DKK1 (dickkopf WNT signaling pathway inhibitor 1)

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Keyword

Gene: DKK1 (dickkopf WNT signaling pathway inhibitor 1) Homo sapiens

Symbol:

DKK1

Name:

dickkopf WNT signaling pathway inhibitor 1

Description:

This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

dickkopf 1 homolog; dickkopf related protein-1; dickkopf-1 like; dickkopf-like protein 1; dickkopf-related protein 1; DKK-1; hDkk-1; OTTHUMP00000019617; SK

Orthologs:

Mus musculus : Dkk1 (dickkopf homolog 1 (Xenopus laevis)) MGI
Rattus norvegicus : Dkk1 (dickkopf WNT signaling pathway inhibitor 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	10	54,458,925 - 54,462,301	+	NCBI
Human Genome Assembly HuRef	10	48,051,883 - 48,055,259	+	NCBI
Human Genome Assembly GRCh37	10	54,074,041 - 54,077,417	+	NCBI
Human Genome Assembly Build 36	10	53,744,047 - 53,747,423	+	NCBI
Human Cytogenetic Map	10	q11.2		NCBI
Human Genome Assembly	10	53,744,083 - 53,747,149		NCBI