Gene: NT5E (5'-nucleotidase, ecto (CD73))  Homo sapiens

Symbol: NT5E
Name: 5'-nucleotidase, ecto (CD73)
Description: The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5 nucleotidase; 5' nucleotidase (CD73); 5'-NT; 5'-nucleotidase; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; NT5; NTE; OTTHUMP00000016808; Purine 5-Prime-Nucleotidase
Orthologs: Mus musculus : Nt5e (5' nucleotidase, ecto)  MGI
Rattus norvegicus : Nt5e (5' nucleotidase, ecto)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1686,139,106 - 86,185,316+NCBI
Human Genome Assembly HuRef683,383,590 - 83,429,793+NCBI
Human Genome Assembly GRCh37686,159,302 - 86,205,509+NCBI
Human Genome Assembly Build 36686,216,528 - 86,262,215+NCBI
Human Cytogenetic Map6q14-q21 NCBI
Human Genome Assembly686,216,527 - 86,262,215 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on NT5E
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 734028
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2013-04-16
Status: ACTIVE