The series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.
ERBB2-ERBB3 signaling pathway
ERBB2-ERBB4 signaling pathway
ERBB4-EGFR signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway +
positive regulation of epidermal growth factor receptor signaling pathway +
regulation of epidermal growth factor receptor signaling pathway +