CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 3,3',4,4',5-pentachlorobiphenyl
Accession: CHEBI:34317
browse the term
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Synonyms: exact_synonym: 3,3',4,4',5-pentachloro-1,1'-biphenyl
related_synonym: 3,4,5,3',4'-Penta coplanar polychlorinated biphenyl; Formula=C12H5Cl5; InChI=1S/C12H5Cl5/c13-8-2-1-6(3-9(8)14)7-4-10(15)12(17)11(16)5-7/h1-5H; InChIKey=REHONNLQRWTIFF-UHFFFAOYSA-N; PCB 126; SMILES=Clc1ccc(cc1Cl)-c1cc(Cl)c(Cl)c(Cl)c1
xref: CAS:57465-28-8; KEGG:C14573
xref_mesh: MESH:C023035
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A2M
alpha-2-macroglobulin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of A2M mRNA
CTD
PMID:19692669
NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
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AACS
acetoacetyl-CoA synthetase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AACS mRNA
CTD
PMID:23196670
NCBI chr12:125,065,435...125,143,316
Ensembl chr12:125,065,434...125,143,333
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AADAC
arylacetamide deacetylase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AADAC mRNA
CTD
PMID:22429928
NCBI chr 3:151,814,116...151,828,488
Ensembl chr 3:151,814,073...151,828,488
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AADAT
aminoadipate aminotransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AADAT mRNA
CTD
PMID:20959002
NCBI chr 4:170,060,222...170,094,292
Ensembl chr 4:170,060,222...170,091,699
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AATK
apoptosis associated tyrosine kinase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AATK mRNA
CTD
PMID:32119087
NCBI chr17:81,117,295...81,166,221
Ensembl chr17:81,110,487...81,166,221
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ABCA1
ATP binding cassette subfamily A member 1
increases expression affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ABCA1 mRNA
CTD
PMID:21703328
NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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ABCC2
ATP binding cassette subfamily C member 2
multiple interactions increases expression decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ABCC2 mRNA
CTD
PMID:15833929 PMID:32119087
NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
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ABCC3
ATP binding cassette subfamily C member 3
multiple interactions increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC3 mRNA
CTD
PMID:15833929 PMID:20959002 PMID:23994337
NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
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ABCC5
ATP binding cassette subfamily C member 5
multiple interactions increases expression decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ABCC5 mRNA
CTD
PMID:15833929 PMID:16260000 PMID:23196670
NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939
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ABCC6
ATP binding cassette subfamily C member 6
multiple interactions increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC6 mRNA
CTD
PMID:15833929
NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522
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ABCD4
ATP binding cassette subfamily D member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ABCD4 mRNA
CTD
PMID:23196670
NCBI chr14:74,285,269...74,302,934
Ensembl chr14:74,285,269...74,303,055
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ABCG1
ATP binding cassette subfamily G member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCG1 mRNA
CTD
PMID:23196670
NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244
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ABCG2
ATP binding cassette subfamily G member 2 (JR blood group)
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCG2 mRNA
CTD
PMID:29947894 PMID:35618242
NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
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ABHD5
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ABHD5 mRNA
CTD
PMID:23196670
NCBI chr 3:43,690,870...43,734,371
Ensembl chr 3:43,690,108...43,734,371
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ACAA2
acetyl-CoA acyltransferase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACAA2 mRNA
CTD
PMID:23196670
NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
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ACACA
acetyl-CoA carboxylase alpha
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of ACACA mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACACA mRNA
CTD
PMID:28973532 PMID:37080397
NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
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ACAT2
acetyl-CoA acetyltransferase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACAT2 mRNA
CTD
PMID:23196670
NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112
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ACKR3
atypical chemokine receptor 3
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACKR3 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 2:236,537,122...236,582,354
Ensembl chr 2:236,567,787...236,582,354
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ACOT7
acyl-CoA thioesterase 7
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACOT7 mRNA
CTD
PMID:23994337
NCBI chr 1:6,264,272...6,393,767
Ensembl chr 1:6,264,269...6,393,767
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ACOX1
acyl-CoA oxidase 1
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACOX1 mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACOX1 mRNA]
CTD
PMID:26396156 PMID:34848246
NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
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ACOX3
acyl-CoA oxidase 3, pristanoyl
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACOX3 mRNA
CTD
PMID:23196670
NCBI chr 4:8,355,305...8,440,723
Ensembl chr 4:8,366,282...8,440,723
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ACP2
acid phosphatase 2, lysosomal
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACP2 mRNA
CTD
PMID:20959002
NCBI chr11:47,239,302...47,248,814
Ensembl chr11:47,239,302...47,248,906
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ACP3
acid phosphatase 3
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ACP3 mRNA
CTD
PMID:20702594
NCBI chr 3:132,317,407...132,368,302
Ensembl chr 3:132,317,369...132,368,302
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ACSBG2
acyl-CoA synthetase bubblegum family member 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACSBG2 mRNA
CTD
PMID:23146750
NCBI chr19:6,135,633...6,193,091
Ensembl chr19:6,135,247...6,193,094
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ACSL3
acyl-CoA synthetase long chain family member 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACSL3 mRNA
CTD
PMID:23196670
NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639
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ACSL5
acyl-CoA synthetase long chain family member 5
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACSL5 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,116...112,428,379
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ACSM2A
acyl-CoA synthetase medium chain family member 2A
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ACSM2 mRNA
CTD
PMID:16984957
NCBI chr16:20,451,521...20,487,669
Ensembl chr16:20,451,461...20,487,669
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ACTA1
actin alpha 1, skeletal muscle
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACTA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACTA1 mRNA
CTD
PMID:19692669 PMID:32119087
NCBI chr 1:229,431,245...229,434,094
Ensembl chr 1:229,430,365...229,434,104
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ACTG2
actin gamma 2, smooth muscle
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACTG2 mRNA
CTD
PMID:32119087
NCBI chr 2:73,893,008...73,919,865
Ensembl chr 2:73,892,314...73,919,865
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ACTL7B
actin like 7B
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACTL7B mRNA
CTD
PMID:23146750
NCBI chr 9:108,854,588...108,855,986
Ensembl chr 9:108,854,588...108,855,986
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ACTN4
actinin alpha 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACTN4 mRNA
CTD
PMID:23196670
NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589
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ACTRT2
actin related protein T2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACTRT2 mRNA
CTD
PMID:23146750
NCBI chr 1:3,021,467...3,022,903
Ensembl chr 1:3,021,467...3,022,903
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ACVR1
activin A receptor type 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACVR1 mRNA
CTD
PMID:23196670
NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,251...157,876,330
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ACY1
aminoacylase 1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACY1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACY1 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr 3:51,983,535...51,989,197
Ensembl chr 3:51,983,340...51,989,197
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ADAM11
ADAM metallopeptidase domain 11
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADAM11 mRNA
CTD
PMID:32119087
NCBI chr17:44,758,988...44,781,846
Ensembl chr17:44,758,988...44,781,846
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ADAM17
ADAM metallopeptidase domain 17
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADAM17 mRNA
CTD
PMID:23196670
NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
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ADAM2
ADAM metallopeptidase domain 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAM2 mRNA
CTD
PMID:23994337
NCBI chr 8:39,743,735...39,838,227
Ensembl chr 8:39,743,735...39,838,227
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ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTS1 mRNA
CTD
PMID:23196670
NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409
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ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTS4 mRNA
CTD
PMID:35618242
NCBI chr 1:161,184,302...161,199,054
Ensembl chr 1:161,184,302...161,199,054
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ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADAMTS5 mRNA
CTD
PMID:23196670
NCBI chr21:26,917,922...26,967,088
Ensembl chr21:26,917,922...26,967,088
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ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif 7
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTS7 mRNA
CTD
PMID:35618242
NCBI chr15:78,759,206...78,811,464
Ensembl chr15:78,759,206...78,811,464
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ADAMTSL2
ADAMTS like 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTSL2 mRNA
CTD
PMID:23146750
NCBI chr 9:133,532,164...133,575,519
Ensembl chr 9:133,532,164...133,575,519
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ADAMTSL3
ADAMTS like 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTSL3 mRNA
CTD
PMID:32119087
NCBI chr15:83,654,123...84,039,842
Ensembl chr15:83,654,088...84,039,842
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ADAMTSL5
ADAMTS like 5
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADAMTSL5 mRNA
CTD
PMID:23146750
NCBI chr19:1,505,022...1,513,019
Ensembl chr19:1,505,022...1,513,604
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ADCY4
adenylate cyclase 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADCY4 mRNA
CTD
PMID:23196670
NCBI chr14:24,318,359...24,335,071
Ensembl chr14:24,318,349...24,335,093
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ADCYAP1R1
ADCYAP receptor type I
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADCYAP1R1 mRNA
CTD
PMID:32119087
NCBI chr 7:31,052,308...31,111,474
Ensembl chr 7:31,052,308...31,111,474
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ADD3
adducin 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADD3 mRNA
CTD
PMID:23196670
NCBI chr10:109,996,373...110,135,565
Ensembl chr10:109,996,368...110,135,565
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ADGRG1
adhesion G protein-coupled receptor G1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADGRG1 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr16:57,619,738...57,665,567
Ensembl chr16:57,610,652...57,665,580
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ADGRG2
adhesion G protein-coupled receptor G2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADGRG2 mRNA
CTD
PMID:19692669
NCBI chr X:18,989,307...19,122,956
Ensembl chr X:18,989,307...19,122,637
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ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADH1B mRNA
CTD
PMID:27055685
NCBI chr 4:99,304,971...99,321,401
Ensembl chr 4:99,304,971...99,321,401
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ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH1 mRNA]
CTD
PMID:34256052
NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746
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ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
decreases expression multiple interactions increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADH4 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH4 mRNA]
CTD
PMID:27055685 PMID:34256052
NCBI chr 4:99,123,658...99,144,297
Ensembl chr 4:99,123,657...99,157,792
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ADH6
alcohol dehydrogenase 6 (class V)
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADH6 mRNA
CTD
PMID:27055685
NCBI chr 4:99,202,639...99,219,246
Ensembl chr 4:99,202,638...99,219,537
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ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADH7 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH7 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 4:99,412,263...99,435,342
Ensembl chr 4:99,412,261...99,435,510
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ADIPOQ
adiponectin, C1Q and collagen domain containing
affects expression multiple interactions decreases expression increases expression increases secretion
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ADIPOQ mRNA 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADIPOQ mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADIPOQ protein 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of ADIPOQ protein
CTD
PMID:21703328 PMID:23146750 PMID:25304490 PMID:29474705 PMID:33026256
NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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ADIPOR1
adiponectin receptor 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ADIPOR1 mRNA
CTD
PMID:37080397
NCBI chr 1:202,940,825...202,958,572
Ensembl chr 1:202,940,826...202,958,572
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ADIPOR2
adiponectin receptor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADIPOR2 mRNA
CTD
PMID:20959002
NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674
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ADM
adrenomedullin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADM mRNA
CTD
PMID:37080397
NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
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ADORA2A
adenosine A2a receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADORA2A mRNA
CTD
PMID:23196670
NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
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ADRA1B
adrenoceptor alpha 1B
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADRA1B mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADRA1B mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 5:159,865,086...159,989,205
Ensembl chr 5:159,865,080...159,973,012
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ADRB2
adrenoceptor beta 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADRB2 mRNA
CTD
PMID:23196670
NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
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ADTRP
androgen dependent TFPI regulating protein
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of ADTRP mRNA
CTD
PMID:30744511
NCBI chr 6:11,713,523...11,778,803
Ensembl chr 6:11,712,054...11,807,046
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AFM
afamin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AFM mRNA
CTD
PMID:20959002
NCBI chr 4:73,481,745...73,504,001
Ensembl chr 4:73,481,745...73,504,001
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AFP
alpha fetoprotein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AFP mRNA
CTD
PMID:20959002
NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
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AGTR1
angiotensin II receptor type 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AGTR1 mRNA
CTD
PMID:14962509
NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
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AHI1
Abelson helper integration site 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHI1 mRNA
CTD
PMID:23196670
NCBI chr 6:135,283,532...135,497,740
Ensembl chr 6:135,283,407...135,498,434
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AHNAK
AHNAK nucleoprotein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AHNAK mRNA
CTD
PMID:19692669
NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235
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AHNAK2
AHNAK nucleoprotein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AHNAK2 mRNA
CTD
PMID:32119087
NCBI chr14:104,937,253...104,978,374
Ensembl chr14:104,937,244...104,978,374
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AHR
aryl hydrocarbon receptor
affects binding multiple interactions decreases expression affects response to substance increases activity increases expression affects expression decreases response to substance increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein 3,4,5,3',4'-pentachlorobiphenyl binds to and results in increased activity of AHR protein; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [6,2',4'-trimethoxyflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; AHR protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; Oxygen deficiency affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of AHR protein] 3,4,5,3',4'-pentachlorobiphenyl binds to and affects the localization of AHR protein; 3,4,5,3',4'-pentachlorobiphenyl binds to and results in increased activity of AHR protein; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of AHR mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]; [2,3,7,8-tetrachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of AHR protein; [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC2 mRNA; [3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC3 mRNA; [3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC5 mRNA; [3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC6 mRNA; [3,4,5,3',4'-pentachlorobiphenyl binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] results in increased expression of AHR mRNA; [AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AHR mRNA] AHR mRNA affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl binds to and results in increased activity of AHR protein]; 3,4,5,3',4'-pentachlorobiphenyl binds to and results in increased activity of AHR protein; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of CCL11 mRNA; [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of CCL22 mRNA; [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of IL11 mRNA; [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in increased secretion of LHB protein; AHR affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GGT1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPX1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH4 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALAD mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH1A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX15 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX5 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AOC1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARNT mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CES2C mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHST1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP17A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP19A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP27B1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B3 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C13 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C6 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C7 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2E1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP3A23-3A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FBP1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GCKR mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX5 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTP1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HK2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B3 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPO mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MARCKS mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MPO mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MTHFR mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOS2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKLR mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRD5A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XDH mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACOX1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREM mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMGCS2 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PC mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PYGL mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A2 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPARA mRNA]; AHR protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Selenic Acid deficiency inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR mRNA]; Selenic Acid inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of AHR mRNA AHR gene mutant form results in decreased susceptibility to 3,4,5,3',4'-pentachlorobiphenyl AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl; AHR protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl 3,3',4,4',5-pentachlorobiphenyl, PCB-126, increases expression of mRNA in rat liver
CTD RGD
PMID:10448124 PMID:11752103 PMID:12628580 PMID:12850102 PMID:15071172 PMID:15352264 PMID:15371557 PMID:15598615 PMID:15833929 PMID:15908097 PMID:15919853 PMID:15990133 PMID:16049271 PMID:16489053 PMID:16705413 PMID:18835618 PMID:19447902 PMID:19692669 PMID:20435555 PMID:20634293 PMID:20728228 PMID:20961953 PMID:21292640 PMID:21775728 PMID:21781905 PMID:21865291 PMID:22262711 PMID:22266287 PMID:22521833 PMID:23644946 PMID:24355420 PMID:24378064 PMID:24812009 PMID:24950391 PMID:25530946 PMID:25654323 PMID:26006071 PMID:26396156 PMID:28284859 PMID:30312631 PMID:31563530 PMID:32119087 PMID:34256052 PMID:34848246 PMID:37080397 PMID:23644946 More...
RGD:401794573
NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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AHRR
aryl hydrocarbon receptor repressor
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHRR mRNA
CTD
PMID:21703328 PMID:23146750 PMID:23196670 PMID:29738842 PMID:31563530 PMID:32119087 More...
NCBI chr 5:321,714...438,285
Ensembl chr 5:321,714...438,291
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AHSP
alpha hemoglobin stabilizing protein
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of AHSP mRNA
CTD
PMID:30744511
NCBI chr16:31,527,900...31,528,803
Ensembl chr16:31,527,900...31,528,803
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AK3
adenylate kinase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AK3 mRNA
CTD
PMID:23196670
NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043
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AKAP12
A-kinase anchoring protein 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AKAP12 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 6:151,239,967...151,358,559
Ensembl chr 6:151,239,967...151,358,559
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AKAP17A
A-kinase anchoring protein 17A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AKAP17B mRNA
CTD
PMID:32119087
NCBI chr X:1,591,604...1,602,520 NCBI chr Y:1,591,604...1,602,520
Ensembl chr Y:1,591,604...1,602,520 Ensembl chr X:1,591,604...1,602,520
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AKAP5
A-kinase anchoring protein 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AKAP5 mRNA
CTD
PMID:23196670
NCBI chr14:64,465,499...64,474,503
Ensembl chr14:64,465,499...64,474,503
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AKR1C1
aldo-keto reductase family 1 member C1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of AKR1C1 mRNA
CTD
PMID:30744511
NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283
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AKR1C2
aldo-keto reductase family 1 member C2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of AKR1C2 mRNA
CTD
PMID:30744511
NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031
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AKR1C8
aldo-keto reductase family 1 member C8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AKR1C15 mRNA
CTD
PMID:32119087
NCBI chr10:5,115,813...5,185,150
Ensembl chr10:5,153,920...5,185,187
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AKR1D1
aldo-keto reductase family 1 member D1
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AKR1D1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AKR1D1 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr 7:138,076,459...138,118,305
Ensembl chr 7:138,002,324...138,118,305
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AKR7A3
aldo-keto reductase family 7 member A3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AKR7A3 mRNA
CTD
PMID:20959002
NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770
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AKT1
AKT serine/threonine kinase 1
affects expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of AKT1 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in increased phosphorylation of AKT1 protein]
CTD
PMID:21703328 PMID:24709675
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
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ALAD
aminolevulinate dehydratase
decreases expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALAD mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALAD mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALAD mRNA]
CTD
PMID:20959002 PMID:34256052
NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
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ALAS1
5'-aminolevulinate synthase 1
multiple interactions increases expression affects expression decreases expression
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ALAS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALAS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ALAS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALAS1 mRNA
CTD
PMID:16984957 PMID:19692669 PMID:20959002 PMID:21703328
NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327
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ALAS2
5'-aminolevulinate synthase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALAS2 mRNA
CTD
PMID:20959002
NCBI chr X:55,009,055...55,030,977
Ensembl chr X:55,009,055...55,030,977
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ALB
albumin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALB mRNA
CTD
PMID:23994337
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
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ALCAM
activated leukocyte cell adhesion molecule
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ALCAM mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALCAM mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 3:105,366,909...105,576,900
Ensembl chr 3:105,366,909...105,576,900
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ALDH1A1
aldehyde dehydrogenase 1 family member A1
decreases expression multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDH1A1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH1A1 mRNA]
CTD
PMID:19692669 PMID:34256052
NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
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ALDH1A3
aldehyde dehydrogenase 1 family member A3
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDH1A3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH1A3 mRNA
CTD
PMID:23196670 PMID:29947894 PMID:32119087
NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,877,714...100,916,626
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ALDH2
aldehyde dehydrogenase 2 family member
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH2 mRNA
CTD
PMID:19692669
NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
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ALDH3A1
aldehyde dehydrogenase 3 family member A1
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH3A1 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:23196670 PMID:23994337 PMID:29738842 PMID:32119087 More...
NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943
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ALDH3B1
aldehyde dehydrogenase 3 family member B1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDH3B1 mRNA
CTD
PMID:23196670
NCBI chr11:68,008,547...68,029,276
Ensembl chr11:68,008,578...68,029,282
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ALDOB
aldolase, fructose-bisphosphate B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDOB mRNA
CTD
PMID:19692669
NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664
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ALDOC
aldolase, fructose-bisphosphate C
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDOC mRNA
CTD
PMID:23196670
NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948
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ALOX15
arachidonate 15-lipoxygenase
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX15 mRNA]
CTD
PMID:34256052
NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
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ALOX5
arachidonate 5-lipoxygenase
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX5 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX5 mRNA]
CTD
PMID:34256052
NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
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ALPL
alkaline phosphatase, biomineralization associated
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALPL mRNA
CTD
PMID:23196670
NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
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AMBP
alpha-1-microglobulin/bikunin precursor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AMBP mRNA
CTD
PMID:19692669
NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328
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AMH
anti-Mullerian hormone
decreases secretion
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of AMH protein
CTD
PMID:34256052
NCBI chr19:2,249,323...2,252,073
Ensembl chr19:2,249,309...2,252,073
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AMPH
amphiphysin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AMPH mRNA
CTD
PMID:23196670
NCBI chr 7:38,383,704...38,631,373
Ensembl chr 7:38,383,704...38,631,420
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ANGPTL2
angiopoietin like 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ANGPTL2 mRNA
CTD
PMID:23196670
NCBI chr 9:127,087,348...127,122,635
Ensembl chr 9:127,087,348...127,122,635
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ANGPTL4
angiopoietin like 4
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANGPTL4 mRNA
CTD
PMID:35618242
NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370
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ANGPTL8
angiopoietin like 8
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of ANGPTL8 mRNA]
CTD
PMID:30312631
NCBI chr19:11,239,619...11,241,943
Ensembl chr19:11,237,502...11,241,943
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ANKH
ANKH inorganic pyrophosphate transport regulator
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ANK mRNA
CTD
PMID:23196670
NCBI chr 5:14,704,800...14,871,778
Ensembl chr 5:14,704,800...14,871,778
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ANP32E
acidic nuclear phosphoprotein 32 family member E
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANP32E mRNA
CTD
PMID:23196670
NCBI chr 1:150,218,417...150,236,112
Ensembl chr 1:150,218,417...150,236,156
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ANPEP
alanyl aminopeptidase, membrane
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANPEP mRNA
CTD
PMID:35618242
NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401
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ANXA2
annexin A2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANXA2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883
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ANXA4
annexin A4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ANXA4 mRNA
CTD
PMID:23994337
NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112
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ANXA5
annexin A5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANXA5 mRNA
CTD
PMID:20959002
NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
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ANXA8
annexin A8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANXA8 mRNA
CTD
PMID:32119087
NCBI chr10:47,467,993...47,991,796
Ensembl chr10:47,460,162...47,484,158
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AOC1
amine oxidase copper containing 1
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AOC1 mRNA]
CTD
PMID:34256052
NCBI chr 7:150,852,120...150,861,504
Ensembl chr 7:150,824,627...150,861,504
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AOC2
amine oxidase copper containing 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AOC2 mRNA
CTD
PMID:23146750
NCBI chr17:42,844,580...42,850,707
Ensembl chr17:42,844,580...42,850,707
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AOPEP
aminopeptidase O (putative)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AOPEP mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 9:94,726,699...95,150,224
Ensembl chr 9:94,726,604...95,151,793
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AOX1
aldehyde oxidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AOX1 mRNA
CTD
PMID:23196670
NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064
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AP1S1
adaptor related protein complex 1 subunit sigma 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AP1S1 mRNA
CTD
PMID:23994337
NCBI chr 7:101,154,476...101,161,276
Ensembl chr 7:101,154,456...101,161,596
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APCS
amyloid P component, serum
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APCS mRNA
CTD
PMID:19692669
NCBI chr 1:159,587,826...159,588,865
Ensembl chr 1:159,587,826...159,588,865
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APLN
apelin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APLN mRNA
CTD
PMID:23196670
NCBI chr X:129,645,259...129,654,956
Ensembl chr X:129,645,259...129,654,956
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APLNR
apelin receptor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of APLNR mRNA
CTD
PMID:32119087
NCBI chr11:57,233,591...57,237,250
Ensembl chr11:57,233,577...57,237,250
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APOA1
apolipoprotein A1
increases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of APOA1 mRNA 3,3',4,4',5-pentachlorobiphenyl, PCB-126, increases expression of mRNA in rat liver
CTD RGD
PMID:23644946 PMID:23644946
RGD:401794573
NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
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APOA4
apolipoprotein A4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APOA4 mRNA
CTD
PMID:20959002
NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
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APOB
apolipoprotein B
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of APOB mRNA
CTD
PMID:28973532
NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
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APOE
apolipoprotein E
decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APOE mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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APOL5
apolipoprotein L5
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APOL5 mRNA
CTD
PMID:23146750
NCBI chr22:35,708,424...35,729,483
Ensembl chr22:35,717,872...35,729,483
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APOM
apolipoprotein M
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APOM mRNA
CTD
PMID:20959002
NCBI chr 6:31,652,404...31,658,210
Ensembl chr 6:31,652,416...31,658,210
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APRT
adenine phosphoribosyltransferase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of APRT mRNA
CTD
PMID:23994337
NCBI chr16:88,809,339...88,811,928
Ensembl chr16:88,809,339...88,811,937
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APTX
aprataxin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of APTX mRNA
CTD
PMID:23994337
NCBI chr 9:32,972,616...33,025,120
Ensembl chr 9:32,886,601...33,025,130
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AQP1
aquaporin 1 (Colton blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AQP1 mRNA
CTD
PMID:23196670
NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
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AR
androgen receptor
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; [aroclor 1260 co-treated with Chlorodiphenyl (54% Chlorine) co-treated with 2,4,4'-trichlorobiphenyl co-treated with 2,4,2',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,3',4'-tetrachlorobiphenyl] inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]
CTD
PMID:18324785 PMID:21295777 PMID:21357386 PMID:26022396
NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
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AREG
amphiregulin
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AREG mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
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ARG1
arginase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ARG1 mRNA
CTD
PMID:23196670
NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
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ARHGAP20
Rho GTPase activating protein 20
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ARHGAP20 mRNA
CTD
PMID:23196670
NCBI chr11:110,577,043...110,713,189
Ensembl chr11:110,577,042...110,713,189
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ARHGAP29
Rho GTPase activating protein 29
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ARHGAP29 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARHGAP29 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 1:94,168,905...94,314,592
Ensembl chr 1:94,148,988...94,275,068
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ARHGEF40
Rho guanine nucleotide exchange factor 40
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARHGEF40 mRNA
CTD
PMID:19692669
NCBI chr14:21,061,264...21,090,248
Ensembl chr14:21,070,273...21,090,248
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ARL4C
ADP ribosylation factor like GTPase 4C
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARL4C mRNA
CTD
PMID:29947894
NCBI chr 2:234,493,041...234,497,081
Ensembl chr 2:234,493,041...234,497,081
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ARNT
aryl hydrocarbon receptor nuclear translocator
multiple interactions increases expression affects expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARNT mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ARNT mRNA
CTD
PMID:34256052 PMID:37080397
NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708
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ARNT2
aryl hydrocarbon receptor nuclear translocator 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ARNT2 mRNA
CTD
PMID:23146750
NCBI chr15:80,404,382...80,597,933
Ensembl chr15:80,404,350...80,597,933
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ARTN
artemin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARTN mRNA
CTD
PMID:32119087
NCBI chr 1:43,933,801...43,937,240
Ensembl chr 1:43,933,320...43,937,240
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AS3MT
arsenite methyltransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AS3MT mRNA
CTD
PMID:32119087
NCBI chr10:102,869,470...102,901,899
Ensembl chr10:102,869,470...102,901,899
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ASB16
ankyrin repeat and SOCS box containing 16
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ASB16 mRNA
CTD
PMID:23196670
NCBI chr17:44,170,704...44,179,084
Ensembl chr17:44,170,447...44,179,084
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ASCL5
achaete-scute family bHLH transcription factor 5
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of ASCL5 mRNA
CTD
PMID:30744511
NCBI chr 1:201,113,943...201,127,184
Ensembl chr 1:201,113,943...201,127,184
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ASGR1
asialoglycoprotein receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ASGR1 mRNA
CTD
PMID:23196670
NCBI chr17:7,173,431...7,179,370
Ensembl chr17:7,173,431...7,179,564
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ASPG
asparaginase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ASPG mRNA
CTD
PMID:20959002
NCBI chr14:104,085,700...104,115,582
Ensembl chr14:104,085,686...104,115,582
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ATF3
activating transcription factor 3
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATF3 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
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ATF6
activating transcription factor 6
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ATF6 mRNA
CTD
PMID:37080397
NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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ATG7
autophagy related 7
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ATG7 mRNA
CTD
PMID:37080397
NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
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ATOSB
atos homolog B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATOSB mRNA
CTD
PMID:23994337
NCBI chr 9:35,104,117...35,116,380
Ensembl chr 9:35,104,112...35,116,341
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ATP1B2
ATPase Na+/K+ transporting subunit beta 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ATP1B2 mRNA
CTD
PMID:23196670
NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
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ATP1B3
ATPase Na+/K+ transporting subunit beta 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATP1B3 mRNA
CTD
PMID:23994337
NCBI chr 3:141,876,643...141,926,549
Ensembl chr 3:141,876,124...141,926,549
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ATP2B1
ATPase plasma membrane Ca2+ transporting 1
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in decreased expression of ATP2B1 mRNA
CTD
PMID:31820026
NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366
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ATP2B4
ATPase plasma membrane Ca2+ transporting 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ATP2B4 mRNA
CTD
PMID:23196670
NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081
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ATP2C1
ATPase secretory pathway Ca2+ transporting 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATP2C1 mRNA
CTD
PMID:23196670
NCBI chr 3:130,850,595...131,016,712
Ensembl chr 3:130,850,595...131,016,712
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ATP5IF1
ATP synthase inhibitory factor subunit 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATP5IF1 mRNA
CTD
PMID:23196670
NCBI chr 1:28,236,124...28,238,100
Ensembl chr 1:28,236,109...28,246,906
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ATP6V0E2
ATPase H+ transporting V0 subunit e2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATP6V0E2 mRNA
CTD
PMID:19692669
NCBI chr 7:149,872,964...149,880,713
Ensembl chr 7:149,872,968...149,891,204
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AUP1
AUP1 lipid droplet regulating VLDL assembly factor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AUP1 mRNA
CTD
PMID:23994337
NCBI chr 2:74,526,652...74,529,706
Ensembl chr 2:74,526,645...74,529,760
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AURKA
aurora kinase A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AURKA mRNA
CTD
PMID:23196670
NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337
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AURKB
aurora kinase B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AURKB mRNA
CTD
PMID:23196670
NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600
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AXIN2
axin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AXIN2 mRNA
CTD
PMID:23196670
NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648
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AXL
AXL receptor tyrosine kinase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AXL mRNA
CTD
PMID:23196670
NCBI chr19:41,219,223...41,261,766
Ensembl chr19:41,219,223...41,261,766
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B2M
beta-2-microglobulin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of B2M mRNA
CTD
PMID:37080397
NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
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B4GALNT1
beta-1,4-N-acetyl-galactosaminyltransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of B4GALNT1 mRNA
CTD
PMID:20959002
NCBI chr12:57,623,409...57,633,201
Ensembl chr12:57,623,409...57,633,239
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B4GALT4
beta-1,4-galactosyltransferase 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of B4GALT4 mRNA
CTD
PMID:23196670
NCBI chr 3:119,211,742...119,240,878
Ensembl chr 3:119,211,732...119,240,946
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BACE2
beta-secretase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BACE2 mRNA
CTD
PMID:23196670
NCBI chr21:41,168,160...41,282,530
Ensembl chr21:41,167,801...41,282,530
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BACH2
BTB domain and CNC homolog 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BACH2 mRNA
CTD
PMID:32119087
NCBI chr 6:89,926,528...90,296,843
Ensembl chr 6:89,926,528...90,296,843
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BANF1
BAF nuclear assembly factor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BANF1 mRNA
CTD
PMID:23994337
NCBI chr11:66,002,079...66,004,149
Ensembl chr11:66,002,228...66,004,149
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BARD1
BRCA1 associated RING domain 1
increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BARD1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BARD1 mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr 2:214,725,646...214,809,683
Ensembl chr 2:214,725,646...214,809,683
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BAX
BCL2 associated X, apoptosis regulator
affects expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of BAX mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BAX mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BAX protein
CTD
PMID:21703328 PMID:31563530 PMID:37080397
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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BBOF1
basal body orientation factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BBOF1 mRNA
CTD
PMID:32119087
NCBI chr14:74,019,349...74,082,864
Ensembl chr14:74,019,349...74,082,863
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BBS2
Bardet-Biedl syndrome 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BBS2 mRNA
CTD
PMID:23196670
NCBI chr16:56,470,403...56,520,024
Ensembl chr16:56,465,640...56,582,667
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BCAM
basal cell adhesion molecule (Lutheran blood group)
decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BCAM mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr19:44,809,059...44,821,421
Ensembl chr19:44,809,071...44,821,421
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BCAR1
BCAR1 scaffold protein, Cas family member
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BCAR1 mRNA
CTD
PMID:23196670
NCBI chr16:75,228,181...75,268,007
Ensembl chr16:75,228,181...75,268,053
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BCAT1
branched chain amino acid transaminase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BCAT1 mRNA
CTD
PMID:23196670
NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101
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BCL2
BCL2 apoptosis regulator
multiple interactions decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BCL2 protein
CTD
PMID:20840854 PMID:31563530
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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BCL2L11
BCL2 like 11
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BCL2L11 mRNA
CTD
PMID:23196670
NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444
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BDH1
3-hydroxybutyrate dehydrogenase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BDH1 mRNA
CTD
PMID:23196670
NCBI chr 3:197,509,783...197,573,343
Ensembl chr 3:197,509,783...197,573,323
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BEX3
brain expressed X-linked 3
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BEX3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BEX3 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr X:103,376,323...103,378,164
Ensembl chr X:103,376,395...103,378,164
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BGLAP
bone gamma-carboxyglutamate protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BGLAP protein
CTD
PMID:31820026
NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
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BHLHE40
basic helix-loop-helix family member e40
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BHLHE40 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BHLHE40 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323
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BHLHE41
basic helix-loop-helix family member e41
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BHLHE41 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr12:26,120,030...26,125,037
Ensembl chr12:26,120,030...26,125,037
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BLOC1S2
biogenesis of lysosomal organelles complex 1 subunit 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BLOC1S2 mRNA
CTD
PMID:32119087
NCBI chr10:100,273,278...100,286,680
Ensembl chr10:100,273,280...100,286,680
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BLVRB
biliverdin reductase B
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of BLVRB protein
CTD
PMID:23457121
NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764
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BMAL1
basic helix-loop-helix ARNT like 1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BMAL1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARNTL mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266
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BMP2
bone morphogenetic protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BMP2 mRNA
CTD
PMID:34256052
NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246
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BMP4
bone morphogenetic protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BMP4 mRNA
CTD
PMID:23196670
NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
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BMP6
bone morphogenetic protein 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BMP6 mRNA
CTD
PMID:23196670
NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
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BORA
BORA aurora kinase A activator
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BORA mRNA
CTD
PMID:23196670
NCBI chr13:72,727,923...72,756,196
Ensembl chr13:72,727,749...72,756,198
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BRCA1
BRCA1 DNA repair associated
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BRCA1 mRNA
CTD
PMID:23196670
NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245
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BRINP1
BMP/retinoic acid inducible neural specific 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BRINP1 mRNA
CTD
PMID:23196670
NCBI chr 9:119,166,629...119,369,435
Ensembl chr 9:119,153,458...119,369,435
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BTG2
BTG anti-proliferation factor 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BTG2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
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BTNL9
butyrophilin like 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BTNL9 mRNA
CTD
PMID:32119087
NCBI chr 5:181,040,266...181,061,521
Ensembl chr 5:181,040,225...181,061,521
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C16orf89
chromosome 16 open reading frame 89
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C10H16ORF89 mRNA
CTD
PMID:32119087
NCBI chr16:5,042,772...5,065,956
Ensembl chr16:5,044,122...5,066,110
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C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1GALT1 mRNA
CTD
PMID:23196670
NCBI chr 7:7,157,377...7,248,616
Ensembl chr 7:7,156,934...7,248,616
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C1QA
complement C1q A chain
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1QA mRNA
CTD
PMID:23146750
NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678
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C1QB
complement C1q B chain
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1QB mRNA
CTD
PMID:23146750
NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637
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C1QC
complement C1q C chain
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of C1QC mRNA
CTD
PMID:23196670
NCBI chr 1:22,643,633...22,648,108
Ensembl chr 1:22,643,014...22,648,110
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C1QTNF5
C1q and TNF related 5
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1QTNF5 mRNA
CTD
PMID:23146750
NCBI chr11:119,338,942...119,346,705
Ensembl chr11:119,338,942...119,340,940
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C1S
complement C1s
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1S mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of C1S mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr12:7,060,718...7,071,032
Ensembl chr12:6,988,259...7,071,032
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C3
complement C3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C3 mRNA
CTD
PMID:23196670
NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
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C4A
complement C4A (Chido/Rodgers blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C4A mRNA
CTD
PMID:23196670
NCBI chr 6:31,982,057...32,002,681
Ensembl chr 6:31,982,057...32,002,681
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CA2
carbonic anhydrase 2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CA2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CA2 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
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CA3
carbonic anhydrase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CA3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAR3 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040
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CA5B
carbonic anhydrase 5B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CA5B mRNA
CTD
PMID:23196670
NCBI chr X:15,738,270...15,788,411
Ensembl chr X:15,688,830...15,788,411
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CA8
carbonic anhydrase 8
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CAR8 mRNA
CTD
PMID:20702594
NCBI chr 8:60,185,412...60,281,400
Ensembl chr 8:60,185,412...60,281,400
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CACNB2
calcium voltage-gated channel auxiliary subunit beta 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CACNB2 mRNA
CTD
PMID:23196670
NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557
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CADM1
cell adhesion molecule 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CADM1 mRNA
CTD
PMID:23196670
NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957
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CADPS
calcium dependent secretion activator
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CADPS mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CADPS mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 3:62,398,348...62,875,416
Ensembl chr 3:62,398,346...62,875,416
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CADPS2
calcium dependent secretion activator 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CADPS2 mRNA
CTD
PMID:32119087
NCBI chr 7:122,318,411...122,886,460
Ensembl chr 7:122,318,411...122,886,759
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CALCOCO1
calcium binding and coiled-coil domain 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CALCOCO1 mRNA
CTD
PMID:23196670
NCBI chr12:53,708,517...53,727,452
Ensembl chr12:53,708,517...53,727,745
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CALD1
caldesmon 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CALD1 mRNA
CTD
PMID:23196670
NCBI chr 7:134,745,467...134,970,729
Ensembl chr 7:134,744,252...134,970,729
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CALHM2
calcium homeostasis modulator family member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CALHM2 mRNA
CTD
PMID:23196670
NCBI chr10:103,446,786...103,452,370
Ensembl chr10:103,446,786...103,452,402
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CAMK1
calcium/calmodulin dependent protein kinase I
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAMK1 mRNA
CTD
PMID:32119087
NCBI chr 3:9,757,347...9,769,947
Ensembl chr 3:9,757,347...9,769,992
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CAMK1G
calcium/calmodulin dependent protein kinase IG
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAMK1G mRNA
CTD
PMID:23196670
NCBI chr 1:209,583,714...209,613,939
Ensembl chr 1:209,583,714...209,613,939
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CAMK2N1
calcium/calmodulin dependent protein kinase II inhibitor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAMK2N1 mRNA
CTD
PMID:32119087
NCBI chr 1:20,482,391...20,486,210
Ensembl chr 1:20,482,391...20,486,210
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CAP2
cyclase associated actin cytoskeleton regulatory protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAP2 mRNA
CTD
PMID:20959002
NCBI chr 6:17,393,595...17,557,780
Ensembl chr 6:17,393,595...17,557,780
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CAPN13
calpain 13
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAPN13 mRNA
CTD
PMID:32119087
NCBI chr 2:30,722,771...30,807,446
Ensembl chr 2:30,722,771...30,820,542
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CAPN8
calpain 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAPN8 mRNA
CTD
PMID:23196670
NCBI chr 1:223,541,616...223,665,701
Ensembl chr 1:223,538,007...223,665,723
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CARMIL1
capping protein regulator and myosin 1 linker 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CARMIL1 mRNA
CTD
PMID:20702594
NCBI chr 6:25,279,374...25,620,530
Ensembl chr 6:25,279,078...25,620,530
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CASP12
caspase 12 (gene/pseudogene)
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of CASP12 mRNA
CTD
PMID:30744511
NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670
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CASP3
caspase 3
increases activity increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CASP3 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CASP3 protein
CTD
PMID:19022367 PMID:31563530
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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CASP8
caspase 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CASP8 protein
CTD
PMID:31563530
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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CASP9
caspase 9
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CASP9 protein
CTD
PMID:31563530
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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CAT
catalase
multiple interactions decreases activity increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of CAT mRNA; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of CAT protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAT mRNA
CTD
PMID:24378064 PMID:37080397 PMID:37598416
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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CAV1
caveolin 1
multiple interactions decreases expression
ISO EXP
CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein]; CAV1 gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 gene mutant form promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 protein]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAV mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of FYN protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of KEAP1 protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased phosphorylation of PRKCD protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in increased phosphorylation of AKT1 protein]
CTD
PMID:19265715 PMID:20406653 PMID:23196670 PMID:24709675
NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
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CAVIN2
caveolae associated protein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAVIN2 mRNA
CTD
PMID:23196670
NCBI chr 2:191,834,310...191,847,088
Ensembl chr 2:191,834,310...191,847,088
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CAVIN3
caveolae associated protein 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAVIN3 mRNA
CTD
PMID:23196670
NCBI chr11:6,318,946...6,320,501
Ensembl chr11:6,318,946...6,320,532
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CBR1
carbonyl reductase 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CBR1 mRNA
CTD
PMID:20702594
NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
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CBR3
carbonyl reductase 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CBR3 mRNA
CTD
PMID:32119087
NCBI chr21:36,135,079...36,146,562
Ensembl chr21:36,135,079...36,146,562
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CBX7
chromobox 7
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CBX7 mRNA
CTD
PMID:32119087
NCBI chr22:39,130,772...39,152,680
Ensembl chr22:39,120,167...39,152,680
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CC2D1B
coiled-coil and C2 domain containing 1B
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CC2D1B mRNA
CTD
PMID:20702594
NCBI chr 1:52,350,597...52,366,205
Ensembl chr 1:52,345,723...52,366,205
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CCDC136
coiled-coil domain containing 136
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCDC136 mRNA
CTD
PMID:32119087
NCBI chr 7:128,790,761...128,822,130
Ensembl chr 7:128,790,757...128,822,132
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CCDC80
coiled-coil domain containing 80
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCDC80 mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr 3:112,596,797...112,641,143
Ensembl chr 3:112,596,797...112,649,530
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CCDC85B
coiled-coil domain containing 85B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCDC85B mRNA
CTD
PMID:23994337
NCBI chr11:65,890,673...65,891,635
Ensembl chr11:65,890,673...65,891,635
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CCK
cholecystokinin
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CCK protein alternative form; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran] results in decreased expression of CCK protein alternative form 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCK protein alternative form
CTD
PMID:10919282
NCBI chr 3:42,257,826...42,266,185
Ensembl chr 3:42,257,825...42,266,185
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CCL11
C-C motif chemokine ligand 11
multiple interactions
ISO
[AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of CCL11 mRNA
CTD
PMID:34256052
NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
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CCL19
C-C motif chemokine ligand 19
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL19 mRNA
CTD
PMID:34256052
NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276
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CCL2
C-C motif chemokine ligand 2
increases expression multiple interactions decreases expression increases secretion
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL2 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCL2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCL2 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCL2 protein; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein]; Sunphenon inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CCL2 protein
CTD
PMID:19265715 PMID:19692669 PMID:20959002 PMID:22262711 PMID:23196670 PMID:24378064 PMID:27663891 PMID:28163111 PMID:28351761 PMID:28973532 PMID:30768972 PMID:35618242 PMID:37080397 More...
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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CCL20
C-C motif chemokine ligand 20
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL20 mRNA
CTD
PMID:23196670 PMID:28351761
NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
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CCL22
C-C motif chemokine ligand 22
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL22 mRNA [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of CCL22 mRNA
CTD
PMID:32119087 PMID:34256052
NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189
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CCL24
C-C motif chemokine ligand 24
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL24 mRNA
CTD
PMID:32119087 PMID:34256052
NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356
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CCL3
C-C motif chemokine ligand 3
increases expression multiple interactions increases secretion
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL3 mRNA Sunphenon inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL3 mRNA] 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL3 mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CCL3 protein]
CTD
PMID:24378064 PMID:30768972
NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
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CCL4
C-C motif chemokine ligand 4
multiple interactions increases secretion
EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL4 mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CCL4 protein]
CTD
PMID:30768972
NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
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CCL5
C-C motif chemokine ligand 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL5 mRNA
CTD
PMID:34256052
NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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CCN1
cellular communication network factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCN1 mRNA
CTD
PMID:23196670
NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
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CCN2
cellular communication network factor 2
affects expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CCN2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCN2 mRNA
CTD
PMID:20702594 PMID:23196670 PMID:32119087
NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
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CCNA2
cyclin A2
multiple interactions increases expression
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with TNF protein] results in increased expression of CCNA2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCNA2 mRNA
CTD
PMID:17557910 PMID:23146750 PMID:23196670
NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
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CCNB1
cyclin B1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCNB1 mRNA
CTD
PMID:23196670
NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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CCND1
cyclin D1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCND1 mRNA
CTD
PMID:23196670
NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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CCND2
cyclin D2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCND2 mRNA
CTD
PMID:23196670
NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353
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CCR1
C-C motif chemokine receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCR1 mRNA
CTD
PMID:34256052
NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313
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CCS
copper chaperone for superoxide dismutase
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CCS mRNA
CTD
PMID:20702594
NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019
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CD14
CD14 molecule
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD14 mRNA
CTD
PMID:23196670
NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
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CD200
CD200 molecule
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD200 mRNA
CTD
PMID:23196670
NCBI chr 3:112,332,573...112,362,812
Ensembl chr 3:112,332,235...112,363,181
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CD200R1
CD200 receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD200R1 mRNA
CTD
PMID:23196670
NCBI chr 3:112,921,205...112,975,103
Ensembl chr 3:112,921,205...112,975,103
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CD24
CD24 molecule
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD24 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD24 mRNA
CTD
PMID:20959002 PMID:23196670 PMID:32119087
NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627
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CD36
CD36 molecule (CD36 blood group)
affects expression increases expression decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CD36 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD36 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD36 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD36 mRNA] 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CD36 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of CD36 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CD36 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD36 mRNA]
CTD
PMID:20702594 PMID:20959002 PMID:22824115 PMID:23994337 PMID:28163111 PMID:28973532 PMID:29216392 PMID:30312631 More...
NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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CD38
CD38 molecule
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD38 mRNA
CTD
PMID:32119087
NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
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CD47
CD47 molecule
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD47 mRNA
CTD
PMID:23196670
NCBI chr 3:108,043,091...108,091,031
Ensembl chr 3:108,043,091...108,091,862
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CD55
CD55 molecule (Cromer blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD55 mRNA
CTD
PMID:23196670
NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
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CD74
CD74 molecule
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD74 mRNA
CTD
PMID:20959002
NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969
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CD93
CD93 molecule
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD93 mRNA
CTD
PMID:32119087
NCBI chr20:23,079,360...23,086,324
Ensembl chr20:23,079,360...23,086,324
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CDC14B
cell division cycle 14B
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDC14B mRNA
CTD
PMID:19692669
NCBI chr 9:96,490,939...96,619,843
Ensembl chr 9:96,490,241...96,619,843
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CDC20
cell division cycle 20
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDC20 mRNA
CTD
PMID:23196670
NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203
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CDCA5
cell division cycle associated 5
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CDCA5 mRNA
CTD
PMID:23994337
NCBI chr11:65,061,093...65,084,040
Ensembl chr11:65,066,300...65,084,164
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CDCA8
cell division cycle associated 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDCA8 mRNA
CTD
PMID:23196670
NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719
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CDH1
cadherin 1
multiple interactions decreases expression
EXP
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]
CTD
PMID:28284859
NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
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CDH17
cadherin 17
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH17 mRNA
CTD
PMID:32119087
NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303
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CDH2
cadherin 2
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]
CTD
PMID:28284859
NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946
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CDH23
cadherin related 23
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH23 mRNA
CTD
PMID:32119087
NCBI chr10:71,396,920...71,815,947
Ensembl chr10:71,396,920...71,815,947
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CDK1
cyclin dependent kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDK1 mRNA
CTD
PMID:23196670
NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
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CDK13
cyclin dependent kinase 13
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDK13 mRNA
CTD
PMID:23994337
NCBI chr 7:39,950,256...40,099,580
Ensembl chr 7:39,950,121...40,099,580
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CDK2
cyclin dependent kinase 2
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CDK2 mRNA
CTD
PMID:21703328
NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
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CDKN1A
cyclin dependent kinase inhibitor 1A
decreases expression multiple interactions increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDKN1A protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased expression of CDKN1A protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDKN1A mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDKN1A mRNA
CTD
PMID:20840854 PMID:20959002 PMID:23196670
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
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CDON
cell adhesion associated, oncogene regulated
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDON mRNA
CTD
PMID:23196670
NCBI chr11:125,956,821...126,063,352
Ensembl chr11:125,955,796...126,063,335
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CEACAM4
CEA cell adhesion molecule 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CEACAM10 mRNA
CTD
PMID:20959002
NCBI chr19:41,613,436...41,627,074
Ensembl chr19:41,619,015...41,627,074
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CEBPB
CCAAT enhancer binding protein beta
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CEBPB mRNA
CTD
PMID:19692669
NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
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CEL
carboxyl ester lipase
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CEL mRNA
CTD
PMID:23146750
NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,981...133,071,861
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CELF2
CUGBP Elav-like family member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CELF2 mRNA
CTD
PMID:23196670
NCBI chr10:10,462,550...11,336,675
Ensembl chr10:10,798,397...11,336,675
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CELF3
CUGBP Elav-like family member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CELF3 mRNA
CTD
PMID:32119087
NCBI chr 1:151,700,058...151,716,803
Ensembl chr 1:151,700,058...151,716,803
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CELSR2
cadherin EGF LAG seven-pass G-type receptor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CELSR2 mRNA
CTD
PMID:32119087
NCBI chr 1:109,249,539...109,275,751
Ensembl chr 1:109,249,539...109,275,751
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CENPN
centromere protein N
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CENPN mRNA
CTD
PMID:23196670
NCBI chr16:81,007,214...81,033,107
Ensembl chr16:81,006,552...81,033,114
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CENPX
centromere protein X
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CENPX mRNA
CTD
PMID:23994337
NCBI chr17:82,018,703...82,022,878
Ensembl chr17:82,018,702...82,024,107
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CEP131
centrosomal protein 131
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CEP131 mRNA
CTD
PMID:32119087
NCBI chr17:81,189,596...81,222,965
Ensembl chr17:81,189,593...81,222,999
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CES1
carboxylesterase 1
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CES1D protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CES1 mRNA
CTD
PMID:19692669 PMID:23457121
NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337
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CES3
carboxylesterase 3
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CES3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CES3 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr16:66,961,266...66,975,149
Ensembl chr16:66,961,245...66,975,149
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CETN4P
centrin 4, pseudogene
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CETN4 mRNA
CTD
PMID:23994337
NCBI chr 4:122,730,189...122,732,458
Ensembl chr 4:122,730,548...122,732,193
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CFAP95
cilia and flagella associated protein 95
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of CFAP95 mRNA
CTD
PMID:30744511
NCBI chr 9:69,820,817...69,906,227
Ensembl chr 9:69,820,817...69,906,227
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CFB
complement factor B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CFB mRNA
CTD
PMID:23196670
NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
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CFHR5
complement factor H related 5
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CFHR5 mRNA
CTD
PMID:19692669
NCBI chr 1:196,975,034...197,009,678
Ensembl chr 1:196,975,010...197,009,678
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CHAD
chondroadherin
affects expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CHAD mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHAD mRNA
CTD
PMID:20702594 PMID:32119087
NCBI chr17:50,464,496...50,468,880
Ensembl chr17:50,464,496...50,468,906
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CHEK1
checkpoint kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHEK1 mRNA
CTD
PMID:23196670
NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255
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CHKA
choline kinase alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHKA mRNA
CTD
PMID:20959002
NCBI chr11:68,052,859...68,121,388
Ensembl chr11:68,052,859...68,121,444
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CHN2
chimerin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CHN2 mRNA
CTD
PMID:23196670
NCBI chr 7:29,146,591...29,514,328
Ensembl chr 7:29,146,547...29,514,328
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CHPT1
choline phosphotransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CHPT1 mRNA
CTD
PMID:23196670
NCBI chr12:101,697,640...101,729,074
Ensembl chr12:101,696,947...101,744,140
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CHST1
carbohydrate sulfotransferase 1
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHST1 mRNA]
CTD
PMID:34256052
NCBI chr11:45,647,689...45,665,622
Ensembl chr11:45,647,689...45,665,622
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CHST15
carbohydrate sulfotransferase 15
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHST15 mRNA
CTD
PMID:23196670
NCBI chr10:124,007,668...124,093,598
Ensembl chr10:124,007,668...124,093,598
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CHST3
carbohydrate sulfotransferase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CHST3 mRNA
CTD
PMID:32119087
NCBI chr10:71,964,395...72,013,558
Ensembl chr10:71,964,395...72,013,558
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CIB2
calcium and integrin binding family member 2
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CIB2 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of CIB2 mRNA
CTD
PMID:23196670 PMID:30744511
NCBI chr15:78,104,606...78,131,535
Ensembl chr15:78,104,606...78,131,535
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CIDEA
cell death inducing DFFA like effector a
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CIDEA mRNA
CTD
PMID:20959002
NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595
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CITED2
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CITED2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CITED2 mRNA
CTD
PMID:16984957 PMID:19692669 PMID:20959002
NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
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CKM
creatine kinase, M-type
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CKM mRNA
CTD
PMID:32119087
NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875
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CKMT1B
creatine kinase, mitochondrial 1B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CKMT1 mRNA
CTD
PMID:23196670
NCBI chr15:43,592,857...43,599,406
Ensembl chr15:43,593,054...43,604,901 Ensembl chr15:43,593,054...43,604,901
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CLCNKA
chloride voltage-gated channel Ka
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CLCNKA mRNA
CTD
PMID:20702594
NCBI chr 1:16,022,036...16,034,050
Ensembl chr 1:16,018,875...16,034,050
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CLDN1
claudin 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of CLDN1 mRNA
CTD
PMID:30744511
NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
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CLDND1
claudin domain containing 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CLDND1 mRNA
CTD
PMID:23196670
NCBI chr 3:98,515,483...98,522,902
Ensembl chr 3:98,497,912...98,523,066
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CLIC2
chloride intracellular channel 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CLIC2 mRNA
CTD
PMID:32119087
NCBI chr X:155,276,211...155,334,614
Ensembl chr X:155,276,211...155,334,657
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CLIC3
chloride intracellular channel 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CLIC3 mRNA
CTD
PMID:23196670
NCBI chr 9:136,994,608...136,996,568
Ensembl chr 9:136,994,608...136,996,568
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CLIC5
chloride intracellular channel 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CLIC5 mRNA
CTD
PMID:23196670
NCBI chr 6:45,880,827...46,129,819
Ensembl chr 6:45,880,827...46,080,348
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CLTB
clathrin light chain B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CLTB mRNA
CTD
PMID:23196670
NCBI chr 5:176,392,455...176,416,569
Ensembl chr 5:176,392,501...176,416,539
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CLTC
clathrin heavy chain
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CLTC mRNA
CTD
PMID:37080397
NCBI chr17:59,619,895...59,696,956
Ensembl chr17:59,619,680...59,696,956
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CLU
clusterin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CLU mRNA
CTD
PMID:32119087
NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
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CMBL
carboxymethylenebutenolidase homolog
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CMBL mRNA
CTD
PMID:23196670
NCBI chr 5:10,277,595...10,307,902
Ensembl chr 5:10,275,875...10,307,902
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CNKSR2
connector enhancer of kinase suppressor of Ras 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CNKSR2 mRNA
CTD
PMID:32119087
NCBI chr X:21,374,418...21,654,689
Ensembl chr X:21,372,801...21,654,695
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CNKSR3
CNKSR family member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CNKSR3 mRNA
CTD
PMID:20959002
NCBI chr 6:154,387,515...154,510,685
Ensembl chr 6:154,387,515...154,510,685
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CNPY1
canopy FGF signaling regulator 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CNPY1 mRNA
CTD
PMID:32119087
NCBI chr 7:155,501,129...155,546,559
Ensembl chr 7:155,474,206...155,555,450
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CNRIP1
cannabinoid receptor interacting protein 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CNRIP1 mRNA
CTD
PMID:23146750
NCBI chr 2:68,284,171...68,319,949
Ensembl chr 2:68,284,171...68,320,051
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CNTFR
ciliary neurotrophic factor receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CNTFR mRNA
CTD
PMID:23196670
NCBI chr 9:34,551,433...34,590,852
Ensembl chr 9:34,551,432...34,590,140
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COL1A1
collagen type I alpha 1 chain
increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of COL1A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of COL1A1 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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COL3A1
collagen type III alpha 1 chain
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of COL3A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of COL3A1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
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COL4A5
collagen type IV alpha 5 chain
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of COL4A5 mRNA
CTD
PMID:19692669
NCBI chr X:108,439,838...108,697,545
Ensembl chr X:108,439,838...108,697,545
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COMT
catechol-O-methyltransferase
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of COMT mRNA
CTD
PMID:30744511
NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
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COQ8A
coenzyme Q8A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of COQ8A mRNA
CTD
PMID:23196670
NCBI chr 1:226,940,294...226,987,544
Ensembl chr 1:226,940,286...226,987,544
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CP
ceruloplasmin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CP mRNA
CTD
PMID:23196670
NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
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CPA1
carboxypeptidase A1
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CPA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPA1 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 7:130,380,494...130,388,108
Ensembl chr 7:130,380,339...130,388,114
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CPA2
carboxypeptidase A2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPA2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 7:130,266,863...130,289,798
Ensembl chr 7:130,266,863...130,289,798
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CPEB4
cytoplasmic polyadenylation element binding protein 4
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CPEB4 mRNA
CTD
PMID:20702594
NCBI chr 5:173,888,349...173,961,980
Ensembl chr 5:173,888,349...173,961,980
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CPED1
cadherin like and PC-esterase domain containing 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPED1 mRNA
CTD
PMID:19692669
NCBI chr 7:120,988,711...121,297,442
Ensembl chr 7:120,988,697...121,297,442
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CPN2
carboxypeptidase N subunit 2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of CPN2 mRNA
CTD
PMID:30744511
NCBI chr 3:194,339,768...194,351,328
Ensembl chr 3:194,339,768...194,351,328
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CPOX
coproporphyrinogen oxidase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CPOX mRNA
CTD
PMID:23994337
NCBI chr 3:98,570,488...98,593,611
Ensembl chr 3:98,579,446...98,593,648
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CPPED1
calcineurin like phosphoesterase domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPPED1 mRNA
CTD
PMID:23196670
NCBI chr16:12,659,799...12,803,887
Ensembl chr16:12,659,799...12,803,887
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CPQ
carboxypeptidase Q
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PGCP mRNA
CTD
PMID:23196670
NCBI chr 8:96,645,242...97,143,501
Ensembl chr 8:96,645,242...97,149,654
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CPT1A
carnitine palmitoyltransferase 1A
decreases expression multiple interactions increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPT1A mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of CPT1A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of CPT1A mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CPT1A mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CPT1A mRNA
CTD
PMID:23196670 PMID:28163111 PMID:28973532 PMID:30312631 PMID:37080397
NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
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CPT2
carnitine palmitoyltransferase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPT2 mRNA
CTD
PMID:23196670
NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
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CPZ
carboxypeptidase Z
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPZ mRNA
CTD
PMID:23196670
NCBI chr 4:8,592,765...8,619,752
Ensembl chr 4:8,592,660...8,619,759
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CREB1
cAMP responsive element binding protein 1
decreases phosphorylation multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of CREB1 protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of and results in decreased activity of CREB1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CREB1 mRNA
CTD
PMID:27509375 PMID:29474705 PMID:37080397
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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CREB3L1
cAMP responsive element binding protein 3 like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CREB3L1 mRNA
CTD
PMID:23196670
NCBI chr11:46,277,662...46,321,409
Ensembl chr11:46,277,662...46,321,409
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CREB3L2
cAMP responsive element binding protein 3 like 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREB3L2 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 7:137,874,979...138,002,086
Ensembl chr 7:137,874,979...138,002,086
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CREM
cAMP responsive element modulator
increases expression decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CREM protein alternative form 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREM mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREM mRNA alternative form AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREM mRNA]
CTD
PMID:16081525 PMID:29474705 PMID:34848246
NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
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CRIP2
cysteine rich protein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CRIP2 mRNA
CTD
PMID:20959002
NCBI chr14:105,472,945...105,480,170
Ensembl chr14:105,472,962...105,480,162
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CRLF1
cytokine receptor like factor 1
decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CRLF1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CRLF1 mRNA
CTD
PMID:23146750 PMID:32119087
NCBI chr19:18,593,237...18,606,799
Ensembl chr19:18,572,220...18,607,741
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CROCC
ciliary rootlet coiled-coil, rootletin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CROCC mRNA
CTD
PMID:32119087
NCBI chr 1:16,914,085...16,972,964
Ensembl chr 1:16,740,273...16,972,964
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CROT
carnitine O-octanoyltransferase
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CROT mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CROT mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 7:87,345,664...87,399,794
Ensembl chr 7:87,345,664...87,399,794
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CRP
C-reactive protein
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CRP mRNA
CTD
PMID:26519613
NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
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CRYL1
crystallin lambda 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CRYL1 mRNA
CTD
PMID:23196670
NCBI chr13:20,403,669...20,525,857
Ensembl chr13:20,403,666...20,525,873
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CRYZL1
crystallin zeta like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CRYZL1 mRNA
CTD
PMID:23196670
NCBI chr21:33,589,341...33,641,741
Ensembl chr21:33,589,341...33,643,926
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CSF1
colony stimulating factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CSF1 mRNA
CTD
PMID:34256052
NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992
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CSF3
colony stimulating factor 3
increases expression increases secretion
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CSF3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CSF3 protein
CTD
PMID:28351761 PMID:29216392 PMID:35618242
NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
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CSMD2
CUB and Sushi multiple domains 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CSMD2 mRNA
CTD
PMID:32119087
NCBI chr 1:33,513,998...34,165,842
Ensembl chr 1:33,513,998...34,165,842
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CSNK2A1
casein kinase 2 alpha 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CSNK2A1 mRNA
CTD
PMID:21703328
NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835
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CSRP2
cysteine and glycine rich protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CSRP2 mRNA
CTD
PMID:20959002
NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
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CTNND1
catenin delta 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CTNND1 mRNA
CTD
PMID:23146750
NCBI chr11:57,761,802...57,819,540
Ensembl chr11:57,753,243...57,819,546
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CTSL
cathepsin L
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CTSL mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469
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CUBN
cubilin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CUBN mRNA
CTD
PMID:32119087
NCBI chr10:16,823,966...17,129,811
Ensembl chr10:16,823,966...17,129,811
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CUX2
cut like homeobox 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CUX2 mRNA
CTD
PMID:19692669
NCBI chr12:111,034,165...111,350,554
Ensembl chr12:111,034,165...111,350,554
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CX3CL1
C-X3-C motif chemokine ligand 1
increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CX3CL1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CX3CL1 mRNA
CTD
PMID:19692669 PMID:23196670 PMID:28351761
NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
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CX3CR1
C-X3-C motif chemokine receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CX3CR1 mRNA
CTD
PMID:34256052
NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735
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CXCL1
C-X-C motif chemokine ligand 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL1 mRNA
CTD
PMID:28351761 PMID:35618242
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
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CXCL10
C-X-C motif chemokine ligand 10
decreases expression increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL10 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL10 mRNA
CTD
PMID:23146750 PMID:28351761 PMID:35618242
NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
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CXCL11
C-X-C motif chemokine ligand 11
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL11 mRNA
CTD
PMID:28351761
NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415
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CXCL12
C-X-C motif chemokine ligand 12
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL12 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL12 mRNA
CTD
PMID:23994337 PMID:34256052
NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
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CXCL13
C-X-C motif chemokine ligand 13
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CXCL13 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL13 mRNA
CTD
PMID:16984957 PMID:23196670
NCBI chr 4:77,511,753...77,611,834
Ensembl chr 4:77,511,753...77,611,834
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CXCL14
C-X-C motif chemokine ligand 14
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL14 mRNA
CTD
PMID:20959002
NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279
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CXCL2
C-X-C motif chemokine ligand 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL2 mRNA
CTD
PMID:28351761
NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
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CXCL5
C-X-C motif chemokine ligand 5
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL5 mRNA
CTD
PMID:23146750
NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677
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CXCL6
C-X-C motif chemokine ligand 6
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL5 mRNA
CTD
PMID:19692669
NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
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CXCL8
C-X-C motif chemokine ligand 8
increases expression increases secretion multiple interactions decreases expression decreases secretion
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL8 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein]; 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of CXCL8 protein]; 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL8 mRNA]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of CXCL8 protein]; lipoxin A4 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL8 mRNA
CTD
PMID:22262711 PMID:25433332 PMID:27663891 PMID:28351761 PMID:30768972 PMID:35618242 More...
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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CXCR5
C-X-C motif chemokine receptor 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCR5 mRNA
CTD
PMID:34256052
NCBI chr11:118,883,892...118,897,787
Ensembl chr11:118,883,892...118,897,787
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CYB5R1
cytochrome b5 reductase 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYB5R1 mRNA
CTD
PMID:37080397
NCBI chr 1:202,961,873...202,967,257
Ensembl chr 1:202,961,873...202,967,275
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CYBB
cytochrome b-245 beta chain
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [NCF1 protein binds to CYBB protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [NCF1 protein modified form binds to CYBB protein]
CTD
PMID:20299304
NCBI chr X:37,780,059...37,813,461
Ensembl chr X:37,780,018...37,813,461
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CYBRD1
cytochrome b reductase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYBRD1 mRNA
CTD
PMID:23196670
NCBI chr 2:171,522,233...171,558,129
Ensembl chr 2:171,522,247...171,558,129
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CYFIP2
cytoplasmic FMR1 interacting protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYFIP2 mRNA
CTD
PMID:20959002
NCBI chr 5:157,266,123...157,395,594
Ensembl chr 5:157,266,079...157,395,595
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CYGB
cytoglobin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYGB mRNA
CTD
PMID:32119087
NCBI chr17:76,527,356...76,551,193
Ensembl chr17:76,527,356...76,551,175
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CYP11A1
cytochrome P450 family 11 subfamily A member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP11A1 mRNA
CTD
PMID:12781204
NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
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CYP11B1
cytochrome P450 family 11 subfamily B member 1
increases activity multiple interactions increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP11B1 protein 3',4'-dimethoxyflavone promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP11B1 mRNA]; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP11B1 mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP11B1 mRNA
CTD
PMID:15703266 PMID:16216300 PMID:16396990 PMID:25765474
NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846
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CYP11B2
cytochrome P450 family 11 subfamily B member 2
multiple interactions increases activity increases expression
EXP
3',4'-dimethoxyflavone promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP11B2 mRNA]; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP11B2 mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP11B2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP11B2 protein
CTD
PMID:14962509 PMID:15703266 PMID:16216300 PMID:16396990 PMID:20574914 PMID:25765474 More...
NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843
G
CYP17A1
cytochrome P450 family 17 subfamily A member 1
decreases activity increases expression decreases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of CYP17A1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP17A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP17A1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP17A1 mRNA]
CTD
PMID:12781204 PMID:15703266 PMID:16216300 PMID:20959002 PMID:34256052
NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
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CYP19A1
cytochrome P450 family 19 subfamily A member 1
increases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP19A1 mRNA [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP19A1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP19A1 mRNA]
CTD
PMID:16216300 PMID:20574914 PMID:22262711 PMID:25765474 PMID:34256052
NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
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CYP1A1
cytochrome P450 family 1 subfamily A member 1
multiple interactions increases activity increases expression affects expression increases expression
EXP ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of and results in increased activity of CYP1A1 protein; 6,2',4'-trimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; 6,2',4'-trimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in increased activity of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [6,2',4'-trimethoxyflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP1A1 mRNA; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [[3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in increased activity of CYP1A1 protein]; Decitabine promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Estradiol promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Oxygen deficiency inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Oxygen deficiency inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; trichostatin A promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA] 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Chlorodiphenyl (54% Chlorine) co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl analog results in increased expression of CYP1A1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased activity of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of CYP1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A1 protein; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Selenic Acid deficiency promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Selenic Acid promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP1A1 mRNA 3,3',4,4',5-pentachlorobiphenyl, PCB-126, increases expression of mRNA in rat liver
CTD RGD
PMID:10986007 PMID:11752103 PMID:12628580 PMID:12781204 PMID:15041469 PMID:15223772 PMID:15352264 PMID:15371557 PMID:15659568 PMID:15908097 PMID:15919853 PMID:15990133 PMID:16049271 PMID:16081525 PMID:16107549 PMID:16339789 PMID:16396990 PMID:16489053 PMID:16628245 PMID:16750337 PMID:16835634 PMID:16983182 PMID:17160104 PMID:17324954 PMID:17342195 PMID:17342196 PMID:17627975 PMID:18042819 PMID:19043309 PMID:19144771 PMID:19447902 PMID:19553035 PMID:19692669 PMID:20570689 PMID:20702594 PMID:20819910 PMID:20959002 PMID:21292640 PMID:21335049 PMID:21513769 PMID:21561885 PMID:21781905 PMID:21865291 PMID:22266287 PMID:23146750 PMID:23196670 PMID:23457121 PMID:23644946 PMID:23674508 PMID:23994337 PMID:24355420 PMID:24378064 PMID:24472611 PMID:25068733 PMID:25116688 PMID:25304490 PMID:25433332 PMID:25530946 PMID:25654323 PMID:25668756 PMID:25765474 PMID:26006071 PMID:26396156 PMID:26410179 PMID:26967026 PMID:27055685 PMID:28284859 PMID:28351761 PMID:29738842 PMID:29947894 PMID:30744511 PMID:30768972 PMID:30991879 PMID:31563530 PMID:32119087 PMID:33026256 PMID:34256052 PMID:34848246 PMID:35618242 PMID:37080397 PMID:23644946 More...
RGD:401794573
NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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CYP1A2
cytochrome P450 family 1 subfamily A member 2
decreases activity multiple interactions increases activity increases expression decreases response to substance affects expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of CYP1A2 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]; [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP1A2 mRNA; [AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]; [aroclor 1260 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A2 mRNA; [MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA; [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP1A2 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]; [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased activity of CYP1A2 protein; [Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl analog results in increased expression of CYP1A2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 protein CYP1A2 results in decreased susceptibility to 3,4,5,3',4'-pentachlorobiphenyl 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP1A2 mRNA
CTD
PMID:10986007 PMID:12635099 PMID:15659567 PMID:16049271 PMID:16628245 PMID:16835634 PMID:17160104 PMID:17342195 PMID:17342196 PMID:19692669 PMID:20702594 PMID:20959002 PMID:20961953 PMID:21335049 PMID:21571617 PMID:23674508 PMID:25068733 PMID:25530946 PMID:26770886 PMID:28163111 PMID:28973532 PMID:30312631 PMID:31563530 PMID:34256052 PMID:36372259 More...
NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
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CYP1B1
cytochrome P450 family 1 subfamily B member 1
multiple interactions affects expression decreases expression increases expression
ISO EXP
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; TNF protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein] 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in increased expression of CYP1B1 mRNA; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; Estradiol promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; Fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP1B1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP1B1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]
CTD
PMID:15041469 PMID:15908097 PMID:15990133 PMID:17557910 PMID:19358281 PMID:19692669 PMID:20959002 PMID:21513769 PMID:21703328 PMID:22262711 PMID:23146750 PMID:23196670 PMID:24378064 PMID:25530946 PMID:25654323 PMID:29738842 PMID:31563530 PMID:31820026 PMID:32119087 PMID:34256052 PMID:35618242 PMID:37080397 More...
NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
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CYP21A2
cytochrome P450 family 21 subfamily A member 2
increases activity increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP21A2 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP21A2 mRNA
CTD
PMID:15703266 PMID:16216300
NCBI chr 6:32,038,415...32,041,644
Ensembl chr 6:32,038,327...32,041,644
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CYP24A1
cytochrome P450 family 24 subfamily A member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP24A1 mRNA
CTD
PMID:31820026
NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
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CYP27B1
cytochrome P450 family 27 subfamily B member 1
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP27B1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP27B1 mRNA]
CTD
PMID:31820026 PMID:34256052
NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986
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CYP2A13
cytochrome P450 family 2 subfamily A member 13
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2A1 mRNA
CTD
PMID:19692669
NCBI chr19:41,088,451...41,096,195
Ensembl chr19:41,088,451...41,096,195
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CYP2B6
cytochrome P450 family 2 subfamily B member 6
increases expression decreases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2B3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B10 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [aroclor 1260 results in increased expression of CYP2B10 mRNA]; aroclor 1260 promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B10 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B3 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B3 mRNA]
CTD
PMID:19692669 PMID:30312631 PMID:34256052
NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
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CYP2C18
cytochrome P450 family 2 subfamily C member 18
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2C11 mRNA
CTD
PMID:31820026
NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
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CYP2C19
cytochrome P450 family 2 subfamily C member 19
increases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C19 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C6 mRNA]
CTD
PMID:19692669 PMID:34256052
NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
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CYP2D7
cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2D1 mRNA
CTD
PMID:32119087
NCBI chr22:42,139,576...42,144,483
Ensembl chr22:42,140,203...42,149,455
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CYP2E1
cytochrome P450 family 2 subfamily E member 1
decreases expression increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2E1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2E1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2E1 mRNA]
CTD
PMID:19692669 PMID:23196670 PMID:28673560 PMID:34256052
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
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CYP2F1
cytochrome P450 family 2 subfamily F member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2F2 mRNA
CTD
PMID:20959002
NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381
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CYP2J2
cytochrome P450 family 2 subfamily J member 2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CYP2J9 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2J9 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
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CYP2S1
cytochrome P450 family 2 subfamily S member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2S1 mRNA
CTD
PMID:23994337
NCBI chr19:41,193,219...41,207,539
Ensembl chr19:41,193,210...41,207,539
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CYP3A4
cytochrome P450 family 3 subfamily A member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP3A2 mRNA
CTD
PMID:31820026
NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
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CYP3A5
cytochrome P450 family 3 subfamily A member 5
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CYP3A13 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP3A13 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
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CYP3A7
cytochrome P450 family 3 subfamily A member 7
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP3A7 mRNA
CTD
PMID:21703328
NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
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CYP4B1
cytochrome P450 family 4 subfamily B member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP4B1 mRNA
CTD
PMID:23196670
NCBI chr 1:46,799,046...46,819,413
Ensembl chr 1:46,757,838...46,819,413
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CYP51A1
cytochrome P450 family 51 subfamily A member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP51 mRNA
CTD
PMID:23196670
NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803
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CYP7A1
cytochrome P450 family 7 subfamily A member 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP7A1 mRNA
CTD
PMID:23146750
NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
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CYTIP
cytohesin 1 interacting protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYTIP mRNA
CTD
PMID:23196670
NCBI chr 2:157,414,619...157,444,089
Ensembl chr 2:157,414,619...157,488,961
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DACT2
dishevelled binding antagonist of beta catenin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DACT2 mRNA
CTD
PMID:20959002
NCBI chr 6:168,292,830...168,319,777
Ensembl chr 6:168,292,830...168,319,777
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DAO
D-amino acid oxidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DAO mRNA
CTD
PMID:20959002
NCBI chr12:108,880,092...108,901,043
Ensembl chr12:108,858,932...108,901,043
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DBP
D-box binding PAR bZIP transcription factor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DBP mRNA
CTD
PMID:32119087
NCBI chr19:48,630,030...48,637,379
Ensembl chr19:48,630,030...48,637,379
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DCAF12L1
DDB1 and CUL4 associated factor 12 like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DCAF12L1 mRNA
CTD
PMID:32119087
NCBI chr X:126,549,383...126,552,814
Ensembl chr X:126,549,383...126,552,814
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DCBLD2
discoidin, CUB and LCCL domain containing 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DCBLD2 mRNA
CTD
PMID:23196670
NCBI chr 3:98,795,941...98,901,695
Ensembl chr 3:98,795,941...98,901,695
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DCLK1
doublecortin like kinase 1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DCLK1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DCLK1 mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr13:35,768,652...36,131,939
Ensembl chr13:35,768,652...36,131,382
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DCN
decorin
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DCN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DCN mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
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DDC
dopa decarboxylase
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DDC mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DDC mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405
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DDIT3
DNA damage inducible transcript 3
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DDIT3 mRNA
CTD
PMID:37080397
NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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DDX39A
DExD-box helicase 39A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DDX39A mRNA
CTD
PMID:23196670
NCBI chr19:14,408,798...14,419,383
Ensembl chr19:14,408,798...14,419,383
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DEFB1
defensin beta 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DEFB1 mRNA
CTD
PMID:20959002
NCBI chr 8:6,870,592...6,877,936
Ensembl chr 8:6,870,592...6,877,936
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DEFB119
defensin beta 119
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DEFB24 mRNA
CTD
PMID:32119087
NCBI chr20:31,377,163...31,390,649
Ensembl chr20:31,377,164...31,390,590
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DEPTOR
DEP domain containing MTOR interacting protein
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DEPTOR mRNA
CTD
PMID:29947894
NCBI chr 8:119,873,722...120,050,918
Ensembl chr 8:119,873,717...120,050,918
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DES
desmin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DES mRNA
CTD
PMID:23196670
NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735
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DGAT2
diacylglycerol O-acyltransferase 2
multiple interactions increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of DGAT2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DGAT2 protein
CTD
PMID:26693162 PMID:28973532
NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
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DGKG
diacylglycerol kinase gamma
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DGKG mRNA
CTD
PMID:35618242
NCBI chr 3:186,147,201...186,362,234
Ensembl chr 3:186,105,668...186,362,234
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DGKZ
diacylglycerol kinase zeta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DGKZ mRNA
CTD
PMID:32119087
NCBI chr11:46,332,926...46,380,554
Ensembl chr11:46,332,905...46,380,554
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DHCR7
7-dehydrocholesterol reductase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DHCR7 mRNA
CTD
PMID:23196670
NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868
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DHH
desert hedgehog signaling molecule
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DHH mRNA
CTD
PMID:32119087
NCBI chr12:49,086,656...49,094,801
Ensembl chr12:49,086,656...49,094,801
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DHRS9
dehydrogenase/reductase 9
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DHRS9 mRNA
CTD
PMID:21703328
NCBI chr 2:169,067,077...169,096,167
Ensembl chr 2:169,064,789...169,096,167
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DIO1
iodothyronine deiodinase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DIO1 mRNA
CTD
PMID:20959002
NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086
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DIPK1A
divergent protein kinase domain 1A
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DIPK1A mRNA
CTD
PMID:19692669
NCBI chr 1:92,832,729...92,961,462
Ensembl chr 1:92,832,737...92,961,522
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DISP1
dispatched RND transporter family member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DISP1 mRNA
CTD
PMID:32119087
NCBI chr 1:222,815,039...223,005,995
Ensembl chr 1:222,815,022...223,005,995
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DKK1
dickkopf WNT signaling pathway inhibitor 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DKK1 mRNA
CTD
PMID:35618242
NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
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DLAT
dihydrolipoamide S-acetyltransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DLAT mRNA
CTD
PMID:20959002
NCBI chr11:112,025,408...112,064,404
Ensembl chr11:112,025,033...112,064,404
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DLG4
discs large MAGUK scaffold protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DLG4 mRNA
CTD
PMID:23196670
NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,836
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DLGAP4
DLG associated protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DLGAP4 mRNA
CTD
PMID:32119087
NCBI chr20:36,306,339...36,528,633
Ensembl chr20:36,306,336...36,528,637
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DLK1
delta like non-canonical Notch ligand 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DLK1 mRNA
CTD
PMID:23196670
NCBI chr14:100,726,892...100,738,224
Ensembl chr14:100,725,705...100,738,224
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DMBT1
deleted in malignant brain tumors 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DMBT1 mRNA
CTD
PMID:23196670
NCBI chr10:122,560,754...122,643,736
Ensembl chr10:122,560,665...122,643,736
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DMD
dystrophin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DMD mRNA
CTD
PMID:23196670
NCBI chr X:31,119,222...33,339,388
Ensembl chr X:31,097,677...33,339,609
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DNAJB11
DnaJ heat shock protein family (Hsp40) member B11
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DNAJB11 mRNA
CTD
PMID:23994337
NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800
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DNM1
dynamin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DNM1 mRNA
CTD
PMID:23196670
NCBI chr 9:128,203,379...128,255,244
Ensembl chr 9:128,191,655...128,255,248
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DNMT1
DNA methyltransferase 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DNMT1 mRNA
CTD
PMID:37080397
NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
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DNMT3A
DNA methyltransferase 3 alpha
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DNMT3A mRNA
CTD
PMID:37080397
NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
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DNMT3B
DNA methyltransferase 3 beta
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DNMT3B mRNA
CTD
PMID:37080397
NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
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DOCK7
dedicator of cytokinesis 7
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DOCK7 mRNA
CTD
PMID:23146750
NCBI chr 1:62,454,726...62,688,386
Ensembl chr 1:62,454,298...62,688,386
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DONSON
DNA replication fork stabilization factor DONSON
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DONSON mRNA
CTD
PMID:23196670
NCBI chr21:33,577,551...33,588,684
Ensembl chr21:33,559,542...33,588,706
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DPEP1
dipeptidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DPEP1 mRNA
CTD
PMID:23196670
NCBI chr16:89,613,308...89,641,540
Ensembl chr16:89,613,308...89,638,456
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DPEP2
dipeptidase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DPEP2 mRNA
CTD
PMID:23196670
NCBI chr16:67,987,390...68,000,619
Ensembl chr16:67,987,394...68,000,586
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DPM2
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DPM2 mRNA
CTD
PMID:19692669
NCBI chr 9:127,935,099...127,937,854
Ensembl chr 9:127,935,099...127,937,854
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DPP4
dipeptidyl peptidase 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DPP4 mRNA
CTD
PMID:37080397
NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394
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DPYSL3
dihydropyrimidinase like 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DPYSL3 mRNA
CTD
PMID:23196670
NCBI chr 5:147,390,808...147,510,068
Ensembl chr 5:147,390,808...147,510,068
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DTNB
dystrobrevin beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DTNB mRNA
CTD
PMID:23196670
NCBI chr 2:25,377,243...25,673,577
Ensembl chr 2:25,377,198...25,673,647
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DUSP1
dual specificity phosphatase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DUSP1 mRNA
CTD
PMID:23196670
NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
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DUSP18
dual specificity phosphatase 18
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DUSP18 mRNA
CTD
PMID:23196670
NCBI chr22:30,652,051...30,667,875
Ensembl chr22:30,652,051...30,667,887
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DUSP6
dual specificity phosphatase 6
multiple interactions increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of DUSP6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DUSP6 mRNA
CTD
PMID:16984957 PMID:23196670
NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501
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DUSP9
dual specificity phosphatase 9
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DUSP9 mRNA
CTD
PMID:23146750
NCBI chr X:153,642,441...153,651,326
Ensembl chr X:153,642,492...153,651,326
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DYSF
dysferlin
affects expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DYSF mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DYSF mRNA
CTD
PMID:20702594 PMID:23994337
NCBI chr 2:71,453,561...71,686,763
Ensembl chr 2:71,453,561...71,686,763
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E2F4
E2F transcription factor 4
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of E2F4 mRNA
CTD
PMID:21703328
NCBI chr16:67,192,155...67,198,918
Ensembl chr16:67,192,155...67,198,918
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EAF2
ELL associated factor 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EAF2 mRNA
CTD
PMID:23196670
NCBI chr 3:121,835,209...121,886,526
Ensembl chr 3:121,835,183...121,886,526
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EARS2
glutamyl-tRNA synthetase 2, mitochondrial
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EARS2 mRNA
CTD
PMID:32119087
NCBI chr16:23,520,754...23,557,375
Ensembl chr16:23,520,754...23,557,731
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ECH1
enoyl-CoA hydratase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ECH1 mRNA
CTD
PMID:23196670
NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841
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ECM1
extracellular matrix protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ECM1 mRNA
CTD
PMID:23196670
NCBI chr 1:150,508,109...150,513,789
Ensembl chr 1:150,508,062...150,513,789
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EDN1
endothelin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EDN1 mRNA
CTD
PMID:23196670
NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
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EEF2
eukaryotic translation elongation factor 2
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of EEF2 mRNA
CTD
PMID:37080397
NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
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EEF2K
eukaryotic elongation factor 2 kinase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EEF2K mRNA
CTD
PMID:32119087
NCBI chr16:22,206,278...22,288,738
Ensembl chr16:22,206,278...22,288,738
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EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EEPD1 mRNA
CTD
PMID:23196670
NCBI chr 7:36,153,254...36,301,538
Ensembl chr 7:36,153,254...36,301,538
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EFCAB11
EF-hand calcium binding domain 11
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EFCAB11 mRNA
CTD
PMID:23196670
NCBI chr14:89,794,669...89,954,777
Ensembl chr14:89,794,669...89,954,777
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EFCC1
EF-hand and coiled-coil domain containing 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EFCC1 mRNA
CTD
PMID:23146750
NCBI chr 3:129,001,304...129,040,742
Ensembl chr 3:129,001,304...129,040,742
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EFNB1
ephrin B1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EFNB1 mRNA
CTD
PMID:23196670
NCBI chr X:68,829,021...68,842,160
Ensembl chr X:68,829,021...68,842,160
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EGF
epidermal growth factor
decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EGF mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein binds to EGFR protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]
CTD
PMID:20959002 PMID:29329451
NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
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EGFLAM
EGF like, fibronectin type III and laminin G domains
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EGFLAM mRNA
CTD
PMID:32119087
NCBI chr 5:38,258,559...38,465,480
Ensembl chr 5:38,258,409...38,465,480
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EGFR
epidermal growth factor receptor
multiple interactions affects binding
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein binds to EGFR protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] 3,4,5,3',4'-pentachlorobiphenyl binds to EGFR protein
CTD
PMID:29329451
NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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EGR1
early growth response 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EGR1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
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EHBP1
EH domain binding protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EHBP1 mRNA
CTD
PMID:20959002
NCBI chr 2:62,673,878...63,046,487
Ensembl chr 2:62,673,851...63,046,487
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EHD3
EH domain containing 3
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of EHD3 mRNA
CTD
PMID:20702594
NCBI chr 2:31,234,152...31,269,451
Ensembl chr 2:31,234,152...31,269,451
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EIF1AX
eukaryotic translation initiation factor 1A X-linked
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of EIF1AX mRNA
CTD
PMID:21703328
NCBI chr X:20,124,525...20,141,838
Ensembl chr X:20,124,525...20,141,838
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EIF3F
eukaryotic translation initiation factor 3 subunit F
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of EIF3F mRNA
CTD
PMID:37080397
NCBI chr11:7,987,337...8,001,852
Ensembl chr11:7,970,251...8,001,862
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ELN
elastin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ELN mRNA
CTD
PMID:32119087
NCBI chr 7:74,028,173...74,069,907
Ensembl chr 7:74,027,789...74,069,907
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ELOVL5
ELOVL fatty acid elongase 5
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ELOVL5 mRNA
CTD
PMID:20702594
NCBI chr 6:53,267,404...53,348,950
Ensembl chr 6:53,267,398...53,349,179
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ELOVL6
ELOVL fatty acid elongase 6
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ELOVL6 mRNA
CTD
PMID:23196670
NCBI chr 4:110,045,846...110,199,202
Ensembl chr 4:110,045,846...110,199,199
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EMP1
epithelial membrane protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EMP1 mRNA
CTD
PMID:23196670
NCBI chr12:13,196,726...13,219,941
Ensembl chr12:13,196,723...13,219,941
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EMP2
epithelial membrane protein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EMP2 mRNA
CTD
PMID:23196670
NCBI chr16:10,528,422...10,580,598
Ensembl chr16:10,528,422...10,580,632
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ENAH
ENAH actin regulator
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ENAH mRNA
CTD
PMID:23196670
NCBI chr 1:225,486,829...225,653,878
Ensembl chr 1:225,486,765...225,653,142
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ENC1
ectodermal-neural cortex 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ENC1 mRNA
CTD
PMID:32119087
NCBI chr 5:74,627,409...74,640,728
Ensembl chr 5:74,627,406...74,641,424
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ENO3
enolase 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ENO3 mRNA
CTD
PMID:23196670
NCBI chr17:4,948,710...4,957,129
Ensembl chr17:4,948,092...4,957,131
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ENPEP
glutamyl aminopeptidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENPEP mRNA
CTD
PMID:20959002
NCBI chr 4:110,476,155...110,565,285
Ensembl chr 4:110,365,733...110,565,285
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ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENPP1 mRNA
CTD
PMID:23196670
NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155
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ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ENPP2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENPP2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453
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ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENPP3 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr 6:131,637,302...131,747,410
Ensembl chr 6:131,628,442...131,747,418
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ENTPD3
ectonucleoside triphosphate diphosphohydrolase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENTPD3 mRNA
CTD
PMID:23196670
NCBI chr 3:40,387,184...40,428,744
Ensembl chr 3:40,387,184...40,428,744
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EPAS1
endothelial PAS domain protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPAS1 mRNA
CTD
PMID:23196670
NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
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EPB41L1
erythrocyte membrane protein band 4.1 like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPB41L1 mRNA
CTD
PMID:23196670
NCBI chr20:36,091,414...36,232,799
Ensembl chr20:36,091,504...36,232,799
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EPCAM
epithelial cell adhesion molecule
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EPCAM mRNA
CTD
PMID:20959002
NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601
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EPHA7
EPH receptor A7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPHA7 mRNA
CTD
PMID:23196670
NCBI chr 6:93,240,020...93,419,559
Ensembl chr 6:93,240,020...93,419,687
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EPHB1
EPH receptor B1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EPHB1 mRNA
CTD
PMID:32119087
NCBI chr 3:134,795,260...135,260,467
Ensembl chr 3:134,795,260...135,260,467
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EPHX1
epoxide hydrolase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EPHX1 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
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EPHX2
epoxide hydrolase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPHX2 mRNA
CTD
PMID:23196670
NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
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EPS8
EGFR pathway substrate 8, signaling adaptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPS8 mRNA
CTD
PMID:32119087
NCBI chr12:15,620,134...15,789,388
Ensembl chr12:15,620,134...15,882,329
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EREG
epiregulin
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EREG mRNA
CTD
PMID:35618242
NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749
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ERO1A
endoplasmic reticulum oxidoreductase 1 alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ERO1A mRNA
CTD
PMID:23196670
NCBI chr14:52,639,915...52,695,558
Ensembl chr14:52,639,915...52,695,900
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ESM1
endothelial cell specific molecule 1
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ESM1 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of ESM1 mRNA
CTD
PMID:20959002 PMID:30744511
NCBI chr 5:54,977,867...54,985,593
Ensembl chr 5:54,977,867...55,022,671
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ESR1
estrogen receptor 1
affects binding multiple interactions affects expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl binds to ESR1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to KDM4B intron]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to RELA promoter]; ESR1 protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KDM4B mRNA]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ESR1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ESR1 mRNA
CTD
PMID:16489053 PMID:21703328 PMID:26519613 PMID:37080397
NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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ESRRA
estrogen related receptor alpha
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ESRRA mRNA
CTD
PMID:37080397
NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743
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ESRRG
estrogen related receptor gamma
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ESRRG mRNA
CTD
PMID:23196670
NCBI chr 1:216,503,246...217,137,702
Ensembl chr 1:216,503,246...217,137,755
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ETFBKMT
electron transfer flavoprotein subunit beta lysine methyltransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ETFBKMT mRNA
CTD
PMID:23196670
NCBI chr12:31,647,160...31,673,114
Ensembl chr12:31,647,160...31,673,114
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ETS1
ETS proto-oncogene 1, transcription factor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ETS1 mRNA
CTD
PMID:23196670
NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558
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EXOC3
exocyst complex component 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EXOC3 mRNA
CTD
PMID:20959002
NCBI chr 5:443,176...467,290
Ensembl chr 5:443,175...471,937
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EXOC3L4
exocyst complex component 3 like 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EXOC3L4 mRNA
CTD
PMID:32119087
NCBI chr14:103,094,174...103,110,559
Ensembl chr14:103,094,725...103,110,559
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EXPH5
exophilin 5
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EXPH5 mRNA
CTD
PMID:19692669
NCBI chr11:108,505,435...108,607,536
Ensembl chr11:108,505,435...108,593,768
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EXTL3
exostosin like glycosyltransferase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EXTL3 mRNA
CTD
PMID:23196670
NCBI chr 8:28,607,736...28,755,599
Ensembl chr 8:28,600,469...28,756,561
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F11R
F11 receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of F11R mRNA
CTD
PMID:23196670
NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175
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F2R
coagulation factor II thrombin receptor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of F2R mRNA
CTD
PMID:23196670
NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770
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F2RL1
F2R like trypsin receptor 1
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of F2RL1 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315
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F3
coagulation factor III, tissue factor
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of F3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of F3 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
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FABP1
fatty acid binding protein 1
multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of FABP1 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FABP1 mRNA]
CTD
PMID:30312631
NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
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FABP4
fatty acid binding protein 4
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FABP4 mRNA
CTD
PMID:22262711 PMID:25304490
NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
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FABP5
fatty acid binding protein 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FABP5 mRNA
CTD
PMID:20959002
NCBI chr 8:81,280,536...81,284,775
Ensembl chr 8:81,280,536...81,284,777
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FADS1
fatty acid desaturase 1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FADS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FADS1 mRNA
CTD
PMID:23196670 PMID:29216392
NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318
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FAH
fumarylacetoacetate hydrolase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FAH mRNA
CTD
PMID:23196670
NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946
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FAM110B
family with sequence similarity 110 member B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FAM110B mRNA
CTD
PMID:23196670
NCBI chr 8:57,994,523...58,148,784
Ensembl chr 8:57,994,523...58,204,279
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FAM110C
family with sequence similarity 110 member C
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FAM110C mRNA
CTD
PMID:23196670
NCBI chr 2:38,814...46,505
Ensembl chr 2:38,814...46,870
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FAM131B
family with sequence similarity 131 member B
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FAM131B mRNA
CTD
PMID:23146750
NCBI chr 7:143,353,400...143,382,304
Ensembl chr 7:143,353,400...143,362,770
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FAM13A
family with sequence similarity 13 member A
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of FAM13A mRNA
CTD
PMID:30744511
NCBI chr 4:88,725,960...89,057,185
Ensembl chr 4:88,725,955...89,111,398
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FAM151A
family with sequence similarity 151 member A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FAM151A mRNA
CTD
PMID:23196670
NCBI chr 1:54,609,181...54,623,525
Ensembl chr 1:54,609,181...54,623,556
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FAM220A
family with sequence similarity 220 member A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FAM220A mRNA
CTD
PMID:32119087
NCBI chr 7:6,329,411...6,348,967
Ensembl chr 7:6,329,411...6,348,981
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FAM83F
family with sequence similarity 83 member F
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FAM83F mRNA
CTD
PMID:32119087
NCBI chr22:39,994,954...40,043,534
Ensembl chr22:39,994,954...40,043,534
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FANCD2
FA complementation group D2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FANCD2 mRNA
CTD
PMID:23196670
NCBI chr 3:10,026,437...10,101,932
Ensembl chr 3:10,026,370...10,101,932
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FAS
Fas cell surface death receptor
multiple interactions increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FAS mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FAS mRNA
CTD
PMID:28973532
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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FASN
fatty acid synthase
decreases expression multiple interactions affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FASN mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of FASN mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of FASN mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FASN mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of FASN mRNA
CTD
PMID:19692669 PMID:20959002 PMID:28163111 PMID:30312631 PMID:37080397
NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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FBLN5
fibulin 5
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FBLN5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBLN5 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr14:91,869,411...91,947,694
Ensembl chr14:91,869,411...91,947,987
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FBN1
fibrillin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBN1 mRNA
CTD
PMID:23196670
NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,313...48,645,721
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FBN2
fibrillin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBN2 mRNA
CTD
PMID:32119087
NCBI chr 5:128,257,909...128,538,245
Ensembl chr 5:128,257,909...128,659,185
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FBP1
fructose-bisphosphatase 1
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FBP1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FBP1 mRNA]
CTD
PMID:34256052
NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249
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FBP2
fructose-bisphosphatase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBP2 mRNA
CTD
PMID:23196670
NCBI chr 9:94,558,720...94,593,824
Ensembl chr 9:94,558,720...94,593,824
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FBXO21
F-box protein 21
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FBXO21 mRNA
CTD
PMID:23994337
NCBI chr12:117,141,991...117,190,470
Ensembl chr12:117,141,991...117,190,470
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FBXO24
F-box protein 24
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBXO24 mRNA
CTD
PMID:23146750
NCBI chr 7:100,586,328...100,601,117
Ensembl chr 7:100,583,982...100,601,117
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FBXO32
F-box protein 32
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBXO32 mRNA
CTD
PMID:23196670
NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
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FBXW9
F-box and WD repeat domain containing 9
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of FBXW9 mRNA
CTD
PMID:20702594
NCBI chr19:12,688,916...12,696,631
Ensembl chr19:12,688,053...12,696,631
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FCAR
Fc alpha receptor
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FCAR mRNA
CTD
PMID:23146750
NCBI chr19:54,874,235...54,891,420
Ensembl chr19:54,874,235...54,891,420
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FCGR2A
Fc gamma receptor IIa
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FCGR3 mRNA
CTD
PMID:23196670
NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013
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FDX1
ferredoxin 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of FDX1 mRNA
CTD
PMID:16984957
NCBI chr11:110,429,331...110,464,884
Ensembl chr11:110,429,948...110,464,884
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FDXR
ferredoxin reductase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FDXR mRNA
CTD
PMID:23196670
NCBI chr17:74,862,497...74,872,994
Ensembl chr17:74,862,497...74,873,031
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FEN1
flap structure-specific endonuclease 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FEN1 mRNA
CTD
PMID:23196670
NCBI chr11:61,792,911...61,797,238
Ensembl chr11:61,792,911...61,797,238
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FGA
fibrinogen alpha chain
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGA mRNA
CTD
PMID:19692669
NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
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FGD5
FYVE, RhoGEF and PH domain containing 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGD5 mRNA
CTD
PMID:23994337
NCBI chr 3:14,810,688...14,934,571
Ensembl chr 3:14,810,853...14,934,571
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FGF1
fibroblast growth factor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF1 mRNA
CTD
PMID:23196670
NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
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FGF13
fibroblast growth factor 13
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF13 mRNA
CTD
PMID:23196670
NCBI chr X:138,614,727...139,205,023
Ensembl chr X:138,614,727...139,222,777
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FGF2
fibroblast growth factor 2
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGF2 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236
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FGF21
fibroblast growth factor 21
decreases expression multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF21 mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of FGF21 mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of FGF21 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF21 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGF21 mRNA
CTD
PMID:28163111 PMID:29474705 PMID:30312631
NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
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FGF9
fibroblast growth factor 9
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGF9 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF9 mRNA
CTD
PMID:19358281 PMID:23196670
NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498
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FGFR2
fibroblast growth factor receptor 2
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGFR2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGFR2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
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FGGY
FGGY carbohydrate kinase domain containing
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGGY mRNA
CTD
PMID:19692669
NCBI chr 1:59,296,378...59,762,730
Ensembl chr 1:59,296,638...59,810,647
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FHL2
four and a half LIM domains 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FHL2 mRNA
CTD
PMID:19692669
NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513
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FHOD1
formin homology 2 domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FHOD1 mRNA
CTD
PMID:32119087
NCBI chr16:67,229,389...67,247,481
Ensembl chr16:67,229,387...67,247,481
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FIGNL1
fidgetin like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FIGNL1 mRNA
CTD
PMID:23196670
NCBI chr 7:50,444,133...50,450,350
Ensembl chr 7:50,444,128...50,450,390
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FILIP1
filamin A interacting protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FILIP1 mRNA
CTD
PMID:23196670
NCBI chr 6:75,291,859...75,493,800
Ensembl chr 6:75,291,859...75,493,800
G
FKBP14
FKBP prolyl isomerase 14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FKBP14 mRNA
CTD
PMID:23196670
NCBI chr 7:30,005,923...30,026,702
Ensembl chr 7:30,010,587...30,026,702
G
FKBP4
FKBP prolyl isomerase 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FKBP4 mRNA
CTD
PMID:20959002
NCBI chr12:2,794,970...2,805,423
Ensembl chr12:2,794,970...2,805,423
G
FKBP9
FKBP prolyl isomerase 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FKBP9 mRNA
CTD
PMID:23196670
NCBI chr 7:32,957,440...33,006,928
Ensembl chr 7:32,957,404...33,006,930
G
FLNB
filamin B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FLNB mRNA
CTD
PMID:19692669
NCBI chr 3:58,008,422...58,172,251
Ensembl chr 3:58,008,398...58,172,251
G
FLOT1
flotillin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FLOT1 mRNA
CTD
PMID:23196670
NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732
G
FLT1
fms related receptor tyrosine kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FLT1 mRNA
CTD
PMID:23196670
NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
G
FLVCR2
FLVCR choline and putative heme transporter 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FLVCR2 mRNA
CTD
PMID:23196670
NCBI chr14:75,578,620...75,648,167
Ensembl chr14:75,578,620...75,663,214
G
FMO1
flavin containing dimethylaniline monoxygenase 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of FMO1 mRNA
CTD
PMID:16984957
NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978
G
FMO3
flavin containing dimethylaniline monoxygenase 3
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FMO3 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FMO3 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of FMO3 mRNA
CTD
PMID:28163111 PMID:28973532
NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819
G
FMOD
fibromodulin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FMOD mRNA
CTD
PMID:23196670
NCBI chr 1:203,340,628...203,351,122
Ensembl chr 1:203,340,628...203,351,758
G
FN1
fibronectin 1
decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FN1 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
G
FOS
Fos proto-oncogene, AP-1 transcription factor subunit
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FOS mRNA
CTD
PMID:35618242
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
G
FOXA2
forkhead box A2
increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FOXA2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of FOXA2 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,580,998...22,585,455
G
FOXA3
forkhead box A3
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of FOXA3 mRNA
CTD
PMID:21703328
NCBI chr19:45,864,326...45,873,797
Ensembl chr19:45,863,989...45,873,797
G
FOXD4
forkhead box D4
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FOXD4 mRNA
CTD
PMID:23146750
NCBI chr 9:116,231...118,417
Ensembl chr 9:116,231...118,417
G
FOXN3
forkhead box N3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FOXN3 mRNA
CTD
PMID:32119087
NCBI chr14:89,156,177...89,619,165
Ensembl chr14:89,124,871...89,619,149
G
FOXO1
forkhead box O1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FOXO1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FOXO1 mRNA
CTD
PMID:27509375 PMID:37080397
NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
G
FOXO3
forkhead box O3
multiple interactions decreases phosphorylation
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of FOXO3 protein]; MDM2 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of FOXO3 protein]
CTD
PMID:20840854
NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
G
FOXQ1
forkhead box Q1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FOXQ1 mRNA
CTD
PMID:23196670
NCBI chr 6:1,312,098...1,314,758
Ensembl chr 6:1,312,098...1,314,758
G
FSCN1
fascin actin-bundling protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FSCN1 mRNA
CTD
PMID:32119087
NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655
G
FSHB
follicle stimulating hormone subunit beta
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FSHB protein
CTD
PMID:34256052
NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
G
FSIP1
fibrous sheath interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FSIP1 mRNA
CTD
PMID:23196670
NCBI chr15:39,597,440...39,782,841
Ensembl chr15:39,588,357...39,782,841
G
FST
follistatin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FST mRNA
CTD
PMID:23196670
NCBI chr 5:53,480,629...53,487,134
Ensembl chr 5:53,480,626...53,487,134
G
FTL
ferritin light chain
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FTL protein
CTD
PMID:25686467
NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879
G
FUCA1
alpha-L-fucosidase 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FUCA1 mRNA
CTD
PMID:23146750
NCBI chr 1:23,845,077...23,868,290
Ensembl chr 1:23,845,077...23,868,290
G
FUT7
fucosyltransferase 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FUT7 mRNA
CTD
PMID:23196670
NCBI chr 9:137,030,174...137,032,088
Ensembl chr 9:137,030,174...137,032,088
G
FXYD1
FXYD domain containing ion transport regulator 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FXYD1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr19:35,137,188...35,143,109
Ensembl chr19:35,138,824...35,143,109
G
FYN
FYN proto-oncogene, Src family tyrosine kinase
multiple interactions decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of FYN protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FYN protein
CTD
PMID:24709675
NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
G
FZD4
frizzled class receptor 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FZD4 mRNA
CTD
PMID:23196670
NCBI chr11:86,945,679...86,955,395
Ensembl chr11:86,945,679...86,955,395
G
FZD9
frizzled class receptor 9
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FZD9 mRNA
CTD
PMID:23146750
NCBI chr 7:73,433,778...73,436,120
Ensembl chr 7:73,433,778...73,436,120
G
G0S2
G0/G1 switch 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G0S2 mRNA
CTD
PMID:20959002
NCBI chr 1:209,675,412...209,676,390
Ensembl chr 1:209,675,412...209,676,390
G
G6PC1
glucose-6-phosphatase catalytic subunit 1
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of G6PC1 mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of G6PC1 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA]
CTD
PMID:27509375 PMID:28163111 PMID:29474705 PMID:30312631 PMID:34848246
NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
G
G6PD
glucose-6-phosphate dehydrogenase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of G6PDX mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr X:154,531,390...154,547,569
Ensembl chr X:154,517,825...154,547,572
G
GADD45A
growth arrest and DNA damage inducible alpha
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GADD45A mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GADD45A mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
G
GADD45G
growth arrest and DNA damage inducible gamma
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GADD45G mRNA
CTD
PMID:23196670
NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
G
GALE
UDP-galactose-4-epimerase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GALE mRNA
CTD
PMID:23196670
NCBI chr 1:23,795,599...23,800,754
Ensembl chr 1:23,795,599...23,800,781
G
GALNT10
polypeptide N-acetylgalactosaminyltransferase 10
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GALNT10 mRNA
CTD
PMID:23196670
NCBI chr 5:154,190,733...154,420,984
Ensembl chr 5:154,190,730...154,420,984
G
GALNT14
polypeptide N-acetylgalactosaminyltransferase 14
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GALNT14 mRNA
CTD
PMID:23196670
NCBI chr 2:30,886,782...31,138,440
Ensembl chr 2:30,910,467...31,155,202
G
GAMT
guanidinoacetate N-methyltransferase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GAMT mRNA
CTD
PMID:23196670
NCBI chr19:1,397,026...1,401,542
Ensembl chr19:1,397,026...1,401,570
G
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of GAPDH mRNA
CTD
PMID:37080397
NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
G
GAR1
GAR1 ribonucleoprotein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GAR1 mRNA
CTD
PMID:23196670
NCBI chr 4:109,815,510...109,824,737
Ensembl chr 4:109,815,510...109,824,740
G
GAS1
growth arrest specific 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GAS1 mRNA
CTD
PMID:23994337
NCBI chr 9:86,944,362...86,947,506
Ensembl chr 9:86,944,362...86,947,506
G
GASK1B
golgi associated kinase 1B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GASK1B mRNA
CTD
PMID:23196670
NCBI chr 4:158,124,474...158,173,025
Ensembl chr 4:158,124,474...158,173,318
G
GATA4
GATA binding protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GATA4 mRNA
CTD
PMID:20959002
NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
G
GATA6
GATA binding protein 6
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GATA6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GATA6 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
G
GATD3
glutamine amidotransferase class 1 domain containing 3
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GATD3 mRNA
CTD
PMID:19692669
NCBI chr21:44,133,683...44,145,711
Ensembl chr21:44,133,610...44,210,114
G
GCGR
glucagon receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GCGR mRNA
CTD
PMID:23994337
NCBI chr17:81,804,150...81,814,008
Ensembl chr17:81,804,132...81,814,008
G
GCK
glucokinase
decreases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GCK mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of GCK mRNA
CTD
PMID:20959002 PMID:37080397
NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
G
GCKR
glucokinase regulator
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GCKR mRNA]
CTD
PMID:34256052
NCBI chr 2:27,496,839...27,523,684
Ensembl chr 2:27,496,839...27,523,684
G
GCLC
glutamate-cysteine ligase catalytic subunit
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GCLC mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
G
GCNT1
glucosaminyl (N-acetyl) transferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GCNT1 mRNA
CTD
PMID:23196670
NCBI chr 9:76,393,869...76,507,416
Ensembl chr 9:76,419,850...76,651,203
G
GCNT2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GCNT2 mRNA
CTD
PMID:23196670
NCBI chr 6:10,521,351...10,629,368
Ensembl chr 6:10,492,223...10,629,368
G
GDA
guanine deaminase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GDA mRNA
CTD
PMID:23196670
NCBI chr 9:72,114,608...72,259,869
Ensembl chr 9:72,114,595...72,257,193
G
GDF15
growth differentiation factor 15
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GDF15 mRNA
CTD
PMID:19692669 PMID:32119087
NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176
G
GFRA1
GDNF family receptor alpha 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GFRA1 mRNA
CTD
PMID:23196670
NCBI chr10:116,056,925...116,274,705
Ensembl chr10:116,056,925...116,276,803
G
GFRA2
GDNF family receptor alpha 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GFRA2 mRNA
CTD
PMID:32119087
NCBI chr 8:21,690,398...21,812,345
Ensembl chr 8:21,690,398...21,812,357
G
GGT1
gamma-glutamyltransferase 1
multiple interactions decreases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GGT1 mRNA]
CTD
PMID:34256052
NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005
G
GGTA1
glycoprotein alpha-galactosyltransferase 1 (inactive)
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GGTA1 mRNA
CTD
PMID:23146750
NCBI chr 9:121,444,990...121,499,844
Ensembl chr 9:121,444,991...121,499,844
G
GH1
growth hormone 1
multiple interactions
ISO
[2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of GH1 mRNA
CTD
PMID:19327374
NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
G
GHR
growth hormone receptor
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GHR mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GHR mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
G
GK
glycerol kinase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GK mRNA
CTD
PMID:29216392
NCBI chr X:30,653,423...30,731,462
Ensembl chr X:30,653,359...30,731,462
G
GLB1L3
galactosidase beta 1 like 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GLB1L3 mRNA
CTD
PMID:23196670
NCBI chr11:134,275,767...134,325,304
Ensembl chr11:134,274,245...134,319,564
G
GLIPR1
GLI pathogenesis related 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GLIPR1 mRNA
CTD
PMID:23196670
NCBI chr12:75,480,755...75,503,863
Ensembl chr12:75,480,753...75,503,863
G
GLRX2
glutaredoxin 2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GLRX2 mRNA
CTD
PMID:24378064
NCBI chr 1:193,096,465...193,106,114
Ensembl chr 1:193,090,866...193,106,114
G
GLS2
glutaminase 2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of GLS2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GLS2 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr12:56,470,952...56,488,161
Ensembl chr12:56,470,944...56,488,414
G
GLUD1
glutamate dehydrogenase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GLUD1 mRNA
CTD
PMID:19692669
NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843
G
GMPR
guanosine monophosphate reductase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GMPR mRNA
CTD
PMID:23196670
NCBI chr 6:16,238,587...16,295,549
Ensembl chr 6:16,238,587...16,295,549
G
GNA14
G protein subunit alpha 14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GNA14 mRNA
CTD
PMID:32119087
NCBI chr 9:77,423,079...77,648,322
Ensembl chr 9:77,423,079...77,648,322
G
GNB1
G protein subunit beta 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GNB1 mRNA
CTD
PMID:20959002
NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,892,292
G
GNG13
G protein subunit gamma 13
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of GNG13 mRNA
CTD
PMID:30744511
NCBI chr16:798,041...800,734
Ensembl chr16:798,041...800,734
G
GNG8
G protein subunit gamma 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GNG8 mRNA
CTD
PMID:23196670
NCBI chr19:46,633,953...46,639,326
Ensembl chr19:46,633,953...46,636,541
G
GNPDA1
glucosamine-6-phosphate deaminase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GNPDA1 mRNA
CTD
PMID:23994337
NCBI chr 5:142,000,671...142,013,027
Ensembl chr 5:141,991,749...142,013,041
G
GOLGA3
golgin A3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GOLGA3 mRNA
CTD
PMID:23994337
NCBI chr12:132,768,914...132,829,081
Ensembl chr12:132,768,902...132,829,143
G
GOT2
glutamic-oxaloacetic transaminase 2
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of GOT2 mRNA
CTD
PMID:21703328
NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
G
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPAM mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377
G
GPC3
glypican 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPC3 mRNA
CTD
PMID:23196670
NCBI chr X:133,535,745...133,985,594
Ensembl chr X:133,535,745...133,987,100
G
GPC6
glypican 6
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPC6 mRNA
CTD
PMID:29947894
NCBI chr13:93,216,529...94,408,020
Ensembl chr13:93,226,807...94,408,020
G
GPD2
glycerol-3-phosphate dehydrogenase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPD2 mRNA
CTD
PMID:23994337
NCBI chr 2:156,400,281...156,586,403
Ensembl chr 2:156,435,290...156,613,735
G
GPM6B
glycoprotein M6B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPM6B mRNA
CTD
PMID:23196670
NCBI chr X:13,770,939...13,938,638
Ensembl chr X:13,770,939...13,938,638
G
GPNMB
glycoprotein nmb
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPNMB mRNA
CTD
PMID:23196670
NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108
G
GPR149
G protein-coupled receptor 149
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPR149 mRNA
CTD
PMID:23196670
NCBI chr 3:154,334,943...154,430,190
Ensembl chr 3:154,334,943...154,430,190
G
GPR15
G protein-coupled receptor 15
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPR15 mRNA
CTD
PMID:32119087
NCBI chr 3:98,531,978...98,534,681
Ensembl chr 3:98,531,978...98,534,681
G
GPR35
G protein-coupled receptor 35
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPR35 mRNA
CTD
PMID:23994337
NCBI chr 2:240,605,430...240,633,159
Ensembl chr 2:240,605,430...240,633,159
G
GPR68
G protein-coupled receptor 68
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPR68 mRNA
CTD
PMID:23146750
NCBI chr14:91,232,532...91,270,790
Ensembl chr14:91,232,532...91,253,925
G
GPR88
G protein-coupled receptor 88
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPR88 mRNA
CTD
PMID:23196670
NCBI chr 1:100,538,139...100,542,021
Ensembl chr 1:100,538,139...100,542,021
G
GPT
glutamic--pyruvic transaminase
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPT mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased activity of GPT protein
CTD
PMID:20959002 PMID:33096110
NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
G
GPX1
glutathione peroxidase 1
decreases expression multiple interactions affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPX1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPX1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of GPX1 mRNA
CTD
PMID:34256052 PMID:37080397
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
G
GPX2
glutathione peroxidase 2
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX2 mRNA]
CTD
PMID:34256052
NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
G
GPX3
glutathione peroxidase 3
increases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX3 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GPX3 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:24378064
NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
G
GPX5
glutathione peroxidase 5
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX5 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX5 mRNA]
CTD
PMID:34256052
NCBI chr 6:28,525,881...28,534,955
Ensembl chr 6:28,525,881...28,534,955
G
GRB14
growth factor receptor bound protein 14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GRB14 mRNA
CTD
PMID:23196670
NCBI chr 2:164,492,417...164,621,482
Ensembl chr 2:164,492,417...164,621,482
G
GREB1
growth regulating estrogen receptor binding 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GREB1 mRNA
CTD
PMID:32119087
NCBI chr 2:11,482,888...11,642,788
Ensembl chr 2:11,482,341...11,642,788
G
GRHPR
glyoxylate and hydroxypyruvate reductase
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of GRHPR protein
CTD
PMID:23457121
NCBI chr 9:37,422,435...37,439,494
Ensembl chr 9:37,422,666...37,436,990
G
GRIK4
glutamate ionotropic receptor kainate type subunit 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GRIK4 mRNA
CTD
PMID:32119087
NCBI chr11:120,511,748...120,988,906
Ensembl chr11:120,511,746...120,988,906
G
GRINA
glutamate ionotropic receptor NMDA type subunit associated protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GRINA mRNA
CTD
PMID:23196670
NCBI chr 8:143,990,056...143,993,415
Ensembl chr 8:143,990,056...143,993,415
G
GRIP1
glutamate receptor interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GRIP1 mRNA
CTD
PMID:23196670
NCBI chr12:66,347,431...67,069,338
Ensembl chr12:66,347,431...67,069,162
G
GRK5
G protein-coupled receptor kinase 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GRK5 mRNA
CTD
PMID:23196670
NCBI chr10:119,207,571...119,459,745
Ensembl chr10:119,207,571...119,459,745
G
GSDMD
gasdermin D
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSDMD mRNA
CTD
PMID:23994337
NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
G
GSK3B
glycogen synthase kinase 3 beta
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of GSK3B mRNA
CTD
PMID:37080397
NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
G
GSR
glutathione-disulfide reductase
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSR mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] results in increased expression of GSR protein
CTD
PMID:24378064
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
G
GSS
glutathione synthetase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSS mRNA
CTD
PMID:23196670
NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
G
GSTA2
glutathione S-transferase alpha 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTA2 mRNA
CTD
PMID:20959002
NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475
G
GSTA5
glutathione S-transferase alpha 5
multiple interactions increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTA1 mRNA
CTD
PMID:24378064 PMID:37080397
NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843
G
GSTM1
glutathione S-transferase mu 1
decreases expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM1 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM5 mRNA
CTD
PMID:18723825 PMID:20959002 PMID:23196670 PMID:24378064
NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
G
GSTM2
glutathione S-transferase mu 2
decreases expression increases expression affects expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of GSTM2 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTM2 mRNA
CTD
PMID:18042819 PMID:20702594 PMID:23196670 PMID:24378064
NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
G
GSTM3
glutathione S-transferase mu 3
decreases expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA] AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA]
CTD
PMID:23196670 PMID:24378064 PMID:34256052
NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038
G
GSTM4
glutathione S-transferase mu 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM4 mRNA
CTD
PMID:37080397
NCBI chr 1:109,656,099...109,667,727
Ensembl chr 1:109,656,099...109,665,496
G
GSTM5
glutathione S-transferase mu 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM5 mRNA
CTD
PMID:23196670
NCBI chr 1:109,711,751...109,718,268
Ensembl chr 1:109,711,780...109,775,428
G
GSTP1
glutathione S-transferase pi 1
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTP1 mRNA]
CTD
PMID:34256052
NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
G
GSTT2B
glutathione S-transferase theta 2B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTT2 mRNA
CTD
PMID:23994337
NCBI chr22:23,957,414...23,961,206
Ensembl chr22:23,957,414...23,961,195
G
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GUCY1A1 mRNA
CTD
PMID:23196670
NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059
G
GUSB
glucuronidase beta
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of GUSB mRNA
CTD
PMID:37080397
NCBI chr 7:65,960,684...65,982,213
Ensembl chr 7:65,960,684...65,982,215
G
GYPC
glycophorin C (Gerbich blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GYPC mRNA
CTD
PMID:23196670
NCBI chr 2:126,656,158...126,696,667
Ensembl chr 2:126,656,133...126,696,667
G
GYS2
glycogen synthase 2
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GYS2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GYS2 mRNA
CTD
PMID:20959002 PMID:37080397
NCBI chr12:21,532,577...21,604,847
Ensembl chr12:21,536,107...21,604,847
G
H2AX
H2A.X variant histone
multiple interactions increases expression
EXP
2,4,3',5'-tetramethoxystilbene inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of H2AX protein]
CTD
PMID:31733235
NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
G
H2BC1
H2B clustered histone 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of H2BC1 mRNA
CTD
PMID:23196670
NCBI chr 6:25,726,777...25,727,345
Ensembl chr 6:25,726,777...25,727,345
G
H6PD
hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of H6PD mRNA
CTD
PMID:23994337
NCBI chr 1:9,234,774...9,271,337
Ensembl chr 1:9,234,774...9,271,337
G
HACL1
2-hydroxyacyl-CoA lyase 1
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of HACL1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HACL1 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 3:15,560,699...15,601,569
Ensembl chr 3:15,560,699...15,601,852
G
HAL
histidine ammonia-lyase
multiple interactions decreases expression increases expression
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of HAL mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HAL mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HAL mRNA
CTD
PMID:16984957 PMID:19692669 PMID:20959002 PMID:23994337
NCBI chr12:95,972,662...95,996,344
Ensembl chr12:95,972,662...95,996,365
G
HAMP
hepcidin antimicrobial peptide
decreases expression decreases response to substance multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HAMP mRNA HAMP protein results in decreased susceptibility to 3,4,5,3',4'-pentachlorobiphenyl [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of HAMP mRNA
CTD
PMID:25686467 PMID:30744511
NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
G
HAP1
huntingtin associated protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HAP1 mRNA
CTD
PMID:32119087
NCBI chr17:41,717,739...41,734,646
Ensembl chr17:41,717,742...41,734,644
G
HAS2
hyaluronan synthase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HAS2 mRNA
CTD
PMID:32119087
NCBI chr 8:121,612,116...121,641,440
Ensembl chr 8:121,612,116...121,641,440
G
HAT1
histone acetyltransferase 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HAT1 mRNA
CTD
PMID:37080397
NCBI chr 2:171,922,461...171,983,686
Ensembl chr 2:171,922,448...171,983,686
G
HAUS4
HAUS augmin like complex subunit 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HAUS4 mRNA
CTD
PMID:23196670
NCBI chr14:22,946,228...22,957,090
Ensembl chr14:22,946,228...22,957,161
G
HAVCR2
hepatitis A virus cellular receptor 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HAVCR2 mRNA
CTD
PMID:32119087
NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869
G
HBA2
hemoglobin subunit alpha 2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of HBA-A3 mRNA
CTD
PMID:30744511
NCBI chr16:172,876...173,710
Ensembl chr16:172,876...173,710
G
HBEGF
heparin binding EGF like growth factor
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HBEGF mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603
G
HDAC1
histone deacetylase 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HDAC1 mRNA
CTD
PMID:37080397
NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635
G
HDAC3
histone deacetylase 3
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HDAC3 mRNA
CTD
PMID:37080397
NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849
G
HDAC4
histone deacetylase 4
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HDAC4 mRNA
CTD
PMID:37080397
NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654
G
HDAC9
histone deacetylase 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HDAC9 mRNA
CTD
PMID:32119087
NCBI chr 7:18,086,825...19,002,416
Ensembl chr 7:18,086,949...19,002,416
G
HDC
histidine decarboxylase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HDC mRNA
CTD
PMID:20959002
NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965
G
HELZ2
helicase with zinc finger 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HELZ2 mRNA
CTD
PMID:32119087
NCBI chr20:63,558,086...63,574,239
Ensembl chr20:63,558,086...63,574,239
G
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HERC6 mRNA
CTD
PMID:32119087
NCBI chr 4:88,378,852...88,443,097
Ensembl chr 4:88,378,739...88,443,097
G
HES1
hes family bHLH transcription factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HES1 mRNA
CTD
PMID:23196670
NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
G
HEXIM2
HEXIM P-TEFb complex subunit 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HEXIM2 mRNA
CTD
PMID:32119087
NCBI chr17:45,160,174...45,170,040
Ensembl chr17:45,160,700...45,170,040
G
HGF
hepatocyte growth factor
affects expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HGF mRNA
CTD
PMID:21703328 PMID:37080397
NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438
G
HIC1
HIC ZBTB transcriptional repressor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HIC1 mRNA
CTD
PMID:32119087
NCBI chr17:2,055,103...2,063,241
Ensembl chr17:2,054,154...2,063,241
G
HIF1A
hypoxia inducible factor 1 subunit alpha
affects localization affects expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the localization of HIF1A protein 3,4,5,3',4'-pentachlorobiphenyl affects the expression of HIF1A mRNA
CTD
PMID:24916446 PMID:37080397
NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
G
HIGD1A
HIG1 hypoxia inducible domain family member 1A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HIGD1A mRNA
CTD
PMID:23196670
NCBI chr 3:42,782,908...42,804,490
Ensembl chr 3:42,782,908...42,804,490
G
HIPK2
homeodomain interacting protein kinase 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HIPK2 mRNA
CTD
PMID:23146750
NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
G
HIVEP2
HIVEP zinc finger 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HIVEP2 mRNA
CTD
PMID:23196670
NCBI chr 6:142,751,469...142,946,365
Ensembl chr 6:142,751,469...142,956,698
G
HK2
hexokinase 2
increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HK2 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HK2 mRNA]
CTD
PMID:34256052 PMID:35618242
NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359
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HKDC1
hexokinase domain containing 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HKDC1 mRNA
CTD
PMID:23146750
NCBI chr10:69,220,332...69,267,552
Ensembl chr10:69,220,332...69,267,552
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HLA-DPB2
major histocompatibility complex, class II, DP beta 2 (pseudogene)
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HLA-DPB2 mRNA
CTD
PMID:23146750
NCBI chr 6:33,112,516...33,129,113
Ensembl chr 6:33,112,516...33,129,084
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HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RT1-BB mRNA
CTD
PMID:20959002
NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
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HLA-DRA
major histocompatibility complex, class II, DR alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RT1-DA mRNA
CTD
PMID:20959002
NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046
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HMGB2
high mobility group box 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMGB2 mRNA
CTD
PMID:23196670
NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432
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HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMGCR mRNA
CTD
PMID:20574914 PMID:23196670
NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
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HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMGCS1 mRNA
CTD
PMID:23196670
NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512
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HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2
decreases expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMGCS2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMGCS2 mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMGCS2 mRNA]
CTD
PMID:23196670 PMID:26396156 PMID:32119087 PMID:34848246
NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
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HMGN3
high mobility group nucleosomal binding domain 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMGN3 mRNA
CTD
PMID:32119087
NCBI chr 6:79,201,245...79,234,682
Ensembl chr 6:79,201,245...79,234,689
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HMOX1
heme oxygenase 1
affects expression multiple interactions increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HMOX1 mRNA [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of HMOX1 mRNA; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 protein]]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMOX1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMOX1 mRNA [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMOX1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 protein
CTD
PMID:21703328 PMID:28163111 PMID:30768972 PMID:35618242 PMID:37598416
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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HNF4A
hepatocyte nuclear factor 4 alpha
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HNF4A mRNA
CTD
PMID:20959002
NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845
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HOXB2
homeobox B2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HOXB2 mRNA
CTD
PMID:20959002
NCBI chr17:48,542,655...48,545,109
Ensembl chr17:48,540,894...48,545,109
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HOXB9
homeobox B9
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HOXB9 mRNA
CTD
PMID:23146750
NCBI chr17:48,621,156...48,626,358
Ensembl chr17:48,621,156...48,626,358
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HPD
4-hydroxyphenylpyruvate dioxygenase
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of HPD mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HPD mRNA
CTD
PMID:16984957 PMID:23196670
NCBI chr12:121,839,527...121,888,611
Ensembl chr12:121,839,527...121,863,596
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HS3ST1
heparan sulfate-glucosamine 3-sulfotransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HS3ST1 mRNA
CTD
PMID:23196670
NCBI chr 4:11,393,150...11,434,327
Ensembl chr 4:11,393,150...11,429,564
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HSD11B1
hydroxysteroid 11-beta dehydrogenase 1
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD11B1 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
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HSD11B2
hydroxysteroid 11-beta dehydrogenase 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSD11B2 mRNA
CTD
PMID:23146750
NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
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HSD17B1
hydroxysteroid 17-beta dehydrogenase 1
decreases expression increases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSD17B1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B1 mRNA]
CTD
PMID:25433332 PMID:34256052
NCBI chr17:42,552,923...42,555,214
Ensembl chr17:42,552,922...42,555,214
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HSD17B2
hydroxysteroid 17-beta dehydrogenase 2
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B2 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B2 mRNA]
CTD
PMID:19692669 PMID:34256052
NCBI chr16:82,035,253...82,098,534
Ensembl chr16:82,035,004...82,098,534
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HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B3 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B3 mRNA]
CTD
PMID:34256052
NCBI chr 9:96,235,306...96,302,176
Ensembl chr 9:96,235,306...96,302,176
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HSD17B7
hydroxysteroid 17-beta dehydrogenase 7
decreases expression increases expression multiple interactions decreases methylation
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSD17B7 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 mRNA 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased methylation of HSD17B7 promoter
CTD
PMID:20959002 PMID:23196670 PMID:27663891
NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823
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HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD3B2 mRNA
CTD
PMID:16216300 PMID:20574914
NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035
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HSDL2
hydroxysteroid dehydrogenase like 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSDL2 mRNA
CTD
PMID:19692669
NCBI chr 9:112,380,108...112,472,405
Ensembl chr 9:112,380,080...112,472,405
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HSP90AB1
heat shock protein 90 alpha family class B member 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HSP90AB1 mRNA
CTD
PMID:21703328
NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
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HSPA4L
heat shock protein family A (Hsp70) member 4 like
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSPA4L mRNA
CTD
PMID:23994337
NCBI chr 4:127,781,796...127,840,733
Ensembl chr 4:127,781,821...127,840,733
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HSPA5
heat shock protein family A (Hsp70) member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSPA5 mRNA
CTD
PMID:37080397
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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HSPA8
heat shock protein family A (Hsp70) member 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSPA8 mRNA
CTD
PMID:32119087
NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
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HSPB1
heat shock protein family B (small) member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSPB1 mRNA
CTD
PMID:23196670
NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
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HSPB2
heat shock protein family B (small) member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSPB2 mRNA
CTD
PMID:23196670
NCBI chr11:111,912,734...111,914,093
Ensembl chr11:111,912,734...111,914,093
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HTR2B
5-hydroxytryptamine receptor 2B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HTR2B mRNA
CTD
PMID:23196670
NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042
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HYAL1
hyaluronidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HYAL1 mRNA
CTD
PMID:23196670
NCBI chr 3:50,299,893...50,312,381
Ensembl chr 3:50,299,890...50,312,381
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ICAM1
intercellular adhesion molecule 1
increases expression multiple interactions increases secretion affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ICAM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ICAM1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ICAM1 protein]; [perfluorooctane sulfonic acid co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of ICAM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of ICAM1 protein alternative form 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ICAM1 mRNA
CTD
PMID:20959002 PMID:22262711 PMID:26519613 PMID:28973532 PMID:29216392 PMID:33096110 PMID:35618242 PMID:37080397 More...
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
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ICAM5
intercellular adhesion molecule 5
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ICAM5 mRNA
CTD
PMID:23146750
NCBI chr19:10,289,952...10,296,778
Ensembl chr19:10,289,952...10,296,778
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ICOSLG
inducible T cell costimulator ligand
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ICOSLG mRNA
CTD
PMID:32119087
NCBI chr21:44,216,981...44,240,943
Ensembl chr21:44,215,382...44,241,446
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ID1
inhibitor of DNA binding 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ID1 mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515
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ID2
inhibitor of DNA binding 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ID2 mRNA
CTD
PMID:23196670
NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
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ID4
inhibitor of DNA binding 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ID4 mRNA
CTD
PMID:23196670
NCBI chr 6:19,837,370...19,842,197
Ensembl chr 6:19,837,370...19,842,197
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IDE
insulin degrading enzyme
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of IDE mRNA
CTD
PMID:37080397
NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096
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IDH2
isocitrate dehydrogenase (NADP(+)) 2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of IDH2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IDH2 mRNA
CTD
PMID:16984957
NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477
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IDI1
isopentenyl-diphosphate delta isomerase 1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IDI1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IDI1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119
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IER3
immediate early response 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IER3 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:32119087
NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548
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IFI44
interferon induced protein 44
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IFI44 mRNA
CTD
PMID:32119087
NCBI chr 1:78,649,789...78,664,078
Ensembl chr 1:78,649,796...78,664,078
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IFI44L
interferon induced protein 44 like
decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IFI44L mRNA
CTD
PMID:23146750 PMID:32119087
NCBI chr 1:78,620,448...78,646,145
Ensembl chr 1:78,619,902...78,646,145
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IFNG
interferon gamma
increases secretion multiple interactions decreases secretion decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IFNG protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL2 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL3 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL4 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMOX1 mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NFE2L2 mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of IFNG protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IFNG mRNA
CTD
PMID:29216392 PMID:30768972 PMID:31563530
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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IGF1
insulin like growth factor 1
multiple interactions decreases expression increases expression affects expression
ISO
[2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of IGF1 protein; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of IGF1 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGF1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IGF1 mRNA
CTD
PMID:19327374 PMID:19692669 PMID:23196670 PMID:30312631 PMID:31820026 PMID:34848246 PMID:37080397 More...
NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
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IGF1R
insulin like growth factor 1 receptor
decreases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1R mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IGF1R mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
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IGF2R
insulin like growth factor 2 receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF2R mRNA
CTD
PMID:23196670
NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507
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IGFBP1
insulin like growth factor binding protein 1
increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGFBP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IGFBP1 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:37080397
NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
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IGFBP2
insulin like growth factor binding protein 2
decreases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IGFBP2 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436
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IGFBP3
insulin like growth factor binding protein 3
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGFBP3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGFBP3 protein
CTD
PMID:10919282 PMID:22262711
NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
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IGFBP4
insulin like growth factor binding protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP4 mRNA
CTD
PMID:23196670
NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725
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IGFBP5
insulin like growth factor binding protein 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP5 mRNA
CTD
PMID:23196670
NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
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IGFBP6
insulin like growth factor binding protein 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP6 mRNA
CTD
PMID:23196670
NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345
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IGFBP7
insulin like growth factor binding protein 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP7 mRNA
CTD
PMID:23196670
NCBI chr 4:57,030,773...57,110,385
Ensembl chr 4:57,030,773...57,110,385
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IGLON5
IgLON family member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGLON5 mRNA
CTD
PMID:32119087
NCBI chr19:51,311,644...51,330,891
Ensembl chr19:51,311,644...51,330,891
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IGSF8
immunoglobulin superfamily member 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGSF8 mRNA
CTD
PMID:23196670
NCBI chr 1:160,091,339...160,099,468
Ensembl chr 1:160,091,340...160,098,943
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IHH
Indian hedgehog signaling molecule
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IHH mRNA
CTD
PMID:32119087
NCBI chr 2:219,054,424...219,060,921
Ensembl chr 2:219,054,424...219,060,921
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IKBKB
inhibitor of nuclear factor kappa B kinase subunit beta
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of IKBKB mRNA
CTD
PMID:37080397
NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460
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IL10
interleukin 10
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of IL10 mRNA; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 protein
CTD
PMID:23196670 PMID:28973532 PMID:37598416
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
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IL11
interleukin 11
multiple interactions
ISO
[AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of IL11 mRNA
CTD
PMID:34256052
NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463
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IL11RA
interleukin 11 receptor subunit alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL11RA1 mRNA
CTD
PMID:23196670
NCBI chr 9:34,652,185...34,661,902
Ensembl chr 9:34,652,162...34,661,902
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IL12A
interleukin 12A
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of [IL12A protein binds to IL12B protein]
CTD
PMID:29216392
NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
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IL12B
interleukin 12B
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of [IL12A protein binds to IL12B protein]
CTD
PMID:29216392
NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
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IL13
interleukin 13
increases secretion
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL13 protein
CTD
PMID:29216392
NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
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IL15
interleukin 15
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL15 mRNA
CTD
PMID:28351761
NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987
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IL17RB
interleukin 17 receptor B
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL17RB mRNA
CTD
PMID:19692669
NCBI chr 3:53,846,568...53,865,794
Ensembl chr 3:53,846,568...53,865,794
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IL17RE
interleukin 17 receptor E
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL17RE mRNA
CTD
PMID:23196670
NCBI chr 3:9,902,093...9,916,402
Ensembl chr 3:9,902,612...9,916,402
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IL18
interleukin 18
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of IL18 mRNA
CTD
PMID:21703328
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
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IL1A
interleukin 1 alpha
increases expression affects expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1A mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IL1A mRNA
CTD
PMID:26519613 PMID:28351761 PMID:35618242 PMID:37080397
NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
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IL1B
interleukin 1 beta
multiple interactions decreases expression increases expression increases secretion
EXP ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL1B protein]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL1B mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B protein Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B protein]
CTD
PMID:22262711 PMID:25433332 PMID:26519613 PMID:28351761 PMID:29216392 PMID:30768972 PMID:35618242 PMID:37080397 PMID:37598416 More...
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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IL1R1
interleukin 1 receptor type 1
increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1R1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL1R1 mRNA
CTD
PMID:20959002 PMID:32119087 PMID:34256052 PMID:35618242
NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874
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IL1RAP
interleukin 1 receptor accessory protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL1RAP mRNA
CTD
PMID:23196670
NCBI chr 3:190,514,085...190,659,750
Ensembl chr 3:190,514,051...190,659,750
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IL1RL1
interleukin 1 receptor like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1RL1 mRNA
CTD
PMID:23196670
NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037
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IL1RN
interleukin 1 receptor antagonist
increases expression multiple interactions increases secretion
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1RN mRNA 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL1RN protein]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1RN mRNA]
CTD
PMID:22262711 PMID:28351761 PMID:30768972
NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
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IL2
interleukin 2
decreases expression decreases secretion
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of IL2 protein
CTD
PMID:31563530
NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
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IL24
interleukin 24
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL24 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL24 protein
CTD
PMID:28351761
NCBI chr 1:206,897,443...206,904,139
Ensembl chr 1:206,897,443...206,904,139
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IL33
interleukin 33
multiple interactions decreases expression increases expression
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of IL33 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL33 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL33 mRNA
CTD
PMID:16984957 PMID:20959002 PMID:34256052 PMID:35618242
NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983
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IL34
interleukin 34
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL34 mRNA
CTD
PMID:32119087 PMID:35618242
NCBI chr16:70,579,899...70,660,682
Ensembl chr16:70,579,895...70,660,682
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IL37
interleukin 37
affects expression decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of IL37 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL37 mRNA
CTD
PMID:21703328 PMID:23146750
NCBI chr 2:112,911,165...112,918,882
Ensembl chr 2:112,911,165...112,918,882
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IL4R
interleukin 4 receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL4RA mRNA
CTD
PMID:23196670
NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
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IL5
interleukin 5
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL5 mRNA
CTD
PMID:28351761
NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
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IL6
interleukin 6
increases expression multiple interactions increases secretion
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA; [aroclor 1260 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of IL6 mRNA; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein] 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL6 protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 mRNA]; KDM4B protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; lipoxin A4 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL6 protein]
CTD
PMID:19265715 PMID:26519613 PMID:27663891 PMID:28351761 PMID:28973532 PMID:30312631 PMID:30768972 PMID:33026256 PMID:35618242 PMID:37598416 More...
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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IL6ST
interleukin 6 cytokine family signal transducer
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6ST mRNA
CTD
PMID:34256052
NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022
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IMPA2
inositol monophosphatase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IMPA2 mRNA
CTD
PMID:20959002
NCBI chr18:11,981,507...12,030,877
Ensembl chr18:11,981,025...12,030,877
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INHBB
inhibin subunit beta B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INHBB mRNA
CTD
PMID:32119087
NCBI chr 2:120,346,136...120,351,803
Ensembl chr 2:120,346,136...120,351,803
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INHBE
inhibin subunit beta E
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INHBE mRNA
CTD
PMID:23196670
NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280
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INPP5B
inositol polyphosphate-5-phosphatase B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of INPP5B mRNA
CTD
PMID:32119087
NCBI chr 1:37,860,697...37,947,057
Ensembl chr 1:37,860,697...37,947,053
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INS-IGF2
INS-IGF2 readthrough
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of INS1 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INS1 mRNA]
CTD
PMID:30312631
NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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INSIG1
insulin induced gene 1
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INSIG1 mRNA
CTD
PMID:23146750 PMID:23196670 PMID:29216392
NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235
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INSL6
insulin like 6
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of INSL6 mRNA
CTD
PMID:20702594
NCBI chr 9:4,991,976...5,185,639
Ensembl chr 9:5,123,880...5,185,647
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INSR
insulin receptor
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of INSR mRNA
CTD
PMID:37080397
NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414
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INTS12
integrator complex subunit 12
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INTS12 mRNA
CTD
PMID:23196670
NCBI chr 4:105,682,627...105,708,689
Ensembl chr 4:105,682,627...105,895,986
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IRAK1
interleukin 1 receptor associated kinase 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IRAK1 mRNA
CTD
PMID:35618242
NCBI chr X:154,010,507...154,019,902
Ensembl chr X:154,010,506...154,019,902
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IRF1
interferon regulatory factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IRF1 mRNA
CTD
PMID:23196670
NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
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IRF7
interferon regulatory factor 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IRF7 mRNA
CTD
PMID:32119087
NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983
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IRF9
interferon regulatory factor 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IRF9 mRNA
CTD
PMID:23196670
NCBI chr14:24,161,265...24,166,565
Ensembl chr14:24,161,234...24,168,043
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IRS1
insulin receptor substrate 1
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IRS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IRS1 mRNA
CTD
PMID:20959002 PMID:35618242 PMID:37080397
NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820
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IRS2
insulin receptor substrate 2
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of IRS2 mRNA
CTD
PMID:37080397
NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583
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ISG20
interferon stimulated exonuclease gene 20
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ISG20 mRNA
CTD
PMID:23196670
NCBI chr15:88,635,632...88,656,483
Ensembl chr15:88,635,670...88,656,483
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ISL1
ISL LIM homeobox 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ISL1 mRNA
CTD
PMID:23196670
NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730
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ITGA1
integrin subunit alpha 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITGA1 mRNA
CTD
PMID:23196670
NCBI chr 5:52,787,916...52,959,209
Ensembl chr 5:52,787,916...52,959,209
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ITGA2B
integrin subunit alpha 2b
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITGA2B mRNA
CTD
PMID:20959002
NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649
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ITGA7
integrin subunit alpha 7
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ITGA7 mRNA
CTD
PMID:16984957
NCBI chr12:55,684,568...55,716,400
Ensembl chr12:55,684,568...55,716,404
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ITGA8
integrin subunit alpha 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITGA8 mRNA
CTD
PMID:32119087
NCBI chr10:15,513,954...15,719,922
Ensembl chr10:15,513,954...15,719,922
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ITGB5
integrin subunit beta 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ITGB5 mRNA
CTD
PMID:23196670
NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418
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ITGB8
integrin subunit beta 8
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ITGB8 mRNA
CTD
PMID:35618242
NCBI chr 7:20,329,766...20,415,754
Ensembl chr 7:20,330,702...20,415,754
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ITIH4
inter-alpha-trypsin inhibitor heavy chain 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITIH4 mRNA
CTD
PMID:23196670
NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688
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ITPR1
inositol 1,4,5-trisphosphate receptor type 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITPR1 mRNA
CTD
PMID:20959002
NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
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ITPR3
inositol 1,4,5-trisphosphate receptor type 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITPR3 mRNA
CTD
PMID:23196670
NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
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ITSN1
intersectin 1
decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITSN1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ITSN1 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr21:33,642,501...33,899,861
Ensembl chr21:33,642,400...33,899,861
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JAM3
junctional adhesion molecule 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of JAM3 mRNA
CTD
PMID:23196670
NCBI chr11:134,069,072...134,152,001
Ensembl chr11:134,069,071...134,152,001
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JDP2
Jun dimerization protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JDP2 mRNA
CTD
PMID:23196670
NCBI chr14:75,426,943...75,474,107
Ensembl chr14:75,427,716...75,474,111
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JMJD6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JMJD6 mRNA
CTD
PMID:23196670
NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,799
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JOSD1
Josephin domain containing 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JOSD1 mRNA
CTD
PMID:23994337
NCBI chr22:38,685,543...38,701,403
Ensembl chr22:38,685,543...38,701,556
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JPT2
Jupiter microtubule associated homolog 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JPT2 mRNA
CTD
PMID:23196670
NCBI chr16:1,678,279...1,702,086
Ensembl chr16:1,678,256...1,702,280
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JUN
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JUN mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JUN protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of JUN mRNA
CTD
PMID:16081525 PMID:19692669 PMID:20959002
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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JUND
JunD proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JUND mRNA
CTD
PMID:23196670
NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622
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JUP
junction plakoglobin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of JUP mRNA
CTD
PMID:23196670
NCBI chr17:41,754,609...41,786,711
Ensembl chr17:41,754,604...41,786,931
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KCND3
potassium voltage-gated channel subfamily D member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KCND3 mRNA
CTD
PMID:23196670
NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668
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KCNH2
potassium voltage-gated channel subfamily H member 2
affects activity
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the activity of KCNH2 protein
CTD
PMID:22676973
NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
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KCNIP1
potassium voltage-gated channel interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNIP1 mRNA
CTD
PMID:32119087
NCBI chr 5:170,353,487...170,736,632
Ensembl chr 5:170,353,487...170,736,632
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KCNJ12
potassium inwardly rectifying channel subfamily J member 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KCNJ12 mRNA
CTD
PMID:23196670
NCBI chr17:21,376,357...21,419,870
Ensembl chr17:21,376,357...21,419,870
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KCNJ2
potassium inwardly rectifying channel subfamily J member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNJ2 mRNA
CTD
PMID:23196670
NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
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KCNJ5
potassium inwardly rectifying channel subfamily J member 5
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KCNJ5 mRNA
CTD
PMID:23146750
NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
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KCNK1
potassium two pore domain channel subfamily K member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNK1 mRNA
CTD
PMID:23196670
NCBI chr 1:233,614,106...233,672,514
Ensembl chr 1:233,614,106...233,672,514
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KCNMB1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KCNMB1 mRNA
CTD
PMID:32119087
NCBI chr 5:170,374,671...170,389,367
Ensembl chr 5:170,374,671...170,389,634
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KCNS1
potassium voltage-gated channel modifier subfamily S member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNS1 mRNA
CTD
PMID:32119087
NCBI chr20:45,091,214...45,101,127
Ensembl chr20:45,091,214...45,101,127
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KCNV1
potassium voltage-gated channel modifier subfamily V member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNV1 mRNA
CTD
PMID:23196670
NCBI chr 8:109,963,636...109,975,771
Ensembl chr 8:109,963,636...109,975,771
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KDM4B
lysine demethylase 4B
multiple interactions increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to KDM4B intron]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [KDM4B protein binds to RELA promoter]; ESR1 protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KDM4B mRNA]; KDM4B protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; KDM4B protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA]
CTD
PMID:26519613
NCBI chr19:4,969,113...5,153,598
Ensembl chr19:4,969,113...5,153,598
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KEAP1
kelch like ECH associated protein 1
decreases expression multiple interactions affects expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KEAP1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of KEAP1 protein] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of KEAP1 mRNA
CTD
PMID:24709675 PMID:31563530
NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
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KHK
ketohexokinase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KHK mRNA
CTD
PMID:20959002
NCBI chr 2:27,086,772...27,100,762
Ensembl chr 2:27,086,772...27,100,762
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KIF15
kinesin family member 15
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KIF15 mRNA
CTD
PMID:23196670
NCBI chr 3:44,761,794...44,868,687
Ensembl chr 3:44,761,721...44,873,376
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KIF22
kinesin family member 22
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KIF22 mRNA
CTD
PMID:23196670
NCBI chr16:29,790,751...29,805,385
Ensembl chr16:29,790,727...29,805,385
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KIFC1
kinesin family member C1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KIFC1 mRNA
CTD
PMID:23196670
NCBI chr 6:33,391,461...33,409,896
Ensembl chr 6:33,391,823...33,409,896
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KIFC2
kinesin family member C2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KIFC2 mRNA
CTD
PMID:23196670
NCBI chr 8:144,466,049...144,474,202
Ensembl chr 8:144,466,043...144,474,202
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KIR2DL4
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KIR2DL4 mRNA
CTD
PMID:23146750
NCBI chr19:54,803,610...54,814,517
Ensembl chr19:54,803,610...54,814,517
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KIR2DL5A
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KIR2DL5A mRNA
CTD
PMID:23146750
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KITLG
KIT ligand
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KITL mRNA
CTD
PMID:23196670
NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851
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KL
klotho
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in increased expression of KL mRNA
CTD
PMID:31820026
NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143
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KLC4
kinesin light chain 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLC4 mRNA
CTD
PMID:32119087
NCBI chr 6:43,059,631...43,075,093
Ensembl chr 6:43,040,777...43,075,095
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KLF10
KLF transcription factor 10
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLF10 mRNA
CTD
PMID:23196670
NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725
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KLF6
KLF transcription factor 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLF6 mRNA
CTD
PMID:23196670
NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281
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KLHL3
kelch like family member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLHL3 mRNA
CTD
PMID:32119087
NCBI chr 5:137,617,500...137,736,089
Ensembl chr 5:137,617,500...137,736,089
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KLRG1
killer cell lectin like receptor G1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLRG1 mRNA
CTD
PMID:20959002
NCBI chr12:8,950,044...9,215,570
Ensembl chr12:8,950,044...9,010,760
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KMO
kynurenine 3-monooxygenase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KMO mRNA
CTD
PMID:20959002
NCBI chr 1:241,532,378...241,595,642
Ensembl chr 1:241,532,134...241,595,642
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KNSTRN
kinetochore localized astrin (SPAG5) binding protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KNSTRN mRNA
CTD
PMID:23196670
NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288
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KPNA6
karyopherin subunit alpha 6
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KPNA6 mRNA
CTD
PMID:23994337
NCBI chr 1:32,108,056...32,176,563
Ensembl chr 1:32,108,056...32,176,563
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KRT10
keratin 10
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of KRT10 protein
CTD
PMID:23457121
NCBI chr17:40,818,117...40,822,614
Ensembl chr17:40,818,117...40,822,614
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KRT14
keratin 14
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KRT14 mRNA
CTD
PMID:23196670
NCBI chr17:41,582,279...41,586,895
Ensembl chr17:41,582,279...41,586,895
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KRT15
keratin 15
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KRT15 mRNA
CTD
PMID:23196670
NCBI chr17:41,513,745...41,518,890
Ensembl chr17:41,513,745...41,522,529
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KRT18
keratin 18
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KRT18 mRNA
CTD
PMID:32119087
NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906
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KRT19
keratin 19
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KRT19 mRNA
CTD
PMID:23196670
NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308
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KRT76
keratin 76
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KRT76 mRNA
CTD
PMID:32119087
NCBI chr12:52,768,155...52,777,345
Ensembl chr12:52,768,155...52,777,345
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KYNU
kynureninase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KYNU mRNA
CTD
PMID:19692669
NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
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L3HYPDH
trans-L-3-hydroxyproline dehydratase
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of L3HYPDH mRNA
CTD
PMID:16984957
NCBI chr14:59,465,478...59,505,273
Ensembl chr14:59,460,363...59,484,408
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LAMA1
laminin subunit alpha 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LAMA1 mRNA
CTD
PMID:32119087
NCBI chr18:6,941,742...7,117,797
Ensembl chr18:6,941,742...7,117,797
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LAMB2
laminin subunit beta 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LAMB2 mRNA
CTD
PMID:23196670
NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118
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LANCL1
LanC like glutathione S-transferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LANCL1 mRNA
CTD
PMID:23196670
NCBI chr 2:210,431,251...210,477,584
Ensembl chr 2:210,427,131...210,477,652
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LAPTM4B
lysosomal protein transmembrane 4 beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LAPTM4B mRNA
CTD
PMID:23196670
NCBI chr 8:97,775,788...97,853,013
Ensembl chr 8:97,775,057...97,853,013
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LARGE1
LARGE xylosyl- and glucuronyltransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LARGE1 mRNA
CTD
PMID:32119087
NCBI chr22:33,066,663...33,922,824
Ensembl chr22:33,162,226...33,922,841
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LBP
lipopolysaccharide binding protein
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LBP mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LBP mRNA
CTD
PMID:19692669 PMID:20959002 PMID:23196670
NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013
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LBR
lamin B receptor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LBR mRNA
CTD
PMID:23196670
NCBI chr 1:225,401,502...225,428,821
Ensembl chr 1:225,401,502...225,428,925
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LCN2
lipocalin 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LCN2 mRNA
CTD
PMID:20959002
NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
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LDHA
lactate dehydrogenase A
increases expression decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LDHA mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LDHA mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LDHA mRNA]
CTD
PMID:23196670 PMID:29474705 PMID:30821169 PMID:34256052 PMID:37080397
NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425
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LDHAL6B
lactate dehydrogenase A like 6B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LDHAL6B mRNA
CTD
PMID:23196670
NCBI chr15:59,206,843...59,208,588
Ensembl chr15:59,206,843...59,208,588
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LDHB
lactate dehydrogenase B
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of LDHB mRNA
CTD
PMID:37080397
NCBI chr12:21,635,342...21,657,842
Ensembl chr12:21,635,342...21,757,857
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LDLR
low density lipoprotein receptor
increases expression increases response to substance
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LDLR mRNA LDLR gene mutant form results in increased susceptibility to 3,4,5,3',4'-pentachlorobiphenyl
CTD
PMID:23196670 PMID:29216392 PMID:35618242
NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
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LEF1
lymphoid enhancer binding factor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LEF1 mRNA
CTD
PMID:23196670
NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
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LEP
leptin
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of LEP protein
CTD
PMID:28973532
NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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LETM2
leucine zipper and EF-hand containing transmembrane protein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LETM2 mRNA
CTD
PMID:23196670
NCBI chr 8:38,382,431...38,409,527
Ensembl chr 8:38,386,207...38,409,527
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LGALS3
galectin 3
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LGALS3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LGALS3 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423
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LGI4
leucine rich repeat LGI family member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LGI4 mRNA
CTD
PMID:23196670
NCBI chr19:35,124,513...35,135,059
Ensembl chr19:35,124,513...35,142,451
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LGMN
legumain
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LGMN mRNA
CTD
PMID:23196670
NCBI chr14:92,703,809...92,748,627
Ensembl chr14:92,703,807...92,748,679
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LHB
luteinizing hormone subunit beta
multiple interactions
ISO
[AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in increased secretion of LHB protein
CTD
PMID:34256052
NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091
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LHPP
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of LHPP mRNA
CTD
PMID:20702594
NCBI chr10:124,461,823...124,614,141
Ensembl chr10:124,461,823...124,617,888
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LIF
LIF interleukin 6 family cytokine
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LIF mRNA
CTD
PMID:28351761 PMID:35618242
NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
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LIFR
LIF receptor subunit alpha
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LIFR mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 5:38,474,668...38,608,403
Ensembl chr 5:38,474,668...38,608,354
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LIG1
DNA ligase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LIG1 mRNA
CTD
PMID:23196670
NCBI chr19:48,115,445...48,170,344
Ensembl chr19:48,115,445...48,170,603
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LILRB5
leukocyte immunoglobulin like receptor B5
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LILRB5 mRNA
CTD
PMID:23146750
NCBI chr19:54,249,421...54,257,273
Ensembl chr19:54,249,421...54,257,301
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LIMK1
LIM domain kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LIMK1 mRNA
CTD
PMID:23196670
NCBI chr 7:74,083,804...74,122,525
Ensembl chr 7:74,082,933...74,122,525
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LIMK2
LIM domain kinase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LIMK2 mRNA
CTD
PMID:19692669
NCBI chr22:31,212,298...31,280,080
Ensembl chr22:31,212,239...31,280,080
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LIPA
lipase A, lysosomal acid type
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LIP1 mRNA
CTD
PMID:23196670
NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557
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LIPE
lipase E, hormone sensitive type
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LIPE mRNA
CTD
PMID:23196670
NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,514...42,427,388
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LMCD1
LIM and cysteine rich domains 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LMCD1 mRNA
CTD
PMID:23196670
NCBI chr 3:8,501,823...8,574,668
Ensembl chr 3:8,501,807...8,574,668
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LMNB1
lamin B1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LMNB1 mRNA
CTD
PMID:23196670
NCBI chr 5:126,776,623...126,837,020
Ensembl chr 5:126,776,623...126,837,020
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LMO4
LIM domain only 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LMO4 mRNA
CTD
PMID:23196670
NCBI chr 1:87,328,880...87,348,923
Ensembl chr 1:87,328,880...87,348,923
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LMO7
LIM domain 7
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LMO7 mRNA
CTD
PMID:23196670
NCBI chr13:75,620,434...75,859,870
Ensembl chr13:75,620,434...75,859,870
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LNPEP
leucyl and cystinyl aminopeptidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LNPEP mRNA
CTD
PMID:23196670
NCBI chr 5:96,936,080...97,037,513
Ensembl chr 5:96,935,394...97,037,513
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LOX
lysyl oxidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LOX mRNA
CTD
PMID:23196670
NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413
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LOXL1
lysyl oxidase like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LOXL1 mRNA
CTD
PMID:20959002
NCBI chr15:73,926,462...73,952,136
Ensembl chr15:73,925,989...73,952,137
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LPAR1
lysophosphatidic acid receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LPAR1 mRNA
CTD
PMID:23196670
NCBI chr 9:110,873,263...111,038,998
Ensembl chr 9:110,873,263...111,038,470
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LPIN1
lipin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPIN1 mRNA
CTD
PMID:23196670
NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
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LPIN2
lipin 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPIN2 mRNA
CTD
PMID:23994337
NCBI chr18:2,916,994...3,013,144
Ensembl chr18:2,885,296...3,013,144
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LPL
lipoprotein lipase
increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPL mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LPL mRNA
CTD
PMID:20959002 PMID:23196670 PMID:29216392 PMID:29947894 PMID:32119087
NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
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LPO
lactoperoxidase
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPO mRNA]
CTD
PMID:34256052
NCBI chr17:58,238,584...58,268,518
Ensembl chr17:58,218,548...58,268,518
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LRFN1
leucine rich repeat and fibronectin type III domain containing 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LRFN1 mRNA
CTD
PMID:23146750
NCBI chr19:39,306,566...39,320,863
Ensembl chr19:39,306,566...39,320,863
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LRFN3
leucine rich repeat and fibronectin type III domain containing 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LRFN3 mRNA
CTD
PMID:32119087
NCBI chr19:35,936,374...35,946,624
Ensembl chr19:35,935,358...35,946,624
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LRP1
LDL receptor related protein 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of LRP1 mRNA
CTD
PMID:37080397
NCBI chr12:57,128,483...57,213,361
Ensembl chr12:57,128,483...57,213,361
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LRP2
LDL receptor related protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LRP2 mRNA
CTD
PMID:23994337
NCBI chr 2:169,127,109...169,362,534
Ensembl chr 2:169,127,109...169,362,534
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LRP4
LDL receptor related protein 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LRP4 mRNA
CTD
PMID:23196670
NCBI chr11:46,856,717...46,918,550
Ensembl chr11:46,856,717...46,918,642
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LRRFIP1
LRR binding FLII interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LRRFIP1 mRNA
CTD
PMID:23196670
NCBI chr 2:237,627,587...237,781,643
Ensembl chr 2:237,627,587...237,813,682
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LSS
lanosterol synthase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LSS mRNA
CTD
PMID:23196670
NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824
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LTB
lymphotoxin beta
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LTB mRNA
CTD
PMID:28351761
NCBI chr 6:31,580,558...31,582,425
Ensembl chr 6:31,580,525...31,582,522
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LTB4R2
leukotriene B4 receptor 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LTB4R2 mRNA
CTD
PMID:23146750
NCBI chr14:24,310,140...24,312,038
Ensembl chr14:24,305,734...24,312,053
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LTBP1
latent transforming growth factor beta binding protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LTBP1 mRNA
CTD
PMID:23196670
NCBI chr 2:32,946,953...33,399,509
Ensembl chr 2:32,946,953...33,399,509
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LTF
lactotransferrin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LTF mRNA
CTD
PMID:32119087
NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
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LYAR
Ly1 antibody reactive
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LYAR mRNA
CTD
PMID:23196670
NCBI chr 4:4,267,701...4,290,154
Ensembl chr 4:4,267,701...4,290,154
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LYN
LYN proto-oncogene, Src family tyrosine kinase
affects expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of LYN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LYN mRNA
CTD
PMID:20702594 PMID:23196670
NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169
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LYPD1
LY6/PLAUR domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LYPD1 mRNA
CTD
PMID:23196670
NCBI chr 2:132,643,286...132,671,526
Ensembl chr 2:132,643,286...132,671,579
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LYPLA1
lysophospholipase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LYPLA1 mRNA
CTD
PMID:23196670
NCBI chr 8:54,046,367...54,101,947
Ensembl chr 8:54,046,367...54,102,017
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LYZ
lysozyme
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LYZ mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LYZ mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234
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LYZL1
lysozyme like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LYZL1 mRNA
CTD
PMID:23994337
NCBI chr10:29,289,070...29,318,328
Ensembl chr10:29,289,061...29,318,328
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MAB21L3
mab-21 like 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAB21L3 mRNA
CTD
PMID:32119087
NCBI chr 1:116,111,399...116,138,149
Ensembl chr 1:116,111,399...116,138,149
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MAF
MAF bZIP transcription factor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAF mRNA
CTD
PMID:23196670
NCBI chr16:79,202,622...79,600,737
Ensembl chr16:79,585,843...79,600,737
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MAFF
MAF bZIP transcription factor F
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAFF mRNA
CTD
PMID:19692669
NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507
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MAGEE1
MAGE family member E1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAGEE1 mRNA
CTD
PMID:23146750
NCBI chr X:76,427,710...76,431,342
Ensembl chr X:76,427,710...76,431,342
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MALT1
MALT1 paracaspase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MALT1 mRNA
CTD
PMID:32119087
NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477
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MAOA
monoamine oxidase A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAOA mRNA
CTD
PMID:19692669
NCBI chr X:43,655,006...43,746,817
Ensembl chr X:43,654,907...43,746,817
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MAOB
monoamine oxidase B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAOB mRNA
CTD
PMID:19692669
NCBI chr X:43,766,610...43,882,450
Ensembl chr X:43,766,610...43,882,450
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MAPK1
mitogen-activated protein kinase 1
increases phosphorylation multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of MAPK1 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD
PMID:19751709 PMID:20406653 PMID:20840854 PMID:29329451
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK3
mitogen-activated protein kinase 3
increases phosphorylation multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of MAPK3 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD
PMID:19751709 PMID:20406653 PMID:20840854 PMID:29329451
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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MAPKAPK3
MAPK activated protein kinase 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAPKAPK3 mRNA
CTD
PMID:23196670
NCBI chr 3:50,611,520...50,649,291
Ensembl chr 3:50,611,520...50,649,291
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MAPKAPK5
MAPK activated protein kinase 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAPKAPK5 mRNA
CTD
PMID:23994337
NCBI chr12:111,842,228...111,902,222
Ensembl chr12:111,842,013...111,902,222
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MARCKS
myristoylated alanine rich protein kinase C substrate
decreases expression increases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MARCKS mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MARCKS mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MARCKS mRNA]
CTD
PMID:19692669 PMID:34256052
NCBI chr 6:113,857,345...113,863,475
Ensembl chr 6:113,857,345...113,863,475
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MARCO
macrophage receptor with collagenous structure
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MARCO mRNA
CTD
PMID:23146750
NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660
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MASP1
MBL associated serine protease 1
decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MASP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MASP1 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr 3:187,217,282...187,291,737
Ensembl chr 3:187,217,282...187,291,980
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MAT2B
methionine adenosyltransferase 2 non-catalytic beta subunit
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAT2B mRNA
CTD
PMID:23994337
NCBI chr 5:163,503,064...163,519,354
Ensembl chr 5:163,503,114...163,519,558
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MAVS
mitochondrial antiviral signaling protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAVS mRNA
CTD
PMID:32119087
NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
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MB21D2
Mab-21 domain containing 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MB21D2 mRNA
CTD
PMID:29947894
NCBI chr 3:192,796,815...192,917,856
Ensembl chr 3:192,796,815...192,917,856
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MBL2
mannose binding lectin 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MBL2 mRNA
CTD
PMID:19692669
NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
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MC2R
melanocortin 2 receptor
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MC2R mRNA [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of MC2R mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of MC2R mRNA
CTD
PMID:25765474
NCBI chr18:13,882,044...13,915,707
Ensembl chr18:13,882,044...13,915,707
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MCAM
melanoma cell adhesion molecule
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MCAM mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr11:119,308,529...119,317,130
Ensembl chr11:119,308,529...119,321,521
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MCCC1
methylcrotonyl-CoA carboxylase subunit 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MCCC1 mRNA
CTD
PMID:19692669
NCBI chr 3:183,015,218...183,116,196
Ensembl chr 3:183,015,218...183,116,075
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MCF2L
MCF.2 cell line derived transforming sequence like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MCF2L mRNA
CTD
PMID:32119087
NCBI chr13:112,894,335...113,099,742
Ensembl chr13:112,894,378...113,099,742
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MCM3AP
minichromosome maintenance complex component 3 associated protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MCM3AP mRNA
CTD
PMID:23994337
NCBI chr21:46,235,133...46,286,265
Ensembl chr21:46,235,133...46,286,297
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MDFI
MyoD family inhibitor
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MDFI mRNA
CTD
PMID:23146750
NCBI chr 6:41,637,018...41,654,244
Ensembl chr 6:41,636,882...41,654,244
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MDM2
MDM2 proto-oncogene
multiple interactions increases phosphorylation
EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein]; MDM2 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of FOXO3 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of MDM2 protein
CTD
PMID:19751709 PMID:20840854
NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
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ME1
malic enzyme 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ME1 mRNA
CTD
PMID:20959002
NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
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ME3
malic enzyme 3
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ME3 mRNA
CTD
PMID:23146750
NCBI chr11:86,434,930...86,672,616
Ensembl chr11:86,441,108...86,672,636
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MED1
mediator complex subunit 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of MED1 mRNA
CTD
PMID:20702594
NCBI chr17:39,404,285...39,451,263
Ensembl chr17:39,404,285...39,451,272
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MET
MET proto-oncogene, receptor tyrosine kinase
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MET mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MET mRNA
CTD
PMID:23146750 PMID:23196670 PMID:37080397
NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377
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MFAP4
microfibril associated protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MFAP4 mRNA
CTD
PMID:23994337
NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190
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MFAP5
microfibril associated protein 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MFAP5 mRNA
CTD
PMID:32119087
NCBI chr12:8,645,943...8,662,826
Ensembl chr12:8,637,346...8,662,888
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MGAT1
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MGAT1 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 5:180,784,780...180,815,616
Ensembl chr 5:180,784,780...180,815,652
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MGAT3
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGAT3 mRNA
CTD
PMID:23196670
NCBI chr22:39,457,012...39,492,194
Ensembl chr22:39,457,012...39,492,194
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MGLL
monoglyceride lipase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGLL mRNA
CTD
PMID:23196670
NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190
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MGP
matrix Gla protein
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MGP mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGP mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr12:14,880,864...14,885,854
Ensembl chr12:14,880,864...14,885,857
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MGST1
microsomal glutathione S-transferase 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MGST1 mRNA
CTD
PMID:21703328
NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259
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MGST2
microsomal glutathione S-transferase 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGST2 mRNA
CTD
PMID:23146750
NCBI chr 4:139,665,819...139,754,618
Ensembl chr 4:139,665,768...139,740,745
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MGST3
microsomal glutathione S-transferase 3
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of MGST3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGST3 mRNA
CTD
PMID:16984957 PMID:18723825 PMID:19692669 PMID:20959002
NCBI chr 1:165,631,234...165,656,136
Ensembl chr 1:165,631,213...165,661,796
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MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MICAL2 mRNA
CTD
PMID:23196670
NCBI chr11:12,110,590...12,362,140
Ensembl chr11:12,094,008...12,359,144
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MID1IP1
MID1 interacting protein 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MID1IP1 mRNA
CTD
PMID:23146750
NCBI chr X:38,801,459...38,806,532
Ensembl chr X:38,801,440...38,806,537
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MIOS
meiosis regulator for oocyte development
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MIOS mRNA
CTD
PMID:23994337
NCBI chr 7:7,566,884...7,609,144
Ensembl chr 7:7,566,875...7,608,932
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MKLN1
muskelin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MKLN1 mRNA
CTD
PMID:32119087
NCBI chr 7:131,110,094...131,496,632
Ensembl chr 7:131,110,096...131,496,632
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MMD
monocyte to macrophage differentiation associated
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MMD mRNA
CTD
PMID:23196670
NCBI chr17:55,392,622...55,421,835
Ensembl chr17:55,392,622...55,421,924
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MME
membrane metalloendopeptidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MME mRNA
CTD
PMID:23196670
NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704
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MMP1
matrix metallopeptidase 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP1 mRNA
CTD
PMID:35618242
NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
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MMP11
matrix metallopeptidase 11
decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MMP11 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr22:23,772,849...23,784,316
Ensembl chr22:23,768,226...23,784,316
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MMP12
matrix metallopeptidase 12
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP12 mRNA
CTD
PMID:20959002
NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
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MMP14
matrix metallopeptidase 14
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MMP14 mRNA
CTD
PMID:23196670
NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
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MMP2
matrix metallopeptidase 2
increases secretion increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of MMP2 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP2 mRNA
CTD
PMID:27663891 PMID:29947894 PMID:35618242
NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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MMP23B
matrix metallopeptidase 23B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MMP23 mRNA
CTD
PMID:23994337
NCBI chr 1:1,632,173...1,634,654
Ensembl chr 1:1,632,163...1,635,263
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MMP3
matrix metallopeptidase 3
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP3 mRNA
CTD
PMID:35618242
NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
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MMP9
matrix metallopeptidase 9
affects expression increases secretion increases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of MMP9 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of MMP9 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP9 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of MMP9 protein]
CTD
PMID:21703328 PMID:27663891 PMID:28973532
NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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MOGAT1
monoacylglycerol O-acyltransferase 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of MOGAT1 mRNA
CTD
PMID:28973532
NCBI chr 2:222,671,658...222,709,930
Ensembl chr 2:222,671,658...222,709,930
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MPO
myeloperoxidase
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MPO mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MPO mRNA]
CTD
PMID:34256052
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
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MPP7
MAGUK p55 scaffold protein 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MPP7 mRNA
CTD
PMID:32119087
NCBI chr10:28,050,993...28,335,203
Ensembl chr10:28,050,993...28,334,486
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MPPED2
metallophosphoesterase domain containing 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MPPED2 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr11:30,384,079...30,586,993
Ensembl chr11:30,384,493...30,586,872
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MRPL37
mitochondrial ribosomal protein L37
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MRPL37 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr 1:54,200,167...54,225,489
Ensembl chr 1:54,184,041...54,225,464
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MRPS24
mitochondrial ribosomal protein S24
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MRPS24 mRNA
CTD
PMID:23994337
NCBI chr 7:43,866,558...43,869,517
Ensembl chr 7:43,866,558...43,869,893
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MS4A14
membrane spanning 4-domains A14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MS4A14 mRNA
CTD
PMID:32119087
NCBI chr11:60,396,459...60,417,756
Ensembl chr11:60,378,530...60,417,756
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MS4A4A
membrane spanning 4-domains A4A
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MS4A4A mRNA
CTD
PMID:23146750
NCBI chr11:60,280,666...60,308,970
Ensembl chr11:60,185,657...60,318,080
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MS4A6A
membrane spanning 4-domains A6A
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MS4A6A mRNA
CTD
PMID:23146750
NCBI chr11:60,171,607...60,184,666
Ensembl chr11:60,172,015...60,184,666
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MS4A7
membrane spanning 4-domains A7
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MS4A7 mRNA
CTD
PMID:32119087
NCBI chr11:60,378,532...60,395,948
Ensembl chr11:60,378,485...60,395,951
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MSMO1
methylsterol monooxygenase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MSMO1 mRNA
CTD
PMID:23196670
NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164
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MSR1
macrophage scavenger receptor 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MSR1 mRNA
CTD
PMID:23146750
NCBI chr 8:16,107,881...16,192,651
Ensembl chr 8:16,107,878...16,567,490
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MT1A
metallothionein 1A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MT1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MT1A mRNA
CTD
PMID:26410179 PMID:26660635 PMID:26967026
NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087
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MT1X
metallothionein 1X
multiple interactions affects response to substance
ISO
[MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA; [MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Copper; [MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Manganese; [MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Zinc
CTD
PMID:26770886
NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
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MT2A
metallothionein 2A
increases expression affects response to substance multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MT2A mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MT2A protein MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA; [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Copper; [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Manganese; [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Zinc
CTD
PMID:23527585 PMID:26410179 PMID:26770886 PMID:26967026
NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
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MTHFR
methylenetetrahydrofolate reductase
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MTHFR mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MTHFR mRNA]
CTD
PMID:34256052
NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
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MTMR7
myotubularin related protein 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MTMR7 mRNA
CTD
PMID:20959002
NCBI chr 8:17,296,794...17,413,351
Ensembl chr 8:17,296,794...17,413,528
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MTOR
mechanistic target of rapamycin kinase
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of MTOR mRNA
CTD
PMID:37080397
NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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MTTP
microsomal triglyceride transfer protein
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of MTTP mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MTTP protein
CTD
PMID:26693162 PMID:28973532
NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
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MVD
mevalonate diphosphate decarboxylase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MVD mRNA
CTD
PMID:23196670
NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161
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MX1
MX dynamin like GTPase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MX1 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071
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MX2
MX dynamin like GTPase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MX2 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr21:41,362,027...41,409,393
Ensembl chr21:41,361,999...41,409,393
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MXRA8
matrix remodeling associated 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MXRA8 mRNA
CTD
PMID:23196670
NCBI chr 1:1,352,689...1,363,541
Ensembl chr 1:1,352,689...1,361,777
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MYH10
myosin heavy chain 10
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MYH10 mRNA
CTD
PMID:23196670
NCBI chr17:8,474,212...8,630,725
Ensembl chr17:8,474,207...8,631,376
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MYL1
myosin light chain 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MYL1 mRNA
CTD
PMID:32119087
NCBI chr 2:210,290,150...210,315,174
Ensembl chr 2:210,290,150...210,315,174
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MYL11
myosin light chain 11
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MYLPF mRNA
CTD
PMID:32119087
NCBI chr16:30,370,934...30,377,991
Ensembl chr16:30,370,934...30,377,991
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MYL9
myosin light chain 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MYL9 mRNA
CTD
PMID:19692669
NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447
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MYOF
myoferlin
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MYOF mRNA
CTD
PMID:19692669
NCBI chr10:93,306,429...93,482,334
Ensembl chr10:93,306,429...93,482,334
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MYOZ2
myozenin 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MYOZ2 mRNA
CTD
PMID:23994337
NCBI chr 4:119,135,832...119,187,789
Ensembl chr 4:119,135,832...119,187,789
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NAAA
N-acylethanolamine acid amidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NAAA mRNA
CTD
PMID:23196670
NCBI chr 4:75,910,655...75,941,013
Ensembl chr 4:75,913,660...75,941,013
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NAMPT
nicotinamide phosphoribosyltransferase
multiple interactions decreases expression increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NAMPT mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NAMPT mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NAMPT mRNA
CTD
PMID:16984957 PMID:20959002 PMID:37080397
NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966
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NAT8
N-acetyltransferase 8 (putative)
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of NAT8 mRNA
CTD
PMID:30744511
NCBI chr 2:73,640,723...73,642,422
Ensembl chr 2:73,640,723...73,642,422
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NAV2
neuron navigator 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NAV2 mRNA
CTD
PMID:32119087
NCBI chr11:19,345,236...20,121,601
Ensembl chr11:19,350,724...20,121,601
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NCAM1
neural cell adhesion molecule 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NCAM1 mRNA
CTD
PMID:23196670
NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436
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NCF1
neutrophil cytosolic factor 1
increases localization multiple interactions increases phosphorylation increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased localization of NCF1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [NCF1 protein binds to CYBB protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [NCF1 protein modified form binds to CYBB protein]; acetovanillone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of NCF1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NCF1 mRNA
CTD
PMID:20299304 PMID:23146750 PMID:30821169
NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
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NCF4
neutrophil cytosolic factor 4
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NCF4 mRNA
CTD
PMID:30821169
NCBI chr22:36,861,006...36,878,015
Ensembl chr22:36,860,988...36,878,017
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NDRG4
NDRG family member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NDRG4 mRNA
CTD
PMID:23196670
NCBI chr16:58,463,715...58,515,387
Ensembl chr16:58,462,846...58,513,628
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NDUFB9
NADH:ubiquinone oxidoreductase subunit B9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NDUFB9 mRNA
CTD
PMID:19692669
NCBI chr 8:124,539,123...124,549,979
Ensembl chr 8:124,539,101...124,580,648
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NEDD4L
NEDD4 like E3 ubiquitin protein ligase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NEDD4L mRNA
CTD
PMID:23196670
NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
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NEFH
neurofilament heavy chain
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NEFH mRNA
CTD
PMID:23146750
NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390
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NEURL3
neuralized E3 ubiquitin protein ligase 3
increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NEURL3 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of LINCR mRNA
CTD
PMID:19692669 PMID:20702594
NCBI chr 2:96,497,646...96,508,109
Ensembl chr 2:96,497,646...96,508,109
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NFE2L2
NFE2 like bZIP transcription factor 2
increases expression multiple interactions affects expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NFE2L2 mRNA [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NFE2L2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of NFE2L2 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [perfluorooctane sulfonic acid results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein]]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein
CTD
PMID:23196670 PMID:24378064 PMID:26770886 PMID:30768972 PMID:31563530 PMID:33096110 PMID:37080397 PMID:37598416 More...
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NFIA
nuclear factor I A
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFIA mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NFIA mRNA
CTD
PMID:20959002 PMID:32119087
NCBI chr 1:61,077,227...61,462,788
Ensembl chr 1:60,865,259...61,462,788
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NFIX
nuclear factor I X
affects expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of NFIX mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFIX mRNA
CTD
PMID:20959002 PMID:21703328
NCBI chr19:12,995,475...13,098,796
Ensembl chr19:12,995,475...13,098,796
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NGF
nerve growth factor
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NGF mRNA
CTD
PMID:35618242
NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
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NGFR
nerve growth factor receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NGFR mRNA
CTD
PMID:23196670
NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008
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NHERF1
NHERF family PDZ scaffold protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NHERF1 mRNA
CTD
PMID:23196670
NCBI chr17:74,748,628...74,769,353
Ensembl chr17:74,748,628...74,769,353
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NID2
nidogen 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NID2 mRNA
CTD
PMID:23196670
NCBI chr14:52,004,809...52,069,059
Ensembl chr14:52,004,809...52,069,059
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NIPAL2
NIPA like domain containing 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NIPAL2 mRNA
CTD
PMID:20959002
NCBI chr 8:98,189,826...98,294,235
Ensembl chr 8:98,189,826...98,294,393
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NKX6-1
NK6 homeobox 1
multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of NKX6-1 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NKX6-1 mRNA]
CTD
PMID:30312631
NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292
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NMT2
N-myristoyltransferase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NMT2 mRNA
CTD
PMID:23196670
NCBI chr10:15,105,700...15,168,693
Ensembl chr10:15,102,584...15,168,693
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NOL3
nucleolar protein 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NOL3 mRNA
CTD
PMID:23196670
NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737
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NOMO3
NODAL modulator 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOMO1 mRNA
CTD
PMID:23994337
NCBI chr16:16,232,528...16,294,811
Ensembl chr16:16,232,506...16,300,806
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NOP58
NOP58 ribonucleoprotein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOL5 mRNA
CTD
PMID:23196670
NCBI chr 2:202,265,763...202,303,661
Ensembl chr 2:202,265,736...202,303,661
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NOS2
nitric oxide synthase 2
affects expression multiple interactions increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of NOS2 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOS2 mRNA]
CTD
PMID:21703328 PMID:34256052
NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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NOS3
nitric oxide synthase 3
multiple interactions
EXP
[Estradiol co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of NOS3 mRNA
CTD
PMID:21513769
NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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NOTCH1
notch receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOTCH1 mRNA
CTD
PMID:18042819 PMID:20702594 PMID:23994337
NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
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NOX1
NADPH oxidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NOX1 mRNA
CTD
PMID:32119087
NCBI chr X:100,843,324...100,874,359
Ensembl chr X:100,843,324...100,874,359
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NOX4
NADPH oxidase 4
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOX4 mRNA
CTD
PMID:32119087 PMID:35618242
NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
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NPHP1
nephrocystin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPHP1 mRNA
CTD
PMID:23994337
NCBI chr 2:110,123,348...110,205,013
Ensembl chr 2:110,122,311...110,205,066
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NPL
N-acetylneuraminate pyruvate lyase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NPL mRNA
CTD
PMID:23196670
NCBI chr 1:182,789,773...182,830,384
Ensembl chr 1:182,789,293...182,830,384
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NPPB
natriuretic peptide B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPPB mRNA
CTD
PMID:23196670
NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
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NPR1
natriuretic peptide receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NPR1 mRNA
CTD
PMID:23196670
NCBI chr 1:153,678,688...153,693,992
Ensembl chr 1:153,678,688...153,693,992
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NPR3
natriuretic peptide receptor 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NPR3 mRNA
CTD
PMID:23196670
NCBI chr 5:32,690,872...32,791,720
Ensembl chr 5:32,689,070...32,791,724
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NPTX1
neuronal pentraxin 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPTX1 mRNA
CTD
PMID:22262711
NCBI chr17:80,466,834...80,476,607
Ensembl chr17:80,466,834...80,477,843
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NPTXR
neuronal pentraxin receptor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPTXR mRNA
CTD
PMID:23196670
NCBI chr22:38,818,452...38,844,028
Ensembl chr22:38,818,452...38,844,028
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NPY4R
neuropeptide Y receptor Y4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPY4R mRNA
CTD
PMID:32119087
NCBI chr10:46,461,099...46,470,668
Ensembl chr10:46,461,099...46,465,958
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NQO1
NAD(P)H quinone dehydrogenase 1
increases expression multiple interactions decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NQO1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of NQO1 mRNA; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein]]; CAV1 gene mutant form promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein]; Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA]; Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 protein] [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA] AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein
CTD
PMID:17627975 PMID:18042819 PMID:19692669 PMID:20702594 PMID:20959002 PMID:22262711 PMID:23196670 PMID:23994337 PMID:24378064 PMID:24709675 PMID:26770886 PMID:28163111 PMID:30768972 PMID:32119087 PMID:33096110 PMID:34256052 PMID:37080397 PMID:37598416 More...
NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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NR0B2
nuclear receptor subfamily 0 group B member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NR0B2 mRNA
CTD
PMID:20959002
NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975
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NR1H4
nuclear receptor subfamily 1 group H member 4
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NR1H4 mRNA
CTD
PMID:19692669
NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
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NR1I2
nuclear receptor subfamily 1 group I member 2
multiple interactions decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of NR1I2 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NR1I2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NR1I2 mRNA
CTD
PMID:30312631 PMID:37080397
NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
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NR1I3
nuclear receptor subfamily 1 group I member 3
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NR1I3 mRNA [aroclor 1260 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of NR1I3 mRNA
CTD
PMID:17627975 PMID:30312631
NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
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NR3C1
nuclear receptor subfamily 3 group C member 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of NR3C1 mRNA
CTD
PMID:37080397
NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
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NR4A1
nuclear receptor subfamily 4 group A member 1
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of NR4A1 mRNA]
CTD
PMID:30312631
NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507
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NR4A3
nuclear receptor subfamily 4 group A member 3
multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of NR4A3 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NR4A3 mRNA]
CTD
PMID:30312631
NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891
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NRG1
neuregulin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NRG1 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:23196670
NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
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NRGN
neurogranin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NRGN mRNA
CTD
PMID:23196670
NCBI chr11:124,739,942...124,747,210
Ensembl chr11:124,739,942...124,747,210
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NRM
nurim
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NRM mRNA
CTD
PMID:23196670
NCBI chr 6:30,688,049...30,691,420
Ensembl chr 6:30,688,047...30,691,420
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NRP2
neuropilin 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NRP2 mRNA
CTD
PMID:23146750
NCBI chr 2:205,682,501...205,798,131
Ensembl chr 2:205,681,990...205,798,133
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NSDHL
NAD(P) dependent steroid dehydrogenase-like
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NSDHL mRNA
CTD
PMID:23196670
NCBI chr X:152,831,063...152,869,729
Ensembl chr X:152,830,967...152,869,729
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NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NSMF mRNA
CTD
PMID:32119087
NCBI chr 9:137,447,570...137,459,334
Ensembl chr 9:137,447,570...137,459,334
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NT5E
5'-nucleotidase ecto
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NT5E mRNA
CTD
PMID:23196670
NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791
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NTF3
neurotrophin 3
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NTF3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NTF3 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr12:5,430,332...5,495,299
Ensembl chr12:5,432,108...5,521,536
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NTN4
netrin 4
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NTN4 mRNA
CTD
PMID:29947894
NCBI chr12:95,657,807...95,791,155
Ensembl chr12:95,657,807...95,791,189
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NTRK1
neurotrophic receptor tyrosine kinase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NTRK1 mRNA
CTD
PMID:20959002
NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850
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NTRK2
neurotrophic receptor tyrosine kinase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NTRK2 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751
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NUF2
NUF2 component of NDC80 kinetochore complex
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NUF2 mRNA
CTD
PMID:23196670
NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764
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NUPR1
nuclear protein 1, transcriptional regulator
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NUPR1 mRNA
CTD
PMID:19692669
NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008
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NXPE1
neurexophilin and PC-esterase domain family member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NXPE1 mRNA
CTD
PMID:32119087
NCBI chr11:114,518,934...114,559,881
Ensembl chr11:114,518,934...114,559,881
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NXPH4
neurexophilin 4
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NXPH4 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NXPH4 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr12:57,216,794...57,226,449
Ensembl chr12:57,216,794...57,226,449
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OAS1
2'-5'-oligoadenylate synthetase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OAS1 mRNA
CTD
PMID:23196670
NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219
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OASL
2'-5'-oligoadenylate synthetase like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OASL1 mRNA
CTD
PMID:23196670
NCBI chr12:121,017,761...121,039,246
Ensembl chr12:121,017,763...121,039,246
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OCLN
occludin
multiple interactions decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [TJP1 protein binds to OCLN protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OCLN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN protein
CTD
PMID:20064788 PMID:20299304 PMID:23196670 PMID:37598416
NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
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OLFML1
olfactomedin like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OLFML1 mRNA
CTD
PMID:23196670
NCBI chr11:7,485,506...7,511,377
Ensembl chr11:7,485,388...7,511,377
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OPLAH
5-oxoprolinase, ATP-hydrolysing
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OPLAH mRNA
CTD
PMID:23196670
NCBI chr 8:144,050,322...144,063,961
Ensembl chr 8:144,051,266...144,063,965
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OPTN
optineurin
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OPTN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OPTN mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308
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OR10A5
olfactory receptor family 10 subfamily A member 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OR10A5 mRNA
CTD
PMID:23196670
NCBI chr11:6,845,683...6,846,636
Ensembl chr11:6,845,683...6,846,636
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OR14C36
olfactory receptor family 14 subfamily C member 36
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OR14C39B mRNA
CTD
PMID:23196670
NCBI chr 1:248,348,775...248,349,713
Ensembl chr 1:248,348,775...248,349,713
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OR2A1
olfactory receptor family 2 subfamily A member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OR2A51 mRNA
CTD
PMID:23196670
NCBI chr 7:144,312,079...144,322,737
Ensembl chr 7:144,312,419...144,322,737
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OR2D2
olfactory receptor family 2 subfamily D member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OR2D2 mRNA
CTD
PMID:23196670
NCBI chr11:6,891,574...6,892,500
Ensembl chr11:6,891,574...6,892,500
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ORC1
origin recognition complex subunit 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ORC1 mRNA
CTD
PMID:23196670
NCBI chr 1:52,372,829...52,409,503
Ensembl chr 1:52,372,829...52,404,423
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ORM1
orosomucoid 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ORM1 mRNA
CTD
PMID:21703328
NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479
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OSMR
oncostatin M receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OSMR mRNA
CTD
PMID:23196670
NCBI chr 5:38,846,012...38,945,579
Ensembl chr 5:38,845,858...38,945,596
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OSR2
odd-skipped related transciption factor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OSR2 mRNA
CTD
PMID:23196670
NCBI chr 8:98,944,442...98,952,100
Ensembl chr 8:98,944,403...98,952,104
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OTC
ornithine transcarbamylase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OTC mRNA
CTD
PMID:20959002
NCBI chr X:38,327,684...38,422,928
Ensembl chr X:38,327,598...38,422,908
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OTOP1
otopetrin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OTOP1 mRNA
CTD
PMID:23196670
NCBI chr 4:4,188,726...4,226,929
Ensembl chr 4:4,188,726...4,226,929
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P3H2
prolyl 3-hydroxylase 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of P3H2 mRNA
CTD
PMID:23146750
NCBI chr 3:189,956,728...190,122,278
Ensembl chr 3:189,956,728...190,122,437
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P4HA3
prolyl 4-hydroxylase subunit alpha 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of P4HA3 mRNA
CTD
PMID:23196670
NCBI chr11:74,250,146...74,311,640
Ensembl chr11:74,235,801...74,311,640
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PAK1
p21 (RAC1) activated kinase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PAK1 mRNA
CTD
PMID:23196670
NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635
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PALM
paralemmin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PALM mRNA
CTD
PMID:23196670
NCBI chr19:708,935...748,329
Ensembl chr19:708,935...748,329
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PAPPA2
pappalysin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PAPPA2 mRNA
CTD
PMID:32119087
NCBI chr 1:176,463,175...176,845,601
Ensembl chr 1:176,463,171...176,845,601
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PAQR8
progestin and adipoQ receptor family member 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PAQR8 mRNA
CTD
PMID:23196670
NCBI chr 6:52,362,151...52,407,777
Ensembl chr 6:52,361,421...52,407,777
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PARP1
poly(ADP-ribose) polymerase 1
increases activity multiple interactions increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PARP1 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PARP1 mRNA
CTD
PMID:16884709 PMID:20840854 PMID:23196670
NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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PARP12
poly(ADP-ribose) polymerase family member 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PARP12 mRNA
CTD
PMID:32119087
NCBI chr 7:140,023,749...140,062,951
Ensembl chr 7:140,023,749...140,062,951
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PC
pyruvate carboxylase
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PC mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PC mRNA]
CTD
PMID:20959002 PMID:27509375 PMID:29474705 PMID:34848246
NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386
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PCDHB12
protocadherin beta 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCDHB12 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCDHB19 mRNA
CTD
PMID:23196670
NCBI chr 5:141,208,719...141,212,571
Ensembl chr 5:141,208,697...141,212,571
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PCK1
phosphoenolpyruvate carboxykinase 1
multiple interactions decreases expression increases expression affects expression
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA]; AHR affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of PCK1 mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PCK1 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PCK1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PCK1 mRNA
CTD
PMID:26396156 PMID:27509375 PMID:28163111 PMID:28973532 PMID:29474705 PMID:30312631 PMID:34848246 PMID:37080397 More...
NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
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PCP4L1
Purkinje cell protein 4 like 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PCP4L1 mRNA
CTD
PMID:20702594
NCBI chr 1:161,258,745...161,285,450
Ensembl chr 1:161,258,745...161,285,450
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PCSK4
proprotein convertase subtilisin/kexin type 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PCSK4 mRNA
CTD
PMID:32119087
NCBI chr19:1,481,428...1,490,876
Ensembl chr19:1,481,428...1,490,752
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PCSK5
proprotein convertase subtilisin/kexin type 5
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PCSK5 mRNA
CTD
PMID:19692669
NCBI chr 9:75,889,809...76,362,975
Ensembl chr 9:75,890,644...76,362,975
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PCSK6
proprotein convertase subtilisin/kexin type 6
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCSK6 mRNA
CTD
PMID:23146750
NCBI chr15:101,303,933...101,489,707
Ensembl chr15:101,289,784...101,525,202
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PCYT1A
phosphate cytidylyltransferase 1A, choline
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PCYT1A mRNA
CTD
PMID:32119087
NCBI chr 3:196,234,368...196,287,726
Ensembl chr 3:196,214,222...196,287,957
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PDE3B
phosphodiesterase 3B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDE3B mRNA
CTD
PMID:23196670
NCBI chr11:14,643,804...14,872,044 NCBI chr11:14,887,823...14,899,321
Ensembl chr11:14,643,804...14,872,044
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PDE4B
phosphodiesterase 4B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDE4B mRNA
CTD
PMID:23196670
NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579
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PDE5A
phosphodiesterase 5A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDE5A mRNA
CTD
PMID:23196670
NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804
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PDE7B
phosphodiesterase 7B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDE7B mRNA
CTD
PMID:23196670
NCBI chr 6:135,851,701...136,195,574
Ensembl chr 6:135,851,701...136,195,574
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PDGFA
platelet derived growth factor subunit A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDGFA mRNA
CTD
PMID:23196670
NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296
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PDIA3
protein disulfide isomerase family A member 3
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of PDIA3 protein
CTD
PMID:23457121
NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279
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PDK1
pyruvate dehydrogenase kinase 1
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDK1 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDK1 mRNA]
CTD
PMID:30821169
NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
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PDK2
pyruvate dehydrogenase kinase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDK2 mRNA
CTD
PMID:23196670
NCBI chr17:50,094,737...50,112,152
Ensembl chr17:50,094,737...50,112,152
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PDK4
pyruvate dehydrogenase kinase 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDK4 mRNA
CTD
PMID:23196670
NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
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PDLIM2
PDZ and LIM domain 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDLIM2 mRNA
CTD
PMID:19692669
NCBI chr 8:22,578,741...22,598,026
Ensembl chr 8:22,578,279...22,598,025
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PDP2
pyruvate dehydrogenase phosphatase catalytic subunit 2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of PDP2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDP2 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr16:66,880,515...66,891,101
Ensembl chr16:66,878,589...66,895,754
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PDZD2
PDZ domain containing 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDZD2 mRNA
CTD
PMID:23196670
NCBI chr 5:31,639,131...32,110,932
Ensembl chr 5:31,639,131...32,110,932
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PDZRN3
PDZ domain containing ring finger 3
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PDZRN3 mRNA
CTD
PMID:20702594
NCBI chr 3:73,382,431...73,624,941
Ensembl chr 3:73,382,431...73,624,941
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PECAM1
platelet and endothelial cell adhesion molecule 1
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of PECAM1 protein]
CTD
PMID:28973532
NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776
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PER3
period circadian regulator 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PER3 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 1:7,784,291...7,845,177
Ensembl chr 1:7,784,291...7,845,177
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PF4
platelet factor 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PF4 mRNA
CTD
PMID:34256052
NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027
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PFKL
phosphofructokinase, liver type
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PFKL mRNA
CTD
PMID:23196670
NCBI chr21:44,300,053...44,327,373
Ensembl chr21:44,300,051...44,327,376
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PFN2
profilin 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PFN2 mRNA
CTD
PMID:23146750
NCBI chr 3:149,964,904...149,970,895
Ensembl chr 3:149,964,904...150,050,788
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PGC
progastricsin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PGC mRNA
CTD
PMID:23196670
NCBI chr 6:41,736,711...41,747,397
Ensembl chr 6:41,736,711...41,754,109
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PGK1
phosphoglycerate kinase 1
increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PGK1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PGK1 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr X:78,104,248...78,129,295
Ensembl chr X:77,910,739...78,129,295
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PGPEP1
pyroglutamyl-peptidase I
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of PGPEP1 mRNA
CTD
PMID:30744511
NCBI chr19:18,340,598...18,369,950
Ensembl chr19:18,340,598...18,369,950
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PGR
progesterone receptor
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]
CTD
PMID:26022396
NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813
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PHB1
prohibitin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PHB1 mRNA
CTD
PMID:32119087
NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905
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PHF1
PHD finger protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHF1 mRNA
CTD
PMID:23196670
NCBI chr 6:33,410,412...33,416,439
Ensembl chr 6:33,410,399...33,416,453
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PHGDH
phosphoglycerate dehydrogenase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PHGDH mRNA
CTD
PMID:20959002
NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218
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PHLDA1
pleckstrin homology like domain family A member 1
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PHLDA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHLDA1 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr12:76,025,447...76,031,776
Ensembl chr12:76,025,447...76,031,776
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PHYH
phytanoyl-CoA 2-hydroxylase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHYH mRNA
CTD
PMID:23196670
NCBI chr10:13,277,799...13,300,064
Ensembl chr10:13,277,796...13,302,412
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PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHYHD1 mRNA
CTD
PMID:23196670
NCBI chr 9:128,920,982...128,942,041
Ensembl chr 9:128,920,966...128,942,041
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PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHYHIPL mRNA
CTD
PMID:23196670
NCBI chr10:59,173,597...59,247,770
Ensembl chr10:59,176,643...59,247,774
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PIANP
PILR alpha associated neural protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIANP mRNA
CTD
PMID:23196670
NCBI chr12:6,692,178...6,700,815
Ensembl chr12:6,693,791...6,700,815
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PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIK3C2B mRNA
CTD
PMID:32119087
NCBI chr 1:204,422,633...204,494,805
Ensembl chr 1:204,422,628...204,494,805
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PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIK3C2G mRNA
CTD
PMID:20959002
NCBI chr12:18,242,961...18,726,817
Ensembl chr12:18,242,961...18,648,416
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PIK3IP1
phosphoinositide-3-kinase interacting protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIK3IP1 mRNA
CTD
PMID:23196670
NCBI chr22:31,281,593...31,292,534
Ensembl chr22:31,281,594...31,292,534
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PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIK3R1 mRNA
CTD
PMID:23196670
NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821
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PIK3R3
phosphoinositide-3-kinase regulatory subunit 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PIK3R3 mRNA
CTD
PMID:23196670
NCBI chr 1:46,040,140...46,174,901
Ensembl chr 1:46,040,140...46,133,036
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PKLR
pyruvate kinase L/R
decreases expression multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PKLR mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PKLR mRNA] AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKLR mRNA]
CTD
PMID:28973532 PMID:34256052
NCBI chr 1:155,289,293...155,308,654
Ensembl chr 1:155,289,293...155,301,438
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PKM
pyruvate kinase M1/2
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of and affects the localization of and results in decreased activity of PKM protein; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]
CTD
PMID:28284859 PMID:30821169
NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819
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PLA2G12A
phospholipase A2 group XIIA
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PLA2G12A mRNA
CTD
PMID:20702594
NCBI chr 4:109,709,989...109,730,070
Ensembl chr 4:109,709,989...109,730,070
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PLA2G2C
phospholipase A2 group IIC
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLA2G2C mRNA
CTD
PMID:23994337
NCBI chr 1:20,163,055...20,186,518
Ensembl chr 1:20,161,253...20,186,518
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PLA2G2D
phospholipase A2 group IID
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLA2G2D mRNA
CTD
PMID:23196670
NCBI chr 1:20,111,939...20,119,536
Ensembl chr 1:20,111,939...20,119,566
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PLA2G4A
phospholipase A2 group IVA
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLA2G4A mRNA
CTD
PMID:23994337 PMID:35618242
NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981
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PLA2G4C
phospholipase A2 group IVC
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLA2G4C mRNA
CTD
PMID:32119087
NCBI chr19:48,047,846...48,110,817
Ensembl chr19:48,047,843...48,110,817
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PLAAT1
phospholipase A and acyltransferase 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of HRASLS mRNA
CTD
PMID:30744511
NCBI chr 3:193,240,606...193,281,426
Ensembl chr 3:193,241,128...193,277,738
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PLAGL1
PLAG1 like zinc finger 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLAGL1 mRNA
CTD
PMID:37080397
NCBI chr 6:143,940,300...144,064,599
Ensembl chr 6:143,940,300...144,064,599
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PLAU
plasminogen activator, urokinase
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLAU mRNA
CTD
PMID:35618242
NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
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PLB1
phospholipase B1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLB1 mRNA
CTD
PMID:23146750
NCBI chr 2:28,496,060...28,644,142
Ensembl chr 2:28,457,145...28,644,142
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PLCB1
phospholipase C beta 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLCB1 mRNA
CTD
PMID:32119087
NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360
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PLCB4
phospholipase C beta 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLCB4 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr20:9,068,678...9,480,808
Ensembl chr20:9,067,825...9,504,593
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PLCE1
phospholipase C epsilon 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLCE1 mRNA
CTD
PMID:23196670
NCBI chr10:93,993,931...94,332,823
Ensembl chr10:93,993,931...94,332,823
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PLCL1
phospholipase C like 1 (inactive)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLCL1 mRNA
CTD
PMID:23196670
NCBI chr 2:197,804,593...198,149,863
Ensembl chr 2:197,804,593...198,572,581
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PLEKHA5
pleckstrin homology domain containing A5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLEKHA5 mRNA
CTD
PMID:23196670
NCBI chr12:19,129,733...19,376,400
Ensembl chr12:19,129,669...19,376,400
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PLEKHA6
pleckstrin homology domain containing A6
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLEKHA6 mRNA
CTD
PMID:32119087
NCBI chr 1:204,218,853...204,378,168
Ensembl chr 1:204,218,853...204,378,214
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PLEKHF1
pleckstrin homology and FYVE domain containing 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLEKHF1 mRNA
CTD
PMID:19692669
NCBI chr19:29,665,461...29,675,477
Ensembl chr19:29,665,459...29,675,477
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PLEKHO1
pleckstrin homology domain containing O1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLEKHO1 mRNA
CTD
PMID:23196670
NCBI chr 1:150,149,646...150,160,065
Ensembl chr 1:150,149,183...150,164,720
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PLG
plasminogen
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PLG mRNA
CTD
PMID:21703328
NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
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PLIN2
perilipin 2
multiple interactions affects expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of PLIN2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PLIN2 mRNA
CTD
PMID:16984957 PMID:37080397
NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
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PLK1
polo like kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLK1 mRNA
CTD
PMID:23196670
NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367
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PLLP
plasmolipin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLLP mRNA
CTD
PMID:32119087
NCBI chr16:57,256,097...57,284,672
Ensembl chr16:57,248,547...57,284,672
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PLPP3
phospholipid phosphatase 3
decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLPP3 mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr 1:56,494,761...56,579,563
Ensembl chr 1:56,494,761...56,645,301
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PLSCR4
phospholipid scramblase 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLSCR4 mRNA
CTD
PMID:23196670
NCBI chr 3:146,192,335...146,251,105
Ensembl chr 3:146,192,335...146,251,179
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PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased activity of PMAIP1 protein]
CTD
PMID:20840854
NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305
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PMM1
phosphomannomutase 1
affects expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PMM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PMM1 mRNA
CTD
PMID:20702594 PMID:32119087
NCBI chr22:41,576,900...41,589,840
Ensembl chr22:41,576,900...41,589,871
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PMP22
peripheral myelin protein 22
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PMP22 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PMP22 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr17:15,229,779...15,265,326
Ensembl chr17:15,229,773...15,272,292
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PNPLA3
patatin like phospholipase domain containing 3
multiple interactions decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of PNPLA3 mRNA]; [aroclor 1260 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PNPLA3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PNPLA3 mRNA
CTD
PMID:30312631
NCBI chr22:43,923,805...43,947,582
Ensembl chr22:43,923,792...43,964,488
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PNPLA7
patatin like phospholipase domain containing 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PNPLA7 mRNA
CTD
PMID:23196670
NCBI chr 9:137,459,952...137,550,402
Ensembl chr 9:137,459,952...137,550,402
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PNRC1
proline rich nuclear receptor coactivator 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PNRC1 mRNA
CTD
PMID:20959002
NCBI chr 6:89,080,751...89,085,160
Ensembl chr 6:89,080,751...89,085,160
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PODXL
podocalyxin like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PODXL mRNA
CTD
PMID:23196670
NCBI chr 7:131,500,271...131,556,628
Ensembl chr 7:131,500,262...131,558,217
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POLA2
DNA polymerase alpha 2, accessory subunit
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of POLA2 mRNA
CTD
PMID:23196670
NCBI chr11:65,261,962...65,305,985
Ensembl chr11:65,261,913...65,305,959
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POLD1
DNA polymerase delta 1, catalytic subunit
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of POLD1 mRNA
CTD
PMID:23196670
NCBI chr19:50,384,323...50,418,018
Ensembl chr19:50,384,204...50,418,018
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POLG
DNA polymerase gamma, catalytic subunit
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of POLG mRNA
CTD
PMID:23196670
NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861
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POLG2
DNA polymerase gamma 2, accessory subunit
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of POLG2 mRNA
CTD
PMID:20959002
NCBI chr17:64,477,785...64,497,054
Ensembl chr17:64,477,785...64,497,054
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POLM
DNA polymerase mu
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of POLM mRNA
CTD
PMID:32119087
NCBI chr 7:44,072,062...44,082,530
Ensembl chr 7:44,072,062...44,082,530
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POLR2M
RNA polymerase II subunit M
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GCOM1 mRNA
CTD
PMID:23196670
NCBI chr15:57,706,714...57,717,557
Ensembl chr15:57,706,695...57,782,762
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POMC
proopiomelanocortin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of POMC mRNA
CTD
PMID:32119087
NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
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PON1
paraoxonase 1
decreases expression multiple interactions increases activity increases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PON1 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of PON1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PON1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of and results in increased activity of PON1 protein; Acetylcysteine affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PON1 protein]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA]; Selenic Acid deficiency inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA]; Selenic Acid deficiency promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PON1 protein]; Selenic Acid inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA] 3,3',4,4',5-pentachlorobiphenyl, PCB-126, increases expression of mRNA in rat liver
CTD RGD
PMID:19692669 PMID:22266287 PMID:22653878 PMID:23457121 PMID:23644946 PMID:25530946 PMID:26006071 PMID:34256052 PMID:23644946 More...
RGD:401794573
NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
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PON2
paraoxonase 2
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PON2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON2 mRNA
CTD
PMID:22653878 PMID:23196670 PMID:26006071
NCBI chr 7:95,404,862...95,435,028
Ensembl chr 7:95,404,862...95,435,329
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PON3
paraoxonase 3
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PON3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON3 mRNA
CTD
PMID:22653878 PMID:25530946 PMID:26006071
NCBI chr 7:95,359,872...95,396,375
Ensembl chr 7:95,359,872...95,396,375
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POT1
protection of telomeres 1
multiple interactions decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of POT1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of POT1 mRNA
CTD
PMID:26330309
NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
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PPA1
inorganic pyrophosphatase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPA1 mRNA
CTD
PMID:32119087
NCBI chr10:70,202,835...70,233,429
Ensembl chr10:70,202,835...70,233,911
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PPARA
peroxisome proliferator activated receptor alpha
decreases expression multiple interactions increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARA mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PPARA mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPARA mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PPARA mRNA
CTD
PMID:26396156 PMID:28163111 PMID:28973532 PMID:29474705 PMID:34848246 PMID:37080397 More...
NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
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PPARD
peroxisome proliferator activated receptor delta
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PPARD mRNA
CTD
PMID:37080397
NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191
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PPARG
peroxisome proliferator activated receptor gamma
multiple interactions decreases expression
EXP ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARG mRNA] 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARG mRNA]
CTD
PMID:25304490 PMID:28973532 PMID:35618242
NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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PPARGC1A
PPARG coactivator 1 alpha
decreases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARGC1A mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PPARGC1A mRNA
CTD
PMID:27509375 PMID:37080397
NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
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PPARGC1B
PPARG coactivator 1 beta
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARGC1B mRNA
CTD
PMID:35618242
NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022
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PPEF2
protein phosphatase with EF-hand domain 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPEF2 mRNA
CTD
PMID:32119087
NCBI chr 4:75,859,867...75,902,452
Ensembl chr 4:75,859,864...75,902,571
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PPL
periplakin
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPL mRNA
CTD
PMID:19692669
NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741
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PPOX
protoporphyrinogen oxidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPOX mRNA
CTD
PMID:20959002
NCBI chr 1:161,165,728...161,178,013
Ensembl chr 1:161,166,056...161,178,013
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PPP1R3B
protein phosphatase 1 regulatory subunit 3B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPP1R3B mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 8:9,136,255...9,151,539
Ensembl chr 8:9,136,255...9,151,574
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PPP1R3C
protein phosphatase 1 regulatory subunit 3C
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPP1R3C mRNA
CTD
PMID:23196670
NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071
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PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of PPP2R2B mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPP2R2B mRNA
CTD
PMID:16984957 PMID:23196670
NCBI chr 5:146,580,742...147,081,520
Ensembl chr 5:146,580,742...147,084,784
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PPP2R5E
protein phosphatase 2 regulatory subunit B'epsilon
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPP2R5E mRNA
CTD
PMID:23994337
NCBI chr14:63,371,364...63,543,377
Ensembl chr14:63,371,364...63,543,377
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PPY
pancreatic polypeptide
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPY mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of PPY mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPY mRNA]
CTD
PMID:30312631
NCBI chr17:43,940,804...43,944,215
Ensembl chr17:43,940,804...43,942,476
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PRDM8
PR/SET domain 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRDM8 mRNA
CTD
PMID:32119087
NCBI chr 4:80,185,270...80,204,329
Ensembl chr 4:80,183,879...80,204,329
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PRDX1
peroxiredoxin 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PRDX1 mRNA
CTD
PMID:37080397
NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
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PRELP
proline and arginine rich end leucine rich repeat protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRELP mRNA
CTD
PMID:23196670
NCBI chr 1:203,475,806...203,491,352
Ensembl chr 1:203,475,806...203,491,352
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PRIM1
DNA primase subunit 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRIM1 mRNA
CTD
PMID:23196670
NCBI chr12:56,731,580...56,752,323
Ensembl chr12:56,730,438...56,752,374
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PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein
CTD
PMID:29474705
NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374
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PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRKAA2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of and results in decreased activity of PRKAA2 protein
CTD
PMID:23196670 PMID:29474705
NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335
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PRKAR2A
protein kinase cAMP-dependent type II regulatory subunit alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRKAR2A mRNA
CTD
PMID:32119087
NCBI chr 3:48,744,591...48,847,874
Ensembl chr 3:48,744,597...48,847,874
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PRKCD
protein kinase C delta
increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRKCD mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased phosphorylation of PRKCD protein]
CTD
PMID:20959002 PMID:24709675
NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
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PRLR
prolactin receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRLR mRNA
CTD
PMID:20959002
NCBI chr 5:35,048,756...35,230,487
Ensembl chr 5:35,048,756...35,230,487
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PRNP
prion protein (Kanno blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRNP mRNA
CTD
PMID:23196670
NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590
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PRODH2
proline dehydrogenase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRODH2 mRNA
CTD
PMID:20959002
NCBI chr19:35,799,988...35,812,845
Ensembl chr19:35,799,988...35,813,299
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PRPH
peripherin
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRPH mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRPH mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr12:49,295,147...49,298,686
Ensembl chr12:49,295,147...49,298,686
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PRRX2
paired related homeobox 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRRX2 mRNA
CTD
PMID:32119087
NCBI chr 9:129,665,647...129,722,674
Ensembl chr 9:129,665,647...129,722,674
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PRSS12
serine protease 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRSS12 mRNA
CTD
PMID:23196670
NCBI chr 4:118,280,038...118,353,003
Ensembl chr 4:118,280,038...118,353,003
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PSAT1
phosphoserine aminotransferase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PSAT1 mRNA
CTD
PMID:20959002
NCBI chr 9:78,297,125...78,330,093
Ensembl chr 9:78,297,125...78,330,093
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PSMB8
proteasome 20S subunit beta 8
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PSMB8 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PSMB8 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 6:32,840,717...32,844,679
Ensembl chr 6:32,840,717...32,844,679
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PSMB9
proteasome 20S subunit beta 9
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PSMB9 mRNA
CTD
PMID:23196670
NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851
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PTDSS1
phosphatidylserine synthase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTDSS1 mRNA
CTD
PMID:23196670
NCBI chr 8:96,261,902...96,336,995
Ensembl chr 8:96,261,902...96,336,995
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PTER
phosphotriesterase related
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTER mRNA
CTD
PMID:23196670
NCBI chr10:16,437,010...16,519,020
Ensembl chr10:16,436,943...16,513,745
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PTGER4
prostaglandin E receptor 4
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGER4 mRNA
CTD
PMID:35618242
NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735
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PTGS2
prostaglandin-endoperoxide synthase 2
multiple interactions affects expression increases expression
EXP ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; [Estradiol co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of PTGS2 mRNA; [Estradiol co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of PTGS2 protein; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; Estradiol promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PTGS2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 protein
CTD
PMID:21513769 PMID:21703328 PMID:22262711 PMID:23196670 PMID:35618242
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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PTH
parathyroid hormone
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTH protein
CTD
PMID:31820026
NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181
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PTHLH
parathyroid hormone like hormone
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTHLH mRNA
CTD
PMID:35618242
NCBI chr12:27,958,084...27,972,733
Ensembl chr12:27,958,084...27,972,733
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PTK2B
protein tyrosine kinase 2 beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTK2B mRNA
CTD
PMID:23196670
NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391
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PTMS
parathymosin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTMS mRNA
CTD
PMID:20959002
NCBI chr12:6,766,363...6,770,952
Ensembl chr12:6,765,516...6,770,952
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PTN
pleiotrophin
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTN mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774
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PTPN1
protein tyrosine phosphatase non-receptor type 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTPN1 mRNA
CTD
PMID:23196670
NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241
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PTPN14
protein tyrosine phosphatase non-receptor type 14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTPN14 mRNA
CTD
PMID:32119087
NCBI chr 1:214,348,700...214,551,602
Ensembl chr 1:214,348,700...214,552,449
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PTPN21
protein tyrosine phosphatase non-receptor type 21
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPN21 mRNA
CTD
PMID:20959002
NCBI chr14:88,465,778...88,555,007
Ensembl chr14:88,465,778...88,555,007
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PTPN9
protein tyrosine phosphatase non-receptor type 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPN9 mRNA
CTD
PMID:23196670
NCBI chr15:75,463,251...75,579,315
Ensembl chr15:75,463,251...75,579,315
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PTPRD
protein tyrosine phosphatase receptor type D
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPRD mRNA
CTD
PMID:20959002
NCBI chr 9:8,314,246...10,613,002
Ensembl chr 9:8,314,246...10,613,002
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PTPRF
protein tyrosine phosphatase receptor type F
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPRF mRNA
CTD
PMID:20959002
NCBI chr 1:43,522,051...43,623,666
Ensembl chr 1:43,525,187...43,623,666
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PTPRN
protein tyrosine phosphatase receptor type N
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPRN mRNA
CTD
PMID:20959002
NCBI chr 2:219,289,623...219,309,401
Ensembl chr 2:219,289,623...219,309,648
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PTPRZ1
protein tyrosine phosphatase receptor type Z1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTPRZ1 mRNA
CTD
PMID:23196670
NCBI chr 7:121,873,161...122,062,036
Ensembl chr 7:121,873,089...122,062,036
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PTTG1
PTTG1 regulator of sister chromatid separation, securin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTTG1 mRNA
CTD
PMID:23196670
NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739
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PUS1
pseudouridine synthase 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PUS1 mRNA
CTD
PMID:19692669
NCBI chr12:131,929,276...131,945,896
Ensembl chr12:131,929,200...131,945,896
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PVR
PVR cell adhesion molecule
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PVR mRNA
CTD
PMID:23196670
NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162
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PXK
PX domain containing serine/threonine kinase like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PXK mRNA
CTD
PMID:23196670
NCBI chr 3:58,332,892...58,426,127
Ensembl chr 3:58,332,880...58,426,127
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PYGL
glycogen phosphorylase L
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PYGL mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PYGL mRNA]
CTD
PMID:27509375 PMID:29474705 PMID:34848246
NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483
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RAB30
RAB30, member RAS oncogene family
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAB30 mRNA
CTD
PMID:23196670
NCBI chr11:82,973,133...83,071,897
Ensembl chr11:82,973,133...83,071,923
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RAB3D
RAB3D, member RAS oncogene family
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAB3D mRNA
CTD
PMID:23196670
NCBI chr19:11,322,068...11,339,657
Ensembl chr19:11,322,068...11,346,270
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RAB3IL1
RAB3A interacting protein like 1
decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAB3IL1 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr11:61,897,301...61,946,323
Ensembl chr11:61,897,301...61,920,269
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RAB8B
RAB8B, member RAS oncogene family
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RAB8B mRNA
CTD
PMID:23196670
NCBI chr15:63,189,606...63,267,776
Ensembl chr15:63,189,560...63,267,776
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RAB9A
RAB9A, member RAS oncogene family
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAB9 mRNA
CTD
PMID:23196670
NCBI chr X:13,689,128...13,710,504
Ensembl chr X:13,689,128...13,710,504
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RAF1
Raf-1 proto-oncogene, serine/threonine kinase
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in decreased activity of RAF1 protein
CTD
PMID:20840854
NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201
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RALB
RAS like proto-oncogene B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RALB mRNA
CTD
PMID:20959002
NCBI chr 2:120,240,070...120,294,710
Ensembl chr 2:120,240,064...120,294,710
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RALGDS
ral guanine nucleotide dissociation stimulator
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RALGDS mRNA
CTD
PMID:23196670
NCBI chr 9:133,097,722...133,149,210
Ensembl chr 9:133,097,720...133,149,334
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RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RALGPS1 mRNA
CTD
PMID:32119087
NCBI chr 9:126,914,782...127,223,166
Ensembl chr 9:126,914,774...127,223,166
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RANGAP1
Ran GTPase activating protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RANGAP1 mRNA
CTD
PMID:23196670
NCBI chr22:41,244,779...41,302,369
Ensembl chr22:41,244,779...41,286,187
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RAP2A
RAP2A, member of RAS oncogene family
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAP2A mRNA
CTD
PMID:23196670
NCBI chr13:97,434,169...97,469,128
Ensembl chr13:97,434,169...97,469,128
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RAPGEF2
Rap guanine nucleotide exchange factor 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RAPGEF2 mRNA
CTD
PMID:19692669
NCBI chr 4:159,103,079...159,360,173
Ensembl chr 4:159,103,013...159,360,174
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RARRES2
retinoic acid receptor responder 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RARRES2 mRNA
CTD
PMID:32119087
NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,317...150,341,662
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RASAL1
RAS protein activator like 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RASAL1 mRNA
CTD
PMID:23146750
NCBI chr12:113,099,278...113,136,756
Ensembl chr12:113,098,819...113,136,239
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RASL10B
RAS like family 10 member B
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RASL10B mRNA
CTD
PMID:23146750
NCBI chr17:35,731,639...35,743,521
Ensembl chr17:35,731,639...35,743,521
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RASL11A
RAS like family 11 member A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RASL11A mRNA
CTD
PMID:23196670
NCBI chr13:27,270,830...27,275,192
Ensembl chr13:27,270,830...27,275,192
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RASL11B
RAS like family 11 member B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RASL11B mRNA
CTD
PMID:23196670
NCBI chr 4:52,862,317...52,866,835
Ensembl chr 4:52,862,317...52,866,835
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RASSF9
Ras association domain family member 9
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RASSF9 mRNA
CTD
PMID:23196670
NCBI chr12:85,800,703...85,836,409
Ensembl chr12:85,800,703...85,836,409
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RBBP9
RB binding protein 9, serine hydrolase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RBBP9 mRNA
CTD
PMID:23196670
NCBI chr20:18,486,540...18,497,225
Ensembl chr20:18,486,540...18,497,225
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RBM33
RNA binding motif protein 33
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RBM33 mRNA
CTD
PMID:23994337
NCBI chr 7:155,644,661...155,781,480
Ensembl chr 7:155,644,451...155,781,485
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RBMS1
RNA binding motif single stranded interacting protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RBMS1 mRNA
CTD
PMID:23196670
NCBI chr 2:160,272,151...160,493,807
Ensembl chr 2:160,272,151...160,493,807
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RBP4
retinol binding protein 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RBP4 mRNA
CTD
PMID:23994337
NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744
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RBP7
retinol binding protein 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RBP7 mRNA
CTD
PMID:32119087
NCBI chr 1:9,997,228...10,016,021
Ensembl chr 1:9,997,206...10,016,021
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RCAN1
regulator of calcineurin 1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RCAN1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RCAN1 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr21:34,516,442...34,615,113
Ensembl chr21:34,513,142...34,615,113
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RCAN2
regulator of calcineurin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RCAN2 mRNA
CTD
PMID:23196670
NCBI chr 6:46,220,736...46,491,970
Ensembl chr 6:46,220,736...46,491,972
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RCN1
reticulocalbin 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of RCN1 mRNA
CTD
PMID:20702594
NCBI chr11:32,091,074...32,105,722
Ensembl chr11:32,091,074...32,105,722
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RELA
RELA proto-oncogene, NF-kB subunit
multiple interactions increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to RELA promoter]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [KDM4B protein binds to RELA promoter]; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of and affects the localization of RELA protein; KDM4B protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA] Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA protein
CTD
PMID:26519613 PMID:37080397 PMID:37598416
NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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REPIN1
replication initiator 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of REPIN1 mRNA
CTD
PMID:23196670
NCBI chr 7:150,368,096...150,374,039
Ensembl chr 7:150,368,189...150,374,044
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RESP18
regulated endocrine specific protein 18
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RESP18 mRNA
CTD
PMID:20959002
NCBI chr 2:219,327,407...219,336,656
Ensembl chr 2:219,327,407...219,333,177
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RETN
resistin
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of RETN protein
CTD
PMID:28973532
NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
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RETREG1
reticulophagy regulator 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RETREG1 mRNA
CTD
PMID:23196670
NCBI chr 5:16,473,053...16,616,997
Ensembl chr 5:16,473,038...16,617,101
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RETSAT
retinol saturase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RETSAT mRNA
CTD
PMID:23196670
NCBI chr 2:85,341,955...85,354,528
Ensembl chr 2:85,341,955...85,354,531
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RFC2
replication factor C subunit 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RFC2 mRNA
CTD
PMID:23196670
NCBI chr 7:74,231,502...74,254,399
Ensembl chr 7:74,231,499...74,254,458
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RFC3
replication factor C subunit 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RFC3 mRNA
CTD
PMID:23196670
NCBI chr13:33,818,149...33,977,377
Ensembl chr13:33,818,069...33,966,558
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RGS4
regulator of G protein signaling 4
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of RGS4 mRNA
CTD
PMID:30744511
NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802
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RGS8
regulator of G protein signaling 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RGS8 mRNA
CTD
PMID:19692669
NCBI chr 1:182,641,818...182,752,376
Ensembl chr 1:182,641,816...182,684,587
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RGS9
regulator of G protein signaling 9
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RGS9 mRNA
CTD
PMID:23994337
NCBI chr17:65,137,370...65,227,703
Ensembl chr17:65,100,812...65,227,703
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RHO
rhodopsin
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHO mRNA
CTD
PMID:23146750
NCBI chr 3:129,528,639...129,535,344
Ensembl chr 3:129,528,639...129,535,344
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RHOB
ras homolog family member B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHOB mRNA
CTD
PMID:20959002
NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440
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RHOJ
ras homolog family member J
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHOJ mRNA
CTD
PMID:32119087
NCBI chr14:63,204,443...63,293,508
Ensembl chr14:63,204,114...63,293,508
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RHOU
ras homolog family member U
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHOU mRNA
CTD
PMID:32119087
NCBI chr 1:228,644,647...228,746,669
Ensembl chr 1:228,735,479...228,746,664
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RHPN1
rhophilin Rho GTPase binding protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHPN1 mRNA
CTD
PMID:32119087
NCBI chr 8:143,364,255...143,384,221
Ensembl chr 8:143,368,876...143,384,221
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RIGI
RNA sensor RIG-I
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RIGI mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RIGI mRNA
CTD
PMID:32119087 PMID:35618242
NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,348
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RNASE4
ribonuclease A family member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RNASE4 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr14:20,684,560...20,701,216
Ensembl chr14:20,684,560...20,701,216
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RNF151
ring finger protein 151
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RNF151 mRNA
CTD
PMID:23146750
NCBI chr16:1,966,856...1,968,949
Ensembl chr16:1,966,823...1,968,975
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RNF207
ring finger protein 207
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RNF207 mRNA
CTD
PMID:23146750
NCBI chr 1:6,206,119...6,221,299
Ensembl chr 1:6,205,475...6,221,299
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RNPEP
arginyl aminopeptidase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RNPEP mRNA
CTD
PMID:23196670
NCBI chr 1:201,982,648...202,006,143
Ensembl chr 1:201,982,372...202,006,147
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RPL5
ribosomal protein L5
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RPL5 mRNA
CTD
PMID:19692669
NCBI chr 1:92,831,986...92,841,924
Ensembl chr 1:92,832,013...92,841,924
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RPLP0
ribosomal protein lateral stalk subunit P0
increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RPLP0 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of RPLP0 mRNA
CTD
PMID:23994337 PMID:37080397
NCBI chr12:120,196,699...120,201,111
Ensembl chr12:120,196,699...120,201,235
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RRAD
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RRAD mRNA
CTD
PMID:29947894
NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,685...66,925,535
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RRM1
ribonucleotide reductase catalytic subunit M1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RRM1 mRNA
CTD
PMID:23196670
NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932
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RRP1B
ribosomal RNA processing 1B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RRP1B mRNA
CTD
PMID:23994337
NCBI chr21:43,659,560...43,696,079
Ensembl chr21:43,659,560...43,696,079
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RSAD2
radical S-adenosyl methionine domain containing 2
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RSAD2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RSAD2 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239
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RTN1
reticulon 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RTN1 mRNA
CTD
PMID:23196670
NCBI chr14:59,595,976...59,870,776
Ensembl chr14:59,595,976...59,870,776
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RUBCN
rubicon autophagy regulator
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RUBCN mRNA
CTD
PMID:32119087
NCBI chr 3:197,668,867...197,749,820
Ensembl chr 3:197,668,867...197,749,727
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RUFY3
RUN and FYVE domain containing 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RUFY3 mRNA
CTD
PMID:23196670
NCBI chr 4:70,703,767...70,808,619
Ensembl chr 4:70,704,204...70,808,619
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RUNX1
RUNX family transcription factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RUNX1 mRNA
CTD
PMID:23196670
NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667
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RUVBL1
RuvB like AAA ATPase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RUVBL1 mRNA
CTD
PMID:23196670
NCBI chr 3:128,064,785...128,153,914
Ensembl chr 3:128,064,778...128,153,914
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RXRA
retinoid X receptor alpha
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of RXRA mRNA
CTD
PMID:37080397
NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
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S100A1
S100 calcium binding protein A1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of S100A1 mRNA
CTD
PMID:23196670
NCBI chr 1:153,628,434...153,632,039
Ensembl chr 1:153,627,926...153,632,039
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S100A10
S100 calcium binding protein A10
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of S100A10 mRNA
CTD
PMID:19692669
NCBI chr 1:151,982,915...151,993,859
Ensembl chr 1:151,982,915...151,993,859
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SAMD9L
sterile alpha motif domain containing 9 like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SAMD9L mRNA
CTD
PMID:32119087
NCBI chr 7:93,130,056...93,148,385
Ensembl chr 7:93,130,056...93,148,385
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SAT1
spermidine/spermine N1-acetyltransferase 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SAT1 mRNA
CTD
PMID:21703328
NCBI chr X:23,783,173...23,786,210
Ensembl chr X:23,783,173...23,786,210
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SC5D
sterol-C5-desaturase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SC5D mRNA
CTD
PMID:23196670
NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410
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SCAMP5
secretory carrier membrane protein 5
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCAMP5 mRNA
CTD
PMID:23146750
NCBI chr15:74,995,563...75,021,495
Ensembl chr15:74,957,219...75,021,495
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SCARA5
scavenger receptor class A member 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SCARA5 mRNA
CTD
PMID:32119087
NCBI chr 8:27,869,883...27,992,673
Ensembl chr 8:27,869,883...27,992,673
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SCD
stearoyl-CoA desaturase
decreases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCD mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of SCD2 mRNA
CTD
PMID:20702594 PMID:23196670
NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
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SCG5
secretogranin V
affects expression increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SCG5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SCG5 mRNA
CTD
PMID:21703328 PMID:29947894
NCBI chr15:32,641,710...32,697,092
Ensembl chr15:32,641,676...32,697,098
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SCGB3A2
secretoglobin family 3A member 2
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SCGB3A2 mRNA
CTD
PMID:20702594
NCBI chr 5:147,878,711...147,882,191
Ensembl chr 5:147,870,682...147,882,191
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SCN4B
sodium voltage-gated channel beta subunit 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCN4B mRNA
CTD
PMID:23196670
NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888
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SCP2
sterol carrier protein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCP2 mRNA
CTD
PMID:23196670
NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698
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SCPEP1
serine carboxypeptidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCPEP1 mRNA
CTD
PMID:23196670
NCBI chr17:56,978,131...57,006,768
Ensembl chr17:56,978,129...57,006,768
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SCUBE3
signal peptide, CUB domain and EGF like domain containing 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCUBE3 mRNA
CTD
PMID:32119087
NCBI chr 6:35,213,956...35,253,079
Ensembl chr 6:35,213,956...35,253,079
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SDC1
syndecan 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SDC1 mRNA
CTD
PMID:20959002
NCBI chr 2:20,200,797...20,225,475
Ensembl chr 2:20,200,797...20,225,433
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SDC2
syndecan 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SDC2 mRNA
CTD
PMID:23196670
NCBI chr 8:96,493,813...96,611,790
Ensembl chr 8:96,493,813...96,611,790
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SDS
serine dehydratase
affects expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SDS mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SDS mRNA
CTD
PMID:21703328 PMID:27509375 PMID:29474705 PMID:34848246
NCBI chr12:113,392,445...113,403,887
Ensembl chr12:113,392,445...113,426,301
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SELE
selectin E
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SELE protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SELE protein]
CTD
PMID:28973532
NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
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SELENOP
selenoprotein P
decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SELENOP mRNA
CTD
PMID:19692669 PMID:23146750 PMID:23196670
NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392
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SELP
selectin P
multiple interactions increases expression decreases secretion
ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SELP protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SELP protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of SELP protein
CTD
PMID:28973532 PMID:29216392
NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193
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SEMA3G
semaphorin 3G
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SEMA3G mRNA
CTD
PMID:32119087
NCBI chr 3:52,433,035...52,445,103
Ensembl chr 3:52,433,035...52,445,103
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SEMA6A
semaphorin 6A
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SEMA6A mRNA
CTD
PMID:23146750
NCBI chr 5:116,443,555...116,574,823
Ensembl chr 5:116,443,555...116,574,823
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SEMA6B
semaphorin 6B
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SEMA6B mRNA
CTD
PMID:23146750
NCBI chr19:4,542,593...4,559,684
Ensembl chr19:4,542,593...4,581,776
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SEPTIN4
septin 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SEPTIN4 mRNA
CTD
PMID:23196670
NCBI chr17:58,520,256...58,544,328
Ensembl chr17:58,520,250...58,544,368
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SERPINA7
serpin family A member 7
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SERPINA7 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SERPINA7 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr X:106,032,435...106,038,727
Ensembl chr X:106,032,435...106,038,727
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SERPINB2
serpin family B member 2
multiple interactions increases expression
EXP
alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINB2 mRNA]
CTD
PMID:22262711 PMID:23146750 PMID:29947894
NCBI chr18:63,887,705...63,903,888
Ensembl chr18:63,871,692...63,903,888
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SERPINB9
serpin family B member 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SERPINB9 mRNA
CTD
PMID:19692669
NCBI chr 6:2,887,270...2,903,309
Ensembl chr 6:2,887,270...2,903,309
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SERPINE1
serpin family E member 1
increases expression affects expression multiple interactions increases secretion
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINE1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of SERPINE1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINE1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINE1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of SERPINE1 mRNA; [perfluorooctane sulfonic acid co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of SERPINE1 mRNA; [perfluorooctane sulfonic acid co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of SERPINE1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of SERPINE1 protein
CTD
PMID:19692669 PMID:21703328 PMID:28163111 PMID:28973532 PMID:29216392 PMID:33096110 More...
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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SERTAD2
SERTA domain containing 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERTAD2 mRNA
CTD
PMID:19692669
NCBI chr 2:64,631,621...64,653,913
Ensembl chr 2:64,631,621...64,751,005
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SF3B4
splicing factor 3b subunit 4
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SF3B4 mRNA
CTD
PMID:20702594
NCBI chr 1:149,923,317...149,927,803
Ensembl chr 1:149,923,317...149,927,803
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SFMBT1
Scm like with four mbt domains 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SFMBT1 mRNA
CTD
PMID:23196670
NCBI chr 3:52,903,572...53,046,073
Ensembl chr 3:52,903,572...53,046,750
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SFN
stratifin
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of SFN protein
CTD
PMID:23457121
NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456
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SFR1
SWI5 dependent homologous recombination repair protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SFR1 mRNA
CTD
PMID:23994337
NCBI chr10:104,120,166...104,126,383
Ensembl chr10:104,122,058...104,126,385
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SFXN1
sideroflexin 1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SFXN1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SFXN1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 5:175,478,560...175,529,742
Ensembl chr 5:175,477,062...175,529,742
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SGK2
serum/glucocorticoid regulated kinase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SGK2 mRNA
CTD
PMID:20959002
NCBI chr20:43,559,027...43,585,627
Ensembl chr20:43,558,968...43,588,237
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SH3BP5
SH3 domain binding protein 5
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SH3BP5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SH3BP5 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 3:15,254,353...15,341,380
Ensembl chr 3:15,254,353...15,341,368
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SH3RF1
SH3 domain containing ring finger 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SH3RF1 mRNA
CTD
PMID:23196670
NCBI chr 4:169,094,259...169,270,956
Ensembl chr 4:169,094,259...169,270,956
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SHC2
SHC adaptor protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SHC2 mRNA
CTD
PMID:32119087
NCBI chr19:416,589...461,033
Ensembl chr19:416,589...461,033
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SHISA8
shisa family member 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SHISA8 mRNA
CTD
PMID:32119087
NCBI chr22:41,909,543...41,915,074
Ensembl chr22:41,909,543...41,915,074
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SHMT2
serine hydroxymethyltransferase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SHMT2 mRNA
CTD
PMID:23196670
NCBI chr12:57,229,711...57,234,935
Ensembl chr12:57,229,573...57,234,935
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SHROOM2
shroom family member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SHROOM2 mRNA
CTD
PMID:23196670
NCBI chr X:9,786,429...9,949,443
Ensembl chr X:9,786,429...9,949,443
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SHROOM4
shroom family member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SHROOM4 mRNA
CTD
PMID:32119087
NCBI chr X:50,575,534...50,814,194
Ensembl chr X:50,586,796...50,814,302
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SIGMAR1
sigma non-opioid intracellular receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SIGMAR1 mRNA
CTD
PMID:23196670
NCBI chr 9:34,634,722...34,637,787
Ensembl chr 9:34,634,722...34,637,844
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SIPA1L2
signal induced proliferation associated 1 like 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SIPA1L2 mRNA
CTD
PMID:23196670
NCBI chr 1:232,397,965...232,630,496
Ensembl chr 1:232,397,965...232,630,571
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SIRPD
signal regulatory protein delta
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SIRPD mRNA
CTD
PMID:23146750
NCBI chr20:1,534,251...1,557,705
Ensembl chr20:1,534,251...1,557,705
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SIRT1
sirtuin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SIRT1 mRNA
CTD
PMID:37080397
NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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SIX5
SIX homeobox 5
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SIX5 mRNA
CTD
PMID:23146750
NCBI chr19:45,764,785...45,769,252
Ensembl chr19:45,764,785...45,769,252
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SLC13A3
solute carrier family 13 member 3
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SLC13A3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC13A3 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr20:46,557,828...46,684,485
Ensembl chr20:46,557,823...46,684,467
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SLC14A1
solute carrier family 14 member 1 (Kidd blood group)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC14A1 mRNA
CTD
PMID:23196670
NCBI chr18:45,724,181...45,752,520
Ensembl chr18:45,687,025...45,752,520
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SLC16A1
solute carrier family 16 member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC16A1 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593
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SLC16A13
solute carrier family 16 member 13
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC16A13 mRNA
CTD
PMID:23196670
NCBI chr17:7,036,015...7,040,117
Ensembl chr17:7,036,015...7,040,117
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SLC16A2
solute carrier family 16 member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC16A2 mRNA
CTD
PMID:23196670
NCBI chr X:74,421,493...74,533,916
Ensembl chr X:74,421,493...74,533,917
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SLC17A1
solute carrier family 17 member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC17A1 mRNA
CTD
PMID:19692669
NCBI chr 6:25,723,743...25,832,052
Ensembl chr 6:25,782,915...25,832,052
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SLC1A3
solute carrier family 1 member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC1A3 mRNA
CTD
PMID:23196670
NCBI chr 5:36,606,606...36,688,334
Ensembl chr 5:36,596,588...36,688,334
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SLC1A4
solute carrier family 1 member 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC1A4 mRNA
CTD
PMID:23196670
NCBI chr 2:64,988,479...65,023,865
Ensembl chr 2:64,988,477...65,023,865
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SLC1A5
solute carrier family 1 member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC1A5 mRNA
CTD
PMID:23196670
NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594
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SLC20A1
solute carrier family 20 member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC20A1 mRNA
CTD
PMID:23196670
NCBI chr 2:112,645,939...112,663,825
Ensembl chr 2:112,645,939...112,663,825
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SLC22A7
solute carrier family 22 member 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC22A7 mRNA
CTD
PMID:20959002
NCBI chr 6:43,295,714...43,305,538
Ensembl chr 6:43,295,694...43,305,538
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SLC25A10
solute carrier family 25 member 10
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC25A10 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC25A10 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr17:81,712,284...81,721,012
Ensembl chr17:81,712,236...81,721,016
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SLC25A15
solute carrier family 25 member 15
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC25A15 mRNA
CTD
PMID:32119087
NCBI chr13:40,789,611...40,812,460
Ensembl chr13:40,789,412...40,812,460
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SLC25A25
solute carrier family 25 member 25
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC25A25 mRNA
CTD
PMID:23196670
NCBI chr 9:128,068,232...128,109,245
Ensembl chr 9:128,068,201...128,109,245
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SLC25A36
solute carrier family 25 member 36
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC25A36 mRNA
CTD
PMID:32119087
NCBI chr 3:140,941,836...140,980,995
Ensembl chr 3:140,941,830...140,980,995
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SLC26A2
solute carrier family 26 member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC26A2 mRNA
CTD
PMID:23196670
NCBI chr 5:149,960,758...149,987,400
Ensembl chr 5:149,960,758...149,993,455
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SLC27A1
solute carrier family 27 member 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SLC27A1 mRNA
CTD
PMID:37080397
NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168
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SLC27A2
solute carrier family 27 member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC27A2 mRNA
CTD
PMID:23994337
NCBI chr15:50,182,196...50,236,385
Ensembl chr15:50,182,196...50,236,385
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SLC27A3
solute carrier family 27 member 3
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC27A3 mRNA
CTD
PMID:19692669
NCBI chr 1:153,775,407...153,780,157
Ensembl chr 1:153,774,354...153,780,157
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SLC27A4
solute carrier family 27 member 4
affects expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SLC27A4 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC27A4 mRNA
CTD
PMID:21703328 PMID:37080397
NCBI chr 9:128,340,527...128,361,470
Ensembl chr 9:128,340,527...128,361,470
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SLC28A2
solute carrier family 28 member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC28A2 mRNA
CTD
PMID:23196670
NCBI chr15:45,252,234...45,277,846
Ensembl chr15:45,252,234...45,277,846
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SLC29A1
solute carrier family 29 member 1 (Augustine blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC29A1 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142
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SLC2A1
solute carrier family 2 member 1
increases expression multiple interactions decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A1 mRNA
CTD
PMID:30821169 PMID:35618242 PMID:37080397
NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
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SLC2A2
solute carrier family 2 member 2
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A2 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SLC2A2 mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A2 mRNA]
CTD
PMID:26396156 PMID:28973532 PMID:29474705 PMID:34848246 PMID:37080397
NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743
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SLC2A3
solute carrier family 2 member 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A3 mRNA
CTD
PMID:23196670
NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007
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SLC2A5
solute carrier family 2 member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A5 mRNA
CTD
PMID:20959002
NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478
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SLC35C2
solute carrier family 35 member C2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of SLC35C2 mRNA
CTD
PMID:30744511
NCBI chr20:46,345,984...46,364,425
Ensembl chr20:46,345,980...46,364,458
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SLC37A4
solute carrier family 37 member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC37A4 mRNA
CTD
PMID:19692669
NCBI chr11:119,024,112...119,030,877
Ensembl chr11:119,023,751...119,030,906
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SLC38A2
solute carrier family 38 member 2
increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC38A2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of SLC38A2 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr12:46,358,188...46,372,773
Ensembl chr12:46,358,188...46,372,773
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SLC39A3
solute carrier family 39 member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC39A3 mRNA
CTD
PMID:23196670
NCBI chr19:2,732,524...2,740,076
Ensembl chr19:2,732,204...2,740,028
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SLC39A8
solute carrier family 39 member 8
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC39A8 mRNA
CTD
PMID:23146750
NCBI chr 4:102,251,041...102,345,482
Ensembl chr 4:102,251,080...102,431,258
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SLC3A2
solute carrier family 3 member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC3A2 mRNA
CTD
PMID:20959002
NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880
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SLC40A1
solute carrier family 40 member 1
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC40A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC40A1 protein
CTD
PMID:23196670 PMID:25686467
NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758
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SLC41A2
solute carrier family 41 member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC41A2 mRNA
CTD
PMID:19692669
NCBI chr12:104,801,801...104,958,746
Ensembl chr12:104,801,801...104,958,744
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SLC4A1
solute carrier family 4 member 1 (Diego blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC4A1 mRNA
CTD
PMID:20959002
NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141
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SLC5A3
solute carrier family 5 member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC5A3 mRNA
CTD
PMID:23196670
NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260
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SLC66A2
solute carrier family 66 member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC66A2 mRNA
CTD
PMID:23994337
NCBI chr18:79,902,420...79,951,653
Ensembl chr18:79,902,420...79,951,657
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SLC6A13
solute carrier family 6 member 13
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC6A13 mRNA
CTD
PMID:20959002
NCBI chr12:220,622...262,836
Ensembl chr12:220,621...262,873
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SLC6A6
solute carrier family 6 member 6
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SLC6A6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC6A6 mRNA
CTD
PMID:16984957 PMID:20959002 PMID:23196670
NCBI chr 3:14,402,576...14,489,349
Ensembl chr 3:14,402,576...14,489,349
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SLC7A1
solute carrier family 7 member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC7A1 mRNA
CTD
PMID:23196670
NCBI chr13:29,509,414...29,595,688
Ensembl chr13:29,509,414...29,595,688
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SLC7A11
solute carrier family 7 member 11
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC7A11 mRNA
CTD
PMID:19692669 PMID:23146750
NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
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SLC7A5
solute carrier family 7 member 5
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC7A5 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,023...87,869,507
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SLC7A7
solute carrier family 7 member 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC7A7 mRNA
CTD
PMID:23196670
NCBI chr14:22,773,222...22,819,791
Ensembl chr14:22,773,222...22,829,820
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SLC7A8
solute carrier family 7 member 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC7A8 mRNA
CTD
PMID:23196670
NCBI chr14:23,125,295...23,183,660
Ensembl chr14:23,125,295...23,183,674
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SLC7A9
solute carrier family 7 member 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC7A9 mRNA
CTD
PMID:23196670
NCBI chr19:32,830,511...32,869,767
Ensembl chr19:32,830,509...32,869,767
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SLC9A7
solute carrier family 9 member A7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC9A7 mRNA
CTD
PMID:32119087
NCBI chr X:46,599,251...46,759,118
Ensembl chr X:46,599,251...46,759,118
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SLCO1A2
solute carrier organic anion transporter family member 1A2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SLCO1A4 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLCO1A4 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr12:21,264,600...21,419,634
Ensembl chr12:21,264,600...21,419,594
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SLCO2A1
solute carrier organic anion transporter family member 2A1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLCO2A1 mRNA
CTD
PMID:20959002
NCBI chr 3:133,932,701...134,029,925
Ensembl chr 3:133,932,701...134,052,184
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SLCO2B1
solute carrier organic anion transporter family member 2B1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLCO2B1 mRNA
CTD
PMID:15919853
NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549
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SLCO3A1
solute carrier organic anion transporter family member 3A1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLCO3A1 mRNA
CTD
PMID:15919853
NCBI chr15:91,853,708...92,172,435
Ensembl chr15:91,853,708...92,172,435
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SLFN5
schlafen family member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLFN5 mRNA
CTD
PMID:32119087
NCBI chr17:35,243,072...35,273,655
Ensembl chr17:35,243,071...35,273,655
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SLITRK5
SLIT and NTRK like family member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLITRK5 mRNA
CTD
PMID:32119087
NCBI chr13:87,671,371...87,679,616
Ensembl chr13:87,671,371...87,696,272
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SMAD7
SMAD family member 7
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMAD7 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SMAD7 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965
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SMAD9
SMAD family member 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMAD9 mRNA
CTD
PMID:23196670
NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887
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SMARCB1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SMARCB1 mRNA
CTD
PMID:21703328
NCBI chr22:23,786,966...23,838,009
Ensembl chr22:23,786,931...23,838,009
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SMIM3
small integral membrane protein 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMIM3 mRNA
CTD
PMID:23196670
NCBI chr 5:150,778,757...150,796,734
Ensembl chr 5:150,778,757...150,796,734
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SMPD1
sphingomyelin phosphodiesterase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMPD1 mRNA
CTD
PMID:32119087
NCBI chr11:6,390,474...6,394,996
Ensembl chr11:6,390,440...6,394,998
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SMPD3
sphingomyelin phosphodiesterase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMPD3 mRNA
CTD
PMID:23196670
NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508
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SNAI1
snail family transcriptional repressor 1
decreases expression increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SNAI1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]
CTD
PMID:23196670 PMID:28284859
NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886
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SNAP23
synaptosome associated protein 23
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAP23 mRNA
CTD
PMID:32119087
NCBI chr15:42,491,129...42,533,058
Ensembl chr15:42,491,233...42,545,356
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SNCG
synuclein gamma
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SNCG mRNA
CTD
PMID:32119087
NCBI chr10:86,955,759...86,963,258
Ensembl chr10:86,958,599...86,963,258
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SNRK
SNF related kinase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SNRK mRNA
CTD
PMID:23994337
NCBI chr 3:43,286,540...43,351,143
Ensembl chr 3:43,286,512...43,424,764
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SNX24
sorting nexin 24
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SNX24 mRNA
CTD
PMID:23196670
NCBI chr 5:122,845,613...123,029,318
Ensembl chr 5:122,843,439...123,029,354
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SOCS2
suppressor of cytokine signaling 2
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOCS2 mRNA
CTD
PMID:15371557 PMID:19692669
NCBI chr12:93,569,969...93,626,236
Ensembl chr12:93,569,814...93,583,487
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SOD1
superoxide dismutase 1
increases activity decreases expression multiple interactions decreases activity increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased activity of SOD1 protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SOD1 mRNA Sunphenon inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SOD1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of SOD1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOD1 mRNA
CTD
PMID:24378064 PMID:25433332 PMID:26967026 PMID:37080397
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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SOD2
superoxide dismutase 2
increases expression decreases activity
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOD2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOD2 protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of SOD2 protein
CTD
PMID:26660635 PMID:26967026
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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SOD3
superoxide dismutase 3
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SOD3 mRNA
CTD
PMID:37080397
NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
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SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOS1 mRNA
CTD
PMID:19692669
NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345
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SP140
SP140 nuclear body protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SP140 mRNA
CTD
PMID:23196670
NCBI chr 2:230,186,151...230,316,571
Ensembl chr 2:230,203,110...230,313,215
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SPARC
secreted protein acidic and cysteine rich
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SPARC mRNA
CTD
PMID:20959002
NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
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SPARCL1
SPARC like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SPARCL1 mRNA
CTD
PMID:20959002
NCBI chr 4:87,473,335...87,529,376
Ensembl chr 4:87,473,335...87,531,061
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SPC25
SPC25 component of NDC80 kinetochore complex
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SPC25 mRNA
CTD
PMID:23196670
NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371
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SPINK8
serine peptidase inhibitor Kazal type 8 (putative)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPINK8 mRNA
CTD
PMID:32119087
NCBI chr 3:48,306,842...48,333,661
Ensembl chr 3:48,306,842...48,333,661
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SPON1
spondin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPON1 mRNA
CTD
PMID:23196670
NCBI chr11:13,962,723...14,268,133
Ensembl chr11:13,962,723...14,268,133
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SPP1
secreted phosphoprotein 1
affects expression increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SPP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SPP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPP1 mRNA
CTD
PMID:20959002 PMID:21703328 PMID:23146750 PMID:37080397
NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
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SPP2
secreted phosphoprotein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPP2 mRNA
CTD
PMID:19692669
NCBI chr 2:234,050,702...234,077,134
Ensembl chr 2:234,050,679...234,077,134
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SPTBN1
spectrin beta, non-erythrocytic 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPTBN1 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 2:54,456,327...54,671,446
Ensembl chr 2:54,456,327...54,671,446
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SQLE
squalene epoxidase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SQLE mRNA
CTD
PMID:23196670
NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283
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SRD5A1
steroid 5 alpha-reductase 1
multiple interactions decreases expression increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] affects the expression of SRD5A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SRD5A1 mRNA; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRD5A1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SRD5A1 mRNA
CTD
PMID:16984957 PMID:19464308 PMID:20959002 PMID:34256052
NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539
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SRD5A2
steroid 5 alpha-reductase 2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] affects the expression of SRD5A2 protein
CTD
PMID:19464308
NCBI chr 2:31,522,480...31,663,009
Ensembl chr 2:31,522,480...31,580,938
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SREBF1
sterol regulatory element binding transcription factor 1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SREBF1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SREBF1 protein
CTD
PMID:23994337 PMID:26693162
NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
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SRGN
serglycin
affects expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SRGN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SRGN mRNA
CTD
PMID:20702594 PMID:23196670
NCBI chr10:69,087,603...69,104,811
Ensembl chr10:69,088,103...69,104,805
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SRM
spermidine synthase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRM mRNA
CTD
PMID:23196670
NCBI chr 1:11,054,589...11,060,018
Ensembl chr 1:11,054,584...11,060,020
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SRP19
signal recognition particle 19
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRP19 mRNA
CTD
PMID:23994337
NCBI chr 5:112,861,287...112,898,371
Ensembl chr 5:112,861,188...112,898,371
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SRPRA
SRP receptor subunit alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRPRA mRNA
CTD
PMID:23994337
NCBI chr11:126,235,930...126,268,895
Ensembl chr11:126,262,938...126,269,144
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SRPX
sushi repeat containing protein X-linked
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SRPX mRNA
CTD
PMID:23196670
NCBI chr X:38,149,339...38,220,871
Ensembl chr X:38,149,336...38,220,924
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SST
somatostatin
multiple interactions
ISO
[2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of SST mRNA
CTD
PMID:19327374
NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394
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SSUH2
ssu-2 homolog
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SSUH2 mRNA
CTD
PMID:32119087
NCBI chr 3:8,619,386...8,681,927
Ensembl chr 3:8,619,386...8,745,040
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ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ST3GAL1 mRNA
CTD
PMID:23196670
NCBI chr 8:133,454,848...133,571,887
Ensembl chr 8:133,454,848...133,571,926
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ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ST6GAL1 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 3:186,930,526...187,078,553
Ensembl chr 3:186,930,325...187,078,553
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ST6GALNAC3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ST6GALNAC3 mRNA
CTD
PMID:23196670
NCBI chr 1:76,074,746...76,637,339
Ensembl chr 1:76,074,746...76,634,603
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STAB1
stabilin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAB1 mRNA
CTD
PMID:32119087
NCBI chr 3:52,495,338...52,524,495
Ensembl chr 3:52,495,338...52,524,495
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STAR
steroidogenic acute regulatory protein
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAR mRNA
CTD
PMID:20574914
NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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STAT1
signal transducer and activator of transcription 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT1 mRNA
CTD
PMID:22262711
NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
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STAT3
signal transducer and activator of transcription 3
multiple interactions increases expression
EXP
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form
CTD
PMID:28284859
NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
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STC1
stanniocalcin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of STC1 mRNA
CTD
PMID:23196670
NCBI chr 8:23,841,929...23,854,806
Ensembl chr 8:23,841,929...23,854,806
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STC2
stanniocalcin 2
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STC2 mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr 5:173,314,723...173,328,414
Ensembl chr 5:173,314,723...173,328,447
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STON1
stonin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of STON1 mRNA
CTD
PMID:23196670
NCBI chr 2:48,530,154...48,598,513
Ensembl chr 2:48,529,383...48,598,513
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STOX2
storkhead box 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of STOX2 mRNA
CTD
PMID:23196670
NCBI chr 4:183,798,022...184,023,530
Ensembl chr 4:183,797,692...184,023,526
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STXBP3
syntaxin binding protein 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of STXBP3 mRNA
CTD
PMID:23196670
NCBI chr 1:108,746,674...108,809,523
Ensembl chr 1:108,746,674...108,809,523
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SUGCT
succinyl-CoA:glutarate-CoA transferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SUGCT mRNA
CTD
PMID:23196670
NCBI chr 7:40,135,005...41,038,816
Ensembl chr 7:40,135,005...40,860,763
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SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SUGT1 mRNA
CTD
PMID:32119087
NCBI chr13:52,652,836...52,700,909
Ensembl chr13:52,652,709...52,700,909
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SULF1
sulfatase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SULF1 mRNA
CTD
PMID:23196670
NCBI chr 8:69,466,781...69,660,912
Ensembl chr 8:69,466,624...69,660,915
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SULT1A1
sulfotransferase family 1A member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SULT1A1 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044
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SULT1B1
sulfotransferase family 1B member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SULT1B1 mRNA
CTD
PMID:19692669
NCBI chr 4:69,721,167...69,760,620
Ensembl chr 4:69,721,167...69,787,961
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SULT1C3
sulfotransferase family 1C member 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SULT1C1 mRNA
CTD
PMID:20959002
NCBI chr 2:108,239,968...108,265,351
Ensembl chr 2:108,239,968...108,265,351
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SULT1E1
sulfotransferase family 1E member 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SULT1E1 mRNA
CTD
PMID:25433332
NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145
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SUSD4
sushi domain containing 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SUSD4 mRNA
CTD
PMID:32119087
NCBI chr 1:223,220,831...223,365,235
Ensembl chr 1:223,220,819...223,364,233
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SYCN
syncollin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SYCN mRNA
CTD
PMID:20959002
NCBI chr19:39,202,825...39,204,263
Ensembl chr19:39,202,825...39,204,263
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SYMPK
symplekin scaffold protein
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SYMPK mRNA
CTD
PMID:23146750
NCBI chr19:45,815,410...45,863,147
Ensembl chr19:45,815,410...45,863,225
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SYNJ2
synaptojanin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SYNJ2 mRNA
CTD
PMID:20959002
NCBI chr 6:157,981,296...158,099,176
Ensembl chr 6:157,981,863...158,099,176
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SYNPO
synaptopodin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SYNPO mRNA
CTD
PMID:23196670
NCBI chr 5:150,586,010...150,659,207
Ensembl chr 5:150,601,080...150,659,207
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SYT12
synaptotagmin 12
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SYT12 mRNA
CTD
PMID:23196670
NCBI chr11:67,006,771...67,050,863
Ensembl chr11:67,006,778...67,050,863
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SYT15
synaptotagmin 15
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SYT15 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SYT15 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr10:46,579,128...46,597,108
Ensembl chr10:46,578,217...46,594,173
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SYTL5
synaptotagmin like 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SYTL5 mRNA
CTD
PMID:32119087
NCBI chr X:37,888,915...38,128,820
Ensembl chr X:38,006,553...38,128,819
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TACC1
transforming acidic coiled-coil containing protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TACC1 mRNA
CTD
PMID:23196670
NCBI chr 8:38,728,582...38,853,028
Ensembl chr 8:38,728,186...38,853,028
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TACC3
transforming acidic coiled-coil containing protein 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TACC3 mRNA
CTD
PMID:23196670
NCBI chr 4:1,721,521...1,745,171
Ensembl chr 4:1,712,858...1,745,171
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TACR1
tachykinin receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TACR1 mRNA
CTD
PMID:32119087
NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520
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TAGLN
transgelin
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TAGLN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAGLN mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464
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TAMALIN
trafficking regulator and scaffold protein tamalin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TAMALIN mRNA
CTD
PMID:32119087
NCBI chr12:52,006,946...52,015,889
Ensembl chr12:52,006,946...52,015,889
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TAP1
transporter 1, ATP binding cassette subfamily B member
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAP1 mRNA
CTD
PMID:23196670
NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816
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TAPBP
TAP binding protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAPBP mRNA
CTD
PMID:23196670
NCBI chr 6:33,299,694...33,314,078
Ensembl chr 6:33,299,694...33,314,284
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TAT
tyrosine aminotransferase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAT mRNA
CTD
PMID:19692669
NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
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TAX1BP1
Tax1 binding protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAX1BP1 mRNA
CTD
PMID:23196670
NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564
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TBC1D1
TBC1 domain family member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TBC1D1 mRNA
CTD
PMID:32119087
NCBI chr 4:37,891,084...38,139,173
Ensembl chr 4:37,891,084...38,139,175
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TBCEL
tubulin folding cofactor E like
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TBCEL mRNA
CTD
PMID:23994337
NCBI chr11:121,024,102...121,090,776
Ensembl chr11:121,024,072...121,090,776
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TBX3
T-box transcription factor 3
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TBX3 mRNA
CTD
PMID:19692669
NCBI chr12:114,670,255...114,684,175
Ensembl chr12:114,670,255...114,684,175
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TC2N
tandem C2 domains, nuclear
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TC2N mRNA
CTD
PMID:32119087
NCBI chr14:91,779,746...91,867,536
Ensembl chr14:91,779,746...91,867,536
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TCF7L2
transcription factor 7 like 2
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TCF7L2 mRNA
CTD
PMID:37080397
NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678
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TCN2
transcobalamin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TCN2 mRNA
CTD
PMID:23196670
NCBI chr22:30,607,174...30,627,271
Ensembl chr22:30,607,003...30,627,271
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TCP11L2
t-complex 11 like 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TCP11L2 mRNA
CTD
PMID:23196670
NCBI chr12:106,297,935...106,347,003
Ensembl chr12:106,301,929...106,347,003
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TDO2
tryptophan 2,3-dioxygenase
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TDO2 mRNA
CTD
PMID:35618242
NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
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TEF
TEF transcription factor, PAR bZIP family member
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TEF mRNA
CTD
PMID:23196670
NCBI chr22:41,367,455...41,399,326
Ensembl chr22:41,367,333...41,399,326
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TENM3
teneurin transmembrane protein 3
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TENM3 mRNA
CTD
PMID:23146750
NCBI chr 4:181,447,613...182,803,024
Ensembl chr 4:182,143,987...182,803,024
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TENT5C
terminal nucleotidyltransferase 5C
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TENT5C mRNA
CTD
PMID:23196670
NCBI chr 1:117,606,048...117,628,389
Ensembl chr 1:117,606,048...117,628,389
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TERC
telomerase RNA component
multiple interactions decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TERC mRNA
CTD
PMID:26330309
NCBI chr 3:169,764,610...169,765,060
Ensembl chr 3:169,764,610...169,765,047 Ensembl chr 3:169,764,610...169,765,047
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TERF1
telomeric repeat binding factor 1
decreases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TERF1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TERF1 mRNA
CTD
PMID:26330309
NCBI chr 8:73,008,864...73,048,123
Ensembl chr 8:73,008,856...73,048,123
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TERF2
telomeric repeat binding factor 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TERF2 mRNA
CTD
PMID:26330309
NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571
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TERT
telomerase reverse transcriptase
multiple interactions decreases activity decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of TERT protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of TERT protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TERT mRNA
CTD
PMID:26330309
NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
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TEX2
testis expressed 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TEX2 mRNA
CTD
PMID:32119087
NCBI chr17:64,147,227...64,263,260
Ensembl chr17:64,147,227...64,263,260
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TFPI2
tissue factor pathway inhibitor 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TFPI2 mRNA
CTD
PMID:29947894
NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753
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TGFB2
transforming growth factor beta 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TGFB2 mRNA
CTD
PMID:23196670
NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
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TGFB3
transforming growth factor beta 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TGFB3 mRNA
CTD
PMID:23196670
NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011
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TGFBI
transforming growth factor beta induced
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TGFBI mRNA
CTD
PMID:22262711
NCBI chr 5:136,028,988...136,063,818
Ensembl chr 5:136,028,988...136,063,818
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TGM2
transglutaminase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TGM2 mRNA
CTD
PMID:23196670
NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578
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THBD
thrombomodulin
affects expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of THBD mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of THBD protein [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of THBD protein
CTD
PMID:20702594 PMID:28973532
NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
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THOP1
thimet oligopeptidase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of THOP1 mRNA
CTD
PMID:32119087
NCBI chr19:2,785,503...2,815,807
Ensembl chr19:2,785,503...2,815,807
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THRB
thyroid hormone receptor beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of THRB mRNA
CTD
PMID:20959002
NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756
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THY1
Thy-1 cell surface antigen
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of THY1 mRNA
CTD
PMID:23196670
NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985
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TIMP1
TIMP metallopeptidase inhibitor 1
increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TIMP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA
CTD
PMID:28163111 PMID:28973532 PMID:35618242
NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789
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TIMP3
TIMP metallopeptidase inhibitor 3
decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TIMP3 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041
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TIPARP
TCDD inducible poly(ADP-ribose) polymerase
affects expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TIPARP mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TIPARP mRNA
CTD
PMID:18042819 PMID:19692669 PMID:20702594 PMID:23146750 PMID:23994337 PMID:29738842 PMID:29947894 PMID:32119087 More...
NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770
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TJP1
tight junction protein 1
decreases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein acetovanillone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein] 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [TJP1 protein binds to OCLN protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein
CTD
PMID:20064788 PMID:20299304 PMID:37598416
NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
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TKFC
triokinase and FMN cyclase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TKFC mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr11:61,333,228...61,353,426
Ensembl chr11:61,333,220...61,353,295
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TLR4
toll like receptor 4
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TLR4 mRNA
CTD
PMID:21703328
NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
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TLR6
toll like receptor 6
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TLR6 mRNA
CTD
PMID:23146750
NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817
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TM7SF2
transmembrane 7 superfamily member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TM7SF2 mRNA
CTD
PMID:23196670
NCBI chr11:65,111,872...65,116,230
Ensembl chr11:65,111,845...65,116,384
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TMEM100
transmembrane protein 100
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM100 mRNA
CTD
PMID:23196670
NCBI chr17:55,719,627...55,732,081
Ensembl chr17:55,719,627...55,732,121
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TMEM138
transmembrane protein 138
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM138 mRNA
CTD
PMID:23196670
NCBI chr11:61,362,374...61,376,870
Ensembl chr11:61,361,964...61,377,890
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TMEM150C
transmembrane protein 150C
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of TMEM150C mRNA
CTD
PMID:30744511
NCBI chr 4:82,483,176...82,562,253
Ensembl chr 4:82,483,170...82,562,357
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TMEM176B
transmembrane protein 176B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM176B mRNA
CTD
PMID:23196670
NCBI chr 7:150,791,301...150,801,360
Ensembl chr 7:150,791,285...150,801,360
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TMEM200A
transmembrane protein 200A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM200A mRNA
CTD
PMID:32119087
NCBI chr 6:130,365,531...130,443,067
Ensembl chr 6:130,366,017...130,443,067
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TMEM204
transmembrane protein 204
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM204 mRNA
CTD
PMID:23196670
NCBI chr16:1,528,678...1,555,568
Ensembl chr16:1,528,688...1,555,580
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TMEM236
transmembrane protein 236
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM236 mRNA
CTD
PMID:32119087
NCBI chr10:17,752,201...17,800,868
Ensembl chr10:17,752,201...17,800,868
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TMEM254
transmembrane protein 254
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM254 mRNA
CTD
PMID:23196670
NCBI chr10:80,078,665...80,092,551
Ensembl chr10:80,078,646...80,092,557
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TMEM37
transmembrane protein 37
decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM37 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM37 mRNA
CTD
PMID:23146750 PMID:32119087
NCBI chr 2:119,429,895...119,438,504
Ensembl chr 2:119,429,901...119,438,504
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TMEM47
transmembrane protein 47
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM47 mRNA
CTD
PMID:19692669
NCBI chr X:34,627,075...34,657,285
Ensembl chr X:34,627,075...34,657,285
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TMEM97
transmembrane protein 97
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM97 mRNA
CTD
PMID:23196670
NCBI chr17:28,319,200...28,328,685
Ensembl chr17:28,319,200...28,328,685
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TMOD1
tropomodulin 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMOD1 mRNA
CTD
PMID:19692669
NCBI chr 9:97,501,180...97,601,743
Ensembl chr 9:97,501,180...97,601,743
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TNF
tumor necrosis factor
multiple interactions decreases expression increases expression increases secretion decreases secretion
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with TNF protein] results in increased expression of CCNA2 mRNA; TNF protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TNF mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of TNF mRNA; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF protein 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of TNF protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of TNF protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of TNF protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of TNF protein
CTD
PMID:17557910 PMID:25433332 PMID:28163111 PMID:28973532 PMID:30768972 PMID:31563530 PMID:35618242 PMID:37598416 More...
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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TNFAIP2
TNF alpha induced protein 2
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFAIP2 mRNA
CTD
PMID:19692669 PMID:23994337
NCBI chr14:103,121,469...103,137,439
Ensembl chr14:103,121,476...103,137,439
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TNFAIP3
TNF alpha induced protein 3
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFAIP3 mRNA
CTD
PMID:35618242
NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
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TNFAIP6
TNF alpha induced protein 6
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFAIP6 mRNA
CTD
PMID:35618242
NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046
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TNFAIP8L3
TNF alpha induced protein 8 like 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFAIP8L3 mRNA
CTD
PMID:32119087
NCBI chr15:51,056,601...51,105,276
Ensembl chr15:51,056,598...51,105,276
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TNFRSF11B
TNF receptor superfamily member 11b
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFRSF11B mRNA
CTD
PMID:22262711 PMID:28351761 PMID:34256052
NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
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TNFRSF13B
TNF receptor superfamily member 13B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TNFRSF13B mRNA
CTD
PMID:32119087
NCBI chr17:16,939,081...16,972,118
Ensembl chr17:16,929,816...16,972,118
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TNFRSF21
TNF receptor superfamily member 21
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFRSF21 mRNA
CTD
PMID:20959002
NCBI chr 6:47,231,532...47,309,905
Ensembl chr 6:47,231,532...47,309,905
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TNFRSF9
TNF receptor superfamily member 9
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFRSF9 mRNA
CTD
PMID:35618242
NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165
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TNFSF10
TNF superfamily member 10
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFSF10 mRNA
CTD
PMID:34256052
NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
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TNFSF13
TNF superfamily member 13
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TNFSF13 mRNA
CTD
PMID:23196670
NCBI chr17:7,558,282...7,561,601
Ensembl chr17:7,558,292...7,561,608
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TNFSF14
TNF superfamily member 14
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TNFSF14 mRNA
CTD
PMID:21703328
NCBI chr19:6,661,253...6,670,588
Ensembl chr19:6,661,253...6,670,588
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TNNT3
troponin T3, fast skeletal type
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNNT3 mRNA
CTD
PMID:32119087
NCBI chr11:1,919,552...1,938,702
Ensembl chr11:1,919,703...1,938,706
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TP53
tumor protein p53
decreases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TP53 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TP53 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene affects the localization of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [leptomycin B results in increased expression of TP53 protein]
CTD
PMID:19751709 PMID:20840854 PMID:21703328
NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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TP53INP1
tumor protein p53 inducible nuclear protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRP53INP1 mRNA
CTD
PMID:23196670
NCBI chr 8:94,925,972...94,949,378
Ensembl chr 8:94,925,972...94,949,378
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TPM1
tropomyosin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TPM1 mRNA
CTD
PMID:19692669
NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915
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TPRA1
transmembrane protein adipocyte associated 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TPRA1 mRNA
CTD
PMID:19692669
NCBI chr 3:127,571,232...127,598,231
Ensembl chr 3:127,571,232...127,598,267
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TPRN
taperin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TPRN mRNA
CTD
PMID:23196670
NCBI chr 9:137,191,619...137,200,741
Ensembl chr 9:137,191,617...137,204,193
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TPT1
tumor protein, translationally-controlled 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of TPT1 mRNA
CTD
PMID:30744511
NCBI chr13:45,333,471...45,341,183
Ensembl chr13:45,333,471...45,341,284
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TRAM2
translocation associated membrane protein 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRAM2 mRNA
CTD
PMID:23146750
NCBI chr 6:52,497,408...52,577,060
Ensembl chr 6:52,497,408...52,577,060
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TRIB2
tribbles pseudokinase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRIB2 mRNA
CTD
PMID:32119087
NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734
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TRIB3
tribbles pseudokinase 3
decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRIB3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRIB3 mRNA
CTD
PMID:20959002 PMID:22262711
NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
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TRIL
TLR4 interactor with leucine rich repeats
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRIL mRNA
CTD
PMID:32119087
NCBI chr 7:28,953,358...28,958,330
Ensembl chr 7:28,953,358...28,958,330
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TRIM15
tripartite motif containing 15
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRIM15 mRNA
CTD
PMID:29947894
NCBI chr 6:30,163,546...30,172,693
Ensembl chr 6:30,163,206...30,172,693
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TRIM47
tripartite motif containing 47
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRIM47 mRNA
CTD
PMID:32119087
NCBI chr17:75,874,164...75,878,581
Ensembl chr17:75,874,164...75,878,581
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TRIM63
tripartite motif containing 63
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRIM63 mRNA
CTD
PMID:23196670
NCBI chr 1:26,051,301...26,067,630
Ensembl chr 1:26,051,301...26,068,436
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TRIP13
thyroid hormone receptor interactor 13
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRIP13 mRNA
CTD
PMID:23196670
NCBI chr 5:892,884...919,348
Ensembl chr 5:892,884...919,357
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TRPC4
transient receptor potential cation channel subfamily C member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRPC4 mRNA
CTD
PMID:32119087
NCBI chr13:37,632,063...37,869,772
Ensembl chr13:37,632,063...37,869,802
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TRPM5
transient receptor potential cation channel subfamily M member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRPM5 mRNA
CTD
PMID:32119087
NCBI chr11:2,403,991...2,444,514
Ensembl chr11:2,404,515...2,444,514
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TRPV1
transient receptor potential cation channel subfamily V member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRPV1 mRNA
CTD
PMID:32119087
NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
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TRPV5
transient receptor potential cation channel subfamily V member 5
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in increased expression of TRPV5 mRNA
CTD
PMID:31820026
NCBI chr 7:142,908,101...142,933,746
Ensembl chr 7:142,908,101...142,933,746
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TRPV6
transient receptor potential cation channel subfamily V member 6
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in decreased expression of TRPV6 mRNA
CTD
PMID:31820026
NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745
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TSC22D1
TSC22 domain family member 1
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TSC22D1 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of TSC22D1 mRNA
CTD
PMID:16984957 PMID:19692669 PMID:20959002
NCBI chr13:44,432,143...44,577,344
Ensembl chr13:44,432,143...44,577,147
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TSHB
thyroid stimulating hormone subunit beta
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSHB protein
CTD
PMID:17379623
NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302
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TSKU
tsukushi, small leucine rich proteoglycan
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TSKU mRNA
CTD
PMID:20702594
NCBI chr11:76,782,280...76,798,144
Ensembl chr11:76,782,251...76,798,153
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TSNAX
translin associated factor X
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSNAX mRNA
CTD
PMID:19692669
NCBI chr 1:231,528,669...231,566,524
Ensembl chr 1:231,528,541...231,566,524
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TSPAN5
tetraspanin 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TSPAN5 mRNA
CTD
PMID:23196670
NCBI chr 4:98,470,367...98,658,611
Ensembl chr 4:98,470,367...98,658,611
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TSPAN7
tetraspanin 7
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSPAN7 mRNA
CTD
PMID:23994337
NCBI chr X:38,561,542...38,688,918
Ensembl chr X:38,561,542...38,688,920
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TSPAN8
tetraspanin 8
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TSPAN8 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSPAN8 mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr12:71,125,096...71,157,999
Ensembl chr12:71,125,085...71,441,898
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TSPO
translocator protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSPO mRNA
CTD
PMID:20959002
NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242
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TSPYL4
TSPY like 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TSPYL4 mRNA
CTD
PMID:23196670
NCBI chr 6:116,249,964...116,254,075
Ensembl chr 6:116,249,964...116,254,075
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TST
thiosulfate sulfurtransferase
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TST mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TST mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr22:37,010,859...37,020,183
Ensembl chr22:37,010,859...37,020,183
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TTC4
tetratricopeptide repeat domain 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TTC4 mRNA
CTD
PMID:23196670
NCBI chr 1:54,715,861...54,742,657
Ensembl chr 1:54,715,861...54,742,657
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TTL
tubulin tyrosine ligase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TTL mRNA
CTD
PMID:23196670
NCBI chr 2:112,482,156...112,541,739
Ensembl chr 2:112,482,156...112,541,739
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TUB
TUB bipartite transcription factor
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TUB mRNA
CTD
PMID:23146750
NCBI chr11:8,019,059...8,106,243
Ensembl chr11:8,019,244...8,106,243
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TUBA4A
tubulin alpha 4a
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TUBA4A mRNA
CTD
PMID:20959002
NCBI chr 2:219,249,710...219,254,740
Ensembl chr 2:219,249,710...219,277,902
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TUBB
tubulin beta class I
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TUBB5 mRNA
CTD
PMID:37080397
NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538
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TUBB2B
tubulin beta 2B class IIb
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TUBB2B mRNA
CTD
PMID:32119087
NCBI chr 6:3,224,277...3,227,653
Ensembl chr 6:3,223,324...3,231,730
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TXN2
thioredoxin 2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] results in increased expression of TXN2 mRNA
CTD
PMID:24378064
NCBI chr22:36,467,046...36,481,640
Ensembl chr22:36,467,046...36,481,640
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TXNIP
thioredoxin interacting protein
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TXNIP mRNA
CTD
PMID:19692669
NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
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TXNL4A
thioredoxin like 4A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TXNL4A mRNA
CTD
PMID:23994337
NCBI chr18:79,970,813...80,033,936
Ensembl chr18:79,970,813...80,033,949
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TXNRD1
thioredoxin reductase 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of TXNRD1 mRNA
CTD
PMID:24378064
NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
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TXNRD2
thioredoxin reductase 2
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TXNRD2 mRNA
CTD
PMID:37080397
NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820
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TYRO3
TYRO3 protein tyrosine kinase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TYRO3 mRNA
CTD
PMID:23196670
NCBI chr15:41,559,212...41,583,589
Ensembl chr15:41,557,675...41,583,589
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UBE2Q2
ubiquitin conjugating enzyme E2 Q2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UBE2Q2 mRNA
CTD
PMID:23146750
NCBI chr15:75,843,447...75,901,078
Ensembl chr15:75,843,307...75,901,078
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UCHL5
ubiquitin C-terminal hydrolase L5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UCHL5 mRNA
CTD
PMID:23196670
NCBI chr 1:193,012,254...193,060,076
Ensembl chr 1:193,012,250...193,060,080
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UGCG
UDP-glucose ceramide glucosyltransferase
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGCG mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UGCG mRNA
CTD
PMID:19692669 PMID:23196670 PMID:29947894
NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369
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UGDH
UDP-glucose 6-dehydrogenase
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of UGDH protein
CTD
PMID:23457121
NCBI chr 4:39,498,755...39,527,439
Ensembl chr 4:39,498,755...39,528,311
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UGT1A1
UDP glucuronosyltransferase family 1 member A1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGT1A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UGT1A1 mRNA
CTD
PMID:19144771 PMID:19692669 PMID:20959002 PMID:26770886
NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
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UGT1A3
UDP glucuronosyltransferase family 1 member A3
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGT1A3 mRNA
CTD
PMID:29947894
NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300
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UGT1A6
UDP glucuronosyltransferase family 1 member A6
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGT1A6 mRNA
CTD
PMID:19144771 PMID:19692669 PMID:20959002
NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300
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UGT1A9
UDP glucuronosyltransferase family 1 member A9
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGT1A9 mRNA
CTD
PMID:19144771
NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
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UHRF1
ubiquitin like with PHD and ring finger domains 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UHRF1 mRNA
CTD
PMID:23196670
NCBI chr19:4,903,080...4,962,154
Ensembl chr19:4,903,080...4,962,154
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UNG
uracil DNA glycosylase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UNG mRNA
CTD
PMID:20959002
NCBI chr12:109,097,597...109,110,992
Ensembl chr12:109,097,597...109,126,725
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UPB1
beta-ureidopropionase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UPB1 mRNA
CTD
PMID:19692669
NCBI chr22:24,495,332...24,528,390
Ensembl chr22:24,494,107...24,528,390
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USP18
ubiquitin specific peptidase 18
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of USP18 mRNA
CTD
PMID:32119087
NCBI chr22:18,150,170...18,177,397
Ensembl chr22:18,149,843...18,177,397
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USP22
ubiquitin specific peptidase 22
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of USP22 mRNA
CTD
PMID:32119087
NCBI chr17:20,999,596...21,043,419
Ensembl chr17:20,999,596...21,043,760
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UTP25
UTP25 small subunit processome component
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UTP25 mRNA
CTD
PMID:23994337
NCBI chr 1:209,827,972...209,857,565
Ensembl chr 1:209,827,972...209,857,565
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UTRN
utrophin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UTRN mRNA
CTD
PMID:23196670
NCBI chr 6:144,285,335...144,853,034
Ensembl chr 6:144,285,335...144,853,034
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UVRAG
UV radiation resistance associated
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UVRAG mRNA
CTD
PMID:23994337
NCBI chr11:75,815,210...76,144,232
Ensembl chr11:75,815,210...76,144,232
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VCAM1
vascular cell adhesion molecule 1
multiple interactions decreases expression increases expression affects expression
ISO EXP
CAV1 gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of VCAM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein 3,4,5,3',4'-pentachlorobiphenyl affects the expression of VCAM1 mRNA
CTD
PMID:20406653 PMID:22262711 PMID:23196670 PMID:24709675 PMID:26519613 PMID:37080397 More...
NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
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VCAN
versican
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAN mRNA
CTD
PMID:35618242
NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303
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VEGFA
vascular endothelial growth factor A
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VEGFA mRNA
CTD
PMID:28351761
NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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VEGFC
vascular endothelial growth factor C
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VEGFC mRNA
CTD
PMID:23196670
NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922
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VEGFD
vascular endothelial growth factor D
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of VEGFD mRNA
CTD
PMID:23196670
NCBI chr X:15,345,596...15,384,413
Ensembl chr X:15,345,596...15,384,413
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VIL1
villin 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIL1 mRNA
CTD
PMID:23146750
NCBI chr 2:218,419,123...218,453,295
Ensembl chr 2:218,419,121...218,453,295
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VIM
vimentin
increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]
CTD
PMID:23196670 PMID:28284859
NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
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VRK1
VRK serine/threonine kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VRK1 mRNA
CTD
PMID:23196670
NCBI chr14:96,797,382...96,881,609
Ensembl chr14:96,797,304...96,954,846
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VRK3
VRK serine/threonine kinase 3
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VRK3 mRNA
CTD
PMID:19692669
NCBI chr19:49,976,468...50,025,372
Ensembl chr19:49,976,468...50,025,946
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VWA5A
von Willebrand factor A domain containing 5A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of VWA5A mRNA
CTD
PMID:23196670
NCBI chr11:124,115,450...124,147,721
Ensembl chr11:124,115,404...124,147,721
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WDR45
WD repeat domain 45
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of WDR45 mRNA
CTD
PMID:23994337
NCBI chr X:49,074,442...49,101,178
Ensembl chr X:49,074,433...49,101,170
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WDR76
WD repeat domain 76
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WDR76 mRNA
CTD
PMID:23146750
NCBI chr15:43,827,002...43,868,412
Ensembl chr15:43,826,980...43,868,412
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WDR86
WD repeat domain 86
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of WDR86 mRNA
CTD
PMID:32119087
NCBI chr 7:151,368,955...151,410,712
Ensembl chr 7:151,375,909...151,410,727
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WNK4
WNK lysine deficient protein kinase 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WNK4 mRNA
CTD
PMID:23196670
NCBI chr17:42,780,610...42,797,066
Ensembl chr17:42,780,610...42,797,066
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WNT5A
Wnt family member 5A
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WNT5A mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of WNT5A mRNA
CTD
PMID:22262711 PMID:23196670 PMID:35618242
NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539
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WNT7B
Wnt family member 7B
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WNT7B mRNA
CTD
PMID:29947894
NCBI chr22:45,920,366...45,977,162
Ensembl chr22:45,920,366...45,977,162
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WRNIP1
WRN helicase interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WRNIP1 mRNA
CTD
PMID:23196670
NCBI chr 6:2,765,393...2,786,952
Ensembl chr 6:2,765,393...2,786,952
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XAF1
XIAP associated factor 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of XAF1 mRNA
CTD
PMID:23146750
NCBI chr17:6,755,447...6,775,647
Ensembl chr17:6,755,447...6,775,647
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XBP1
X-box binding protein 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of XBP1 mRNA
CTD
PMID:37080397
NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
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XCR1
X-C motif chemokine receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XCR1 mRNA
CTD
PMID:32119087
NCBI chr 3:46,017,007...46,085,844
Ensembl chr 3:46,016,990...46,085,825
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XDH
xanthine dehydrogenase
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XDH mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XDH mRNA]
CTD
PMID:23994337 PMID:34256052
NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742
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XPA
XPA, DNA damage recognition and repair factor
multiple interactions increases expression
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in decreased expression of XPA protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XPA protein
CTD
PMID:19553035
NCBI chr 9:97,654,398...97,697,340
Ensembl chr 9:97,674,909...97,697,340
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XPC
XPC complex subunit, DNA damage recognition and repair factor
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in decreased expression of XPC protein
CTD
PMID:19553035
NCBI chr 3:14,145,147...14,178,601
Ensembl chr 3:14,145,147...14,178,621
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YPEL1
yippee like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of YPEL1 mRNA
CTD
PMID:23994337
NCBI chr22:21,697,536...21,735,794
Ensembl chr22:21,697,536...21,735,794
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YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of YWHAB protein
CTD
PMID:23457121
NCBI chr20:44,885,705...44,908,532
Ensembl chr20:44,885,702...44,908,532
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YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of YWHAZ protein
CTD
PMID:23457121
NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388
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ZCCHC12
zinc finger CCHC-type containing 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZCCHC12 mRNA
CTD
PMID:23196670
NCBI chr X:118,823,824...118,826,968
Ensembl chr X:118,823,824...118,826,968
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ZDHHC2
zinc finger DHHC-type palmitoyltransferase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZDHHC2 mRNA
CTD
PMID:23196670
NCBI chr 8:17,156,482...17,224,799
Ensembl chr 8:17,156,482...17,224,799
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ZG16B
zymogen granule protein 16B
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZG16B mRNA
CTD
PMID:23146750
NCBI chr16:2,830,303...2,832,276
Ensembl chr16:2,830,253...2,839,585
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ZNF219
zinc finger protein 219
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ZFP219 mRNA
CTD
PMID:23994337
NCBI chr14:21,090,077...21,104,722
Ensembl chr14:21,090,077...21,104,722
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ZNF334
zinc finger protein 334
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZFP334 mRNA
CTD
PMID:32119087
NCBI chr20:46,462,313...46,513,559
Ensembl chr20:46,499,630...46,513,559
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ZNF354A
zinc finger protein 354A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZFP354A mRNA
CTD
PMID:20959002
NCBI chr 5:178,711,512...178,730,659
Ensembl chr 5:178,711,512...178,730,659
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ZNF367
zinc finger protein 367
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZFP367 mRNA
CTD
PMID:23196670
NCBI chr 9:96,385,941...96,418,370
Ensembl chr 9:96,385,941...96,418,370
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ZNF385D
zinc finger protein 385D
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZFP385D mRNA
CTD
PMID:23196670
NCBI chr 3:21,412,218...22,372,763
Ensembl chr 3:21,412,218...22,373,321
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ZNF395
zinc finger protein 395
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZNF395 mRNA
CTD
PMID:19692669
NCBI chr 8:28,345,590...28,386,460
Ensembl chr 8:28,345,590...28,402,701
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ZNF473
zinc finger protein 473
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZFP473 mRNA
CTD
PMID:32119087
NCBI chr19:50,026,005...50,048,776
Ensembl chr19:50,025,714...50,053,414
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ZNF697
zinc finger protein 697
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZNF697 mRNA
CTD
PMID:23146750
NCBI chr 1:119,619,377...119,648,266
Ensembl chr 1:119,619,377...119,648,266
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ZNF784
zinc finger protein 784
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZNF784 mRNA
CTD
PMID:23146750
NCBI chr19:55,620,741...55,624,566
Ensembl chr19:55,620,741...55,624,566
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ZNFX1
zinc finger NFX1-type containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZNFX1 mRNA
CTD
PMID:32119087
NCBI chr20:49,245,900...49,278,057
Ensembl chr20:49,237,946...49,278,426
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