Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ptx3 (pentraxin related gene) Mus musculus
Symbol: Ptx3
Name: pentraxin related gene
Description: Exhibits (1->3)-beta-D-glucan binding activity. Involved in several processes, including opsonization; ovarian cumulus expansion; and positive regulation of nitric oxide biosynthetic process. Localizes to the extracellular matrix. Is expressed in cochlea; cochlea epithelium; inner ear vestibular component; organ of Corti; and stria vascularis. Orthologous to human PTX3 (pentraxin 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI607804; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; pentraxin-related protein PTX3; TSG-14; tumor necrosis factor-inducible gene 14 protein
Homo sapiens (human) : PTX3 (pentraxin 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptx3 (pentraxin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptx3 (pentraxin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PTX3 (pentraxin 3)
Canis lupus familiaris (dog) : PTX3 (pentraxin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptx3 (pentraxin 3)
Sus scrofa (pig) : PTX3 (pentraxin 3)
Chlorocebus sabaeus (green monkey) : PTX3 (pentraxin 3)
Heterocephalus glaber (naked mole-rat) : Ptx3 (pentraxin 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl366,219,910 - 66,225,805 (+)Ensembl
GRCm38366,219,887 - 66,225,806 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37366,023,809 - 66,029,728 (+)NCBIGRCm37mm9NCBIm37
MGSCv36366,307,812 - 66,313,734 (+)NCBImm8
Celera366,363,920 - 66,369,839 (+)NCBICelera
Cytogenetic Map3 E1NCBI
cM Map330.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ptx3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557644
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.