TCF7L2 (transcription factor 7 like 2) - Rat Genome Database

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Gene: TCF7L2 (transcription factor 7 like 2) Homo sapiens
Analyze
Symbol: TCF7L2
Name: transcription factor 7 like 2
RGD ID: 1317786
HGNC Page HGNC:11641
Description: Enables several functions, including armadillo repeat domain binding activity; beta-catenin binding activity; and gamma-catenin binding activity. Involved in several processes, including positive regulation of heparan sulfate proteoglycan biosynthetic process; positive regulation of protein localization; and regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of beta-catenin-TCF7L2 complex and chromatin. Implicated in breast cancer; colorectal cancer; diabetes mellitus (multiple); pancreatic cancer; and prostate cancer. Biomarker of type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: HMG box transcription factor 4; hTCF-4; T-cell factor 4; T-cell factor-4 variant A; T-cell factor-4 variant B; T-cell factor-4 variant C; T-cell factor-4 variant D; T-cell factor-4 variant E; T-cell factor-4 variant F; T-cell factor-4 variant G; T-cell factor-4 variant H; T-cell factor-4 variant I; T-cell factor-4 variant J; T-cell factor-4 variant K; T-cell factor-4 variant L; T-cell factor-4 variant M; T-cell factor-4 variant X2; T-cell-specific transcription factor 4; TCF-4; TCF4; transcription factor 7-like 2; transcription factor 7-like 2 (T-cell specific, HMG-box)
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: TCF4 (Gene ID: 6925) and TCF7L2 (Gene ID: 6934) loci share the TCF4 symbol/alias in common. TCF4 is a widely used alternative name for T-cell-specific transcription factor 4 (TCF7L2) conflicting with the official symbol for transcription factor 4 (TCF4). [08 Feb 2019]
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810112,950,247 - 113,167,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10112,950,247 - 113,167,678 (+)EnsemblGRCh38hg38GRCh38
GRCh3710114,710,006 - 114,927,437 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610114,700,201 - 114,916,063 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410114,700,200 - 114,916,058NCBI
Celera10108,437,726 - 108,655,178 (+)NCBICelera
Cytogenetic Map10q25.2-q25.3NCBI
HuRef10108,337,509 - 108,554,907 (+)NCBIHuRef
CHM1_110114,992,047 - 115,209,474 (+)NCBICHM1_1
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (EXP,ISO)
acrolein  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (EXP)
AH23848  (EXP)
all-trans-retinoic acid  (EXP)
alpha-pinene  (EXP)
antirheumatic drug  (EXP)
aristolochic acid A  (EXP)
Aroclor 1254  (ISO)
arsenous acid  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (EXP)
buta-1,3-diene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
capecitabine  (EXP)
carbamazepine  (EXP)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chrysene  (ISO)
cisplatin  (EXP)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
curcumin  (EXP)
diarsenic trioxide  (EXP)
diclofenac  (EXP)
dicrotophos  (EXP)
diethylstilbestrol  (EXP)
dorsomorphin  (EXP)
doxorubicin  (ISO)
elemental selenium  (EXP)
epoxiconazole  (ISO)
folic acid  (ISO)
formaldehyde  (EXP)
furan  (ISO)
gallic acid  (EXP)
gentamycin  (ISO)
geraniol  (EXP)
indometacin  (EXP)
irinotecan  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP,ISO)
lithium chloride  (ISO)
menadione  (EXP)
methapyrilene  (ISO)
Morroniside  (ISO)
N,N-dimethylaniline  (EXP)
N-methyl-4-phenylpyridinium  (EXP,ISO)
nickel atom  (EXP)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
protein kinase inhibitor  (EXP)
quercetin  (EXP)
rac-lactic acid  (EXP)
resveratrol  (EXP)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
SB 431542  (EXP)
selenium atom  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
topotecan  (EXP,ISO)
trichostatin A  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (EXP)
vitamin E  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
blood vessel development  (IMP)
BMP signaling pathway  (ISO)
bone mineralization  (ISO)
canonical Wnt signaling pathway  (IBA,IC,IEA,IMP)
cellular response to starvation  (ISO)
embryonic digestive tract morphogenesis  (ISO)
embryonic genitalia morphogenesis  (ISO)
embryonic hindgut morphogenesis  (ISO)
epithelial cell proliferation  (ISO)
face morphogenesis  (ISO)
fat cell differentiation  (IDA)
fibroblast growth factor receptor signaling pathway  (ISO)
glucose homeostasis  (IDA,ISO)
glucose metabolic process  (ISO)
glycogen metabolic process  (ISO)
in utero embryonic development  (ISO)
insulin metabolic process  (ISO)
intracellular glucose homeostasis  (ISO)
maintenance of DNA repeat elements  (IMP)
multicellular organism growth  (ISO)
myoblast fate commitment  (IDA,ISO)
negative regulation of BMP signaling pathway  (ISO)
negative regulation of canonical Wnt signaling pathway  (IMP)
negative regulation of DNA-templated transcription  (IDA,IMP)
negative regulation of extrinsic apoptotic signaling pathway  (ISS)
negative regulation of fat cell differentiation  (ISO)
negative regulation of fibroblast growth factor receptor signaling pathway  (ISO)
negative regulation of gluconeogenesis  (IEA,ISO)
negative regulation of organ growth  (ISO)
negative regulation of transcription by RNA polymerase II  (IDA,IEA,ISO)
negative regulation of type B pancreatic cell apoptotic process  (ISS)
neural tube development  (ISO)
odontogenesis of dentin-containing tooth  (ISO)
oligodendrocyte development  (ISO)
organ growth  (ISO)
pancreas development  (TAS)
pituitary gland development  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of epithelial cell proliferation  (IMP,ISO)
positive regulation of epithelial to mesenchymal transition  (IMP)
positive regulation of gluconeogenesis  (ISO)
positive regulation of heparan sulfate proteoglycan biosynthetic process  (IMP)
positive regulation of insulin secretion  (IMP)
positive regulation of lipid biosynthetic process  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IMP)
positive regulation of protein localization to nucleus  (IMP)
positive regulation of transcription by RNA polymerase II  (IDA,ISO)
positive regulation of triglyceride biosynthetic process  (ISO)
post-embryonic development  (ISO)
regulation of DNA-templated transcription  (ISO)
regulation of gluconeogenesis  (ISO)
regulation of hormone metabolic process  (IDA)
regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
regulation of myelination  (ISO)
regulation of oligodendrocyte differentiation  (ISO)
regulation of skeletal muscle tissue development  (ISO)
regulation of smooth muscle cell proliferation  (IMP)
regulation of transcription by RNA polymerase II  (IBA,IDA,IEA)
response to glucose  (ISS)
secretory granule localization  (ISO)
skin development  (ISO)
somatic stem cell population maintenance  (ISO)
Wnt signaling pathway  (IEA)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis. Blackman SM, etal., Diabetologia. 2009 Sep;52(9):1858-65. Epub 2009 Jul 8.
2. Genetic interaction analysis of TCF7L2 for biochemical recurrence after radical prostatectomy in localized prostate cancer. Chen CS, etal., Int J Med Sci. 2015 Feb 5;12(3):243-7. doi: 10.7150/ijms.10953. eCollection 2015.
3. TCF7L2 type 2 diabetes risk variant, lifestyle factors, and incidence of prostate cancer. Drake I, etal., Prostate. 2014 Sep;74(12):1161-70. doi: 10.1002/pros.22832. Epub 2014 Jun 24.
4. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
5. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Jones S, etal., Science. 2008 Sep 26;321(5897):1801-6. Epub 2008 Sep 4.
6. Common type 2 diabetes risk gene variants associate with gestational diabetes. Lauenborg J, etal., J Clin Endocrinol Metab. 2009 Jan;94(1):145-50. Epub 2008 Nov 4.
7. A pathway-centric survey of somatic mutations in Chinese patients with colorectal carcinomas. Ling C, etal., PLoS One. 2015 Jan 24;10(1):e0116753. doi: 10.1371/journal.pone.0116753. eCollection 2015.
8. Genetic Variants of TCF7L2 are Associated with Insulin Resistance and Related Metabolic Phenotypes in Taiwanese Adolescents and Caucasian Young Adults. Liu PH, etal., J Clin Endocrinol Metab. 2009 Jun 9.
9. Meta-analysis of the association between SNPs in TCF7L2 and type 2 diabetes in East Asian population. Luo Y, etal., Diabetes Res Clin Pract. 2009 Aug;85(2):139-46. Epub 2009 May 30.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. TCF transcription factors: molecular switches in carcinogenesis. Roose J and Clevers H, Biochim Biophys Acta. 1999 Oct 29;1424(2-3):M23-37.
15. Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function. Shu L, etal., Hum Mol Genet. 2009 Jul 1;18(13):2388-99. Epub 2009 Apr 21.
16. Colorectal cancer susceptibility variants alter risk of breast cancer in a Chinese Han population. Wei W, etal., Genet Mol Res. 2013 Dec 4;12(4):6268-74. doi: 10.4238/2013.December.4.14.
17. Association and interaction analyses of genetic variants in ADIPOQ, ENPP1, GHSR, PPARgamma and TCF7L2 genes for diabetic nephropathy in a Taiwanese population with type 2 diabetes. Wu LS, etal., Nephrol Dial Transplant. 2009 Nov;24(11):3360-6. Epub 2009 Jun 8.
Additional References at PubMed
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PMID:23434931   PMID:23437103   PMID:23504200   PMID:23527206   PMID:23535729   PMID:23536853   PMID:23544013   PMID:23558246   PMID:23577093   PMID:23579632   PMID:23603903   PMID:23613959  
PMID:23617586   PMID:23648141   PMID:23651211   PMID:23670970   PMID:23840876   PMID:23844215   PMID:23855352   PMID:23926018   PMID:23935130   PMID:23942586   PMID:23945395   PMID:23951231  
PMID:23977356   PMID:24002895   PMID:24059590   PMID:24072042   PMID:24128935   PMID:24157263   PMID:24159190   PMID:24162774   PMID:24205231   PMID:24214952   PMID:24266846   PMID:24322204  
PMID:24354472   PMID:24390345   PMID:24463962   PMID:24485399   PMID:24509480   PMID:24518834   PMID:24529562   PMID:24574000   PMID:24589551   PMID:24605829   PMID:24611738   PMID:24639413  
PMID:24667787   PMID:24748645   PMID:24815492   PMID:24836286   PMID:24864085   PMID:24869759   PMID:24914535   PMID:24925104   PMID:24982424   PMID:25001176   PMID:25015099   PMID:25034524  
PMID:25048152   PMID:25058603   PMID:25102180   PMID:25117344   PMID:25131200   PMID:25185411   PMID:25185853   PMID:25224167   PMID:25274455   PMID:25299103   PMID:25301232   PMID:25311538  
PMID:25353718   PMID:25363768   PMID:25398947   PMID:25483087   PMID:25483131   PMID:25491720   PMID:25498973   PMID:25519018   PMID:25627047   PMID:25659031   PMID:25678248   PMID:25683913  
PMID:25863010   PMID:25867435   PMID:25934528   PMID:25946847   PMID:26046964   PMID:26058934   PMID:26102344   PMID:26109524   PMID:26247673   PMID:26273662   PMID:26316572   PMID:26345943  
PMID:26350900   PMID:26367734   PMID:26387539   PMID:26393635   PMID:26525881   PMID:26536002   PMID:26555947   PMID:26563606   PMID:26576435   PMID:26604685   PMID:26608632   PMID:26681031  
PMID:26822092   PMID:26823848   PMID:26845344   PMID:26914832   PMID:26934194   PMID:26947016   PMID:26958016   PMID:26986145   PMID:27013586   PMID:27014877   PMID:27027642   PMID:27046058  
PMID:27049325   PMID:27058589   PMID:27107012   PMID:27108846   PMID:27114453   PMID:27129219   PMID:27159876   PMID:27181358   PMID:27230431   PMID:27278879   PMID:27286737   PMID:27301468  
PMID:27310578   PMID:27323175   PMID:27430592   PMID:27465520   PMID:27480250   PMID:27504909   PMID:27605886   PMID:27639123   PMID:27684187   PMID:27706609   PMID:27738320   PMID:27755946  
PMID:27792933   PMID:27793664   PMID:27801786   PMID:27902311   PMID:27929407   PMID:27958632   PMID:27998387   PMID:28002648   PMID:28039460   PMID:28101933   PMID:28117551   PMID:28183453  
PMID:28192407   PMID:28220878   PMID:28253288   PMID:28254843   PMID:28263491   PMID:28277135   PMID:28299838   PMID:28320874   PMID:28404897   PMID:28420445   PMID:28430825   PMID:28450117  
PMID:28514442   PMID:28536608   PMID:28579156   PMID:28611053   PMID:28611215   PMID:28689657   PMID:28699988   PMID:28783164   PMID:28794006   PMID:28795454   PMID:28829046   PMID:28916740  
PMID:28921929   PMID:29025879   PMID:29171469   PMID:29174029   PMID:29180619   PMID:29182660   PMID:29301589   PMID:29317436   PMID:29325021   PMID:29326107   PMID:29331016   PMID:29395067  
PMID:29432739   PMID:29476053   PMID:29514658   PMID:29631902   PMID:29959006   PMID:29971604   PMID:29975781   PMID:30006590   PMID:30026326   PMID:30027476   PMID:30177026   PMID:30194258  
PMID:30266127   PMID:30275285   PMID:30290587   PMID:30467975   PMID:30557604   PMID:30585266   PMID:30614312   PMID:30614797   PMID:30656477   PMID:30682148   PMID:30702596   PMID:30718095  
PMID:30721637   PMID:30776466   PMID:30804502   PMID:30814579   PMID:30833792   PMID:30914432   PMID:30918250   PMID:31012334   PMID:31049566   PMID:31070566   PMID:31089877   PMID:31121319  
PMID:31125083   PMID:31211453   PMID:31288068   PMID:31288725   PMID:31300015   PMID:31340839   PMID:31392276   PMID:31409726   PMID:31436384   PMID:31470081   PMID:31492908   PMID:31504696  
PMID:31517619   PMID:31536510   PMID:31546272   PMID:31676834   PMID:31691451   PMID:31775533   PMID:31843716   PMID:31986371   PMID:32103169   PMID:32127821   PMID:32133972   PMID:32142998  
PMID:32182220   PMID:32203164   PMID:32265994   PMID:32296183   PMID:32344865   PMID:32372448   PMID:32403323   PMID:32445548   PMID:32513696   PMID:32564636   PMID:32572909   PMID:32651957  
PMID:32788279   PMID:32788640   PMID:32908242   PMID:33122478   PMID:33352264   PMID:33371788   PMID:33419631   PMID:33422939   PMID:33438217   PMID:33526767   PMID:33615650   PMID:33641658  
PMID:33644029   PMID:33752320   PMID:33761736   PMID:33784687   PMID:33903093   PMID:33961781   PMID:34001234   PMID:34003604   PMID:34016596   PMID:34079125   PMID:34200102   PMID:34232465  
PMID:34265237   PMID:34326068   PMID:34394276   PMID:34489551   PMID:34515148   PMID:34535768   PMID:34580284   PMID:34612510   PMID:34669858   PMID:34753394   PMID:34799688   PMID:34830370  
PMID:35044719   PMID:35096319   PMID:35140242   PMID:35154161   PMID:35234012   PMID:35279145   PMID:35341056   PMID:35442800   PMID:35477971   PMID:35596630   PMID:35636456   PMID:35677638  
PMID:35697299   PMID:35810738   PMID:35864968   PMID:35880246   PMID:35893034   PMID:35966063   PMID:35996498   PMID:36089195   PMID:36116131   PMID:36263318   PMID:36282337   PMID:36369331  
PMID:36609428   PMID:36724073   PMID:36734726   PMID:36800588   PMID:37234929   PMID:37308106   PMID:37392217   PMID:37606143   PMID:37689310   PMID:37879498   PMID:38072013   PMID:38166877  
PMID:38297188   PMID:38372101   PMID:38492104  


Genomics

Comparative Map Data
TCF7L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810112,950,247 - 113,167,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10112,950,247 - 113,167,678 (+)EnsemblGRCh38hg38GRCh38
GRCh3710114,710,006 - 114,927,437 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610114,700,201 - 114,916,063 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410114,700,200 - 114,916,058NCBI
Celera10108,437,726 - 108,655,178 (+)NCBICelera
Cytogenetic Map10q25.2-q25.3NCBI
HuRef10108,337,509 - 108,554,907 (+)NCBIHuRef
CHM1_110114,992,047 - 115,209,474 (+)NCBICHM1_1
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBIT2T-CHM13v2.0
Tcf7l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391955,730,227 - 55,922,091 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1955,730,252 - 55,922,086 (+)EnsemblGRCm39 Ensembl
GRCm381955,741,797 - 55,933,659 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1955,741,820 - 55,933,654 (+)EnsemblGRCm38mm10GRCm38
MGSCv371955,816,300 - 56,008,145 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361955,795,518 - 55,986,492 (+)NCBIMGSCv36mm8
Celera1957,933,629 - 58,125,906 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1951.59NCBI
Tcf7l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81264,791,335 - 264,984,225 (+)NCBIGRCr8
mRatBN7.21254,785,956 - 254,978,967 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1254,786,091 - 254,978,967 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1262,991,450 - 263,184,389 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01269,697,531 - 269,890,489 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01262,346,051 - 262,538,954 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01276,686,911 - 276,730,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1276,659,542 - 276,730,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1276,011,416 - 276,012,351 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01283,387,566 - 283,412,364 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01284,077,353 - 284,118,928 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41262,031,823 - 262,226,710 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1250,490,882 - 250,683,257 (+)NCBICelera
Cytogenetic Map1q55NCBI
Tcf7l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543118,020,409 - 18,209,134 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543118,020,309 - 18,207,926 (+)NCBIChiLan1.0ChiLan1.0
TCF7L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28124,826,392 - 125,043,998 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110124,831,339 - 125,049,334 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010109,541,524 - 109,759,499 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110112,991,588 - 113,193,992 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10112,978,167 - 113,192,281 (+)Ensemblpanpan1.1panPan2
TCF7L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12823,966,079 - 24,162,775 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2823,966,073 - 24,163,737 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2824,117,480 - 24,314,328 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02824,497,513 - 24,694,859 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2824,497,021 - 24,735,619 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12824,055,048 - 24,251,831 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02824,062,829 - 24,259,963 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02824,261,768 - 24,459,019 (+)NCBIUU_Cfam_GSD_1.0
Tcf7l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721321,900,727 - 22,087,420 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364863,473,843 - 3,660,576 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364863,473,877 - 3,660,565 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCF7L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14123,343,412 - 123,546,417 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114123,343,695 - 123,547,332 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214134,586,288 - 134,790,019 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TCF7L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19105,828,834 - 106,047,810 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604867,043,029 - 67,262,341 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tcf7l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473733,341,029 - 33,526,928 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473733,341,574 - 33,526,814 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TCF7L2
170 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001367943.1(TCF7L2):c.450+33966C>T single nucleotide variant Diabetes mellitus type 2, susceptibility to [RCV000007838] Chr10:112998590 [GRCh38]
Chr10:114758349 [GRCh37]
Chr10:10q25.2		 risk factor|drug response
NM_001367943.1(TCF7L2):c.552+9017G>T single nucleotide variant Diabetes mellitus type 2, susceptibility to [RCV000007839] Chr10:113049143 [GRCh38]
Chr10:114808902 [GRCh37]
Chr10:10q25.2		 risk factor
NM_001367943.1(TCF7L2):c.552+7162G>C single nucleotide variant Diabetes mellitus type 2, susceptibility to [RCV000007840] Chr10:113047288 [GRCh38]
Chr10:114807047 [GRCh37]
Chr10:10q25.2		 risk factor
GRCh38/hg38 10q23.33-25.3(chr10:95112607-116776637)x3 copy number gain See cases [RCV000050747] Chr10:95112607..116776637 [GRCh38]
Chr10:96872364..118383651 [GRCh37]
Chr10:96862354..118526138 [NCBI36]
Chr10:10q23.33-25.3		 pathogenic
GRCh38/hg38 10q25.2-26.3(chr10:111313099-133620674)x3 copy number gain See cases [RCV000051218] Chr10:111313099..133620674 [GRCh38]
Chr10:113072857..135434178 [GRCh37]
Chr10:113062847..135284168 [NCBI36]
Chr10:10q25.2-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.11(chr10:107191100-118761489)x1 copy number loss See cases [RCV000052570] Chr10:107191100..118761489 [GRCh38]
Chr10:108950858..120521001 [GRCh37]
Chr10:108940848..120510991 [NCBI36]
Chr10:10q25.1-26.11		 pathogenic
GRCh38/hg38 10q23.31-26.3(chr10:91048545-133620674)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|See cases [RCV000053560] Chr10:91048545..133620674 [GRCh38]
Chr10:92808302..135434178 [GRCh37]
Chr10:92798282..135284168 [NCBI36]
Chr10:10q23.31-26.3		 pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100194215-132432797)x3 copy number gain See cases [RCV000053564] Chr10:100194215..132432797 [GRCh38]
Chr10:101953972..134246301 [GRCh37]
Chr10:101943962..134096291 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.3(chr10:106925303-133620815)x3 copy number gain See cases [RCV000053588] Chr10:106925303..133620815 [GRCh38]
Chr10:108685061..135434319 [GRCh37]
Chr10:108675051..135284309 [NCBI36]
Chr10:10q25.1-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.3(chr10:108102587-133620674)x3 copy number gain See cases [RCV000133688] Chr10:108102587..133620674 [GRCh38]
Chr10:109862345..135434178 [GRCh37]
Chr10:109852335..135284168 [NCBI36]
Chr10:10q25.1-26.3		 pathogenic
GRCh38/hg38 10q25.2-25.3(chr10:112074094-115537174)x1 copy number loss See cases [RCV000135960] Chr10:112074094..115537174 [GRCh38]
Chr10:113833852..117032437 [GRCh37]
Chr10:113823842..117286674 [NCBI36]
Chr10:10q25.2-25.3		 pathogenic
GRCh38/hg38 10q25.2-26.12(chr10:112701186-120970617)x3 copy number gain See cases [RCV000137511] Chr10:112701186..120970617 [GRCh38]
Chr10:114460945..122730130 [GRCh37]
Chr10:114450935..122720120 [NCBI36]
Chr10:10q25.2-26.12		 likely pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100600492-133622588)x3 copy number gain See cases [RCV000137747] Chr10:100600492..133622588 [GRCh38]
Chr10:102360249..135436092 [GRCh37]
Chr10:102350239..135286082 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
GRCh38/hg38 10q25.2-25.3(chr10:110804735-114884010)x1 copy number loss See cases [RCV000139783] Chr10:110804735..114884010 [GRCh38]
Chr10:112564493..116643769 [GRCh37]
Chr10:112554483..116633759 [NCBI36]
Chr10:10q25.2-25.3		 likely pathogenic
GRCh38/hg38 10q24.32-25.3(chr10:102732173-114085105)x1 copy number loss See cases [RCV000143371] Chr10:102732173..114085105 [GRCh38]
Chr10:104491930..115844864 [GRCh37]
Chr10:104481920..115834854 [NCBI36]
Chr10:10q24.32-25.3		 pathogenic
NM_001367943.1(TCF7L2):c.552+46764_552+47838del deletion Normal pregnancy [RCV000161613] Chr10:113086890..113087964 [GRCh38]
Chr10:114846649..114847723 [GRCh37]
Chr10:10q25.2		 not provided
GRCh37/hg19 10q24.32-26.3(chr10:103288313-135512075)x3 copy number gain See cases [RCV000240457] Chr10:103288313..135512075 [GRCh37]
Chr10:10q24.32-26.3		 pathogenic
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143) copy number loss Distal 10q deletion syndrome [RCV003319583] Chr10:12829206..135427143 [GRCh37]
Chr10:10p13-q26.3		 pathogenic
GRCh37/hg19 10q24.32-26.3(chr10:104633712-135427143)x3 copy number gain See cases [RCV000449386] Chr10:104633712..135427143 [GRCh37]
Chr10:10q24.32-26.3		 pathogenic
GRCh37/hg19 10q24.2-26.3(chr10:100780957-135427143)x3 copy number gain See cases [RCV000446733] Chr10:100780957..135427143 [GRCh37]
Chr10:10q24.2-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q24.32-25.3(chr10:104030479-115410590)x1 copy number loss See cases [RCV000448581] Chr10:104030479..115410590 [GRCh37]
Chr10:10q24.32-25.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic|uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:106003533-135427143)x3 copy number gain See cases [RCV000510813] Chr10:106003533..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q23.32-26.3(chr10:93283493-135427143)x3 copy number gain See cases [RCV000510972] Chr10:93283493..135427143 [GRCh37]
Chr10:10q23.32-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3		 drug response
NM_001367943.1(TCF7L2):c.1565G>A (p.Arg522Gln) single nucleotide variant Inborn genetic diseases [RCV003306969] Chr10:113165677 [GRCh38]
Chr10:114925436 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.1246G>A (p.Gly416Ser) single nucleotide variant Inborn genetic diseases [RCV003273354] Chr10:113152417 [GRCh38]
Chr10:114912176 [GRCh37]
Chr10:10q25.3		 uncertain significance
GRCh37/hg19 10q24.33-26.3(chr10:105613040-135427143)x3 copy number gain not provided [RCV000683290] Chr10:105613040..135427143 [GRCh37]
Chr10:10q24.33-26.3		 pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:94346520-135427143)x3 copy number gain not provided [RCV000683291] Chr10:94346520..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
NM_001367943.1(TCF7L2):c.451-25857A>G single nucleotide variant not provided [RCV001668375] Chr10:113014168 [GRCh38]
Chr10:114773927 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.788+76TG[15] microsatellite not provided [RCV001644288] Chr10:113144101..113144106 [GRCh38]
Chr10:114903860..114903865 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.876-79dup duplication not provided [RCV001679264] Chr10:113150908..113150909 [GRCh38]
Chr10:114910667..114910668 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.1560T>A (p.Pro520=) single nucleotide variant not provided [RCV000929425] Chr10:113165672 [GRCh38]
Chr10:114925431 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.1536C>G (p.Pro512=) single nucleotide variant not provided [RCV000892397] Chr10:113165648 [GRCh38]
Chr10:114925407 [GRCh37]
Chr10:10q25.3		 benign|likely benign
NM_001367943.1(TCF7L2):c.219A>G (p.Glu73=) single nucleotide variant not provided [RCV000925190] Chr10:112951236 [GRCh38]
Chr10:114710995 [GRCh37]
Chr10:10q25.2		 likely benign
NM_001367943.1(TCF7L2):c.1534C>G (p.Pro512Ala) single nucleotide variant not provided [RCV000970465] Chr10:113165646 [GRCh38]
Chr10:114925405 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.1535C>G (p.Pro512Arg) single nucleotide variant not provided [RCV000971569] Chr10:113165647 [GRCh38]
Chr10:114925406 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.348C>T (p.Leu116=) single nucleotide variant not provided [RCV000949766] Chr10:112951574 [GRCh38]
Chr10:114711333 [GRCh37]
Chr10:10q25.2		 benign|likely benign
NM_001367943.1(TCF7L2):c.84G>A (p.Glu28=) single nucleotide variant not provided [RCV000879760] Chr10:112950840 [GRCh38]
Chr10:114710599 [GRCh37]
Chr10:10q25.2		 likely benign
NM_001367943.1(TCF7L2):c.1744C>A (p.Pro582Thr) single nucleotide variant TCF7L2-related condition [RCV003933067]|not provided [RCV000917687] Chr10:113165856 [GRCh38]
Chr10:114925615 [GRCh37]
Chr10:10q25.3		 benign|likely benign
GRCh37/hg19 10q25.1-26.3(chr10:110022170-135439095) copy number gain not provided [RCV000767665] Chr10:110022170..135439095 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
NM_001367943.1(TCF7L2):c.702G>A (p.Pro234=) single nucleotide variant TCF7L2-related condition [RCV003910635]|not provided [RCV000893310] Chr10:113143939 [GRCh38]
Chr10:114903698 [GRCh37]
Chr10:10q25.3		 likely benign
GRCh37/hg19 10q25.2-25.3(chr10:114666574-114942837)x1 copy number loss not provided [RCV000848563] Chr10:114666574..114942837 [GRCh37]
Chr10:10q25.2-25.3		 uncertain significance
GRCh37/hg19 10q25.2-26.3(chr10:114544537-135427143)x3 copy number gain not provided [RCV000847820] Chr10:114544537..135427143 [GRCh37]
Chr10:10q25.2-26.3		 pathogenic
NM_001367943.1(TCF7L2):c.1804T>C (p.Ser602Pro) single nucleotide variant not provided [RCV000962071] Chr10:113165916 [GRCh38]
Chr10:114925675 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.451-22060A>G single nucleotide variant not provided [RCV001641270] Chr10:113017965 [GRCh38]
Chr10:114777724 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.1639T>C (p.Ser547Pro) single nucleotide variant Inborn genetic diseases [RCV003251886] Chr10:113165751 [GRCh38]
Chr10:114925510 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.788+76TG[16] microsatellite not provided [RCV001673329] Chr10:113144101..113144104 [GRCh38]
Chr10:114903860..114903863 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.381+28C>A single nucleotide variant not provided [RCV001595150] Chr10:112951635 [GRCh38]
Chr10:114711394 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.1442+1770C>T single nucleotide variant not provided [RCV001690464] Chr10:113161762 [GRCh38]
Chr10:114921521 [GRCh37]
Chr10:10q25.3		 benign
NC_000010.11:g.112950166C>T single nucleotide variant not provided [RCV001659634] Chr10:112950166 [GRCh38]
Chr10:114709925 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.-497G>T single nucleotide variant not provided [RCV001598379] Chr10:112950260 [GRCh38]
Chr10:114710019 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.788+76TG[14] microsatellite not provided [RCV001615938] Chr10:113144101..113144108 [GRCh38]
Chr10:114903860..114903867 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.450+90A>G single nucleotide variant not provided [RCV001671472] Chr10:112964714 [GRCh38]
Chr10:114724473 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.553-316T>C single nucleotide variant not provided [RCV001649469] Chr10:113140868 [GRCh38]
Chr10:114900627 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.1442+1910G>T single nucleotide variant not provided [RCV001685738] Chr10:113161902 [GRCh38]
Chr10:114921661 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.381+311C>T single nucleotide variant not provided [RCV001654631] Chr10:112951918 [GRCh38]
Chr10:114711677 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.788+252G>A single nucleotide variant not provided [RCV001620624] Chr10:113144277 [GRCh38]
Chr10:114904036 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.*27T>C single nucleotide variant not provided [RCV001674792] Chr10:113165999 [GRCh38]
Chr10:114925758 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.788+76TG[13] microsatellite not provided [RCV001541522] Chr10:113144101..113144110 [GRCh38]
Chr10:114903860..114903869 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.45C>T (p.Asn15=) single nucleotide variant not provided [RCV000962054] Chr10:112950801 [GRCh38]
Chr10:114710560 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.1535C>A (p.Pro512His) single nucleotide variant not provided [RCV000950752] Chr10:113165647 [GRCh38]
Chr10:114925406 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.1737T>G (p.Ala579=) single nucleotide variant not provided [RCV000890808] Chr10:113165849 [GRCh38]
Chr10:114925608 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.381+10T>C single nucleotide variant not provided [RCV000911494] Chr10:112951617 [GRCh38]
Chr10:114711376 [GRCh37]
Chr10:10q25.2		 likely benign
NM_001367943.1(TCF7L2):c.553-1G>A single nucleotide variant not provided [RCV003230110] Chr10:113141183 [GRCh38]
Chr10:114900942 [GRCh37]
Chr10:10q25.3		 pathogenic
NM_001367943.1(TCF7L2):c.1219C>T (p.Arg407Ter) single nucleotide variant not provided [RCV003230111] Chr10:113152390 [GRCh38]
Chr10:114912149 [GRCh37]
Chr10:10q25.3		 pathogenic
NM_001367943.1(TCF7L2):c.876-307C>T single nucleotide variant not provided [RCV001717968] Chr10:113150691 [GRCh38]
Chr10:114910450 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.552+49468C>T single nucleotide variant not provided [RCV001678321] Chr10:113089594 [GRCh38]
Chr10:114849353 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.788+76TG[19] microsatellite not provided [RCV001678330] Chr10:113144100..113144101 [GRCh38]
Chr10:114903859..114903860 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.381+294dup duplication not provided [RCV001636483] Chr10:112951893..112951894 [GRCh38]
Chr10:114711652..114711653 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.788+76TG[17] microsatellite not provided [RCV001722830] Chr10:113144101..113144102 [GRCh38]
Chr10:114903860..114903861 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.1442+338A>G single nucleotide variant not provided [RCV001654654] Chr10:113160330 [GRCh38]
Chr10:114920089 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.-345del deletion not provided [RCV001687831] Chr10:112950404 [GRCh38]
Chr10:114710163 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.552+49514C>T single nucleotide variant not provided [RCV001717386] Chr10:113089640 [GRCh38]
Chr10:114849399 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.1269+335C>T single nucleotide variant not provided [RCV001639219] Chr10:113152775 [GRCh38]
Chr10:114912534 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.451-22114C>T single nucleotide variant not provided [RCV001641295] Chr10:113017911 [GRCh38]
Chr10:114777670 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.788+75_788+98del deletion not provided [RCV001598199] Chr10:113144089..113144112 [GRCh38]
Chr10:114903848..114903871 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.1498C>A (p.Pro500Thr) single nucleotide variant not provided [RCV001637699] Chr10:113165610 [GRCh38]
Chr10:114925369 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.685+126G>T single nucleotide variant not provided [RCV001654349] Chr10:113141442 [GRCh38]
Chr10:114901201 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.685+126del deletion not provided [RCV001618013] Chr10:113141436 [GRCh38]
Chr10:114901195 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.-294dup duplication not provided [RCV001687285] Chr10:112950449..112950450 [GRCh38]
Chr10:114710208..114710209 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.450+115A>G single nucleotide variant not provided [RCV001695505] Chr10:112964739 [GRCh38]
Chr10:114724498 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.450+90_450+92del deletion not provided [RCV001534070] Chr10:112964712..112964714 [GRCh38]
Chr10:114724471..114724473 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.451-22388C>T single nucleotide variant not provided [RCV001680959] Chr10:113017637 [GRCh38]
Chr10:114777396 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.451-14360G>A single nucleotide variant not provided [RCV001679184] Chr10:113025665 [GRCh38]
Chr10:114785424 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.381+309dup duplication not provided [RCV001694768] Chr10:112951913..112951914 [GRCh38]
Chr10:114711672..114711673 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.450+188del deletion not provided [RCV001648554] Chr10:112964812 [GRCh38]
Chr10:114724571 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.451-25858C>T single nucleotide variant not provided [RCV001679601] Chr10:113014167 [GRCh38]
Chr10:114773926 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.1370-197A>G single nucleotide variant not provided [RCV001714042] Chr10:113159723 [GRCh38]
Chr10:114919482 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.451-22127G>A single nucleotide variant not provided [RCV001651726] Chr10:113017898 [GRCh38]
Chr10:114777657 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.397G>A (p.Gly133Ser) single nucleotide variant Intellectual disability [RCV001255105]|not provided [RCV001358450] Chr10:112964571 [GRCh38]
Chr10:114724330 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.875+1G>C single nucleotide variant Neurodevelopmental abnormality [RCV001264698] Chr10:113146098 [GRCh38]
Chr10:114905857 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.84G>C (p.Glu28Asp) single nucleotide variant not provided [RCV001356059] Chr10:112950840 [GRCh38]
Chr10:114710599 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.450+117_450+118insATGGTGGTG insertion not provided [RCV001527746] Chr10:112964739..112964740 [GRCh38]
Chr10:114724498..114724499 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.450+154A>G single nucleotide variant not provided [RCV001674541] Chr10:112964778 [GRCh38]
Chr10:114724537 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.450+137TGG[4] microsatellite not provided [RCV001640891] Chr10:112964761..112964763 [GRCh38]
Chr10:114724520..114724522 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.1001+197T>C single nucleotide variant not provided [RCV001538902] Chr10:113151320 [GRCh38]
Chr10:114911079 [GRCh37]
Chr10:10q25.3		 benign
NM_001367943.1(TCF7L2):c.190-89del deletion not provided [RCV001694005] Chr10:112951111 [GRCh38]
Chr10:114710870 [GRCh37]
Chr10:10q25.2		 benign
NM_001367943.1(TCF7L2):c.1197del (p.Tyr400fs) deletion Neurodevelopmental abnormality [RCV001754559] Chr10:113152368 [GRCh38]
Chr10:114912127 [GRCh37]
Chr10:10q25.3		 likely pathogenic
GRCh37/hg19 10q24.32-25.3(chr10:104030479-115410590) copy number loss not specified [RCV002052885] Chr10:104030479..115410590 [GRCh37]
Chr10:10q24.32-25.3		 pathogenic
GRCh37/hg19 10q25.1-26.3(chr10:108455687-135427143) copy number gain not specified [RCV002052891] Chr10:108455687..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q25.1-25.3(chr10:107092654-117852548)x1 copy number loss not provided [RCV001827678] Chr10:107092654..117852548 [GRCh37]
Chr10:10q25.1-25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1543A>C (p.Asn515His) single nucleotide variant Inborn genetic diseases [RCV003276275] Chr10:113165655 [GRCh38]
Chr10:114925414 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.450+33966C>G single nucleotide variant Type 2 diabetes mellitus [RCV002259421] Chr10:112998590 [GRCh38]
Chr10:114758349 [GRCh37]
Chr10:10q25.2		 likely risk allele
NM_001367943.1(TCF7L2):c.723del (p.Tyr242fs) deletion Neurodevelopmental delay [RCV002274381] Chr10:113143960 [GRCh38]
Chr10:114903719 [GRCh37]
Chr10:10q25.3		 likely pathogenic
NM_001367943.1(TCF7L2):c.1592C>A (p.Thr531Asn) single nucleotide variant not provided [RCV003233406] Chr10:113165704 [GRCh38]
Chr10:114925463 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1162-7C>A single nucleotide variant TCF7L2-related Intellectual disability [RCV002266716] Chr10:113152326 [GRCh38]
Chr10:114912085 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.755_762del (p.Gln252fs) deletion Inborn genetic diseases [RCV002860657] Chr10:113143991..113143998 [GRCh38]
Chr10:114903750..114903757 [GRCh37]
Chr10:10q25.3		 pathogenic
NM_001367943.1(TCF7L2):c.1534C>A (p.Pro512Thr) single nucleotide variant Inborn genetic diseases [RCV002684370] Chr10:113165646 [GRCh38]
Chr10:114925405 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.552+49416T>A single nucleotide variant Inborn genetic diseases [RCV002818306] Chr10:113089542 [GRCh38]
Chr10:114849301 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.409T>C (p.Tyr137His) single nucleotide variant Inborn genetic diseases [RCV002860855] Chr10:112964583 [GRCh38]
Chr10:114724342 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.552+49329C>T single nucleotide variant Inborn genetic diseases [RCV002844117] Chr10:113089455 [GRCh38]
Chr10:114849214 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.1545C>G (p.Asn515Lys) single nucleotide variant Inborn genetic diseases [RCV002924258] Chr10:113165657 [GRCh38]
Chr10:114925416 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1766T>C (p.Ile589Thr) single nucleotide variant not provided [RCV002756769] Chr10:113165878 [GRCh38]
Chr10:114925637 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1714G>A (p.Ala572Thr) single nucleotide variant Inborn genetic diseases [RCV002691670] Chr10:113165826 [GRCh38]
Chr10:114925585 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1754C>T (p.Pro585Leu) single nucleotide variant Inborn genetic diseases [RCV002821905] Chr10:113165866 [GRCh38]
Chr10:114925625 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1634A>G (p.His545Arg) single nucleotide variant Inborn genetic diseases [RCV002768222] Chr10:113165746 [GRCh38]
Chr10:114925505 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1729C>G (p.Pro577Ala) single nucleotide variant Inborn genetic diseases [RCV002803008] Chr10:113165841 [GRCh38]
Chr10:114925600 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1180G>T (p.Glu394Ter) single nucleotide variant Inborn genetic diseases [RCV002697024] Chr10:113152351 [GRCh38]
Chr10:114912110 [GRCh37]
Chr10:10q25.3		 pathogenic
NM_001367943.1(TCF7L2):c.527G>A (p.Arg176Gln) single nucleotide variant Inborn genetic diseases [RCV002675194] Chr10:113040101 [GRCh38]
Chr10:114799860 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.1556C>T (p.Ser519Phe) single nucleotide variant Inborn genetic diseases [RCV002921109] Chr10:113165668 [GRCh38]
Chr10:114925427 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1700T>G (p.Leu567Arg) single nucleotide variant Inborn genetic diseases [RCV002935700] Chr10:113165812 [GRCh38]
Chr10:114925571 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1778C>G (p.Ser593Trp) single nucleotide variant Inborn genetic diseases [RCV002809836] Chr10:113165890 [GRCh38]
Chr10:114925649 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.451-6C>T single nucleotide variant Inborn genetic diseases [RCV002657072]|TCF7L2-related condition [RCV003953980] Chr10:113040019 [GRCh38]
Chr10:114799778 [GRCh37]
Chr10:10q25.2		 likely benign
NM_001367943.1(TCF7L2):c.1774C>T (p.Pro592Ser) single nucleotide variant not provided [RCV003228394] Chr10:113165886 [GRCh38]
Chr10:114925645 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1222C>T (p.Gln408Ter) single nucleotide variant not provided [RCV003228395] Chr10:113152393 [GRCh38]
Chr10:114912152 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1060C>T (p.Leu354Phe) single nucleotide variant not provided [RCV003228406] Chr10:113151783 [GRCh38]
Chr10:114911542 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.777G>T (p.Trp259Cys) single nucleotide variant Inborn genetic diseases [RCV003215744] Chr10:113144014 [GRCh38]
Chr10:114903773 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1144C>T (p.Gln382Ter) single nucleotide variant Autism [RCV003223494] Chr10:113151867 [GRCh38]
Chr10:114911626 [GRCh37]
Chr10:10q25.3		 pathogenic
NM_001367943.1(TCF7L2):c.1141A>C (p.Asn381His) single nucleotide variant not provided [RCV003228403] Chr10:113151864 [GRCh38]
Chr10:114911623 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1268A>G (p.Tyr423Cys) single nucleotide variant not provided [RCV003228405] Chr10:113152439 [GRCh38]
Chr10:114912198 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.565C>T (p.Pro189Ser) single nucleotide variant Inborn genetic diseases [RCV003266154] Chr10:113141196 [GRCh38]
Chr10:114900955 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.916A>T (p.Thr306Ser) single nucleotide variant Inborn genetic diseases [RCV003286336] Chr10:113151038 [GRCh38]
Chr10:114910797 [GRCh37]
Chr10:10q25.3		 uncertain significance
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143) copy number gain Distal trisomy 10q [RCV003319593] Chr10:11138692..135427143 [GRCh37]
Chr10:10p14-q26.3		 pathogenic
NM_001367943.1(TCF7L2):c.1542G>C (p.Pro514=) single nucleotide variant not provided [RCV003422890] Chr10:113165654 [GRCh38]
Chr10:114925413 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.150T>A (p.Asn50Lys) single nucleotide variant Inborn genetic diseases [RCV003357233] Chr10:112950906 [GRCh38]
Chr10:114710665 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.547A>G (p.Ile183Val) single nucleotide variant Inborn genetic diseases [RCV003344432] Chr10:113040121 [GRCh38]
Chr10:114799880 [GRCh37]
Chr10:10q25.2		 likely benign
NM_001367943.1(TCF7L2):c.1813G>C (p.Gly605Arg) single nucleotide variant Inborn genetic diseases [RCV003365191] Chr10:113165925 [GRCh38]
Chr10:114925684 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1203G>C (p.Glu401Asp) single nucleotide variant Inborn genetic diseases [RCV003376024] Chr10:113152374 [GRCh38]
Chr10:114912133 [GRCh37]
Chr10:10q25.3		 uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:111378692-135427143)x3 copy number gain Distal trisomy 10q [RCV003458955] Chr10:111378692..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q25.2(chr10:114608930-114787637)x1 copy number loss not provided [RCV003483106] Chr10:114608930..114787637 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.82G>C (p.Glu28Gln) single nucleotide variant not provided [RCV003422884] Chr10:112950838 [GRCh38]
Chr10:114710597 [GRCh37]
Chr10:10q25.2		 uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:111447991-133435388)x3 copy number gain not provided [RCV003484817] Chr10:111447991..133435388 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
NM_001367943.1(TCF7L2):c.855C>T (p.Thr285=) single nucleotide variant not provided [RCV003422887] Chr10:113146077 [GRCh38]
Chr10:114905836 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.1152T>G (p.Leu384=) single nucleotide variant not provided [RCV003422889] Chr10:113151875 [GRCh38]
Chr10:114911634 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.1653G>A (p.Pro551=) single nucleotide variant TCF7L2-related condition [RCV003954114]|not provided [RCV003422891] Chr10:113165765 [GRCh38]
Chr10:114925524 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.1002-6C>T single nucleotide variant not provided [RCV003422888] Chr10:113151719 [GRCh38]
Chr10:114911478 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.200G>A (p.Arg67Gln) single nucleotide variant not provided [RCV003422885] Chr10:112951217 [GRCh38]
Chr10:114710976 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.816G>A (p.Thr272=) single nucleotide variant not provided [RCV003422886] Chr10:113146038 [GRCh38]
Chr10:114905797 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.1776G>A (p.Pro592=) single nucleotide variant not provided [RCV003422892] Chr10:113165888 [GRCh38]
Chr10:114925647 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.288G>T (p.Lys96Asn) single nucleotide variant Intellectual disability [RCV003458321] Chr10:112951514 [GRCh38]
Chr10:114711273 [GRCh37]
Chr10:10q25.2		 uncertain significance
GRCh37/hg19 10q25.1-26.13(chr10:107129993-123817654)x3 copy number gain not specified [RCV003986891] Chr10:107129993..123817654 [GRCh37]
Chr10:10q25.1-26.13		 likely pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:95078198-135427143)x3 copy number gain not specified [RCV003986893] Chr10:95078198..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
NM_001367943.1(TCF7L2):c.1542G>A (p.Pro514=) single nucleotide variant not provided [RCV003885926] Chr10:113165654 [GRCh38]
Chr10:114925413 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.1680C>T (p.Ala560=) single nucleotide variant TCF7L2-related condition [RCV003964745] Chr10:113165792 [GRCh38]
Chr10:114925551 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.296C>A (p.Pro99Gln) single nucleotide variant TCF7L2-related condition [RCV003944315] Chr10:112951522 [GRCh38]
Chr10:114711281 [GRCh37]
Chr10:10q25.2		 uncertain significance
NM_001367943.1(TCF7L2):c.940A>G (p.Ile314Val) single nucleotide variant not provided [RCV003886659] Chr10:113151062 [GRCh38]
Chr10:114910821 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1254C>T (p.Ser418=) single nucleotide variant TCF7L2-related condition [RCV003969826] Chr10:113152425 [GRCh38]
Chr10:114912184 [GRCh37]
Chr10:10q25.3		 likely benign
NM_001367943.1(TCF7L2):c.528G>A (p.Arg176=) single nucleotide variant TCF7L2-related condition [RCV003914181] Chr10:113040102 [GRCh38]
Chr10:114799861 [GRCh37]
Chr10:10q25.2		 likely benign
NM_001367943.1(TCF7L2):c.1459G>A (p.Val487Ile) single nucleotide variant not provided [RCV003885291] Chr10:113165571 [GRCh38]
Chr10:114925330 [GRCh37]
Chr10:10q25.3		 uncertain significance
NM_001367943.1(TCF7L2):c.1570G>A (p.Ala524Thr) single nucleotide variant TCF7L2-related condition [RCV003979681] Chr10:113165682 [GRCh38]
Chr10:114925441 [GRCh37]
Chr10:10q25.3		 benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:9520
Count of miRNA genes:1102
Interacting mature miRNAs:1345
Transcripts:ENST00000277945, ENST00000346198, ENST00000349937, ENST00000352065, ENST00000355717, ENST00000355995, ENST00000369386, ENST00000369389, ENST00000369395, ENST00000369397, ENST00000466338, ENST00000470254, ENST00000471569, ENST00000476887, ENST00000480888, ENST00000494353, ENST00000534894, ENST00000536810, ENST00000538897, ENST00000542695, ENST00000543371, ENST00000545257
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D10S168  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,745,515 - 114,745,679UniSTSGRCh37
Celera10108,473,297 - 108,473,461UniSTS
Cytogenetic Map10q25.3UniSTS
Cytogenetic Map10q25.2UniSTS
HuRef10108,372,773 - 108,372,935UniSTS
Marshfield Genetic Map10130.9RGD
Marshfield Genetic Map10130.9UniSTS
deCODE Assembly Map10130.05UniSTS
Whitehead-YAC Contig Map10 UniSTS
WI-20234  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,925,776 - 114,926,044UniSTSGRCh37
Build 3610114,915,766 - 114,916,034RGDNCBI36
Celera10108,653,516 - 108,653,784RGD
Cytogenetic Map10q25.3UniSTS
GeneMap99-GB4 RH Map10515.11UniSTS
Whitehead-RH Map10621.5UniSTS
SHGC-6704  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,838,979 - 114,839,174UniSTSGRCh37
Build 3610114,828,969 - 114,829,164RGDNCBI36
Celera10108,566,763 - 108,566,958RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,466,576 - 108,466,771UniSTS
G43540  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,927,289 - 114,927,418UniSTSGRCh37
Build 3610114,917,279 - 114,917,408RGDNCBI36
Celera10108,655,030 - 108,655,159RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,554,759 - 108,554,888UniSTS
RH102533  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,748,868 - 114,749,052UniSTSGRCh37
Build 3610114,738,858 - 114,739,042RGDNCBI36
Celera10108,476,650 - 108,476,834RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,376,123 - 108,376,307UniSTS
GeneMap99-GB4 RH Map10517.09UniSTS
SHGC-112532  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,887,646 - 114,887,926UniSTSGRCh37
Build 3610114,877,636 - 114,877,916RGDNCBI36
Celera10108,615,386 - 108,615,666RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,515,117 - 108,515,397UniSTS
TNG Radiation Hybrid Map1055903.0UniSTS
SHGC-144967  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,795,176 - 114,795,497UniSTSGRCh37
Build 3610114,785,166 - 114,785,487RGDNCBI36
Celera10108,522,950 - 108,523,271RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,422,431 - 108,422,752UniSTS
TNG Radiation Hybrid Map1055849.0UniSTS
STS-T81462  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,924,139 - 114,924,273UniSTSGRCh37
Build 3610114,914,129 - 114,914,263RGDNCBI36
Celera10108,651,879 - 108,652,013RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,551,609 - 108,551,743UniSTS
GeneMap99-GB4 RH Map10517.2UniSTS
SHGC-33545  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,924,179 - 114,924,328UniSTSGRCh37
Build 3610114,914,169 - 114,914,318RGDNCBI36
Celera10108,651,919 - 108,652,068RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,551,649 - 108,551,798UniSTS
TNG Radiation Hybrid Map1055884.0UniSTS
Stanford-G3 RH Map105229.0UniSTS
GeneMap99-GB4 RH Map10517.42UniSTS
Whitehead-RH Map10620.3UniSTS
NCBI RH Map101234.5UniSTS
GeneMap99-G3 RH Map105465.0UniSTS
RH48450  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,868,979 - 114,869,119UniSTSGRCh37
Build 3610114,858,969 - 114,859,109RGDNCBI36
Celera10108,596,758 - 108,596,898RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,496,540 - 108,496,680UniSTS
GeneMap99-GB4 RH Map10545.6UniSTS
NCBI RH Map101208.8UniSTS
SHGC-58284  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,859,590 - 114,859,747UniSTSGRCh37
Build 3610114,849,580 - 114,849,737RGDNCBI36
Celera10108,587,361 - 108,587,518RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,487,144 - 108,487,301UniSTS
TNG Radiation Hybrid Map1055894.0UniSTS
RH66532  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,732,757 - 114,732,922UniSTSGRCh37
Build 3610114,722,747 - 114,722,912RGDNCBI36
Celera10108,460,539 - 108,460,704RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,360,013 - 108,360,178UniSTS
GeneMap99-GB4 RH Map10517.39UniSTS
STS-T97004  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,739,863 - 114,740,018UniSTSGRCh37
GRCh3710114,739,844 - 114,740,035UniSTSGRCh37
Build 3610114,729,853 - 114,730,008RGDNCBI36
Celera10108,467,626 - 108,467,817UniSTS
Celera10108,467,645 - 108,467,800RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,367,121 - 108,367,276UniSTS
HuRef10108,367,102 - 108,367,293UniSTS
GeneMap99-GB4 RH Map10517.52UniSTS
RH11324  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,927,151 - 114,927,300UniSTSGRCh37
Build 3610114,917,141 - 114,917,290RGDNCBI36
Celera10108,654,892 - 108,655,041RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,554,621 - 108,554,770UniSTS
GeneMap99-GB4 RH Map10515.64UniSTS
D10S1597  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,741,796 - 114,742,046UniSTSGRCh37
Build 3610114,731,786 - 114,732,036RGDNCBI36
Celera10108,469,578 - 108,469,828RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,369,054 - 108,369,304UniSTS
Whitehead-YAC Contig Map10 UniSTS
G20756  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,925,921 - 114,926,039UniSTSGRCh37
Build 3610114,915,911 - 114,916,029RGDNCBI36
Celera10108,653,661 - 108,653,779RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,553,390 - 108,553,508UniSTS
A006F09  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,925,921 - 114,926,039UniSTSGRCh37
Build 3610114,915,911 - 114,916,029RGDNCBI36
Celera10108,653,661 - 108,653,779RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,553,390 - 108,553,508UniSTS
GeneMap99-GB4 RH Map10517.39UniSTS
D10S2296  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710114,717,839 - 114,718,080UniSTSGRCh37
Build 3610114,707,829 - 114,708,070RGDNCBI36
Celera10108,445,621 - 108,445,862RGD
Cytogenetic Map10q25.3UniSTS
HuRef10108,345,366 - 108,345,607UniSTS
Whitehead-YAC Contig Map10 UniSTS
STS-T97004  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10q25.3UniSTS
GeneMap99-GB4 RH Map10514.18UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2110 1387 1116 366 445 240 3403 794 987 205 1134 1493 137 1191 1962 3
Low 329 1574 610 258 1119 225 954 1403 2743 214 324 119 38 1 13 826 2 2
Below cutoff 29 356 3 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_012631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001146274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001146283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001146284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001146285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001146286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001198525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001198526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001198527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001198528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001198529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001198530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001198531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001349871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001363501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_030756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB034691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB440195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB451266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF522996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ270770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ270771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ270772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ270773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ270774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ270775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ270776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ270777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ270778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK074705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK225809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL135792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL158212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL445486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL451084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM701919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ900611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU619467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR536574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA394991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA473655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA590466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ010174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM352851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT583969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF772717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF772718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y11306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z99386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000277945   ⟹   ENSP00000277945
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,250 - 113,166,312 (+)Ensembl
RefSeq Acc Id: ENST00000346198   ⟹   ENSP00000345640
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,916 - 113,141,316 (+)Ensembl
RefSeq Acc Id: ENST00000349937   ⟹   ENSP00000298692
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,125,536 - 113,165,648 (+)Ensembl
RefSeq Acc Id: ENST00000352065   ⟹   ENSP00000344823
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,660 - 113,165,612 (+)Ensembl
RefSeq Acc Id: ENST00000355717   ⟹   ENSP00000347949
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,586 - 113,165,972 (+)Ensembl
RefSeq Acc Id: ENST00000355995   ⟹   ENSP00000348274
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,247 - 113,167,678 (+)Ensembl
RefSeq Acc Id: ENST00000369386   ⟹   ENSP00000358393
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,151,083 - 113,166,324 (+)Ensembl
RefSeq Acc Id: ENST00000369389   ⟹   ENSP00000358396
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,126,690 - 113,165,612 (+)Ensembl
RefSeq Acc Id: ENST00000369395   ⟹   ENSP00000358402
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,660 - 113,165,612 (+)Ensembl
RefSeq Acc Id: ENST00000369397   ⟹   ENSP00000358404
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,452 - 113,167,678 (+)Ensembl
RefSeq Acc Id: ENST00000466338   ⟹   ENSP00000490260
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,151,771 - 113,166,309 (+)Ensembl
RefSeq Acc Id: ENST00000470254   ⟹   ENSP00000435694
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,151,831 - 113,165,940 (+)Ensembl
RefSeq Acc Id: ENST00000471569
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,157,773 - 113,165,587 (+)Ensembl
RefSeq Acc Id: ENST00000480888   ⟹   ENSP00000490004
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,152,414 - 113,165,961 (+)Ensembl
RefSeq Acc Id: ENST00000494353
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,161,231 - 113,165,681 (+)Ensembl
RefSeq Acc Id: ENST00000534894   ⟹   ENSP00000443626
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,250 - 113,167,678 (+)Ensembl
RefSeq Acc Id: ENST00000536810   ⟹   ENSP00000446238
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,250 - 113,167,678 (+)Ensembl
RefSeq Acc Id: ENST00000538897   ⟹   ENSP00000446172
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,250 - 113,167,678 (+)Ensembl
RefSeq Acc Id: ENST00000542695   ⟹   ENSP00000443883
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,250 - 113,167,678 (+)Ensembl
RefSeq Acc Id: ENST00000543371   ⟹   ENSP00000444972
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,250 - 113,167,678 (+)Ensembl
RefSeq Acc Id: ENST00000545257   ⟹   ENSP00000440547
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,664 - 113,166,160 (+)Ensembl
RefSeq Acc Id: ENST00000627217   ⟹   ENSP00000486891
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,247 - 113,167,678 (+)Ensembl
RefSeq Acc Id: ENST00000629706   ⟹   ENSP00000487507
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,757 - 113,165,972 (+)Ensembl
RefSeq Acc Id: ENST00000636236
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,129,646 - 113,151,087 (+)Ensembl
RefSeq Acc Id: ENST00000636309
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,132,022 - 113,151,758 (+)Ensembl
RefSeq Acc Id: ENST00000636447
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,129,206 - 113,151,057 (+)Ensembl
RefSeq Acc Id: ENST00000636585
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,132,896 - 113,146,094 (+)Ensembl
RefSeq Acc Id: ENST00000637321
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,126,022 - 113,151,023 (+)Ensembl
RefSeq Acc Id: ENST00000637416
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,126,957 - 113,151,766 (+)Ensembl
RefSeq Acc Id: ENST00000637574   ⟹   ENSP00000490478
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,129,357 - 113,158,717 (+)Ensembl
RefSeq Acc Id: ENST00000704414   ⟹   ENSP00000515891
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10112,950,757 - 113,165,748 (+)Ensembl
RefSeq Acc Id: ENST00000704415
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,126,957 - 113,167,668 (+)Ensembl
RefSeq Acc Id: ENST00000704420   ⟹   ENSP00000515894
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,126,848 - 113,165,705 (+)Ensembl
RefSeq Acc Id: ENST00000704421
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,132,948 - 113,165,656 (+)Ensembl
RefSeq Acc Id: ENST00000704422   ⟹   ENSP00000515895
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10113,141,220 - 113,165,622 (+)Ensembl
RefSeq Acc Id: NM_001146274   ⟹   NP_001139746
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001146283   ⟹   NP_001139755
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001146284   ⟹   NP_001139756
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001146285   ⟹   NP_001139757
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001146286   ⟹   NP_001139758
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001198525   ⟹   NP_001185454
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001198526   ⟹   NP_001185455
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001198527   ⟹   NP_001185456
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001198528   ⟹   NP_001185457
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001198529   ⟹   NP_001185458
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001198530   ⟹   NP_001185459
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001198531   ⟹   NP_001185460
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349870   ⟹   NP_001336799
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810113,129,271 - 113,167,678 (+)NCBI
T2T-CHM13v2.010114,020,549 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001349871   ⟹   NP_001336800
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810113,126,633 - 113,167,678 (+)NCBI
T2T-CHM13v2.010114,017,911 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001363501   ⟹   NP_001350430
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001367943   ⟹   NP_001354872
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
RefSeq Acc Id: NM_030756   ⟹   NP_110383
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 113,167,678 (+)NCBI
GRCh3710114,709,978 - 114,927,437 (+)NCBI
Build 3610114,700,201 - 114,916,063 (+)NCBI Archive
HuRef10108,337,509 - 108,554,907 (+)ENTREZGENE
CHM1_110114,992,047 - 115,209,474 (+)NCBI
T2T-CHM13v2.010113,841,538 - 114,058,955 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001139746 (Get FASTA)   NCBI Sequence Viewer  
  NP_001139755 (Get FASTA)   NCBI Sequence Viewer  
  NP_001139756 (Get FASTA)   NCBI Sequence Viewer  
  NP_001139757 (Get FASTA)   NCBI Sequence Viewer  
  NP_001139758 (Get FASTA)   NCBI Sequence Viewer  
  NP_001185454 (Get FASTA)   NCBI Sequence Viewer  
  NP_001185455 (Get FASTA)   NCBI Sequence Viewer  
  NP_001185456 (Get FASTA)   NCBI Sequence Viewer  
  NP_001185457 (Get FASTA)   NCBI Sequence Viewer  
  NP_001185458 (Get FASTA)   NCBI Sequence Viewer  
  NP_001185459 (Get FASTA)   NCBI Sequence Viewer  
  NP_001185460 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336799 (Get FASTA)   NCBI Sequence Viewer  
  NP_001336800 (Get FASTA)   NCBI Sequence Viewer  
  NP_001350430 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354872 (Get FASTA)   NCBI Sequence Viewer  
  NP_110383 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH32656 (Get FASTA)   NCBI Sequence Viewer  
  AAQ08860 (Get FASTA)   NCBI Sequence Viewer  
  ACI28522 (Get FASTA)   NCBI Sequence Viewer  
  ACI28523 (Get FASTA)   NCBI Sequence Viewer  
  ACI28524 (Get FASTA)   NCBI Sequence Viewer  
  ACI28525 (Get FASTA)   NCBI Sequence Viewer  
  ACI28526 (Get FASTA)   NCBI Sequence Viewer  
  ACI28527 (Get FASTA)   NCBI Sequence Viewer  
  ACI28528 (Get FASTA)   NCBI Sequence Viewer  
  ACI28529 (Get FASTA)   NCBI Sequence Viewer  
  ACI28530 (Get FASTA)   NCBI Sequence Viewer  
  ACI28531 (Get FASTA)   NCBI Sequence Viewer  
  ACI28532 (Get FASTA)   NCBI Sequence Viewer  
  ADK35174 (Get FASTA)   NCBI Sequence Viewer  
  ADK35175 (Get FASTA)   NCBI Sequence Viewer  
  ADK35176 (Get FASTA)   NCBI Sequence Viewer  
  ADK35177 (Get FASTA)   NCBI Sequence Viewer  
  ADK35178 (Get FASTA)   NCBI Sequence Viewer  
  ADK35179 (Get FASTA)   NCBI Sequence Viewer  
  ADK35180 (Get FASTA)   NCBI Sequence Viewer  
  ADK35181 (Get FASTA)   NCBI Sequence Viewer  
  ADK35182 (Get FASTA)   NCBI Sequence Viewer  
  ADK35183 (Get FASTA)   NCBI Sequence Viewer  
  ADK35184 (Get FASTA)   NCBI Sequence Viewer  
  ADK35185 (Get FASTA)   NCBI Sequence Viewer  
  ADK35186 (Get FASTA)   NCBI Sequence Viewer  
  ADK35187 (Get FASTA)   NCBI Sequence Viewer  
  AXC43357 (Get FASTA)   NCBI Sequence Viewer  
  AXC43358 (Get FASTA)   NCBI Sequence Viewer  
  BAA86225 (Get FASTA)   NCBI Sequence Viewer  
  BAG51988 (Get FASTA)   NCBI Sequence Viewer  
  BAG59004 (Get FASTA)   NCBI Sequence Viewer  
  BAG61310 (Get FASTA)   NCBI Sequence Viewer  
  BAG62997 (Get FASTA)   NCBI Sequence Viewer  
  BAG64677 (Get FASTA)   NCBI Sequence Viewer  
  BAG70080 (Get FASTA)   NCBI Sequence Viewer  
  BAH14482 (Get FASTA)   NCBI Sequence Viewer  
  BAH24004 (Get FASTA)   NCBI Sequence Viewer  
  CAA72166 (Get FASTA)   NCBI Sequence Viewer  
  CAB97212 (Get FASTA)   NCBI Sequence Viewer  
  CAB97213 (Get FASTA)   NCBI Sequence Viewer  
  CAB97214 (Get FASTA)   NCBI Sequence Viewer  
  CAB97215 (Get FASTA)   NCBI Sequence Viewer  
  CAB97216 (Get FASTA)   NCBI Sequence Viewer  
  CAB97217 (Get FASTA)   NCBI Sequence Viewer  
  CAB97218 (Get FASTA)   NCBI Sequence Viewer  
  CAB97219 (Get FASTA)   NCBI Sequence Viewer  
  CAG38811 (Get FASTA)   NCBI Sequence Viewer  
  EAW49506 (Get FASTA)   NCBI Sequence Viewer  
  EAW49507 (Get FASTA)   NCBI Sequence Viewer  
  EAW49508 (Get FASTA)   NCBI Sequence Viewer  
  EAW49509 (Get FASTA)   NCBI Sequence Viewer  
  EAW49510 (Get FASTA)   NCBI Sequence Viewer  
  EAW49511 (Get FASTA)   NCBI Sequence Viewer  
  EAW49512 (Get FASTA)   NCBI Sequence Viewer  
  EAW49513 (Get FASTA)   NCBI Sequence Viewer  
  EAW49514 (Get FASTA)   NCBI Sequence Viewer  
  EAW49515 (Get FASTA)   NCBI Sequence Viewer  
  EAW49516 (Get FASTA)   NCBI Sequence Viewer  
  EAW49517 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000277945
  ENSP00000277945.8
  ENSP00000298692.6
  ENSP00000344823
  ENSP00000344823.5
  ENSP00000345640.4
  ENSP00000347949
  ENSP00000347949.4
  ENSP00000348274
  ENSP00000348274.4
  ENSP00000358393.2
  ENSP00000358396
  ENSP00000358396.3
  ENSP00000358402
  ENSP00000358402.2
  ENSP00000358404
  ENSP00000358404.4
  ENSP00000435694.1
  ENSP00000440547
  ENSP00000440547.2
  ENSP00000443626
  ENSP00000443626.2
  ENSP00000446172
  ENSP00000446172.1
  ENSP00000486891
  ENSP00000486891.1
  ENSP00000487507
  ENSP00000487507.1
  ENSP00000490004.1
  ENSP00000490478
  ENSP00000490478.2
  ENSP00000515891
  ENSP00000515891.1
  ENSP00000515894.1
  ENSP00000515895.1
GenBank Protein Q9NQB0 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001139746   ⟸   NM_001146274
- Peptide Label: isoform 1
- UniProtKB: A0A2Z5HTM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001185460   ⟸   NM_001198531
- Peptide Label: isoform 13
- UniProtKB: E2GH15 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001139755   ⟸   NM_001146283
- Peptide Label: isoform 3
- UniProtKB: C6ZRK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001185454   ⟸   NM_001198525
- Peptide Label: isoform 7
- UniProtKB: C6ZRJ7 (UniProtKB/TrEMBL),   C6ZRK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001185457   ⟸   NM_001198528
- Peptide Label: isoform 10
- UniProtKB: C6ZRK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_110383   ⟸   NM_030756
- Peptide Label: isoform 2
- UniProtKB: Q6FHW4 (UniProtKB/TrEMBL),   E2GH23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001185458   ⟸   NM_001198529
- Peptide Label: isoform 11
- UniProtKB: A0A994J711 (UniProtKB/TrEMBL),   C6ZRK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001139757   ⟸   NM_001146285
- Peptide Label: isoform 5
- UniProtKB: C6ZRK5 (UniProtKB/TrEMBL),   Q5JRY5 (UniProtKB/TrEMBL),   E2GH23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001185455   ⟸   NM_001198526
- Peptide Label: isoform 8
- UniProtKB: E2GH23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001139758   ⟸   NM_001146286
- Peptide Label: isoform 6
- UniProtKB: C6ZRK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001185456   ⟸   NM_001198527
- Peptide Label: isoform 9
- UniProtKB: Q5VVR7 (UniProtKB/TrEMBL),   C6ZRJ9 (UniProtKB/TrEMBL),   C6ZRK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001139756   ⟸   NM_001146284
- Peptide Label: isoform 4
- UniProtKB: C6ZRK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001185459   ⟸   NM_001198530
- Peptide Label: isoform 12
- UniProtKB: A0A0A0MTL7 (UniProtKB/TrEMBL),   C6ZRK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001336800   ⟸   NM_001349871
- Peptide Label: isoform 15
- UniProtKB: B7Z9Z6 (UniProtKB/TrEMBL),   Q5JRY4 (UniProtKB/TrEMBL),   Q5VVR8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001336799   ⟸   NM_001349870
- Peptide Label: isoform 14
- UniProtKB: B4DJZ2 (UniProtKB/TrEMBL),   A0A1B0GVE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001354872   ⟸   NM_001367943
- Peptide Label: isoform 17
- UniProtKB: Q9NQB7 (UniProtKB/Swiss-Prot),   Q9NQB6 (UniProtKB/Swiss-Prot),   Q9NQB5 (UniProtKB/Swiss-Prot),   Q9NQB4 (UniProtKB/Swiss-Prot),   Q9NQB3 (UniProtKB/Swiss-Prot),   Q9NQB2 (UniProtKB/Swiss-Prot),   Q9NQB1 (UniProtKB/Swiss-Prot),   Q9NQB0 (UniProtKB/Swiss-Prot),   O00185 (UniProtKB/Swiss-Prot),   F8W7T5 (UniProtKB/Swiss-Prot),   F8W742 (UniProtKB/Swiss-Prot),   E9PFH9 (UniProtKB/Swiss-Prot),   E2GH25 (UniProtKB/Swiss-Prot),   E2GH24 (UniProtKB/Swiss-Prot),   E2GH20 (UniProtKB/Swiss-Prot),   E2GH19 (UniProtKB/Swiss-Prot),   E2GH14 (UniProtKB/Swiss-Prot),   C6ZRK0 (UniProtKB/Swiss-Prot),   C6ZRJ8 (UniProtKB/Swiss-Prot),   B9X074 (UniProtKB/Swiss-Prot),   B4DRJ8 (UniProtKB/Swiss-Prot),   Q9ULC2 (UniProtKB/Swiss-Prot),   E2GH23 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001350430   ⟸   NM_001363501
- Peptide Label: isoform 16
- UniProtKB: E2GH15 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSP00000443883   ⟸   ENST00000542695
RefSeq Acc Id: ENSP00000345640   ⟸   ENST00000346198
RefSeq Acc Id: ENSP00000444972   ⟸   ENST00000543371
RefSeq Acc Id: ENSP00000490478   ⟸   ENST00000637574
RefSeq Acc Id: ENSP00000440547   ⟸   ENST00000545257
RefSeq Acc Id: ENSP00000490260   ⟸   ENST00000466338
RefSeq Acc Id: ENSP00000298692   ⟸   ENST00000349937
RefSeq Acc Id: ENSP00000490004   ⟸   ENST00000480888
RefSeq Acc Id: ENSP00000486891   ⟸   ENST00000627217
RefSeq Acc Id: ENSP00000443626   ⟸   ENST00000534894
RefSeq Acc Id: ENSP00000446238   ⟸   ENST00000536810
RefSeq Acc Id: ENSP00000487507   ⟸   ENST00000629706
RefSeq Acc Id: ENSP00000344823   ⟸   ENST00000352065
RefSeq Acc Id: ENSP00000435694   ⟸   ENST00000470254
RefSeq Acc Id: ENSP00000446172   ⟸   ENST00000538897
RefSeq Acc Id: ENSP00000348274   ⟸   ENST00000355995
RefSeq Acc Id: ENSP00000347949   ⟸   ENST00000355717
RefSeq Acc Id: ENSP00000358404   ⟸   ENST00000369397
RefSeq Acc Id: ENSP00000358402   ⟸   ENST00000369395
RefSeq Acc Id: ENSP00000358396   ⟸   ENST00000369389
RefSeq Acc Id: ENSP00000358393   ⟸   ENST00000369386
RefSeq Acc Id: ENSP00000277945   ⟸   ENST00000277945
RefSeq Acc Id: ENSP00000515894   ⟸   ENST00000704420
RefSeq Acc Id: ENSP00000515891   ⟸   ENST00000704414
RefSeq Acc Id: ENSP00000515895   ⟸   ENST00000704422
Protein Domains
CTNNB1 binding N-teminal   HMG box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NQB0-F1-model_v2 AlphaFold Q9NQB0 1-619 view protein structure

Promoters
RGD ID:7218699
Promoter ID:EPDNEW_H15095
Type:initiation region
Name:TCF7L2_1
Description:transcription factor 7 like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15096  EPDNEW_H15097  EPDNEW_H15098  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,247 - 112,950,307EPDNEW
RGD ID:7218701
Promoter ID:EPDNEW_H15096
Type:initiation region
Name:TCF7L2_4
Description:transcription factor 7 like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15095  EPDNEW_H15097  EPDNEW_H15098  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,361 - 112,950,421EPDNEW
RGD ID:7218703
Promoter ID:EPDNEW_H15097
Type:initiation region
Name:TCF7L2_2
Description:transcription factor 7 like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15095  EPDNEW_H15096  EPDNEW_H15098  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,493 - 112,950,553EPDNEW
RGD ID:7218705
Promoter ID:EPDNEW_H15098
Type:initiation region
Name:TCF7L2_3
Description:transcription factor 7 like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15095  EPDNEW_H15096  EPDNEW_H15097  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810112,950,671 - 112,950,731EPDNEW
RGD ID:6788304
Promoter ID:HG_KWN:11204
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour,   HeLa_S3,   K562,   NB4
Transcripts:ENST00000277945,   ENST00000340914,   ENST00000346198,   ENST00000349937,   ENST00000352065,   ENST00000355717,   ENST00000355995,   ENST00000369395,   NM_001146274,   NM_001146283,   NM_001146284,   NM_001146285,   NM_001146286,   OTTHUMT00000050412,   OTTHUMT00000050413
Position:
Human AssemblyChrPosition (strand)Source
Build 3610114,699,916 - 114,700,662 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11641 AgrOrtholog
COSMIC TCF7L2 COSMIC
Ensembl Genes ENSG00000148737 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000277945 ENTREZGENE
  ENST00000277945.12 UniProtKB/TrEMBL
  ENST00000346198.5 UniProtKB/TrEMBL
  ENST00000349937.8 UniProtKB/TrEMBL
  ENST00000352065 ENTREZGENE
  ENST00000352065.10 UniProtKB/Swiss-Prot
  ENST00000355717 ENTREZGENE
  ENST00000355717.9 UniProtKB/Swiss-Prot
  ENST00000355995 ENTREZGENE
  ENST00000355995.9 UniProtKB/Swiss-Prot
  ENST00000369386.5 UniProtKB/TrEMBL
  ENST00000369389 ENTREZGENE
  ENST00000369389.7 UniProtKB/TrEMBL
  ENST00000369395 ENTREZGENE
  ENST00000369395.6 UniProtKB/TrEMBL
  ENST00000369397 ENTREZGENE
  ENST00000369397.8 UniProtKB/Swiss-Prot
  ENST00000470254.1 UniProtKB/TrEMBL
  ENST00000480888.1 UniProtKB/TrEMBL
  ENST00000534894 ENTREZGENE
  ENST00000534894.5 UniProtKB/TrEMBL
  ENST00000538897 ENTREZGENE
  ENST00000538897.5 UniProtKB/Swiss-Prot
  ENST00000545257 ENTREZGENE
  ENST00000545257.6 UniProtKB/TrEMBL
  ENST00000627217 ENTREZGENE
  ENST00000627217.3 UniProtKB/Swiss-Prot
  ENST00000629706 ENTREZGENE
  ENST00000629706.2 UniProtKB/TrEMBL
  ENST00000637574 ENTREZGENE
  ENST00000637574.2 UniProtKB/TrEMBL
  ENST00000704414 ENTREZGENE
  ENST00000704414.1 UniProtKB/TrEMBL
  ENST00000704420.1 UniProtKB/TrEMBL
  ENST00000704422.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.900.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000148737 GTEx
HGNC ID HGNC:11641 ENTREZGENE
Human Proteome Map TCF7L2 Human Proteome Map
InterPro Catenin_binding_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTNNB1-bd_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HMG_box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TCF/LEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:6934 UniProtKB/Swiss-Prot
NCBI Gene 6934 ENTREZGENE
OMIM 602228 OMIM
PANTHER PTHR10373 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR 7-LIKE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CTNNB1_binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HMG_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA36394 PharmGKB
PROSITE HMG_BOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART c-clamp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HMG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MTL7 ENTREZGENE, UniProtKB/TrEMBL
  A0A0D9SGH8_HUMAN UniProtKB/TrEMBL
  A0A1B0GU84_HUMAN UniProtKB/TrEMBL
  A0A1B0GVE1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2Z5HTM8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2Z5HTN9_HUMAN UniProtKB/TrEMBL
  A0A994J4F0_HUMAN UniProtKB/TrEMBL
  A0A994J711 ENTREZGENE, UniProtKB/TrEMBL
  B4DJZ2 ENTREZGENE, UniProtKB/TrEMBL
  B4DRJ8 ENTREZGENE
  B5BU30_HUMAN UniProtKB/TrEMBL
  B7Z9Z6 ENTREZGENE
  B9X074 ENTREZGENE
  C6ZRJ7 ENTREZGENE, UniProtKB/TrEMBL
  C6ZRJ8 ENTREZGENE
  C6ZRJ9 ENTREZGENE
  C6ZRK0 ENTREZGENE
  C6ZRK1 ENTREZGENE, UniProtKB/TrEMBL
  C6ZRK2 ENTREZGENE, UniProtKB/TrEMBL
  C6ZRK5 ENTREZGENE, UniProtKB/TrEMBL
  E2GH13_HUMAN UniProtKB/TrEMBL
  E2GH14 ENTREZGENE
  E2GH15 ENTREZGENE, UniProtKB/TrEMBL
  E2GH16_HUMAN UniProtKB/TrEMBL
  E2GH18_HUMAN UniProtKB/TrEMBL
  E2GH19 ENTREZGENE
  E2GH20 ENTREZGENE
  E2GH23 ENTREZGENE, UniProtKB/TrEMBL
  E2GH24 ENTREZGENE
  E2GH25 ENTREZGENE
  E2GH26_HUMAN UniProtKB/TrEMBL
  E9PFH9 ENTREZGENE
  F8W742 ENTREZGENE
  F8W7T5 ENTREZGENE
  H0YEE5_HUMAN UniProtKB/TrEMBL
  O00185 ENTREZGENE
  Q5JRY3_HUMAN UniProtKB/TrEMBL
  Q5JRY4 ENTREZGENE, UniProtKB/TrEMBL
  Q5JRY5 ENTREZGENE
  Q5VVR5_HUMAN UniProtKB/TrEMBL
  Q5VVR7 ENTREZGENE, UniProtKB/TrEMBL
  Q5VVR8 ENTREZGENE, UniProtKB/TrEMBL
  Q6FHW4 ENTREZGENE, UniProtKB/TrEMBL
  Q9NQB0 ENTREZGENE
  Q9NQB1 ENTREZGENE
  Q9NQB2 ENTREZGENE
  Q9NQB3 ENTREZGENE
  Q9NQB4 ENTREZGENE
  Q9NQB5 ENTREZGENE
  Q9NQB6 ENTREZGENE
  Q9NQB7 ENTREZGENE
  Q9ULC2 ENTREZGENE
  TF7L2_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B4DRJ8 UniProtKB/Swiss-Prot
  B7Z9Z6 UniProtKB/TrEMBL
  B9X074 UniProtKB/Swiss-Prot
  C6ZRJ8 UniProtKB/Swiss-Prot
  C6ZRJ9 UniProtKB/TrEMBL
  C6ZRK0 UniProtKB/Swiss-Prot
  E2GH14 UniProtKB/Swiss-Prot
  E2GH19 UniProtKB/Swiss-Prot
  E2GH20 UniProtKB/Swiss-Prot
  E2GH24 UniProtKB/Swiss-Prot
  E2GH25 UniProtKB/Swiss-Prot
  E9PFH9 UniProtKB/Swiss-Prot
  F8W742 UniProtKB/Swiss-Prot
  F8W7T5 UniProtKB/Swiss-Prot
  O00185 UniProtKB/Swiss-Prot
  Q5JRY5 UniProtKB/TrEMBL
  Q9NQB1 UniProtKB/Swiss-Prot
  Q9NQB2 UniProtKB/Swiss-Prot
  Q9NQB3 UniProtKB/Swiss-Prot
  Q9NQB4 UniProtKB/Swiss-Prot
  Q9NQB5 UniProtKB/Swiss-Prot
  Q9NQB6 UniProtKB/Swiss-Prot
  Q9NQB7 UniProtKB/Swiss-Prot
  Q9ULC2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-10 TCF7L2  transcription factor 7 like 2  TCF7L2  transcription factor 7-like 2 (T-cell specific, HMG-box)  Symbol and/or name change 5135510 APPROVED