PTGER4 (prostaglandin E receptor 4 (subtype EP4))

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Keyword

Gene: PTGER4 (prostaglandin E receptor 4 (subtype EP4)) Homo sapiens

Symbol:

PTGER4

Name:

prostaglandin E receptor 4 (subtype EP4)

Description:

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

EP4; EP4R; MGC126583; OTTHUMP00000119996; PGE receptor EP4 subtype; PGE receptor, EP4 subtype; PGE2 receptor EP4 subtype; prostaglandin E2 receptor EP4 subtype; prostanoid EP4 receptor

Orthologs:

Mus musculus : Ptger4 (prostaglandin E receptor 4 (subtype EP4)) MGI
Rattus norvegicus : Ptger4 (prostaglandin E receptor 4 (subtype EP4))

Related Pseudogenes:

PTGER4P1 PTGER4P2 PTGER4P3

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	5	40,624,903 - 40,638,709	+	NCBI
Human Genome Assembly HuRef	5	40,632,020 - 40,645,825	+	NCBI
Human Genome Assembly GRCh37	5	40,680,032 - 40,693,837	+	NCBI
Human Genome Assembly Build 36	5	40,715,789 - 40,729,594	+	NCBI
Human Cytogenetic Map	5	p13.1		NCBI
Human Genome Assembly	5	40,715,788 - 40,729,592		NCBI