Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Gtdc1 | Mouse | (-)-alpha-phellandrene | increases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of GTDC1 mRNA | CTD | PMID:25075043 | Gtdc1 | Mouse | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GTDC1 mRNA | CTD | PMID:36331819 | Gtdc1 | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of GTDC1 mRNA | CTD | PMID:22206623 | Gtdc1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of GTDC1 mRNA | CTD | PMID:21570461 | Gtdc1 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GTDC1 mRNA | CTD | PMID:32553695 | Gtdc1 | Mouse | 2,4-diaminotoluene | decreases expression | EXP | | 6480464 | 2 and 4-diaminotoluene results in decreased expression of GTDC1 mRNA | CTD | PMID:20713471 | Gtdc1 | Mouse | 6-propyl-2-thiouracil | decreases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of GTDC1 mRNA | CTD | PMID:30047161 | Gtdc1 | Mouse | 7,12-dimethyltetraphene | decreases expression | EXP | | 6480464 | 9 more ... | CTD | PMID:32553695 | Gtdc1 | Mouse | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of GTDC1 mRNA | CTD | PMID:19770486 | Gtdc1 | Mouse | aflatoxin B1 | decreases methylation | ISO | GTDC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of GTDC1 gene | CTD | PMID:27153756 | Gtdc1 | Mouse | aflatoxin B1 | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of GTDC1 mRNA | CTD | PMID:21641981 and PMID:22100608 | Gtdc1 | Mouse | aflatoxin M1 | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of GTDC1 mRNA | CTD | PMID:30928695 | Gtdc1 | Mouse | alpha-phellandrene | increases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of GTDC1 mRNA | CTD | PMID:25075043 | Gtdc1 | Mouse | amitrole | decreases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of GTDC1 mRNA | CTD | PMID:30047161 | Gtdc1 | Mouse | antirheumatic drug | increases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of GTDC1 mRNA | CTD | PMID:24449571 | Gtdc1 | Mouse | aristolochic acid A | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of GTDC1 mRNA | CTD | PMID:33212167 | Gtdc1 | Mouse | arsenite(3-) | multiple interactions | ISO | GTDC1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to GTDC1 mRNA] | CTD | PMID:32406909 | Gtdc1 | Mouse | atrazine | affects methylation | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of GTDC1 gene | CTD | PMID:28931070 and PMID:35440735 | Gtdc1 | Mouse | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene metabolite results in decreased expression of GTDC1 mRNA and Benzo(a)pyrene results in decreased expression of GTDC1 mRNA | CTD | PMID:19770486 more ... | Gtdc1 | Mouse | benzo[a]pyrene | increases methylation | ISO | GTDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of GTDC1 5' UTR | CTD | PMID:27901495 | Gtdc1 | Mouse | benzo[a]pyrene | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of GTDC1 mRNA | CTD | PMID:20064835 more ... | Gtdc1 | Mouse | benzo[a]pyrene diol epoxide I | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Gtdc1 | Mouse | beta-lapachone | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of GTDC1 mRNA | CTD | PMID:38218311 | Gtdc1 | Mouse | bisphenol A | decreases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of GTDC1 mRNA | CTD | PMID:25181051 | Gtdc1 | Mouse | bisphenol A | decreases methylation | ISO | GTDC1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of GTDC1 gene | CTD | PMID:31601247 | Gtdc1 | Mouse | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GTDC1 mRNA | CTD | PMID:33221593 | Gtdc1 | Mouse | bisphenol A | increases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of GTDC1 mRNA | CTD | PMID:34947998 | Gtdc1 | Mouse | bisphenol A | increases methylation | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of GTDC1 gene | CTD | PMID:28505145 | Gtdc1 | Mouse | butanal | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of GTDC1 mRNA | CTD | PMID:26079696 | Gtdc1 | Mouse | CGP 52608 | multiple interactions | ISO | GTDC1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GTDC1 gene] | CTD | PMID:28238834 | Gtdc1 | Mouse | chlordecone | multiple interactions | EXP | | 6480464 | Chlordecone promotes the reaction [Biomarkers metabolite binds to GTDC1 gene] | CTD | PMID:31084621 | Gtdc1 | Mouse | cisplatin | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of GTDC1 mRNA | CTD | PMID:27392435 | Gtdc1 | Mouse | cisplatin | multiple interactions | ISO | GTDC1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of GTDC1 mRNA | CTD | PMID:27392435 | Gtdc1 | Mouse | copper(II) sulfate | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of GTDC1 mRNA | CTD | PMID:19549813 | Gtdc1 | Mouse | Dibutyl phosphate | affects expression | ISO | GTDC1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of GTDC1 mRNA | CTD | PMID:37042841 | Gtdc1 | Mouse | diethylstilbestrol | increases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Diethylstilbestrol results in increased expression of GTDC1 mRNA | CTD | PMID:21658437 | Gtdc1 | Mouse | dioxygen | increases expression | EXP | | 6480464 | Oxygen deficiency results in increased expression of GTDC1 mRNA | CTD | PMID:22629407 | Gtdc1 | Mouse | dioxygen | multiple interactions | EXP | | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of GTDC1 mRNA] | CTD | PMID:22629407 | Gtdc1 | Mouse | doxorubicin | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of GTDC1 mRNA | CTD | PMID:29803840 | Gtdc1 | Mouse | endosulfan | decreases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of GTDC1 mRNA | CTD | PMID:29391264 | Gtdc1 | Mouse | ethanol | affects expression | EXP | | 6480464 | Ethanol affects the expression of GTDC1 mRNA | CTD | PMID:30319688 | Gtdc1 | Mouse | ethyl methanesulfonate | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of GTDC1 mRNA | CTD | PMID:23649840 | Gtdc1 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of GTDC1 mRNA | CTD | PMID:22206623 | Gtdc1 | Mouse | furan | increases methylation | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | furan results in increased methylation of GTDC1 gene | CTD | PMID:22079235 | Gtdc1 | Mouse | gentamycin | increases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of GTDC1 mRNA | CTD | PMID:33387578 | Gtdc1 | Mouse | indole-3-methanol | multiple interactions | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GTDC1 mRNA | CTD | PMID:22129741 | Gtdc1 | Mouse | methidathion | decreases expression | EXP | | 6480464 | methidathion results in decreased expression of GTDC1 mRNA | CTD | PMID:34813904 | Gtdc1 | Mouse | methimazole | decreases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of GTDC1 mRNA | CTD | PMID:30047161 | Gtdc1 | Mouse | methotrexate | increases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of GTDC1 mRNA | CTD | PMID:24449571 | Gtdc1 | Mouse | methyl methanesulfonate | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of GTDC1 mRNA | CTD | PMID:23649840 | Gtdc1 | Mouse | N,N-diethyl-m-toluamide | multiple interactions | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of GTDC1 gene | CTD | PMID:33148267 | Gtdc1 | Mouse | N-nitrosodiethylamine | multiple interactions | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GTDC1 mRNA | CTD | PMID:22129741 | Gtdc1 | Mouse | O-methyleugenol | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of GTDC1 mRNA | CTD | PMID:32234424 | Gtdc1 | Mouse | oxaliplatin | multiple interactions | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of GTDC1 mRNA | CTD | PMID:25729387 | Gtdc1 | Mouse | perfluorononanoic acid | increases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of GTDC1 mRNA | CTD | PMID:32588087 | Gtdc1 | Mouse | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GTDC1 mRNA | CTD | PMID:36331819 | Gtdc1 | Mouse | permethrin | multiple interactions | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of GTDC1 gene | CTD | PMID:33148267 | Gtdc1 | Mouse | sodium dichromate | affects expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | sodium bichromate affects the expression of GTDC1 mRNA | CTD | PMID:22110744 | Gtdc1 | Mouse | Soman | decreases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Soman results in decreased expression of GTDC1 mRNA | CTD | PMID:19281266 | Gtdc1 | Mouse | sulfadimethoxine | decreases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of GTDC1 mRNA | CTD | PMID:30047161 | Gtdc1 | Mouse | sunitinib | increases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of GTDC1 mRNA | CTD | PMID:31533062 | Gtdc1 | Mouse | thioacetamide | decreases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of GTDC1 mRNA | CTD | PMID:34492290 | Gtdc1 | Mouse | topotecan | multiple interactions | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of GTDC1 mRNA | CTD | PMID:25729387 | Gtdc1 | Mouse | trichloroethene | increases methylation | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased methylation of GTDC1 gene | CTD | PMID:27618143 | Gtdc1 | Mouse | trichostatin A | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of GTDC1 mRNA | CTD | PMID:24935251 | Gtdc1 | Mouse | triptonide | affects expression | EXP | | 6480464 | triptonide affects the expression of GTDC1 mRNA | CTD | PMID:33045310 | Gtdc1 | Mouse | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of GTDC1 mRNA | CTD | PMID:17292431 and PMID:17963808 | Gtdc1 | Mouse | valproic acid | decreases expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of GTDC1 mRNA | CTD | PMID:23179753 more ... | Gtdc1 | Mouse | valproic acid | affects expression | ISO | GTDC1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of GTDC1 mRNA | CTD | PMID:25979313 | Gtdc1 | Mouse | vinclozolin | increases expression | ISO | Gtdc1 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of GTDC1 mRNA | CTD | PMID:23034163 | |