Gene: SULF1 (sulfatase 1)  Homo sapiens
Symbol: SULF1
Name: sulfatase 1
Description: Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: extracellular sulfatase Sulf-1; FLJ30905; FLJ38022; FLJ41750; HSULF-1; KIAA1077; OTTHUMP00000226760; OTTHUMP00000226761; OTTHUMP00000226762; SULF-1; sulfatase FP
Orthologs: Mus musculus : Sulf1 (sulfatase 1)  MGI
Rattus norvegicus : Sulf1 (sulfatase 1)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1870,480,404 - 70,674,665+NCBI
Human Genome Assembly HuRef865,873,300 - 66,067,259+NCBI
Human Genome Assembly GRCh37870,378,859 - 70,573,147+NCBI
Human Genome Assembly Build 36870,541,427 - 70,735,701+NCBI
Human Cytogenetic Map8q13.1 NCBI
Human Genome Assembly870,541,426 - 70,735,701 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

Annotation    (Toggle Detail/Summary View)

Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
  
More on SULF1
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 733350
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2013-05-14
Status: ACTIVE



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