Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gpc1 (glypican 1) Mus musculus
Symbol: Gpc1
Name: glypican 1
Description: Exhibits fibroblast growth factor binding activity and laminin binding activity. Involved in negative regulation of fibroblast growth factor receptor signaling pathway and positive regulation of skeletal muscle cell differentiation. Localizes to the extracellular matrix; membrane raft; and synapse. Is expressed in several structures, including alimentary system; limb; metanephros; musculoskeletal system; and nervous system. Orthologous to human GPC1 (glypican 1); PARTICIPATES IN Hedgehog signaling pathway; glypican signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI462976; glypican-1
Homo sapiens (human) : GPC1 (glypican 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gpc1 (glypican 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpc1 (glypican 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GPC1 (glypican 1)
Canis lupus familiaris (dog) : GPC1 (glypican 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpc1 (glypican 1)
Sus scrofa (pig) : GPC1 (glypican 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl192,831,645 - 92,860,779 (+)Ensembl
GRCm38192,831,645 - 92,860,211 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37194,728,263 - 94,756,773 (+)NCBIGRCm37mm9NCBIm37
MGSCv36194,662,092 - 94,690,602 (+)NCBImm8
Celera195,776,004 - 95,804,554 (+)NCBICelera
Cytogenetic Map1 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gpc1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62145
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.