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Gene: Ndc80 (NDC80 kinetochore complex component) Mus musculus
Symbol: Ndc80
Name: NDC80 kinetochore complex component
Description: Predicted to have identical protein binding activity. Predicted to be involved in several processes, including microtubule cytoskeleton organization involved in mitosis; positive regulation of mitotic cell cycle spindle assembly checkpoint; and positive regulation of protein localization to kinetochore. Predicted to localize to the centrosome; kinetochore; and nucleoplasm. Orthologous to human NDC80 (NDC80 kinetochore complex component); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610020P18Rik; AV139730; HEC; HEC1; highly expressed in cancer, rich in leucine heptad repeats; kinetochore associated 2; kinetochore protein Hec1; kinetochore protein NDC80 homolog; kinetochore-associated protein 2; Kntc2; NDC80 homolog, kinetochore complex component
Homo sapiens (human) : NDC80 (NDC80 kinetochore complex component)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ndc80 (NDC80 kinetochore complex component)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ndc80 (NDC80 kinetochore complex component)
Pan paniscus (bonobo/pygmy chimpanzee) : NDC80 (NDC80 kinetochore complex component)
Canis lupus familiaris (dog) : NDC80 (NDC80 kinetochore complex component)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ndc80 (NDC80 kinetochore complex component)
Sus scrofa (pig) : NDC80 (NDC80 kinetochore complex component)
more info ...
Related Pseudogenes: 2700099C18Rik   Gm5357  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1771,496,100 - 71,526,857 (-)Ensembl
GRCm381771,496,100 - 71,526,857 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371771,845,440 - 71,876,197 (-)NCBIGRCm37mm9NCBIm37
MGSCv361771,400,962 - 71,431,714 (-)NCBImm8
Celera1775,767,449 - 75,800,160 (-)NCBICelera
Cytogenetic Map17 E1.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ndc80
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320891
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.