Gene: CROCC (ciliary rootlet coiled-coil, rootletin)
Homo sapiens
Symbol:
CROCC
Name:
ciliary rootlet coiled-coil, rootletin
Description:
ENCODES a protein that exhibits kinesin binding (ortholog); structural molecule activity (ortholog); INVOLVED IN centrosome organization; protein localization; FOUND IN actin cytoskeleton; centrosome; cytoplasm; INTERACTS WITH 5-aza-2'-deoxycytidine; zinc atom; zinc(0)
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
ciliary rootlet coiled-coil protein; KIAA0445; OTTHUMP00000002222; OTTHUMP00000002223; ROLT; rootletin; rootletin, ciliary rootlet protein; Tax1-binding protein 2
Orthologs:
Mus musculus : Crocc
(ciliary rootlet coiled-coil, rootletin)
MGI
Rattus norvegicus : Crocc
(ciliary rootlet coiled-coil, rootletin)
Related Pseudogenes:
CROCCP1
CROCCP2
CROCCP3
CROCCP4
CROCCP5
Latest Assembly:
Human Genome Assembly GRCh37
Position:
Map Chr Position Strand Source Human Alternate Assembly CHM1_1 1 17,454,561 - 17,505,589 + NCBI Human Genome Assembly HuRef 1 15,492,380 - 15,543,555 + NCBI Human Genome Assembly GRCh37 1 17,248,445 - 17,299,474 + NCBI Human Celera Assembly 1 15,570,790 - 15,621,812 + NCBI Human Genome Assembly Build 36 1 17,121,032 - 17,172,061 + NCBI Human Cytogenetic Map 1 p36.13 NCBI Human Genome Assembly 1 16,993,750 - 17,044,766 NCBI
Model
Gene Ontology Annotations
Biological Process
cell cycle IEA UniProtKB-KW:KW-0131 2290271 GO_REF:0000037 UniProtKB GO_REF:0000037 cell projection organization IEA UniProtKB-KW:KW-0970 2290271 GO_REF:0000037 UniProtKB GO_REF:0000037 centrosome organization IEA InterPro:IPR026733 2290271 GO_REF:0000002 InterPro GO_REF:0000002 centrosome organization IDA 2290271 PMID:16203858 UniProtKB PMID:16203858 protein localization IMP 2290271 PMID:18086858 UniProtKB PMID:18086858
1559394 SCL111_H Serum cholesterol level QTL 111 (human) 2.43 Lipid level LDL cholesterol 1 1 19962115 Human 2289215 BW344_H Body weight QTL 344 (human) .0499 Body fat amount percent fat 1 1 20142514 Human 1298433 BP17_H Blood pressure QTL 17 (human) .0162 Blood pressure hypertension susceptibility 1 1 21118041 Human 1298451 OSTEAR17_H Osteoarthritis QTL 17 (human) 2.4 .0004 Joint/bone inflammation osteoarthritis 11 1 25248168 Human 1298463 BP9_H Blood pressure QTL 9 (human) 3.9 Blood pressure hypertension susceptibility 1 1 25248168 Human 1643556 GLUCO11_H Glucose level QTL 11 (human) .77 .03 Glucose level non-insulin-dependent 1 784271 26784271 Human 1643571 GLUCO12_H Glucose level QTL 12 (human) .019 Glucose level non-insulin-dependent 1 784271 26784271 Human 2292920 PRSTS119_H Prostate tumor susceptibility QTL 119 (human) 2.13 .02 Prostate tumor susceptibility 1 784271 26784271 Human 2293430 PRSTS243_H Prostate tumor susceptibility QTL 243 (human) .077 Prostate tumor susceptibility 1 784271 26784271 Human 2292926 PRSTS121_H Prostate tumor susceptibility QTL 121 (human) 3.22 Prostate tumor susceptibility 1 2028868 28028868 Human 1331652 COPD17_H Chronic obstructive pulmonary disease QTL 17 (human) 1.28 Chronic airflow obstruction FEV1 1 3584957 17783848 Human 2293440 PRSTS240_H Prostate tumor susceptibility QTL 240 (human) .016 Prostate tumor susceptibility 1 3584957 17783848 Human 2316874 GLUCO301_H Glucose level QTL 301 (human) .001 Glucose level 1 4783758 30783758 Human 2314559 INSUL2_H Insulin level QTL 2 (human) 1 .039 Insulin level fasting 1 6026613 32026613 Human 1358848 MULTSCL16_H Multiple sclerosis susceptibility QTL 16 (human) Multiple sclerosis susceptibility 1 6267090 32267090 Human 2289594 BW463_H Body weight QTL 463 (human) 2.1 Body fat amount abdominal 1 6957083 32957083 Human 1643585 SGHRL1_H Serum ghrelin level QTL 1 (human) 3.2 .00006 Hormone level ghrelin level 1 11487038 37649865 Human 1576325 MYI1_H Myocardial infarction susceptibility QTL 1 (human) 11.68 .000000000001 Myocardial infarction susceptibility early-onset 1 13784187 34553372 Human 1576329 MYI9_H Myocardial infarction susceptibility QTL 9 (human) 12 Myocardial infarction susceptibility early-onset 1 13784187 34553372 Human 2289524 BW435_H Body weight QTL 435 (human) 1.38 Body weight BMI 1 16419541 19957148 Human