Gene: ALOX15 (arachidonate 15-lipoxygenase)  Homo sapiens

Symbol: ALOX15
Name: arachidonate 15-lipoxygenase
Description: ENCODES a protein that exhibits arachidonate 15-lipoxygenase activity (inferred); eoxin A4 synthase activity (inferred); iron ion binding (inferred); INVOLVED IN arachidonic acid metabolic process (inferred); bone mineralization (inferred); inflammatory response (inferred); PARTICIPATES IN interleukin-4 signaling pathway; atherosclerosis pathway; lipoxygenase mediated pathway of arachidonic acid metabolism; ASSOCIATED WITH Alzheimer Disease; Nasal Polyps; Acute Lung Injury (ortholog); FOUND IN cytoplasm; nucleus; INTERACTS WITH all-trans-retinoic acid; arachidonic acid; cis-caffeic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 15-lipooxygenase-1; 15-LOX; 15-LOX-1; 15-LOX2; 15LOX-1; arachidonate 15-lipoxygenase; arachidonate omega-6 lipoxygenase; OTTHUMP00000115936
Orthologs: Mus musculus : Alox15 (arachidonate 15-lipoxygenase)  MGI
Rattus norvegicus : Alox15 (arachidonate 15-lipoxygenase)
Related Pseudogenes: ALOX15P1   ALOX15P2  
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1174,520,600 - 4,531,349-NCBI
Human Genome Assembly HuRef174,423,571 - 4,434,147-NCBI
Human Genome Assembly GRCh37174,534,214 - 4,544,960-NCBI
Human Genome Assembly Build 36174,480,963 - 4,491,709-NCBI
Human Cytogenetic Map17p13.3 NCBI
Human Genome Assembly174,480,964 - 4,491,709 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on ALOX15
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1352372
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2013-05-14
Status: ACTIVE