensembl chr14:16,992,193...17,033,078 		JBrowse link
G Egf epidermal growth factor involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:11336639)
(PMID:22822073)
GO_REF:0000107 		RGD
Ensembl		 PMID:11336639 PMID:22822073 GO_REF:0000107 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egfr epidermal growth factor receptor involved_in
acts_upstream_of_or_within 		ISO (PMID:11336639)
MGI:1856402 (PMID:18701712), (PMID:21897861), (PMID:21946538), (PMID:8702723), (PMID:9556621) 		RGD PMID:8702723 PMID:9556621 PMID:11336639 PMID:18701712 PMID:21897861 More... NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:8702723)
MGI:95294 (PMID:16357442), (PMID:18701712), (PMID:21897861), (PMID:8702723), (PMID:9556621)
GO_REF:0000107 		RGD
Ensembl		 PMID:8702723 PMID:9556621 PMID:16357442 PMID:18701712 PMID:21897861 GO_REF:0000107 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Ereg epiregulin involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:9556621)
(PMID:28783046)
GO_REF:0000107 		RGD
Ensembl		 PMID:9556621 PMID:28783046 GO_REF:0000107 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor involved_in IEA
ISO 		GO_REF:0000107
MGI:2665039 (PMID:21946538) 		Ensembl
RGD		 PMID:21946538 GO_REF:0000107 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220 		JBrowse link
G Tgfa transforming growth factor alpha involved_in
acts_upstream_of_or_within 		ISO (PMID:8702723) RGD PMID:8702723 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339 		JBrowse link
negative regulation of epidermal growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene involved_in ISO
IEA
IBA 		(PMID:25178484)
(PMID:23457600)
MGI:2180578|MGI:95294 (PMID:11823423), (PMID:12754251)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:11823423 PMID:12754251 PMID:23457600 PMID:25178484 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:53,384,656...53,468,067 		JBrowse link
G Cblb Cbl proto-oncogene B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:62,058,829...62,225,904
Ensembl chr11:62,061,653...62,225,778 		JBrowse link
G Cblc Cbl proto-oncogene C involved_in ISO
IEA
IBA 		(PMID:10362357)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:10362357 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:88,567,932...88,584,709 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in IDA PMID:11812785 BHF-UCL PMID:11812785 RGD:632628 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:39,312,745...39,483,730 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO (PMID:28759036) RGD PMID:28759036 NCBI chr10:87,420,213...87,434,202
Ensembl chr10:87,419,494...87,434,063 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:11823423), (PMID:23457600) RGD PMID:11823423 PMID:23457600 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 involved_in IMP
ISO
IEA
IBA 		(PMID:19710174)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:19710174 PMID:19204184 GO_REF:0000033 GO_REF:0000107, RGD:9685562 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432 		JBrowse link
G Itga1 integrin subunit alpha 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:15592458)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:15592458 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:48,379,181...48,545,336
Ensembl chr 2:48,386,249...48,545,284 		JBrowse link
G Mir133a1 microRNA 133a-1 involved_in ISO (PMID:23069713) RGD PMID:23069713 NCBI chr18:2,157,872...2,157,958 JBrowse link
G Mir3582 microRNA 3582 involved_in ISO (PMID:23069713) RGD PMID:23069713 NCBI chr18:2,157,853...2,157,970
Ensembl chr18:2,157,853...2,157,970 		JBrowse link
G Mvp major vault protein involved_in ISO
IEA 		(PMID:16441665)
GO_REF:0000107 		RGD
Ensembl		 PMID:16441665 GO_REF:0000107 NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:191,025,268...191,052,873 		JBrowse link
G Nppa natriuretic peptide A involved_in ISO (PMID:20353436) RGD PMID:20353436 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nup62 nucleoporin 62 involved_in ISO (PMID:11489947) RGD PMID:11489947 NCBI chr 1:104,435,532...104,451,392
Ensembl chr 1:104,432,093...104,452,710 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of ISO (PMID:20208556) RGD PMID:20208556 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:94,499,928...94,525,116 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:15592458) 		UniProt
Ensembl
RGD		 PMID:15592458 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:63,498,890...63,564,481 		JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F IMP RGD PMID:8557682 RGD:1642757 NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO
IEA 		(PMID:19836242)
GO_REF:0000107 		RGD
Ensembl		 PMID:19836242 GO_REF:0000107 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:96,861,785...97,017,656 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO
IEA 		(PMID:23418353)
GO_REF:0000107 		RGD
Ensembl		 PMID:23418353 GO_REF:0000107 NCBI chr 2:186,950,959...187,018,673
Ensembl chr 2:186,950,760...187,019,561 		JBrowse link
G Rnf126 ring finger protein 126 involved_in ISO (PMID:23418353) RGD PMID:23418353 NCBI chr 7:10,590,013...10,597,585
Ensembl chr 7:10,590,039...10,598,132 		JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in ISO
IEA 		(PMID:24854121)
GO_REF:0000107 		RGD
Ensembl		 PMID:24854121 GO_REF:0000107 NCBI chr 5:104,699,270...104,874,724
Ensembl chr 5:104,698,929...105,159,896 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:122,484,995...122,490,008
Ensembl chr 2:122,484,355...122,492,956 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:89,106,809...89,111,926
Ensembl chr15:89,103,731...89,115,074 		JBrowse link
G Spry3 sprouty RTK signaling antagonist 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:21,777,090...21,786,280
Ensembl chr12:21,776,005...21,786,804 		JBrowse link
G Spry3-ps1 sprouty RTK signaling antagonist 3, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:36,986,740...36,987,342
Ensembl chr 1:36,986,740...36,987,805 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:30,687,633...30,702,546
Ensembl chr18:30,687,039...30,704,173 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:3038304 (PMID:16449191) RGD PMID:16449191 NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219 		JBrowse link
G Tsg101 tumor susceptibility 101 involved_in ISO
IEA 		(PMID:16554368)
GO_REF:0000107 		RGD
Ensembl		 PMID:16554368 GO_REF:0000107 NCBI chr 1:106,549,035...106,578,859
Ensembl chr 1:106,535,021...106,578,775 		JBrowse link
G Zfyve28 zinc finger FYVE-type containing 28 involved_in ISO
IEA
IBA 		(PMID:19460345)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:19460345 GO_REF:0000033 GO_REF:0000107 NCBI chr14:80,692,997...80,778,606
Ensembl chr14:80,692,819...80,778,586 		JBrowse link
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp6 charged multivesicular body protein 6 involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr10:105,690,400...105,696,070
Ensembl chr10:105,690,398...105,696,333 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 involved_in IDA
ISO
ISS 		PMID:17599051
(PMID:16648858)
(PMID:18046415)
GO_REF:0000024 		RGD
UniProt		 PMID:16648858 PMID:18046415 PMID:17599051 GO_REF:0000024, RGD:8553726 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432 		JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A involved_in ISO (PMID:25744720) RGD PMID:25744720 NCBI chr 4:169,634,896...169,653,627
Ensembl chr 4:169,634,748...169,653,625 		JBrowse link
G Socs4 suppressor of cytokine signaling 4 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr15:23,003,130...23,017,615
Ensembl chr15:23,002,883...23,022,499 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) RGD PMID:15590694 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883 		JBrowse link
G Tsg101 tumor susceptibility 101 involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr 1:106,549,035...106,578,859
Ensembl chr 1:106,535,021...106,578,775 		JBrowse link
G Vps25 vacuolar protein sorting 25 homolog involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr10:86,696,330...86,701,871
Ensembl chr10:86,696,157...86,701,871 		JBrowse link
G Zfyve28 zinc finger FYVE-type containing 28 involved_in ISO (PMID:19460345) RGD PMID:19460345 NCBI chr14:80,692,997...80,778,606
Ensembl chr14:80,692,819...80,778,586 		JBrowse link
G Zgpat zinc finger CCCH-type and G-patch domain containing involved_in ISS
ISO 		GO_REF:0000024
(PMID:19644445) 		UniProt
RGD		 PMID:19644445 GO_REF:0000024 NCBI chr 3:188,851,376...188,867,914
Ensembl chr 3:188,851,566...188,868,495 		JBrowse link
positive regulation of epidermal growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in
acts_upstream_of 		IEA
ISO
IMP 		GO_REF:0000107
(PMID:12743035), (PMID:17655843)
(PMID:18625725) 		Ensembl
RGD		 PMID:12743035 PMID:17655843 PMID:18625725 PMID:25232008 GO_REF:0000107, RGD:13703036 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO
IEA 		(PMID:17655843)
GO_REF:0000107 		RGD
Ensembl		 PMID:17655843 GO_REF:0000107 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Afap1l2 actin filament associated protein 1-like 2 involved_in ISO
IBA
IEA 		(PMID:17412687)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:17412687 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:265,969,368...266,065,951
Ensembl chr 1:265,969,368...266,065,943 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member involved_in ISO
IEA 		(PMID:25666625)
GO_REF:0000107 		RGD
Ensembl		 PMID:25666625 GO_REF:0000107 NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:58,435,908...58,456,677 		JBrowse link
G Agt angiotensinogen involved_in ISO
IEA 		(PMID:15652490)
GO_REF:0000107 		RGD
Ensembl		 PMID:15652490 GO_REF:0000107 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 involved_in ISO (PMID:30241478) RGD PMID:30241478 NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) RGD PMID:23389627 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646 		JBrowse link
G Ccdc88a coiled-coil and HOOK domain protein 88A involved_in ISO (PMID:20462955) RGD PMID:20462955 NCBI chr14:107,304,654...107,456,104
Ensembl chr14:107,305,199...107,453,285 		JBrowse link
G Cnot9 CCR4-NOT transcription complex subunit 9 involved_in ISO
IEA 		(PMID:20878056)
GO_REF:0000107 		RGD
Ensembl		 PMID:20878056 GO_REF:0000107 NCBI chr 9:83,533,369...83,558,207
Ensembl chr 9:83,533,369...83,558,197 		JBrowse link
G Dgkd diacylglycerol kinase, delta involved_in ISO (PMID:17021016) RGD PMID:17021016 NCBI chr 9:95,964,507...96,055,160
Ensembl chr 9:95,964,148...96,055,160 		JBrowse link
G Esr1 estrogen receptor 1 involved_in IMP
IEA 		GO_REF:0000117 UniProt
RGD		 PMID:17928626 GO_REF:0000117, RGD:5128669 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 involved_in IMP
IEA 		GO_REF:0000117 UniProt
RGD		 PMID:17928626 GO_REF:0000117, RGD:5128669 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Fam83b family with sequence similarity 83, member B involved_in ISO
IEA 		(PMID:22886302), (PMID:23676467), (PMID:23912460)
GO_REF:0000107 		RGD
Ensembl		 PMID:22886302 PMID:23676467 PMID:23912460 GO_REF:0000107 NCBI chr 8:86,167,778...86,244,222
Ensembl chr 8:86,167,778...86,244,222 		JBrowse link
G Faslg Fas ligand IMP RGD PMID:18471522 RGD:2315731 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 2:172,447,738...172,609,591
Ensembl chr 2:172,447,738...172,609,591 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IMP
ISO
IEA 		(PMID:15705806)
GO_REF:0000117
(PMID:21673097) 		RGD
UniProt		 PMID:15705806 PMID:21673097 PMID:20445128 GO_REF:0000117, RGD:4892084 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144 		JBrowse link
G Hap1 huntingtin-associated protein 1 involved_in IMP PMID:12890790 UniProt PMID:12890790 RGD:10047165 NCBI chr10:85,778,267...85,786,553
Ensembl chr10:85,778,267...85,786,503 		JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in ISO
IBA 		(PMID:14732715)
GO_REF:0000033 		RGD
GO_Central		 PMID:14732715 GO_REF:0000033 NCBI chr12:26,769,868...26,904,367
Ensembl chr12:26,769,961...26,904,296 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO
IBA
IEA 		(PMID:14732715)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:14732715 GO_REF:0000033 GO_REF:0000107 NCBI chr12:38,251,085...38,279,756
Ensembl chr12:38,251,086...38,279,654 		JBrowse link
G Mir29a microRNA 29a involved_in ISO (PMID:25058496) RGD PMID:25058496 NCBI chr 4:60,617,955...60,618,042 JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in ISO
IEA 		(PMID:22984561)
GO_REF:0000107 		RGD
Ensembl		 PMID:22984561 GO_REF:0000107 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Neu3 neuraminidase 3 involved_in ISO (PMID:17334392) RGD PMID:17334392 NCBI chr 1:163,549,834...163,560,997
Ensembl chr 1:163,549,738...163,561,049 		JBrowse link
G Pde6g phosphodiesterase 6G involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000117
(PMID:11502744) 		GO_Central
UniProt
RGD		 PMID:11502744 GO_REF:0000033 GO_REF:0000117 NCBI chr10:106,219,849...106,224,496
Ensembl chr10:106,219,849...106,224,496 		JBrowse link
G Pde6h phosphodiesterase 6H involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000117
(PMID:11502744) 		GO_Central
UniProt
RGD		 PMID:11502744 GO_REF:0000033 GO_REF:0000117 NCBI chr 4:171,588,896...171,604,142
Ensembl chr 4:171,588,974...171,604,249 		JBrowse link
G Plau plasminogen activator, urokinase involved_in ISO
IEA 		(PMID:30241478)
GO_REF:0000107 		RGD
Ensembl		 PMID:30241478 GO_REF:0000107 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO
IEA 		(PMID:22984561)
GO_REF:0000107 		RGD
Ensembl		 PMID:22984561 GO_REF:0000107 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130 		JBrowse link
G Rala RAS like proto-oncogene A involved_in ISO
IEA 		UniProtKB:P11234 (PMID:34096503)
GO_REF:0000107 		RGD
Ensembl		 PMID:34096503 GO_REF:0000107 NCBI chr17:51,787,682...51,840,738
Ensembl chr17:51,787,699...51,840,733 		JBrowse link
G Ralb RAS like proto-oncogene B involved_in ISO
IEA 		UniProtKB:P11233 (PMID:34096503)
GO_REF:0000107 		RGD
Ensembl		 PMID:34096503 GO_REF:0000107 NCBI chr13:33,140,834...33,176,997
Ensembl chr13:33,140,835...33,176,998 		JBrowse link
G Shkbp1 Sh3kbp1 binding protein 1 involved_in ISS
IBA
IEA
ISO 		GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:21830225) 		UniProt
GO_Central
Ensembl
RGD		 PMID:21830225 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:91,764,426...91,777,959
Ensembl chr 1:91,764,426...91,778,158 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IEP RGD PMID:8577724 RGD:1581110 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15962011) 		Ensembl
RGD		 PMID:15962011 GO_REF:0000107 NCBI chr15:89,106,809...89,111,926
Ensembl chr15:89,103,731...89,115,074 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of ISS
ISO 		GO_REF:0000024
(PMID:18625725) 		UniProt
RGD		 PMID:18625725 GO_REF:0000024 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
regulation of epidermal growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh13 cadherin 13 involved_in ISO
IEA 		(PMID:17573778)
GO_REF:0000107 		RGD
Ensembl		 PMID:17573778 GO_REF:0000107 NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IMP
ISO
ISS 		PMID:15467833
(PMID:15467833)
GO_REF:0000024 		RGD
UniProt		 PMID:15467833 PMID:15467833 GO_REF:0000024, RGD:11059592 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798 		JBrowse link
G Fer FER tyrosine kinase involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:21518868) 		UniProt
Ensembl
RGD		 PMID:21518868 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:110,967,390...111,274,315 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:24012640) RGD PMID:24012640 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mvb12a multivesicular body subunit 12A involved_in ISO
IBA
IEA 		(PMID:20654576)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:20654576 GO_REF:0000033 GO_REF:0000107 NCBI chr16:18,286,231...18,291,096
Ensembl chr16:18,286,231...18,292,583 		JBrowse link
G Mvb12b multivesicular body subunit 12B involved_in ISO
IBA 		(PMID:20654576)
GO_REF:0000033 		RGD
GO_Central		 PMID:20654576 GO_REF:0000033 NCBI chr 3:37,431,636...37,590,276
Ensembl chr 3:37,431,636...37,615,407 		JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 involved_in ISO
IEA
IBA 		(PMID:27134172)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:27134172 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:14,913,071...14,985,084
Ensembl chr 4:14,913,218...14,985,284 		JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 involved_in ISS
IEA
IBA
ISO 		GO_REF:0000024
GO_REF:0000104
GO_REF:0000033
(PMID:18832597) 		UniProt
GO_Central
RGD		 PMID:18832597 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr10:15,911,282...15,924,214
Ensembl chr10:15,911,308...15,924,214 		JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 involved_in IBA
IEA 		GO_REF:0000033
GO_REF:0000104 		GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 NCBI chr10:102,331,991...102,359,117
Ensembl chr10:102,331,991...102,359,117 		JBrowse link
G Wdr54 WD repeat domain 54 involved_in ISO
IEA 		(PMID:30458214)
GO_REF:0000107 		RGD
Ensembl		 PMID:30458214 GO_REF:0000107 NCBI chr 4:117,212,677...117,236,456
Ensembl chr 4:117,212,677...117,219,270 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19688
    cellular process 18845
      signal transduction 7248
        cell surface receptor signaling pathway 2949
          enzyme-linked receptor protein signaling pathway 1106
            cell surface receptor protein tyrosine kinase signaling pathway 693
              ERBB signaling pathway 149
                epidermal growth factor receptor signaling pathway 131
                  ERBB2-EGFR signaling pathway 8
                  ERBB4-EGFR signaling pathway 0
                  epidermal growth factor receptor signaling pathway involved in heart process + 0
                  epidermal growth factor receptor signaling pathway involved in lung development 0
                  epidermal growth factor signaling pathway involved in forebrain neuron fate commitment 0
                  negative regulation of epidermal growth factor receptor signaling pathway + 37
                  positive regulation of epidermal growth factor receptor signaling pathway + 32
                  regulation of epidermal growth factor receptor signaling pathway + 78
Path 2
Term Annotations click to browse term
  biological_process 19688
    biological regulation 13561
      regulation of biological process 13114
        signaling 7810
          signal transduction 7248
            cell surface receptor signaling pathway 2949
              enzyme-linked receptor protein signaling pathway 1106
                cell surface receptor protein tyrosine kinase signaling pathway 693
                  ERBB signaling pathway 149
                    epidermal growth factor receptor signaling pathway 131
                      ERBB2-EGFR signaling pathway 8
                      ERBB4-EGFR signaling pathway 0
                      epidermal growth factor receptor signaling pathway involved in heart process + 0
                      epidermal growth factor receptor signaling pathway involved in lung development 0
                      epidermal growth factor signaling pathway involved in forebrain neuron fate commitment 0
                      negative regulation of epidermal growth factor receptor signaling pathway + 37
                      positive regulation of epidermal growth factor receptor signaling pathway + 32
                      regulation of epidermal growth factor receptor signaling pathway + 78
paths to the root