Gene: KCNJ12 (potassium inwardly-rectifying channel, subfamily J, member 12)
Homo sapiens
Symbol:
KCNJ12
Name:
potassium inwardly-rectifying channel, subfamily J, member 12
Description:
This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
ATP-sensitive inward rectifier potassium channel 12; FLJ14167; hIRK; hIRK1; hkir2.2x; inward rectifier K(+) channel Kir2.2; inward rectifier K(+) channel Kir2.2v; inward rectifier K(+) channel Kir2.6; IRK-2; IRK-2; IRK2; kcnj12x; KCNJ18; KCNJN1; Kir2.2; Kir2.2v; OTTHUMP00000162917; potassium channel, inwardly rectifying subfamily J member 12; potassium channel, inwardly rectifying subfamily J member 18; potassium inwardly-rectifying channel, subfamily J, inhibitor 1
Orthologs:
Mus musculus : Kcnj12
(potassium inwardly-rectifying channel, subfamily J, member 12)
MGI
Kcnj12
(potassium inwardly-rectifying channel, subfamily J, member 12)
Latest Assembly:
Human Genome Assembly GRCh37
Position:
Map Chr Position Strand Source Human Alternate Assembly CHM1_1 17 21,268,947 - 21,312,431 + NCBI Human Genome Assembly HuRef 17 20,481,596 - 20,525,235 + NCBI Human Genome Assembly GRCh37 17 21,279,699 - 21,323,179 + NCBI Human Genome Assembly Build 36 17 21,220,292 - 21,263,772 + NCBI Human Cytogenetic Map 17 p11.2 NCBI Human Genome Assembly 17 21,259,201 - 21,260,985 NCBI
Model
Gene Ontology Annotations
1298406 BP16_H Blood pressure QTL 16 (human) .0004 Blood pressure hypertension susceptibility 17 13105673 39105673 Human 1298468 BP34_H Blood pressure QTL 34 (human) 2.16 Blood pressure systolic 17 623167 66547903 Human 1298443 BP15_H Blood pressure QTL 15 (human) .025 Blood pressure hypertension susceptibility 17 171112 26171112 Human 1300020 BW31_H Body weight QTL 31 (human) 1.87 Body weight body mass index 17 4264550 30264550 Human 1300035 BW30_H Body weight QTL 30 (human) 2.47 Body weight body mass index 17 1 25806503 Human 1331651 COPD12_H Chronic obstructive pulmonary disease QTL 12 (human) 2.44 Chronic airflow obstruction post-bronchodilator FEV1/FVC 17 10859378 66547903 Human 1357357 BW56_H Body weight QTL 56 (human) 2.33 Body weight body mass index 17 19560307 45560307 Human 1357363 BW55_H Body weight QTL 55 (human) 1.34 Body weight body mass index 17 1 22823421 Human 1357311 AASTH13_H Allergic/atopic asthma related QTL 13 (human) 1.12 .016 Reversible airflow obstruction ETS positive 17 623167 26660190 Human 1559242 FBRL6_H Fibrinogen level QTL 6 (human) 1.5 Fibrinogen level 17 10859378 80253028 Human 1559262 SAPOB5_H Serum apolipoprotein B level QTL 5 (human) 3.7 .00009 Apolipoprotein level apolipoprotein B 17 17264482 38994609 Human 1559256 SCL59_H Serum cholesterol level QTL 59 (human) 2.48 Lipid level total cholesterol 17 16064515 80253028 Human 2289574 BW499_H Body weight QTL 499 (human) 1.96 Body weight BMI 17 18290029 44290029 Human 1643073 BW119_H Body Weight QTL 119 (human) 2.35 .0005 Body weight 17 15382302 41382302 Human 1643283 BW333_H Body Weight QTL 333 (human) 1.17 .01 Body weight body mass index 17 14260705 28382430 Human 1643577 GLUCO31_H Glucose level QTL 31 (human) .67 .04 Glucose level non-insulin-dependent 17 1260796 27260796 Human 1643382 BW310_H Body weight QTL 310 (human) 1.97 .0018 Body fat amount 17 15382302 41382302 Human 2293416 PRSTS282_H Prostate tumor susceptibility QTL 282 (human) Prostate tumor susceptibility 17 1 24845031 Human 2293362 PRSTS280_H Prostate tumor susceptibility QTL 280 (human) Prostate tumor susceptibility 17 1 24845031 Human 2314775 GLUCO99_H Glucose level QTL 99 (human) 3 .003 Glucose level non-insulin dependent 17 15382302 41382302 Human 2314769 GLUCO98_H Glucose level QTL 98 (human) 2.7 Glucose level non-insulin dependent 17 15382302 41382302 Human 2314774 GLUCO103_H Glucose level QTL 103 (human) 2.2 Glucose level non-insulin dependent 17 15382302 41382302 Human 2314767 GLUCO102_H Glucose level QTL 102 (human) 3 Glucose level non-insulin dependent 17 1 25806503 Human 2315776 GLUCO162_H Glucose level QTL 162 (human) 3.74 .000017 Glucose level 17 1260796 27260796 Human 2301156 PRSTS393_H Prostate tumor susceptibility QTL 393 (human) 2.28 Prostate tumor susceptibility 17 4264550 30264550 Human 2314750 GLUCO87_H Glucose level QTL 87 (human) .66 .021 Glucose level non-insulin dependent 17 1260796 27260796 Human 2301719 PRSTS419_H Prostate tumor susceptibility QTL 419 (human) 4.53 .004 Prostate tumor susceptibility 17 1 23859456 Human 2316054 GLUCO199_H Glucose level QTL 199 (human) .03 Glucose level 17 15209345 21531375 Human
Gene Ontology Annotations
