SELP (selectin P (granule membrane protein 140kDa, antigen CD62))

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Keyword

Gene: SELP (selectin P (granule membrane protein 140kDa, antigen CD62)) Homo sapiens

Symbol:

SELP

Name:

selectin P (granule membrane protein 140kDa, antigen CD62)

Description:

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

CD62; CD62 antigen-like family member P; CD62P; FLJ45155; GMP-140; GMP140; granule membrane protein 140; granulocyte membrane protein; GRMP; LECAM3; leukocyte-endothelial cell adhesion molecule 3; OTTHUMP00000032609; OTTHUMP00000032610; OTTHUMP00000032615; OTTHUMP00000032616; OTTHUMP00000032620; OTTHUMP00000032631; OTTHUMP00000032632; OTTHUMP00000032633; P-selectin; PADGEM; platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL

Orthologs:

Mus musculus : Selp (selectin, platelet) MGI
Rattus norvegicus : Selp (selectin P)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	1	176,110,546 - 176,151,831	-	NCBI
Human Genome Assembly HuRef	1	140,780,771 - 140,822,069	-	NCBI
Human Genome Assembly GRCh37	1	169,558,087 - 169,599,377	-	NCBI
Human Genome Assembly Build 36	1	167,824,711 - 167,866,001	-	NCBI
Human Cytogenetic Map	1	q22-q25		NCBI
Human Genome Assembly	1	166,289,747 - 166,331,065		NCBI