Gene: CPOX (coproporphyrinogen oxidase)  Homo sapiens

Symbol: CPOX
Name: coproporphyrinogen oxidase
Description: The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).[provided by RefSeq, Oct 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: coprogen oxidase; coproporphyrinogen-III oxidase, mitochondrial; coproporphyrinogenase; COX; CPO; CPX; HCP; OTTHUMP00000217368
Orthologs: Rattus norvegicus : Cpox (coproporphyrinogen oxidase)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1398,275,063 - 98,289,228-NCBI
Human Genome Assembly HuRef395,670,419 - 95,684,588-NCBI
Human Genome Assembly GRCh37398,298,290 - 98,312,455-NCBI
Human Genome Assembly Build 36399,780,980 - 99,795,131-NCBI
Human Cytogenetic Map3q12 NCBI
Human Genome Assembly399,780,981 - 99,795,131 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on CPOX
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1323470
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2013-03-06
Status: ACTIVE