GENE - CHEMICAL INTERACTIONS REPORT
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
A pentachlorobiphenyl that has formula C12H5Cl5.
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
multiple interactions ISO RGD:3757 6480464 CTD [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] affects the expression of SRD5A1 protein PMID:19464308 multiple interactions ISO RGD:3757 6480464 CTD [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SRD5A1 mRNA PMID:16984957 decreases expression ISO RGD:3757 6480464 CTD 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SRD5A1 mRNA PMID:20959002