CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 2,4-diaminotoluene
Accession: CHEBI:34237
browse the term
Definition: An aminotoluene that is para-toluidine with an additional amino group at position 2.
Synonyms: exact_synonym: 4-methylbenzene-1,3-diamine
related_synonym: Formula=C7H10N2; InChI=1S/C7H10N2/c1-5-2-3-6(8)4-7(5)9/h2-4H,8-9H2,1H3; InChIKey=VOZKAJLKRJDJLL-UHFFFAOYSA-N; SMILES=Cc1ccc(N)cc1N
xref: CAS:95-80-7; KEGG:C14401
xref_mesh: MESH:C010914
xref: Reaxys:2205839
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Aadat
aminoadipate aminotransferase
increases expression
EXP
2,4-diaminotoluene results in increased expression of AADAT mRNA
CTD
PMID:22016648
NCBI chr 8:60,958,877...60,998,711
Ensembl chr 8:60,958,966...60,998,711
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Abcb1b
ATP-binding cassette, sub-family B member 1B
increases expression
ISO
2,4-diaminotoluene results in increased expression of ABCB1B mRNA
CTD
PMID:17070881
NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
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Acmsd
amino carboxymuconate semialdehyde decarboxylase
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of ACMSD mRNA
CTD
PMID:17070881
NCBI chr 1:127,657,149...127,695,723
Ensembl chr 1:127,657,150...127,695,715
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Acsl3
acyl-CoA synthetase long-chain family member 3
increases expression
ISO
2,4-diaminotoluene results in increased expression of ACSL3 mRNA
CTD
PMID:17070881
NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
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Adam8
a disintegrin and metallopeptidase domain 8
increases expression
EXP
2,4-diaminotoluene results in increased expression of ADAM8 mRNA
CTD
PMID:20713471
NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475
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Adamts1
ADAM metallopeptidase with thrombospondin type 1 motif 1
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of ADAMTS1 mRNA
CTD
PMID:20713471
NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001
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Adamts4
ADAM metallopeptidase with thrombospondin type 1 motif 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of ADAMTS4 mRNA
CTD
PMID:20713471
NCBI chr 1:171,077,698...171,089,836
Ensembl chr 1:171,077,990...171,088,206
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Adgrl2
adhesion G protein-coupled receptor L2
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of ADGRL2 mRNA
CTD
PMID:20713471
NCBI chr 3:148,521,491...149,150,832
Ensembl chr 3:148,521,219...148,696,191
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Aen
apoptosis enhancing nuclease
increases expression
ISO
2,4-diaminotoluene results in increased expression of AEN mRNA
CTD
PMID:17070881
NCBI chr 7:78,545,675...78,560,957
Ensembl chr 7:78,545,602...78,560,957
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Afp
alpha fetoprotein
increases expression
EXP
2,4-diaminotoluene results in increased expression of AFP mRNA
CTD
PMID:20713471
NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
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Ahr
aryl-hydrocarbon receptor
affects binding multiple interactions
ISO
2,4-diaminotoluene binds to AHR protein 2,4-diaminotoluene inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]
CTD
PMID:8685904
NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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Alcam
activated leukocyte cell adhesion molecule
increases expression
EXP
2,4-diaminotoluene results in increased expression of ALCAM mRNA
CTD
PMID:20713471
NCBI chr16:52,069,359...52,273,444
Ensembl chr16:52,069,359...52,274,437
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Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
increases expression
ISO
2,4-diaminotoluene results in increased expression of ALDH1A1 mRNA
CTD
PMID:17070881
NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
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Aldh3a1
aldehyde dehydrogenase family 3, subfamily A1
increases expression
EXP
2,4-diaminotoluene results in increased expression of ALDH3A1 mRNA
CTD
PMID:20713471
NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247
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Ank
progressive ankylosis
increases expression
EXP
2,4-diaminotoluene results in increased expression of ANK mRNA
CTD
PMID:20713471
NCBI chr15:27,466,763...27,594,995
Ensembl chr15:27,466,763...27,594,995
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Ankrd37
ankyrin repeat domain 37
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of ANKRD37 mRNA
CTD
PMID:20713471
NCBI chr 8:46,449,945...46,452,904
Ensembl chr 8:46,449,939...46,458,744
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Anln
anillin, actin binding protein
increases expression
EXP
2,4-diaminotoluene results in increased expression of ANLN mRNA
CTD
PMID:20713471
NCBI chr 9:22,243,305...22,302,132
Ensembl chr 9:22,243,308...22,300,484
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Anxa8
annexin A8
increases expression
EXP
2,4-diaminotoluene results in increased expression of ANXA8 mRNA
CTD
PMID:20713471
NCBI chr14:33,807,936...33,822,528
Ensembl chr14:33,807,938...33,822,528
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Apcdd1
adenomatosis polyposis coli down-regulated 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of APCDD1 mRNA
CTD
PMID:20713471
NCBI chr18:63,055,398...63,086,886
Ensembl chr18:63,055,302...63,094,250
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Apoa2
apolipoprotein A-II
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of APOA2 mRNA
CTD
PMID:17070881
NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948
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Apoa4
apolipoprotein A-IV
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of APOA4 mRNA
CTD
PMID:17070881
NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
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Apoc3
apolipoprotein C-III
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of APOC3 mRNA
CTD
PMID:17070881
NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934
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Arhgap11a
Rho GTPase activating protein 11A
increases expression
EXP
2,4-diaminotoluene results in increased expression of ARHGAP11A mRNA
CTD
PMID:20713471
NCBI chr 2:113,661,837...113,679,006
Ensembl chr 2:113,661,837...113,679,006
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Arhgap22
Rho GTPase activating protein 22
increases expression
EXP
2,4-diaminotoluene results in increased expression of ARHGAP22 mRNA
CTD
PMID:20713471
NCBI chr14:32,935,952...33,091,893
Ensembl chr14:32,935,983...33,091,891
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Arrdc3
arrestin domain containing 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of ARRDC3 mRNA
CTD
PMID:20713471
NCBI chr13:81,031,508...81,044,161
Ensembl chr13:81,031,503...81,044,161
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Asf1b
anti-silencing function 1B histone chaperone
increases expression
EXP
2,4-diaminotoluene results in increased expression of ASF1B mRNA
CTD
PMID:20713471
NCBI chr 8:84,682,323...84,696,824
Ensembl chr 8:84,682,136...84,696,826
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Aspn
asporin
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of ASPN mRNA
CTD
PMID:20713471
NCBI chr13:49,697,919...49,721,041
Ensembl chr13:49,697,919...49,721,041
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Atp6v1d
ATPase, H+ transporting, lysosomal V1 subunit D
increases expression
ISO
2,4-diaminotoluene results in increased expression of ATP6V1D mRNA
CTD
PMID:17070881
NCBI chr12:78,889,756...78,908,810
Ensembl chr12:78,887,499...78,908,412
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Bax
BCL2-associated X protein
increases expression
ISO
2,4-diaminotoluene results in increased expression of BAX mRNA
CTD
PMID:17070881
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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Birc5
baculoviral IAP repeat-containing 5
increases expression
EXP
2,4-diaminotoluene results in increased expression of BIRC5 mRNA
CTD
PMID:20713471
NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
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Btg2
BTG anti-proliferation factor 2
increases expression
EXP ISO
2,4-diaminotoluene results in increased expression of BTG2 mRNA
CTD
PMID:17070881 PMID:20713471
NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
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C1s1
complement component 1, s subcomponent 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of C1S mRNA
CTD
PMID:20713471
NCBI chr 6:124,507,303...124,519,340
Ensembl chr 6:124,507,304...124,519,318
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C7
complement component 7
increases expression
ISO
2,4-diaminotoluene results in increased expression of C7 mRNA
CTD
PMID:17070881
NCBI chr15:5,017,232...5,093,230
Ensembl chr15:5,018,244...5,093,222
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Calr3
calreticulin 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of CALR3 mRNA
CTD
PMID:20713471
NCBI chr 8:73,178,020...73,197,638
Ensembl chr 8:73,178,020...73,197,714
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Casp3
caspase 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of CASP3 mRNA
CTD
PMID:20713471
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Cblc
Casitas B-lineage lymphoma c
increases expression
ISO
2,4-diaminotoluene results in increased expression of CBLC mRNA
CTD
PMID:17070881
NCBI chr 7:19,513,643...19,530,734
Ensembl chr 7:19,512,806...19,530,734
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Ccl2
C-C motif chemokine ligand 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of CCL2 mRNA
CTD
PMID:20713471
NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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Ccl8
C-C motif chemokine ligand 8
increases expression
EXP
2,4-diaminotoluene results in increased expression of CCL8 mRNA
CTD
PMID:20713471
NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625
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Ccn1
cellular communication network factor 1
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of CCN1 mRNA
CTD
PMID:20713471
NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
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Ccna2
cyclin A2
increases expression
EXP
2,4-diaminotoluene results in increased expression of CCNA2 mRNA
CTD
PMID:20713471
NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
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Ccnb2
cyclin B2
increases expression
EXP
2,4-diaminotoluene results in increased expression of CCNB2 mRNA
CTD
PMID:20713471
NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829
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Ccng1
cyclin G1
increases expression
ISO
2,4-diaminotoluene results in increased expression of CCNG1 mRNA
CTD
PMID:17070881
NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
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Cd276
CD276 antigen
increases expression
ISO
2,4-diaminotoluene results in increased expression of CD276 mRNA
CTD
PMID:17070881
NCBI chr 9:58,431,581...58,463,437
Ensembl chr 9:58,431,581...58,462,720
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Cd300lb
CD300 molecule like family member B
increases expression
EXP
2,4-diaminotoluene results in increased expression of CD300LB mRNA
CTD
PMID:20713471
NCBI chr11:114,813,605...114,825,197
Ensembl chr11:114,813,607...114,825,212
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Cd48
CD48 antigen
increases expression
EXP
2,4-diaminotoluene results in increased expression of CD48 mRNA
CTD
PMID:20713471
NCBI chr 1:171,508,989...171,532,825
Ensembl chr 1:171,509,577...171,532,826
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Cda
cytidine deaminase
increases expression
EXP
2,4-diaminotoluene results in increased expression of CDA mRNA
CTD
PMID:20713471
NCBI chr 4:138,065,839...138,095,623
Ensembl chr 4:138,065,735...138,095,303
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Cdc45
cell division cycle 45
increases expression
EXP
2,4-diaminotoluene results in increased expression of CDC45 mRNA
CTD
PMID:20713471
NCBI chr16:18,599,202...18,632,371
Ensembl chr16:18,599,197...18,630,737
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Cdc6
cell division cycle 6
increases expression
EXP
2,4-diaminotoluene results in increased expression of CDC6 mRNA
CTD
PMID:20713471
NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
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Cdca8
cell division cycle associated 8
increases expression
EXP
2,4-diaminotoluene results in increased expression of CDCA8 mRNA
CTD
PMID:20713471
NCBI chr 4:124,812,258...124,830,710
Ensembl chr 4:124,812,258...124,833,104
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Cdkn1a
cyclin dependent kinase inhibitor 1A
increases expression
EXP ISO
2,4-diaminotoluene results in increased expression of CDKN1A mRNA
CTD
PMID:17070881 PMID:20713471
NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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Cdt1
chromatin licensing and DNA replication factor 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of CDT1 mRNA
CTD
PMID:20713471
NCBI chr 8:123,294,754...123,299,869
Ensembl chr 8:123,294,754...123,300,293
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Cenpu
centromere protein U
increases expression
EXP
2,4-diaminotoluene results in increased expression of CENPU mRNA
CTD
PMID:20713471
NCBI chr 8:47,005,054...47,033,603
Ensembl chr 8:47,005,063...47,033,042
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Cep43
centrosomal protein 43
increases expression
EXP
2,4-diaminotoluene results in increased expression of CEP43 mRNA
CTD
PMID:20713471
NCBI chr17:8,383,976...8,415,309
Ensembl chr17:8,384,333...8,415,636
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Ces3b
carboxylesterase 3B
increases expression
EXP
2,4-diaminotoluene results in increased expression of CES3 mRNA
CTD
PMID:20713471
NCBI chr 8:105,810,365...105,820,561
Ensembl chr 8:105,810,385...105,820,561
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Chac1
ChaC, cation transport regulator 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of CHAC1 mRNA
CTD
PMID:20713471
NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862
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Ckap2
cytoskeleton associated protein 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of CKAP2 mRNA
CTD
PMID:20713471
NCBI chr 8:22,658,168...22,675,835
Ensembl chr 8:22,658,176...22,675,835
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Cntn1
contactin 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of CNTN1 mRNA
CTD
PMID:20713471
NCBI chr15:91,949,034...92,239,834
Ensembl chr15:91,949,046...92,239,848
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Col5a2
collagen, type V, alpha 2
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of COL5A2 mRNA
CTD
PMID:20713471
NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442
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Cpox
coproporphyrinogen oxidase
increases expression
EXP
2,4-diaminotoluene results in increased expression of CPOX mRNA
CTD
PMID:20713471
NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
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Cpq
carboxypeptidase Q
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of CPQ mRNA
CTD
PMID:17070881
NCBI chr15:33,083,275...33,594,698
Ensembl chr15:33,083,275...33,594,698
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Crebl2
cAMP responsive element binding protein-like 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of CREBL2 mRNA
CTD
PMID:20713471
NCBI chr 6:134,807,090...134,835,894
Ensembl chr 6:134,807,117...134,835,894
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Cryab
crystallin, alpha B
increases expression
ISO
2,4-diaminotoluene results in increased expression of CRYAB mRNA
CTD
PMID:17070881
NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936
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Cx3cl1
C-X3-C motif chemokine ligand 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of CX3CL1 mRNA
CTD
PMID:20713471
NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
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Cxcl15
C-X-C motif chemokine ligand 15
multiple interactions
ISO
[2,4-diaminotoluene co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA
CTD
PMID:29594315
NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
ISO EXP
2,4-diaminotoluene results in increased expression of CYP1A1 protein 2,4-diaminotoluene results in increased expression of CYP1A1 mRNA
CTD
PMID:8685904 PMID:20713471
NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
ISO
2,4-diaminotoluene results in increased expression of CYP1A2 protein
CTD
PMID:8685904
NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of CYP1B1 mRNA
CTD
PMID:20713471
NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
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Ddah1
dimethylarginine dimethylaminohydrolase 1
increases expression
ISO
2,4-diaminotoluene results in increased expression of DDAH1 mRNA
CTD
PMID:17070881
NCBI chr 3:145,464,447...145,600,032
Ensembl chr 3:145,464,430...145,600,032
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Ddit3
DNA-damage inducible transcript 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of DDIT3 mRNA
CTD
PMID:22016648
NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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Depdc1b
DEP domain containing 1B
increases expression
EXP
2,4-diaminotoluene results in increased expression of DEPDC1B mRNA
CTD
PMID:20713471
NCBI chr13:108,452,592...108,526,100
Ensembl chr13:108,452,866...108,544,316
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Dmp1
dentin matrix protein 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of DMP1 mRNA
CTD
PMID:20713471
NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968
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Dnaja2
DnaJ heat shock protein family (Hsp40) member A2
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of DNAJA2 mRNA
CTD
PMID:22016648
NCBI chr 8:86,264,262...86,281,990
Ensembl chr 8:86,264,262...86,281,973
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Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
increases expression
EXP
2,4-diaminotoluene results in increased expression of DNAJB9 mRNA
CTD
PMID:20713471
NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
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Dusp1
dual specificity phosphatase 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of DUSP1 mRNA
CTD
PMID:20713471
NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
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Dusp4
dual specificity phosphatase 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of DUSP4 mRNA
CTD
PMID:20713471
NCBI chr 8:35,274,448...35,289,106
Ensembl chr 8:35,274,451...35,287,048
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Dusp6
dual specificity phosphatase 6
increases expression
EXP
2,4-diaminotoluene results in increased expression of DUSP6 mRNA
CTD
PMID:20713471
NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
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Dyrk2
dual-specificity tyrosine phosphorylation regulated kinase 2
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of DYRK2 mRNA
CTD
PMID:20713471
NCBI chr10:118,691,507...118,725,144
Ensembl chr10:118,691,508...118,706,114
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E2f7
E2F transcription factor 7
increases expression
EXP
2,4-diaminotoluene results in increased expression of E2F7 mRNA
CTD
PMID:20713471
NCBI chr10:110,580,799...110,623,245
Ensembl chr10:110,581,300...110,623,245
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E2f8
E2F transcription factor 8
increases expression
EXP
2,4-diaminotoluene results in increased expression of E2F8 mRNA
CTD
PMID:20713471
NCBI chr 7:48,516,177...48,531,821
Ensembl chr 7:48,516,177...48,531,344
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Eda2r
ectodysplasin A2 receptor
increases expression
EXP
2,4-diaminotoluene results in increased expression of EDA2R mRNA
CTD
PMID:20713471
NCBI chr X:96,375,936...96,420,786
Ensembl chr X:96,377,446...96,420,822
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Eif1a
eukaryotic translation initiation factor 1A
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of EIF1A mRNA
CTD
PMID:20713471
NCBI chr18:46,730,771...46,743,292
Ensembl chr18:46,730,768...46,749,523
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Emp1
epithelial membrane protein 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of EMP1 mRNA
CTD
PMID:20713471
NCBI chr 6:135,339,548...135,360,171
Ensembl chr 6:135,339,543...135,360,171
G
Epcam
epithelial cell adhesion molecule
increases expression
ISO
2,4-diaminotoluene results in increased expression of EPCAM mRNA
CTD
PMID:17070881
NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
G
Ephx1
epoxide hydrolase 1, microsomal
increases expression
ISO
2,4-diaminotoluene results in increased expression of EPHX1 mRNA
CTD
PMID:17070881
NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
G
Ereg
epiregulin
increases expression
EXP
2,4-diaminotoluene results in increased expression of EREG mRNA
CTD
PMID:20713471
NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
G
Espl1
extra spindle pole bodies 1, separase
increases expression
EXP
2,4-diaminotoluene results in increased expression of ESPL1 mRNA
CTD
PMID:20713471
NCBI chr15:102,204,688...102,232,792
Ensembl chr15:102,204,701...102,232,792
G
Etv1
ets variant 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of ETV1 mRNA
CTD
PMID:20713471
NCBI chr12:38,829,655...38,920,484
Ensembl chr12:38,829,379...38,920,483
G
Etv5
ets variant 5
increases expression
EXP
2,4-diaminotoluene results in increased expression of ETV5 mRNA
CTD
PMID:20713471
NCBI chr16:22,200,063...22,258,320
Ensembl chr16:22,200,059...22,258,469
G
Exo1
exonuclease 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of EXO1 mRNA
CTD
PMID:20713471
NCBI chr 1:175,708,334...175,738,962
Ensembl chr 1:175,708,147...175,741,055
G
Fabp4
fatty acid binding protein 4, adipocyte
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of FABP4 mRNA
CTD
PMID:22016648
NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
G
Fas
Fas cell surface death receptor
increases expression
ISO
2,4-diaminotoluene results in increased expression of FAS mRNA
CTD
PMID:17070881
NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
G
Fdps
farnesyl diphosphate synthetase
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of FDPS mRNA
CTD
PMID:20713471
NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266
G
Fhit
fragile histidine triad gene
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of FHIT mRNA
CTD
PMID:17070881
NCBI chr14:11,307,718...12,919,681
Ensembl chr14:11,307,738...12,919,681
G
Fignl1
fidgetin-like 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of FIGNL1 mRNA
CTD
PMID:20713471
NCBI chr11:11,737,429...11,758,962
Ensembl chr11:11,737,431...11,758,962
G
Fosl1
fos-like antigen 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of FOSL1 mRNA
CTD
PMID:20713471
NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
G
Ftl1
ferritin light polypeptide 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of FTL1 mRNA
CTD
PMID:22016648
NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
G
Fut8
fucosyltransferase 8
increases expression
EXP
2,4-diaminotoluene results in increased expression of FUT8 mRNA
CTD
PMID:20713471
NCBI chr12:77,284,878...77,522,770
Ensembl chr12:77,284,899...77,523,112
G
Fxyd5
FXYD domain-containing ion transport regulator 5
increases expression
EXP
2,4-diaminotoluene results in increased expression of FXYD5 mRNA
CTD
PMID:20713471
NCBI chr 7:30,732,153...30,741,565
Ensembl chr 7:30,732,147...30,741,906
G
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
increases expression
EXP
2,4-diaminotoluene results in increased expression of GADD45A mRNA
CTD
PMID:20713471
NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
G
Gas2l3
growth arrest-specific 2 like 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of GAS2L3 mRNA
CTD
PMID:20713471
NCBI chr10:89,244,684...89,279,935
Ensembl chr10:89,244,685...89,279,829
G
Gcat
glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
increases expression
EXP
2,4-diaminotoluene results in increased expression of GCAT mRNA
CTD
PMID:20713471
NCBI chr15:78,915,074...78,926,731
Ensembl chr15:78,915,074...78,922,553 Ensembl chr15:78,915,074...78,922,553
G
Gch1
GTP cyclohydrolase 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of GCH1 mRNA
CTD
PMID:20713471
NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870
G
Gchfr
GTP cyclohydrolase I feedback regulator
increases expression
EXP
2,4-diaminotoluene results in increased expression of GCHFR mRNA
CTD
PMID:20713471
NCBI chr 2:118,998,269...119,002,870
Ensembl chr 2:118,998,254...119,002,871
G
Gins4
GINS complex subunit 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of GINS4 mRNA
CTD
PMID:20713471
NCBI chr 8:23,716,626...23,727,684
Ensembl chr 8:23,716,632...23,727,675
G
Gja1
gap junction protein, alpha 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of GJA1 mRNA
CTD
PMID:20713471
NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
G
Gnb4
guanine nucleotide binding protein (G protein), beta 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of GNB4 mRNA
CTD
PMID:20713471
NCBI chr 3:32,632,736...32,670,813
Ensembl chr 3:32,634,481...32,670,734
G
Gpc1
glypican 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of GPC1 mRNA
CTD
PMID:20713471
NCBI chr 1:92,759,367...92,787,933
Ensembl chr 1:92,759,367...92,788,501
G
Gpnmb
glycoprotein (transmembrane) nmb
increases expression
EXP
2,4-diaminotoluene results in increased expression of GPNMB mRNA
CTD
PMID:20713471
NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
G
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
increases expression
ISO
2,4-diaminotoluene results in increased expression of GRIA3 mRNA
CTD
PMID:17070881
NCBI chr X:40,489,351...40,767,478
Ensembl chr X:40,489,731...40,767,478
G
Gsdme
gasdermin E
increases expression
EXP
2,4-diaminotoluene results in increased expression of GSDME mRNA
CTD
PMID:20713471
NCBI chr 6:50,167,013...50,240,837
Ensembl chr 6:50,165,868...50,240,842
G
Gstm1
glutathione S-transferase, mu 1
increases expression
ISO
2,4-diaminotoluene results in increased expression of GSTM1 mRNA
CTD
PMID:17070881
NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
G
Gtdc1
glycosyltransferase-like domain containing 1
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of GTDC1 mRNA
CTD
PMID:20713471
NCBI chr 2:44,454,420...44,817,761
Ensembl chr 2:44,454,424...44,817,669
G
Gtse1
G two S phase expressed protein 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of GTSE1 mRNA
CTD
PMID:20713471
NCBI chr15:85,743,928...85,760,774
Ensembl chr15:85,743,946...85,760,774
G
H1f0
H1.0 linker histone
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of H1F0 mRNA
CTD
PMID:20713471
NCBI chr15:78,912,412...78,914,704
Ensembl chr15:78,912,650...78,914,704
G
H2-D1
histocompatibility 2, D region locus 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of H2-D1 mRNA
CTD
PMID:20713471
NCBI chr17:35,482,070...35,486,473
Ensembl chr17:35,481,706...35,486,475
G
H2ax
H2A.X variant histone
decreases expression increases phosphorylation
EXP ISO
2,4-diaminotoluene results in decreased expression of H2AX mRNA 2,4-diaminotoluene results in increased phosphorylation of H2AX protein
CTD
PMID:20713471 PMID:34510228
NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
G
H3f3b
H3.3 histone B
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of H3F3B mRNA
CTD
PMID:20713471
NCBI chr11:115,912,787...115,921,313
Ensembl chr11:115,912,738...115,918,788
G
H4c12
H4 clustered histone 12
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of H4C8 mRNA
CTD
PMID:20713471
NCBI chr13:21,934,315...21,934,723
Ensembl chr13:21,934,364...21,934,675
G
H4c8
H4 clustered histone 8
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of H4C9 mRNA
CTD
PMID:20713471
NCBI chr13:23,715,214...23,715,648
Ensembl chr13:23,715,220...23,715,689
G
Hacd2
3-hydroxyacyl-CoA dehydratase 2
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of HACD2 mRNA
CTD
PMID:20713471
NCBI chr16:34,842,791...34,929,560
Ensembl chr16:34,842,798...34,929,547
G
Hba-a1
hemoglobin alpha, adult chain 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of HBA-A1 mRNA
CTD
PMID:20713471
NCBI chr11:32,233,672...32,234,486
Ensembl chr11:32,233,511...32,234,465
G
Higd1a
HIG1 domain family, member 1A
increases expression
EXP
2,4-diaminotoluene results in increased expression of HIGD1A mRNA
CTD
PMID:20713471
NCBI chr 9:121,677,623...121,686,862
Ensembl chr 9:121,677,629...121,687,428
G
Hmga1
high mobility group AT-hook 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of HMGA1 mRNA
CTD
PMID:20713471
NCBI chr17:27,774,798...27,782,649
Ensembl chr17:27,775,471...27,782,648
G
Hmga2
high mobility group AT-hook 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of HMGA2 mRNA
CTD
PMID:20713471
NCBI chr10:120,197,173...120,312,374
Ensembl chr10:120,197,180...120,312,374
G
Hmgcs1
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of HMGCS1 mRNA
CTD
PMID:20713471
NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
G
Hmmr
hyaluronan mediated motility receptor (RHAMM)
increases expression
EXP
2,4-diaminotoluene results in increased expression of HMMR mRNA
CTD
PMID:20713471
NCBI chr11:40,592,215...40,624,290
Ensembl chr11:40,592,222...40,624,249
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of HSD17B4 mRNA
CTD
PMID:22016648
NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
G
Hsd17b6
hydroxysteroid (17-beta) dehydrogenase 6
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of HSD17B6 mRNA
CTD
PMID:17070881
NCBI chr10:127,826,800...127,843,517
Ensembl chr10:127,826,805...127,843,480
G
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of HSP90AB1 mRNA
CTD
PMID:22016648
NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197
G
Ier3
immediate early response 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of IER3 mRNA
CTD
PMID:20713471
NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
G
Ifi30
interferon gamma inducible protein 30
increases expression
EXP
2,4-diaminotoluene results in increased expression of IFI30 mRNA
CTD
PMID:20713471
NCBI chr 8:71,215,418...71,219,307
Ensembl chr 8:71,215,419...71,219,307
G
Ifng
interferon gamma
multiple interactions
ISO
[2,4-diaminotoluene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA
CTD
PMID:29594315
NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
G
Il12rb1
interleukin 12 receptor, beta 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of IL12RB1 mRNA
CTD
PMID:20713471
NCBI chr 8:71,261,005...71,276,186
Ensembl chr 8:71,261,093...71,274,068
G
Il1rl1
interleukin 1 receptor-like 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of IL1RL1 mRNA
CTD
PMID:20713471
NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575
G
Il2ra
interleukin 2 receptor, alpha chain
increases expression
ISO
2,4-diaminotoluene results in increased expression of IL2RA mRNA
CTD
PMID:17070881
NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
G
Iqgap3
IQ motif containing GTPase activating protein 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of IQGAP3 mRNA
CTD
PMID:20713471
NCBI chr 3:87,989,309...88,028,355
Ensembl chr 3:87,989,278...88,028,355
G
Jarid2
jumonji and AT-rich interaction domain containing 2
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of JARID2 mRNA
CTD
PMID:20713471
NCBI chr13:44,881,817...45,075,119
Ensembl chr13:44,882,950...45,075,119
G
Jun
jun proto-oncogene
increases expression
EXP
2,4-diaminotoluene results in increased expression of JUN mRNA
CTD
PMID:20713471
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
G
Kcnk2
potassium channel, subfamily K, member 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of KCNK2 mRNA
CTD
PMID:20713471
NCBI chr 1:188,940,127...189,134,951
Ensembl chr 1:188,940,127...189,134,470
G
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of KCNN4 mRNA
CTD
PMID:20713471
NCBI chr 7:24,069,750...24,084,635
Ensembl chr 7:24,069,688...24,086,115
G
Kif2c
kinesin family member 2C
increases expression
EXP
2,4-diaminotoluene results in increased expression of KIF2C mRNA
CTD
PMID:20713471
NCBI chr 4:117,016,830...117,039,821
Ensembl chr 4:117,016,836...117,039,836
G
Kitl
kit ligand
increases expression
EXP
2,4-diaminotoluene results in increased expression of KITL mRNA
CTD
PMID:20713471
NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
G
Klhdc8a
kelch domain containing 8A
increases expression
EXP
2,4-diaminotoluene results in increased expression of KLHDC8A mRNA
CTD
PMID:20713471
NCBI chr 1:132,226,352...132,236,216
Ensembl chr 1:132,226,364...132,235,095
G
Krt7
keratin 7
increases expression
EXP
2,4-diaminotoluene results in increased expression of KRT7 mRNA
CTD
PMID:20713471
NCBI chr15:101,310,284...101,325,687
Ensembl chr15:101,308,924...101,328,194
G
L3mbtl3
L3MBTL3 histone methyl-lysine binding protein
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of L3MBTL3 mRNA
CTD
PMID:20713471
NCBI chr10:26,150,361...26,252,426
Ensembl chr10:26,150,366...26,251,967
G
Lgals2
lectin, galactose-binding, soluble 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of LGALS2 mRNA
CTD
PMID:20713471
NCBI chr15:78,735,060...78,739,729
Ensembl chr15:78,735,060...78,739,729
G
Lif
leukemia inhibitory factor
increases expression
EXP
2,4-diaminotoluene results in increased expression of LIF mRNA
CTD
PMID:20713471
NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514
G
Lmnb1
lamin B1
increases expression
EXP
2,4-diaminotoluene results in increased expression of LMNB1 mRNA
CTD
PMID:20713471
NCBI chr18:56,840,885...56,886,496
Ensembl chr18:56,840,885...56,886,496
G
Lrr1
leucine rich repeat protein 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of LRR1 mRNA
CTD
PMID:20713471
NCBI chr12:69,215,588...69,225,786
Ensembl chr12:69,215,588...69,225,783
G
Lrrc8d
leucine rich repeat containing 8D
increases expression
EXP
2,4-diaminotoluene results in increased expression of LRRC8D mRNA
CTD
PMID:20713471
NCBI chr 5:105,847,829...105,963,081
Ensembl chr 5:105,847,835...105,980,302
G
Ly6a
lymphocyte antigen 6 family member A
increases expression
EXP
2,4-diaminotoluene results in increased expression of LY6A mRNA
CTD
PMID:20713471
NCBI chr15:74,866,726...74,869,880
Ensembl chr15:74,866,726...74,869,880
G
Ly6e
lymphocyte antigen 6 family member E
increases expression
EXP
2,4-diaminotoluene results in increased expression of LY6E mRNA
CTD
PMID:20713471
NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752
G
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
increases expression
EXP
2,4-diaminotoluene results in increased expression of MALAT1 mRNA
CTD
PMID:20713471
NCBI chr19:5,845,718...5,852,700
Ensembl chr19:5,845,717...5,853,602
G
Mcm3
minichromosome maintenance complex component 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of MCM3 mRNA
CTD
PMID:20713471
NCBI chr 1:20,873,188...20,890,536
Ensembl chr 1:20,873,192...20,890,536
G
Mcm5
minichromosome maintenance complex component 5
increases expression
EXP
2,4-diaminotoluene results in increased expression of MCM5 mRNA
CTD
PMID:20713471
NCBI chr 8:75,836,096...75,855,067
Ensembl chr 8:75,836,197...75,855,067
G
Mgmt
O-6-methylguanine-DNA methyltransferase
increases expression affects expression
ISO
2,4-diaminotoluene results in increased expression of MGMT mRNA 2,4-diaminotoluene affects the expression of MGMT mRNA
CTD
PMID:17070881 PMID:22084566
NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
G
Mmp13
matrix metallopeptidase 13
increases expression
EXP
2,4-diaminotoluene results in increased expression of MMP13 mRNA
CTD
PMID:20713471
NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
G
Mmp3
matrix metallopeptidase 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of MMP3 mRNA
CTD
PMID:20713471
NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
G
Mmp9
matrix metallopeptidase 9
increases expression
EXP
2,4-diaminotoluene results in increased expression of MMP9 mRNA
CTD
PMID:20713471
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
G
Msln
mesothelin
increases expression
EXP
2,4-diaminotoluene results in increased expression of MSLN mRNA
CTD
PMID:20713471
NCBI chr17:25,967,587...25,973,352
Ensembl chr17:25,967,587...25,973,352
G
Mvd
mevalonate (diphospho) decarboxylase
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of MVD mRNA
CTD
PMID:20713471
NCBI chr 8:123,160,335...123,170,161
Ensembl chr 8:123,160,340...123,170,161
G
Myo1c
myosin IC
increases expression
EXP
2,4-diaminotoluene results in increased expression of MYO1C mRNA
CTD
PMID:20713471
NCBI chr11:75,541,345...75,565,450
Ensembl chr11:75,541,330...75,564,736
G
Ncapg2
non-SMC condensin II complex, subunit G2
increases expression
EXP
2,4-diaminotoluene results in increased expression of NCAPG2 mRNA
CTD
PMID:20713471
NCBI chr12:116,368,969...116,427,152
Ensembl chr12:116,369,022...116,427,351
G
Ncf4
neutrophil cytosolic factor 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of NCF4 mRNA
CTD
PMID:20713471
NCBI chr15:78,128,324...78,146,782
Ensembl chr15:78,129,001...78,146,780
G
Ndc80
NDC80 kinetochore complex component
increases expression
EXP
2,4-diaminotoluene results in increased expression of NDC80 mRNA
CTD
PMID:20713471
NCBI chr17:71,803,095...71,833,852
Ensembl chr17:71,803,095...71,833,852
G
Neil3
nei like 3 (E. coli)
increases expression
EXP
2,4-diaminotoluene results in increased expression of NEIL3 mRNA
CTD
PMID:20713471
NCBI chr 8:54,039,902...54,092,100
Ensembl chr 8:54,039,902...54,092,100
G
Niban1
niban apoptosis regulator 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of NIBAN1 mRNA
CTD
PMID:20713471
NCBI chr 1:151,447,215...151,597,690
Ensembl chr 1:151,446,937...151,597,690
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Nolc1
nucleolar and coiled-body phosphoprotein 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of NOLC1 mRNA
CTD
PMID:20713471
NCBI chr19:46,064,286...46,073,982
Ensembl chr19:46,064,302...46,073,969
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Nqo1
NAD(P)H dehydrogenase, quinone 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of NQO1 mRNA
CTD
PMID:20713471
NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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Nrep
neuronal regeneration related protein
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of NREP mRNA
CTD
PMID:20713471
NCBI chr18:33,570,072...33,597,444
Ensembl chr18:33,570,072...33,597,082
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Nupr1
nuclear protein transcription regulator 1
increases expression decreases expression
EXP ISO
2,4-diaminotoluene results in increased expression of NUPR1 mRNA 2,4-diaminotoluene results in decreased expression of NUPR1 mRNA
CTD
PMID:17070881 PMID:20713471
NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
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Oat
ornithine aminotransferase
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of OAT mRNA
CTD
PMID:22016648
NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
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Ogn
osteoglycin
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of OGN mRNA
CTD
PMID:20713471
NCBI chr13:49,761,491...49,777,977
Ensembl chr13:49,761,522...49,777,977
G
Ormdl3
ORM1-like 3 (S. cerevisiae)
increases expression
EXP
2,4-diaminotoluene results in increased expression of ORMDL3 mRNA
CTD
PMID:20713471
NCBI chr11:98,472,120...98,478,071
Ensembl chr11:98,472,082...98,478,194
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P2rx7
purinergic receptor P2X, ligand-gated ion channel, 7
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of P2RX7 mRNA
CTD
PMID:20713471
NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
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Pard3
par-3 family cell polarity regulator
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of PARD3 mRNA
CTD
PMID:20713471
NCBI chr 8:127,790,131...128,338,767
Ensembl chr 8:127,790,643...128,338,767
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Pbk
PDZ binding kinase
increases expression
EXP
2,4-diaminotoluene results in increased expression of PBK mRNA
CTD
PMID:20713471
NCBI chr14:66,043,337...66,055,271
Ensembl chr14:66,043,286...66,055,271
G
Pcdh18
protocadherin 18
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of PCDH18 mRNA
CTD
PMID:20713471
NCBI chr 3:49,697,745...49,711,723
Ensembl chr 3:49,697,745...49,711,774
G
Pcdh7
protocadherin 7
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of PCDH7 mRNA
CTD
PMID:20713471
NCBI chr 5:57,873,487...58,290,578
Ensembl chr 5:57,875,309...58,290,572
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Pcdhb22
protocadherin beta 22
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of PCDHB22 mRNA
CTD
PMID:20713471
NCBI chr18:37,651,402...37,657,532
Ensembl chr18:37,650,924...37,657,532
G
Pdrg1
p53 and DNA damage regulated 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of PDRG1 mRNA
CTD
PMID:20713471
NCBI chr 2:152,850,810...152,857,939
Ensembl chr 2:152,850,810...152,857,347
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Pgam2
phosphoglycerate mutase 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of PGAM2 mRNA
CTD
PMID:22016648
NCBI chr11:5,751,637...5,753,796
Ensembl chr11:5,751,640...5,753,733
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Phex
phosphate regulating endopeptidase homolog, X-linked
increases expression
EXP
2,4-diaminotoluene results in increased expression of PHEX mRNA
CTD
PMID:20713471
NCBI chr X:155,945,071...156,198,282
Ensembl chr X:155,945,071...156,198,308
G
Phf11d
PHD finger protein 11D
increases expression
EXP
2,4-diaminotoluene results in increased expression of PHF11D mRNA
CTD
PMID:20713471
NCBI chr14:59,584,646...59,608,004
Ensembl chr14:59,584,856...59,602,919
G
Phlda3
pleckstrin homology like domain, family A, member 3
increases expression
ISO
2,4-diaminotoluene results in increased expression of PHLDA3 mRNA
CTD
PMID:17070881
NCBI chr 1:135,693,823...135,696,872
Ensembl chr 1:135,693,857...135,696,874
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Pola1
polymerase (DNA directed), alpha 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of POLA1 mRNA
CTD
PMID:20713471
NCBI chr X:92,348,372...92,675,993
Ensembl chr X:92,348,373...92,675,761
G
Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
EXP
2,4-diaminotoluene results in increased expression of PPP1R15A mRNA
CTD
PMID:20713471
NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
G
Prdx1
peroxiredoxin 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of PRDX1 mRNA
CTD
PMID:22016648
NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
G
Prdx3
peroxiredoxin 3
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of PRDX3 mRNA
CTD
PMID:22016648
NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994
G
Psrc1
proline/serine-rich coiled-coil 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of PSRC1 mRNA
CTD
PMID:20713471
NCBI chr 3:108,291,120...108,295,547
Ensembl chr 3:108,291,155...108,295,547
G
Ptgfr
prostaglandin F receptor
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of PTGFR mRNA
CTD
PMID:20713471
NCBI chr 3:151,504,247...151,543,165
Ensembl chr 3:151,502,139...151,543,267
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of PTGS2 mRNA
CTD
PMID:20713471
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
G
Ptpn6
protein tyrosine phosphatase, non-receptor type 6
increases expression
EXP
2,4-diaminotoluene results in increased expression of PTPN6 mRNA
CTD
PMID:20713471
NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677
G
Ptx3
pentraxin related gene
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of PTX3 mRNA
CTD
PMID:20713471
NCBI chr 3:66,127,308...66,133,227
Ensembl chr 3:66,127,331...66,133,226
G
Pvr
poliovirus receptor
increases expression
EXP
2,4-diaminotoluene results in increased expression of PVR mRNA
CTD
PMID:20713471
NCBI chr 7:19,637,503...19,655,068
Ensembl chr 7:19,637,503...19,655,085
G
Rad51
RAD51 recombinase
increases expression
EXP
2,4-diaminotoluene results in increased expression of RAD51 mRNA
CTD
PMID:20713471
NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926
G
Rad51ap1
RAD51 associated protein 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of RAD51AP1 mRNA
CTD
PMID:20713471
NCBI chr 6:126,900,378...126,916,664
Ensembl chr 6:126,900,013...126,916,550
G
Rad54l
RAD54 like (S. cerevisiae)
increases expression
EXP
2,4-diaminotoluene results in increased expression of RAD54L mRNA
CTD
PMID:20713471
NCBI chr 4:115,951,458...115,980,875
Ensembl chr 4:115,951,461...115,980,887
G
Rassf1
Ras association (RalGDS/AF-6) domain family member 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of RASSF1 mRNA
CTD
PMID:20713471
NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466
G
Rbm3
RNA binding motif (RNP1, RRM) protein 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of RBM3 mRNA
CTD
PMID:20713471
NCBI chr X:8,005,214...8,012,119
Ensembl chr X:8,005,214...8,012,119
G
Rbmx
RNA binding motif protein, X chromosome
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of RBMX mRNA
CTD
PMID:20713471
NCBI chr X:56,428,708...56,438,405
Ensembl chr X:56,428,890...56,438,396
G
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
increases expression
EXP
2,4-diaminotoluene results in increased expression of RBPJ mRNA
CTD
PMID:20713471
NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704
G
Rfc3
replication factor C (activator 1) 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of RFC3 mRNA
CTD
PMID:20713471
NCBI chr 5:151,566,282...151,574,673
Ensembl chr 5:151,566,221...151,574,707
G
Rfc4
replication factor C (activator 1) 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of RFC4 mRNA
CTD
PMID:20713471
NCBI chr16:22,932,698...22,946,480
Ensembl chr16:22,932,693...22,946,487
G
Rhobtb2
Rho-related BTB domain containing 2
increases expression
ISO
2,4-diaminotoluene results in increased expression of RHOBTB2 mRNA
CTD
PMID:17070881
NCBI chr14:70,022,439...70,062,296
Ensembl chr14:70,022,439...70,043,085
G
Rngtt
RNA guanylyltransferase and 5'-phosphatase
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of RNGTT mRNA
CTD
PMID:20713471
NCBI chr 4:33,310,300...33,502,610
Ensembl chr 4:33,310,311...33,502,614
G
Rrm2
ribonucleotide reductase M2
increases expression
EXP
2,4-diaminotoluene results in increased expression of RRM2 mRNA
CTD
PMID:20713471
NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145
G
Rrm2b
ribonucleotide reductase M2 B (TP53 inducible)
increases expression
ISO
2,4-diaminotoluene results in increased expression of RRM2B mRNA
CTD
PMID:21704725
NCBI chr15:37,924,196...37,961,562
Ensembl chr15:37,924,196...37,961,562
G
Rsad2
radical S-adenosyl methionine domain containing 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of RSAD2 mRNA
CTD
PMID:20713471
NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451
G
Rtp4
receptor transporter protein 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of RTP4 mRNA
CTD
PMID:20713471
NCBI chr16:23,338,976...23,432,972
Ensembl chr16:23,339,041...23,432,972
G
Saa3
serum amyloid A 3
increases expression
EXP
2,4-diaminotoluene results in increased expression of SAA3 mRNA
CTD
PMID:22016648
NCBI chr 7:46,361,422...46,365,100
Ensembl chr 7:46,361,422...46,365,124
G
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of SEMA3C mRNA
CTD
PMID:20713471
NCBI chr 5:17,779,814...17,935,266
Ensembl chr 5:17,779,279...17,935,266
G
Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
increases expression
EXP
2,4-diaminotoluene results in increased expression of SEMA5A mRNA
CTD
PMID:20713471
NCBI chr15:32,244,959...32,696,487
Ensembl chr15:32,244,956...32,696,487
G
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
increases expression
EXP
2,4-diaminotoluene results in increased expression of SEMA6D mRNA
CTD
PMID:20713471
NCBI chr 2:123,931,089...124,509,711
Ensembl chr 2:123,931,889...124,509,690
G
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
increases expression
EXP
2,4-diaminotoluene results in increased expression of SEMA7A mRNA
CTD
PMID:20713471
NCBI chr 9:57,846,879...57,870,148
Ensembl chr 9:57,847,395...57,870,148
G
Serpina7
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
increases expression
ISO
2,4-diaminotoluene results in increased expression of SERPINA7 mRNA
CTD
PMID:17070881
NCBI chr X:137,979,998...137,985,985
Ensembl chr X:137,980,006...137,985,985
G
Serpine1
serine (or cysteine) peptidase inhibitor, clade E, member 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of SERPINE1 mRNA
CTD
PMID:22016648
NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
G
Shbg
sex hormone binding globulin
increases expression
ISO
2,4-diaminotoluene results in increased expression of SHBG protein
CTD
PMID:3199457
NCBI chr11:69,501,108...69,508,852
Ensembl chr11:69,505,630...69,508,731
G
Shcbp1
Shc SH2-domain binding protein 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of SHCBP1 mRNA
CTD
PMID:20713471
NCBI chr 8:4,785,976...4,829,549
Ensembl chr 8:4,785,976...4,829,567
G
Skic8
SKI8 subunit of superkiller complex
increases expression
EXP
2,4-diaminotoluene results in increased expression of SKIC8 mRNA
CTD
PMID:20713471
NCBI chr 9:54,624,437...54,641,833
Ensembl chr 9:54,622,019...54,641,803
G
Slc16a10
solute carrier family 16 (monocarboxylic acid transporters), member 10
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of SLC16A10 mRNA
CTD
PMID:17070881
NCBI chr10:39,909,528...40,018,262
Ensembl chr10:39,909,528...40,018,254
G
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
increases expression
EXP
2,4-diaminotoluene results in increased expression of SLC16A6 mRNA
CTD
PMID:20713471
NCBI chr11:109,341,681...109,366,428
Ensembl chr11:109,341,681...109,364,424
G
Slfn2
schlafen 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of SLFN2 mRNA
CTD
PMID:20713471
NCBI chr11:82,955,938...82,961,504
Ensembl chr11:82,955,938...82,961,504
G
Slfn9
schlafen 9
increases expression
EXP
2,4-diaminotoluene results in increased expression of SLFN9 mRNA
CTD
PMID:20713471
NCBI chr11:82,865,142...82,883,041
Ensembl chr11:82,869,216...82,882,656
G
Slpi
secretory leukocyte peptidase inhibitor
increases expression
EXP
2,4-diaminotoluene results in increased expression of SLPI mRNA
CTD
PMID:20713471
NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
G
Sod1
superoxide dismutase 1, soluble
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of SOD1 mRNA
CTD
PMID:22016648
NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
G
Spag5
sperm associated antigen 5
increases expression
EXP
2,4-diaminotoluene results in increased expression of SPAG5 mRNA
CTD
PMID:20713471
NCBI chr11:78,192,412...78,213,283
Ensembl chr11:78,192,355...78,213,283
G
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
increases expression
EXP
2,4-diaminotoluene results in increased expression of SPC25 mRNA
CTD
PMID:20713471
NCBI chr 2:69,009,753...69,036,583
Ensembl chr 2:69,024,239...69,036,538
G
Spink1
serine peptidase inhibitor, Kazal type 1
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of SPINK1 mRNA
CTD
PMID:17070881
NCBI chr18:43,861,134...43,870,302
Ensembl chr18:43,861,147...43,870,622
G
Sqle
squalene epoxidase
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of SQLE mRNA
CTD
PMID:20713471
NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
G
Stag1
STAG1 cohesin complex component
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of STAG1 mRNA
CTD
PMID:20713471
NCBI chr 9:100,479,762...100,840,597
Ensembl chr 9:100,479,851...100,841,428
G
Sugct
succinyl-CoA glutarate-CoA transferase
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of SUGCT mRNA
CTD
PMID:17070881
NCBI chr13:17,032,057...17,869,380
Ensembl chr13:17,032,057...17,870,138
G
Sulf2
sulfatase 2
increases expression
ISO
2,4-diaminotoluene results in increased expression of SULF2 mRNA
CTD
PMID:17070881
NCBI chr 2:165,915,819...165,997,603
Ensembl chr 2:165,915,009...165,997,583
G
Sult2a1
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
decreases expression
ISO
2,4-diaminotoluene results in decreased expression of SULT2A1 mRNA
CTD
PMID:17070881
NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
G
Tapbpl
TAP binding protein-like
increases expression
EXP
2,4-diaminotoluene results in increased expression of TAPBPL mRNA
CTD
PMID:20713471
NCBI chr 6:125,200,890...125,208,823
Ensembl chr 6:125,200,896...125,208,823
G
Tbx18
T-box18
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of TBX18 mRNA
CTD
PMID:20713471
NCBI chr 9:87,584,853...87,613,313
Ensembl chr 9:87,584,853...87,613,313
G
Tcp11l2
t-complex 11 (mouse) like 2
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of TCP11L2 mRNA
CTD
PMID:20713471
NCBI chr10:84,412,811...84,450,219
Ensembl chr10:84,412,490...84,450,223
G
Tcstv6a
Tcstv family member 6A
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of TCSTV6A mRNA
CTD
PMID:20713471
NCBI chr13:120,306,880...120,308,226
Ensembl chr13:120,297,542...120,308,106
G
Tecrl
trans-2,3-enoyl-CoA reductase-like
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of TECRL mRNA
CTD
PMID:20713471
NCBI chr 5:83,425,969...83,503,042
Ensembl chr 5:83,425,992...83,503,042
G
Tenm4
teneurin transmembrane protein 4
increases expression
EXP
2,4-diaminotoluene results in increased expression of TENM4 mRNA
CTD
PMID:20713471
NCBI chr 7:95,550,262...96,560,300
Ensembl chr 7:95,820,453...96,560,300
G
Timp2
tissue inhibitor of metalloproteinase 2
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of TIMP2 mRNA
CTD
PMID:22016648
NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566
G
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
increases expression
EXP
2,4-diaminotoluene results in increased expression of TIPARP mRNA
CTD
PMID:20713471
NCBI chr 3:65,435,868...65,462,939
Ensembl chr 3:65,435,831...65,462,939
G
Tk1
thymidine kinase 1
increases expression increases mutagenesis
EXP
2,4-diaminotoluene results in increased expression of TK1 mRNA 2,4-diaminotoluene results in increased mutagenesis of TK1 gene
CTD
PMID:6694660 PMID:20713471
NCBI chr11:117,706,345...117,716,913
Ensembl chr11:117,706,352...117,716,918
G
Tm4sf1
transmembrane 4 superfamily member 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of TM4SF1 mRNA
CTD
PMID:20713471
NCBI chr 3:57,193,038...57,295,150
Ensembl chr 3:57,193,032...57,209,409 Ensembl chr 3:57,193,032...57,209,409
G
Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
increases expression
EXP
2,4-diaminotoluene results in increased expression of TNFRSF9 mRNA
CTD
PMID:20713471
NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
G
Tnnt2
troponin T2, cardiac
increases expression
EXP
2,4-diaminotoluene results in increased expression of TNNT2 mRNA
CTD
PMID:20713471
NCBI chr 1:135,763,933...135,780,006
Ensembl chr 1:135,764,092...135,779,998
G
Top2a
topoisomerase (DNA) II alpha
increases expression
EXP
2,4-diaminotoluene results in increased expression of TOP2A mRNA
CTD
PMID:20713471
NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
G
Tpd52
tumor protein D52
increases expression
EXP
2,4-diaminotoluene results in increased expression of TPD52 mRNA
CTD
PMID:20713471
NCBI chr 3:8,991,590...9,069,824
Ensembl chr 3:8,990,653...9,069,783
G
Trib2
tribbles pseudokinase 2
increases expression
EXP
2,4-diaminotoluene results in increased expression of TRIB2 mRNA
CTD
PMID:20713471
NCBI chr12:15,841,726...15,866,963
Ensembl chr12:15,841,728...15,866,923
G
Trp63
transformation related protein 63
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of TRP63 mRNA
CTD
PMID:20713471
NCBI chr16:25,502,513...25,710,842
Ensembl chr16:25,502,513...25,710,852
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Tspan8
tetraspanin 8
increases expression
EXP
2,4-diaminotoluene results in increased expression of TSPAN8 mRNA
CTD
PMID:20713471
NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798
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Ube2c
ubiquitin-conjugating enzyme E2C
increases expression
EXP
2,4-diaminotoluene results in increased expression of UBE2C mRNA
CTD
PMID:20713471
NCBI chr 2:164,611,849...164,614,822
Ensembl chr 2:164,611,818...164,620,742
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Upp1
uridine phosphorylase 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of UPP1 mRNA
CTD
PMID:20713471
NCBI chr11:9,068,008...9,086,170
Ensembl chr11:9,068,103...9,086,170
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Usp17la
ubiquitin specific peptidase 17-like A
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of USP17LA mRNA
CTD
PMID:20713471
NCBI chr 7:104,506,223...104,511,874
Ensembl chr 7:104,506,216...104,511,874
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Xdh
xanthine dehydrogenase
increases expression
EXP
2,4-diaminotoluene results in increased expression of XDH mRNA
CTD
PMID:20713471
NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191
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Zbp1
Z-DNA binding protein 1
increases expression
EXP
2,4-diaminotoluene results in increased expression of ZBP1 mRNA
CTD
PMID:20713471
NCBI chr 2:173,048,405...173,060,715
Ensembl chr 2:173,048,405...173,060,716
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Zfand2a
zinc finger, AN1-type domain 2A
increases expression
EXP
2,4-diaminotoluene results in increased expression of ZFAND2A mRNA
CTD
PMID:20713471
NCBI chr 5:139,456,971...139,470,246
Ensembl chr 5:139,456,966...139,470,304
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Zfp352
zinc finger protein 352
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of ZFP352 mRNA
CTD
PMID:20713471
NCBI chr 4:90,107,057...90,113,924
Ensembl chr 4:90,107,057...90,113,939
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Zmat3
zinc finger matrin type 3
increases expression
ISO
2,4-diaminotoluene results in increased expression of ZMAT3 mRNA
CTD
PMID:17070881
NCBI chr 3:32,388,941...32,419,814
Ensembl chr 3:32,388,941...32,420,163
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Zscan4c
zinc finger and SCAN domain containing 4C
decreases expression
EXP
2,4-diaminotoluene results in decreased expression of ZSCAN4C mRNA
CTD
PMID:20713471
NCBI chr 7:10,739,672...10,744,474
Ensembl chr 7:10,739,672...10,744,474
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