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Gene: Pde6h (phosphodiesterase 6H) Rattus norvegicus
Symbol: Pde6h
Name: phosphodiesterase 6H
RGD ID: 70933
Description: Predicted to have 3',5'-cyclic-GMP phosphodiesterase activity and cGMP binding activity. Predicted to be involved in activation of MAPK activity; positive regulation of G protein-coupled receptor signaling pathway; and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to localize to photoreceptor outer segment membrane. Orthologous to human PDE6H (phosphodiesterase 6H); PARTICIPATES IN visual phototransduction pathway; purine metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GMP-PDE gamma; Pde6g; phosphodiesterase 6G, cGMP-specific, rod, gamma; phosphodiesterase 6H, cGMP-specific, cone, gamma; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Homo sapiens (human) : PDE6H (phosphodiesterase 6H)  HGNC  Alliance
Mus musculus (house mouse) : Pde6h (phosphodiesterase 6H, cGMP-specific, cone, gamma)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde6h (phosphodiesterase 6H)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE6H (phosphodiesterase 6H)
Canis lupus familiaris (dog) : PDE6H (phosphodiesterase 6H)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde6h (phosphodiesterase 6H)
Sus scrofa (pig) : PDE6H (phosphodiesterase 6H)
Chlorocebus sabaeus (African green monkey) : PDE6H (phosphodiesterase 6H)
Heterocephalus glaber (naked mole-rat) : Pde6h (phosphodiesterase 6H)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04170,947,723 - 170,963,046 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4170,958,196 - 170,963,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04235,204,371 - 235,219,664 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44174,009,860 - 174,014,405 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14174,254,983 - 174,259,529 (+)NCBI
Celera4158,449,142 - 158,453,876 (+)NCBICelera
Cytogenetic Map4q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pde6h
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70933
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.