Rad51 (RAD51 recombinase) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Rad51 (RAD51 recombinase) Mus musculus
Analyze
Symbol: Rad51
Name: RAD51 recombinase
RGD ID: 1316728
MGI Page MGI
Description: Enables DNA strand exchange activity; chromatin binding activity; and single-stranded DNA binding activity. Involved in DNA metabolic process. Acts upstream of or within several processes, including DNA metabolic process; cellular response to hydroxyurea; and chromosome organization. Located in chromosome; cytoplasm; and male germ cell nucleus. Is active in site of double-strand break. Is expressed in several structures, including brain; compacted morula; gonad; hemolymphoid system; and paravertebral ganglion. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group R; breast cancer; congenital mirror movement disorder; and ovarian cancer. Orthologous to human RAD51 (RAD51 recombinase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AV304093; DNA repair protein RAD51 homolog 1; Rad; RAD51 homolog A; Rad51a; Re; Reca
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392118,943,295 - 118,966,554 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2118,943,274 - 118,977,926 (+)EnsemblGRCm39 Ensembl
GRCm382119,112,814 - 119,136,073 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,112,793 - 119,147,445 (+)EnsemblGRCm38mm10GRCm38
MGSCv372118,938,553 - 118,961,806 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362118,804,258 - 118,827,511 (+)NCBIMGSCv36mm8
Celera2120,265,474 - 120,286,601 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,4-dioxane  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
3-methylcholanthrene  (EXP)
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid  (ISO)
4-hydroperoxycyclophosphamide  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP)
abexinostat  (ISO)
acetamide  (ISO)
acetylleucyl-leucyl-norleucinal  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amsacrine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
biphenyl-4-amine  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (ISO)
Bisphenol A diglycidyl ether  (EXP)
bortezomib  (ISO)
bromoacetate  (ISO)
bromobenzene  (ISO)
busulfan  (EXP)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
cerium trichloride  (ISO)
chlorambucil  (ISO)
chlordecone  (EXP)
chlorothalonil  (EXP)
choline  (EXP)
chromium(6+)  (ISO)
chrysene  (EXP)
cisplatin  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (ISO)
curcumin  (ISO)
CX-5461  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cypermethrin  (EXP)
cytarabine  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (EXP)
dibenz[a,h]anthracene  (EXP)
dibenzofuran  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (ISO)
diethylstilbestrol  (EXP)
dinaciclib  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
erlotinib hydrochloride  (ISO)
erythromycin estolate  (ISO)
estragole  (ISO)
etoposide  (ISO)
fenthion  (ISO)
flumequine  (EXP)
folic acid  (EXP)
fulvestrant  (ISO)
furan  (ISO)
gallic acid  (ISO)
gefitinib  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
ginsenoside Rg1  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (ISO)
idarubicin  (EXP)
irinotecan  (ISO)
L-methionine  (EXP)
lanthanum trichloride  (ISO)
leflunomide  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (EXP)
lucanthone  (ISO)
mechlorethamine  (EXP)
MeIQx  (EXP)
menadione  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
mitomycin C  (ISO)
myristicin  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N,N-dimethylformamide  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
Nonidet P-40  (ISO)
ochratoxin A  (ISO)
olaparib  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (ISO)
PCB138  (EXP)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
phosphoramide mustard  (ISO)
phytoestrogen  (ISO)
pifithrin-alpha hydrobromide  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
prodigiosin  (ISO)
progesterone  (EXP)
propiconazole  (EXP)
quercetin  (ISO)
quizartinib  (ISO)
resveratrol  (ISO)
romidepsin  (ISO)
rotenone  (ISO)
SB 203580  (ISO)
selenocystine  (ISO)
silicon dioxide  (EXP)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
terbufos  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
tetraphene  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
troglitazone  (ISO)
trovafloxacin  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)
zearalenone  (EXP)
zinc oxide  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to alkaloid  (IMP)
cellular response to camptothecin  (ISO,ISS)
cellular response to cisplatin  (IEA,ISO)
cellular response to gamma radiation  (IEA,ISO)
cellular response to hydroxyurea  (IMP)
cellular response to ionizing radiation  (ISO,ISS)
chromosome organization involved in meiotic cell cycle  (IBA,IMP)
DNA damage response  (ISO,ISS,TAS)
DNA recombinase assembly  (IBA,ISO,ISS)
DNA repair  (TAS)
DNA strand invasion  (IBA)
DNA unwinding involved in DNA replication  (ISO,ISS)
double-strand break repair involved in meiotic recombination  (IDA)
double-strand break repair via homologous recombination  (IDA,IMP,ISO)
interstrand cross-link repair  (ISO,ISS)
meiosis I  (ISO)
meiotic cell cycle  (IDA)
mitotic recombination  (IBA)
mitotic recombination-dependent replication fork processing  (IEA)
positive regulation of DNA ligation  (IEA,ISO)
reciprocal meiotic recombination  (IBA,IDA,TAS)
regulation of DNA damage checkpoint  (NAS)
regulation of double-strand break repair via homologous recombination  (ISO,ISS)
regulation of protein phosphorylation  (IMP)
replication fork processing  (IMP,ISO)
replication-born double-strand break repair via sister chromatid exchange  (IMP)
response to glucoside  (IEA,ISO)
response to organic cyclic compound  (ISO)
response to toxic substance  (IEA,ISO)
response to X-ray  (IEA,ISO)
response to xenobiotic stimulus  (IEA,ISO)
telomere maintenance via recombination  (IGI)
telomere maintenance via telomere lengthening  (IGI)
telomere organization  (IMP)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. Antoniou AC, etal., Am J Hum Genet. 2007 Dec;81(6):1186-200. Epub 2007 Oct 16.
2. Polymorphisms in DNA repair genes and epithelial ovarian cancer risk. Auranen A, etal., Int J Cancer. 2005 Nov 20;117(4):611-8.
3. Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
4. A specific RAD51 haplotype increases breast cancer risk in Jewish non-Ashkenazi high-risk women. Gal I, etal., Eur J Cancer. 2006 May;42(8):1129-34. Epub 2006 Apr 18.
5. Regulation of homologous recombination in eukaryotes. Heyer WD, etal., Annu Rev Genet. 2010;44:113-39. doi: 10.1146/annurev-genet-051710-150955.
6. The RAD51 135 G>C polymorphism modifies breast cancer and ovarian cancer risk in Polish BRCA1 mutation carriers. Jakubowska A, etal., Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):270-5.
7. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
8. BRCA1 shields vascular smooth muscle cells from oxidative stress. Lovren F, etal., J Thorac Cardiovasc Surg. 2014 Jun;147(6):1946-55, 1955.e1. doi: 10.1016/j.jtcvs.2013.09.060. Epub 2013 Nov 13.
9. In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection. Marotta D, etal., Cancer Res. 2011 Feb 1;71(3):779-89. doi: 10.1158/0008-5472.CAN-10-3061. Epub 2011 Jan 25.
10. RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors. Martin RW, etal., Cancer Res. 2007 Oct 15;67(20):9658-65.
11. MGDs mouse GO annotations MGD data from the GO Consortium
12. MGD IEA MGD IEA
13. Genetic instability in the RAD51 and BRCA1 regions in breast cancer. Nowacka-Zawisza M, etal., Cell Mol Biol Lett. 2007;12(2):192-205. Epub 2006 Dec 18.
14. Dinucleotide repeat polymorphisms of RAD51, BRCA1, BRCA2 gene regions in breast cancer. Nowacka-Zawisza M, etal., Pathol Int. 2008 May;58(5):275-81.
15. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. Mouse MP Annotation Import Pipeline RGD automated import pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Disparate impact of butyroyloxymethyl diethylphosphate (AN-7), a histone deacetylase inhibitor, and doxorubicin in mice bearing a mammary tumor. Tarasenko N, etal., PLoS One. 2012;7(2):e31393. doi: 10.1371/journal.pone.0031393. Epub 2012 Feb 23.
21. Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesis. Tryndyak VP, etal., Mol Carcinog. 2007 Mar;46(3):187-97.
22. [Expression of RAD51 and MAX in pancreatic cancer rats]. Yang L, etal., Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Feb;35(2):146-51. doi: 10.3969/j.issn.1672-7347.2010.02.010.
Additional References at PubMed
PMID:7633422   PMID:7774567   PMID:8188269   PMID:8341671   PMID:8358431   PMID:8602360   PMID:8617512   PMID:8628240   PMID:8692798   PMID:8816780   PMID:8943369   PMID:9126738  
PMID:9171369   PMID:9192668   PMID:9311981   PMID:9417871   PMID:9512535   PMID:9655934   PMID:9670959   PMID:9774970   PMID:10209103   PMID:10349636   PMID:10422536   PMID:10809667  
PMID:10922068   PMID:11042159   PMID:11076861   PMID:11477095   PMID:11591653   PMID:11923292   PMID:12091911   PMID:12379650   PMID:12477932   PMID:12485996   PMID:12520002   PMID:12531026  
PMID:12591952   PMID:12687013   PMID:12749858   PMID:12893777   PMID:12913077   PMID:14559999   PMID:14576820   PMID:14610273   PMID:14636569   PMID:14668445   PMID:14736746   PMID:14764457  
PMID:15359272   PMID:15364958   PMID:15475264   PMID:15485900   PMID:15489334   PMID:15750625   PMID:15782199   PMID:15834424   PMID:15897881   PMID:15965906   PMID:16141072   PMID:16141073  
PMID:16420439   PMID:16428451   PMID:17291760   PMID:17599069   PMID:17767921   PMID:17967808   PMID:18003859   PMID:18283110   PMID:18632630   PMID:18694567   PMID:18799693   PMID:18974875  
PMID:18992372   PMID:19112184   PMID:19117011   PMID:19213844   PMID:19735653   PMID:19948482   PMID:20059948   PMID:20169201   PMID:20189471   PMID:20211142   PMID:20484223   PMID:20551173  
PMID:20647542   PMID:20976249   PMID:20979543   PMID:21076401   PMID:21267068   PMID:21276791   PMID:21459848   PMID:21478856   PMID:21637789   PMID:21653319   PMID:21655083   PMID:21677750  
PMID:21743440   PMID:21873635   PMID:21998700   PMID:22156371   PMID:22164254   PMID:22305526   PMID:22388890   PMID:22492707   PMID:22530760   PMID:22560297   PMID:22665067   PMID:22705496  
PMID:22778135   PMID:22922362   PMID:23133398   PMID:23151479   PMID:23341130   PMID:23451117   PMID:23555294   PMID:23969417   PMID:24005329   PMID:24068956   PMID:24108124   PMID:24210700  
PMID:24550317   PMID:24553289   PMID:24583581   PMID:24797475   PMID:24882376   PMID:24886500   PMID:24891606   PMID:24913804   PMID:24943459   PMID:24991985   PMID:25010009   PMID:25463395  
PMID:25488918   PMID:25810472   PMID:26490168   PMID:26742488   PMID:26876348   PMID:27131790   PMID:27225532   PMID:27251002   PMID:27425845   PMID:27739607   PMID:27760146   PMID:27760317  
PMID:28057929   PMID:28199840   PMID:28552778   PMID:28912125   PMID:29125140   PMID:29329290   PMID:29445148   PMID:29447390   PMID:29955025   PMID:30024881   PMID:30188106   PMID:30272023  
PMID:30297419   PMID:30302025   PMID:30668564   PMID:30746471   PMID:30760716   PMID:30783098   PMID:30949703   PMID:31242413   PMID:31358751   PMID:31453335   PMID:31624230   PMID:32029273  
PMID:32094118   PMID:32219340   PMID:32345962   PMID:32463460   PMID:32502153   PMID:32588736   PMID:32610038   PMID:32845237   PMID:32968282   PMID:33110058   PMID:33200984   PMID:33602822  
PMID:33798452   PMID:33864208   PMID:34026442   PMID:34043941   PMID:34059773   PMID:34321999   PMID:34746147   PMID:34819065   PMID:34880491   PMID:35176943   PMID:35292640   PMID:35310947  
PMID:35489071   PMID:35546066   PMID:35671285   PMID:35920200   PMID:35969748   PMID:36058112   PMID:36440627   PMID:36642183   PMID:36718792   PMID:36938872   PMID:37370140   PMID:37439366  
PMID:37563658   PMID:37661798   PMID:37891173   PMID:37973188   PMID:38459011   PMID:38485951  


Genomics

Comparative Map Data
Rad51
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392118,943,295 - 118,966,554 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2118,943,274 - 118,977,926 (+)EnsemblGRCm39 Ensembl
GRCm382119,112,814 - 119,136,073 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,112,793 - 119,147,445 (+)EnsemblGRCm38mm10GRCm38
MGSCv372118,938,553 - 118,961,806 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362118,804,258 - 118,827,511 (+)NCBIMGSCv36mm8
Celera2120,265,474 - 120,286,601 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.92NCBI
RAD51
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381540,694,733 - 40,732,340 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1540,694,774 - 40,732,340 (+)EnsemblGRCh38hg38GRCh38
GRCh371540,987,372 - 41,024,538 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,774,651 - 38,811,648 (+)NCBINCBI36Build 36hg18NCBI36
Build 341538,774,660 - 38,811,646NCBI
Celera1517,755,220 - 17,792,245 (+)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1517,834,870 - 17,872,189 (+)NCBIHuRef
CHM1_11541,107,382 - 41,144,356 (+)NCBICHM1_1
T2T-CHM13v2.01538,500,415 - 38,538,035 (+)NCBIT2T-CHM13v2.0
Rad51
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83126,554,210 - 126,578,888 (+)NCBIGRCr8
mRatBN7.23106,099,753 - 106,125,038 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3106,100,381 - 106,125,035 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3109,773,488 - 109,798,183 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03118,369,034 - 118,393,719 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03116,029,412 - 116,054,104 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03110,918,240 - 110,942,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,918,243 - 110,942,917 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03117,468,402 - 117,493,566 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,625,265 - 105,650,392 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3105,013,953 - 105,038,371 (+)NCBICelera
Cytogenetic Map3q35NCBI
Rad51
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554167,566,686 - 7,590,628 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554167,566,715 - 7,590,628 (+)NCBIChiLan1.0ChiLan1.0
RAD51
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21629,938,330 - 29,973,033 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11534,089,788 - 34,123,970 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01519,638,310 - 19,672,474 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11537,891,061 - 37,925,207 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1537,891,056 - 37,925,207 (+)Ensemblpanpan1.1panPan2
RAD51
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1307,842,540 - 7,877,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl307,842,540 - 7,877,606 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha307,896,289 - 7,931,113 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0307,968,785 - 8,004,039 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl307,968,784 - 8,004,029 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1307,892,599 - 7,927,542 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0307,999,640 - 8,034,564 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0308,128,251 - 8,163,404 (+)NCBIUU_Cfam_GSD_1.0
Rad51
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864086,263,812 - 86,288,764 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364714,114,530 - 4,136,248 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364714,119,020 - 4,136,811 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD51
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1130,586,665 - 130,640,136 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11130,592,414 - 130,640,326 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21145,751,297 - 145,798,501 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAD51
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12642,281,085 - 42,319,394 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2642,279,608 - 42,318,169 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604898,661,431 - 98,701,069 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rad51
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248047,957,253 - 7,983,619 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248047,957,175 - 7,983,078 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2184
Count of miRNA genes:748
Interacting mature miRNAs:932
Transcripts:ENSMUST00000028795, ENSMUST00000110828, ENSMUST00000140939, ENSMUST00000141389, ENSMUST00000143934, ENSMUST00000151406, ENSMUST00000152327, ENSMUST00000154683
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
12904007Cfq7_mconditioned fear QTL 7 (mouse)2118356772125048872Mouse
13506762Tbvq2_mtrabecular bone volume QTL 2 (mouse)2115430481124741920Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1300798Actre3_mactivity response to ethanol 3 (mouse)Not determined2112024987128173821Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
1301415Actre4_mactivity response to ethanol 4 (mouse)Not determined2112024987128173821Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
1558825Aabpr_maberrant activation of B cell proliferation (mouse)Not determined2116033229122207534Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291089974125090104Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse

Markers in Region
AV304093  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382119,135,721 - 119,135,861UniSTSGRCm38
MGSCv372118,961,457 - 118,961,597UniSTSGRCm37
Celera2120,286,252 - 120,286,392UniSTS
Cytogenetic Map2F1UniSTS
cM Map266.8UniSTS
Whitehead/MRC_RH21525.24UniSTS
RH125939  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387116,018,956 - 116,019,166UniSTSGRCm38
GRCm382119,135,744 - 119,135,960UniSTSGRCm38
MGSCv377123,162,470 - 123,162,680UniSTSGRCm37
MGSCv372118,961,480 - 118,961,696UniSTSGRCm37
Celera2120,286,275 - 120,286,491UniSTS
Celera7115,966,033 - 115,966,249UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map2F1UniSTS
cM Map755.0UniSTS
cM Map266.8UniSTS
Rad51  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382119,135,132 - 119,135,316UniSTSGRCm38
MGSCv372118,960,868 - 118,961,052UniSTSGRCm37
Celera2120,285,663 - 120,285,847UniSTS
Cytogenetic Map2F1UniSTS
cM Map266.8UniSTS
Rad51  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2F1UniSTS
cM Map266.8UniSTS
Rad51  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2F1UniSTS
cM Map266.8UniSTS
Rad51  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2F1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_156017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI592821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL772264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D13473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D13803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000028795   ⟹   ENSMUSP00000028795
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,943,288 - 118,967,771 (+)Ensembl
GRCm38.p6 Ensembl2119,112,807 - 119,137,290 (+)Ensembl
Ensembl Acc Id: ENSMUST00000110828
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,943,295 - 118,964,080 (+)Ensembl
GRCm38.p6 Ensembl2119,112,814 - 119,133,599 (+)Ensembl
Ensembl Acc Id: ENSMUST00000140939   ⟹   ENSMUSP00000119444
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,943,274 - 118,954,327 (+)Ensembl
GRCm38.p6 Ensembl2119,112,793 - 119,123,846 (+)Ensembl
Ensembl Acc Id: ENSMUST00000141389
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,949,177 - 118,952,743 (+)Ensembl
GRCm38.p6 Ensembl2119,118,696 - 119,122,262 (+)Ensembl
Ensembl Acc Id: ENSMUST00000143934
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,964,643 - 118,965,689 (+)Ensembl
GRCm38.p6 Ensembl2119,134,162 - 119,135,208 (+)Ensembl
Ensembl Acc Id: ENSMUST00000151406   ⟹   ENSMUSP00000117939
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,954,284 - 118,977,926 (+)Ensembl
GRCm38.p6 Ensembl2119,123,803 - 119,147,445 (+)Ensembl
Ensembl Acc Id: ENSMUST00000152327   ⟹   ENSMUSP00000119101
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,943,298 - 118,967,518 (+)Ensembl
GRCm38.p6 Ensembl2119,112,817 - 119,137,037 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154683
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2118,961,999 - 118,964,936 (+)Ensembl
GRCm38.p6 Ensembl2119,131,518 - 119,134,455 (+)Ensembl
RefSeq Acc Id: NM_011234   ⟹   NP_035364
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392118,943,295 - 118,966,554 (+)NCBI
GRCm382119,112,814 - 119,136,073 (+)NCBI
MGSCv372118,938,553 - 118,961,806 (+)RGD
Celera2120,265,474 - 120,286,601 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_156017
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392118,943,295 - 118,966,554 (+)NCBI
GRCm382119,112,814 - 119,136,073 (+)NCBI
Sequence:
RefSeq Acc Id: NP_035364   ⟸   NM_011234
- UniProtKB: Q3UAY5 (UniProtKB/Swiss-Prot),   Q08297 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000119101   ⟸   ENSMUST00000152327
Ensembl Acc Id: ENSMUSP00000028795   ⟸   ENSMUST00000028795
Ensembl Acc Id: ENSMUSP00000117939   ⟸   ENSMUST00000151406
Ensembl Acc Id: ENSMUSP00000119444   ⟸   ENSMUST00000140939
Protein Domains
HhH   RecA family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q08297-F1-model_v2 AlphaFold Q08297 1-339 view protein structure

Promoters
RGD ID:6832243
Promoter ID:MM_KWN:31210
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000110828,   OTTMUST00000037427,   OTTMUST00000037428,   OTTMUST00000037430
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362118,938,111 - 118,938,611 (+)MPROMDB
RGD ID:6832244
Promoter ID:MM_KWN:31214
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000037433
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362118,959,921 - 118,960,421 (+)MPROMDB
RGD ID:6878326
Promoter ID:EPDNEW_M2614
Type:initiation region
Name:Rad51_1
Description:Mus musculus RAD51 recombinase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382119,112,855 - 119,112,915EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97890 AgrOrtholog
Ensembl Genes ENSMUSG00000027323 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000028795 ENTREZGENE
  ENSMUST00000028795.10 UniProtKB/Swiss-Prot
  ENSMUST00000140939.8 UniProtKB/TrEMBL
  ENSMUST00000151406.2 UniProtKB/TrEMBL
  ENSMUST00000152327.8 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  5' to 3' exonuclease, C-terminal subdomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  DNA_recomb/repair_Rad51 UniProtKB/Swiss-Prot
  DNA_recomb/repair_Rad51_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_recomb/repair_RecA-like UniProtKB/Swiss-Prot
  DNA_repair_Rad51/TF_NusA_a-hlx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RecA_ATP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RecA_monomer-monomer_interface UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19361 UniProtKB/Swiss-Prot
MGD MGI:97890 ENTREZGENE
NCBI Gene 19361 ENTREZGENE
PANTHER DNA REPAIR PROTEIN RAD51 HOMOLOG 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HHH_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rad51 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rad51 PhenoGen
PIRSF Rad51 UniProtKB/Swiss-Prot
PROSITE RECA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECA_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART AAA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47794 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A3KGI2_MOUSE UniProtKB/TrEMBL
  D6RCK1_MOUSE UniProtKB/TrEMBL
  F7AT35_MOUSE UniProtKB/TrEMBL
  Q08297 ENTREZGENE
  Q3UAY5 ENTREZGENE
  RAD51_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3UAY5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Rad51  RAD51 recombinase    RAD51 homolog  Symbol and/or name change 5135510 APPROVED
2012-12-25 Rad51  RAD51 homolog    RAD51 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED